Acta medica portuguesa最新文献

{"title":"Translation and Cultural Adaptation of the ISTH-Bleeding Assessment Tool to European Portuguese.","authors":"Diana Carneiro-Leão, Sofia Teixeira, Rita Queirós Pereira, Teresa Mota, Manuela Lopes, Susana Nobre-Fernandes, Fernando Araújo","doi":"10.20344/amp.22374","DOIUrl":"https://doi.org/10.20344/amp.22374","url":null,"abstract":"<p><strong>Introduction: </strong>A distinctive bleeding history is the first diagnostic stage of congenital hemorrhagic diseases. Furthermore, since it is in fact an assessment of the patient's phenotype, it is not a (mere) complementary diagnostic method or test - it is an integral and intrinsic step to establish the patient's clinical history, which is a medical act. The International Society on Thrombosis and Haemostasis-Bleeding Assessment Tool (ISTH-BAT) is a standardized bleeding assessment tool used during the diagnostic workup of suspected bleeding disorders. This study aimed to translate and culturally adapt the ISTH-BAT questionnaire to the European Portuguese language.</p><p><strong>Methods: </strong>The translation and cultural adaptation were based on the International Society for Pharmacoeconomics and Outcomes Research Guidelines and initiated after obtaining permission from the authors. The process involved three English to European Portuguese independent forward translations and a back translation. Discrepancies were gradually resolved. A harmonized version was presented to hemophilia patients and hemophilia carriers for cognitive debriefing.</p><p><strong>Results: </strong>The forward and back translations did not produce important discrepancies. However, some issues were identified in the cognitive debriefing, which led to the cultural adaptation of medical terms for better understanding.</p><p><strong>Conclusion: </strong>A formal translation and cultural adaptation process ensures that the new version maintains the same concepts as the original. After translation, several changes were necessary to ensure that the questionnaire was understandable by non-medical patients. We propose a European Portuguese version of the ISTH-BAT, which will require validation in further studies.</p>","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":"38 2","pages":"75-78"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A AMP Agradece!","authors":"Carlos Cortes, Tiago Villanueva","doi":"10.20344/amp.22857","DOIUrl":"https://doi.org/10.20344/amp.22857","url":null,"abstract":"","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":"38 2","pages":"61-67"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of Chronic Kidney Disease in Adults in Portugal: Practical Recommendations from National Clinical and Laboratory Experts.","authors":"Jorge Malheiro, Rita Birne, André Biscaia, Edgar Almeida, João Nobre, Nuno Capela, Jorge Azinheira, Jorge Nunes Oliveira, Luís Lebre, Manuel Cirne Carvalho, Margarida Albuquerque, Maria José de Sousa, Paulo Paixão, Pedro Freitas, Rita Ribeiro, Rui Pinto, Célia Ramalho, Eduardo Calçada","doi":"10.20344/amp.22557","DOIUrl":"https://doi.org/10.20344/amp.22557","url":null,"abstract":"<p><p>Chronic kidney disease represents a significant public health issue, affecting approximately 9.8% of the adult population in Portugal. Despite this figure, early diagnosis of this disease in high-risk groups remains limited. Although only two parameters are essential for its diagnosis - estimated glomerular filtration rate (eGFR) and albuminuria - in Portugal, over 50% of stage 3 - 5 patients have not undergone simultaneous assessment of eGFR and albumin-uria. The insufficient implementation of the simultaneous assessment of these two metrics results in an inadequate evaluation of high-risk populations. A task force of 17 Portuguese experts from the main medical specialties involved in chronic kidney disease management (Nephrology and Family Medicine) and in Clinical Pathology/Laboratory Medicine (representatives of major national laboratories) convened to develop guidelines aimed at standardizing procedures for the prescribing, determination, reporting, and interpretation of diagnostic parameters (albuminuria and eGFR based on serum creatinine) in Portugal. This effort is based on clinical practice, scientific knowledge, and international recommendations. This national consensus among the key stakeholders in the chronic kidney disease screening and diagnosis process culminated in the development of four practical guidelines. These guidelines will enable the consistent provision of eGFR and albuminuria measurements, regardless of the attending physician's medical specialty, the laboratory, or geographic location. Additionally, through this collective effort, experts want to raise awareness among national authorities to the need of developing new guidelines, based on scientific evidence and clinical practice, to address the underassessment of albuminuria and eGFR in this disease's management.</p>","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":"38 2","pages":"119-124"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pembrolizumab plus Pemetrexed and Platinum in Metastatic Non-Squamous Non-Small Cell Lung Cancer: A Real-Life Study at a Portuguese Centre.","authors":"Maria João Santos, Filipa Ferro, Andrea Machado, Ana Sofia Vilariça, Direndra Hasmucrai, Paula Alves","doi":"10.20344/amp.22126","DOIUrl":"https://doi.org/10.20344/amp.22126","url":null,"abstract":"<p><p>First-line therapy for metastatic non-small-cell lung cancer without targetable mutations is platinum-based chemotherapy plus pembrolizumab if programmed death ligand 1 is < 50%. The aim of this real-life retrospective study is to assess the efficacy and safety of this therapy. This retrospective observational study was conducted at the Pulmonary Oncology Department in Unidade Local de Saúde Santa Maria, in Lisbon, Portugal. We included patients with stage IV non-squamous non-small-cell lung cancer with programmed death ligand 1 < 50% that started pembrolizumab plus platinum and pemetrexed between July 2020 and December 2022. Follow-up was carried out until September 2023. Progression-free survival, overall survival, response rate and safety were evaluated. Sixty-six patients were included. Median age 67 years, 72.7% male, 92.4% performance status 0 - 1, 90.9% current/former smokers. Programmed death ligand 1 < 1% in 63.6%. Median overall and progression-free survival were 12.2 months and 6.7 months, respectively. At the time of the cut-off, 21.2% of patients were alive and progression-free. The objective response rate was 42.4% (partial response). The disease control rate was 69.7%. Adverse events occurred in 92.4%, 43.9% had grade 3 - 4 adverse effects. The most common were anemia (50.0%), neutropenia (40.9%), and asthenia (36.4%). Treatment was discontinued in three patients due to adverse effects. There were no treatment-related deaths reported. With median progression-free survival and overall survival of 6.7 and 12.2 months, respectively, and no new safety signals, these results complement data from clinical trials, providing information from a real-world setting.</p>","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":"38 2","pages":"99-103"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Preserving the Autonomy in Intensive Care Units: Patients Voting for General Elections in Portugal].","authors":"Ana Cochicho Ramalho, Madalena Costa, Pedro Gaspar Da Costa, Simão C Rodeia, Philip Fortuna","doi":"10.20344/amp.22168","DOIUrl":"10.20344/amp.22168","url":null,"abstract":"","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":" ","pages":"127-128"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cutaneous Metastases of Renal Cell Carcinoma: Report of Two Clinical Cases].","authors":"Mélissa M de Carvalho, Margarida Moura Valejo Coelho, Rui Bajanca","doi":"10.20344/amp.22440","DOIUrl":"10.20344/amp.22440","url":null,"abstract":"","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":" ","pages":"125-126"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aquagenic Wrinkling of the Palms in a Patient with Cystic Fibrosis.","authors":"Inês Aparício Martins, Miguel Santos-Coelho, Cândida Fernandes","doi":"10.20344/amp.21948","DOIUrl":"https://doi.org/10.20344/amp.21948","url":null,"abstract":"","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":"38 2","pages":"117-118"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Letter to the Editor Concerning \"Childhood Obesity: The Reality of a Health Center\"].","authors":"Beatriz Morais Pinto, Cristiana Reis, Elsa Neves","doi":"10.20344/amp.22569","DOIUrl":"https://doi.org/10.20344/amp.22569","url":null,"abstract":"","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":"38 2","pages":"130"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[What Skills Should Be Acquired in Pre-School Education?]","authors":"Maria Branca Cunha, Joana Queirós, Inês Vaz Matos, Diana Gonzaga, Ana Carvalho Vaz, Catarina Prior, Sara Soares","doi":"10.20344/amp.22114","DOIUrl":"https://doi.org/10.20344/amp.22114","url":null,"abstract":"","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":"38 2","pages":"71-74"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143370227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Equity in Access to Health Care in Portugal: What Do We Know?]","authors":"Joana Fernandes, Cláudia Furtado, João Pereira","doi":"10.20344/amp.21668","DOIUrl":"10.20344/amp.21668","url":null,"abstract":"<p><p>In Portugal, constitutional and legal norms stipulate that the healthcare system should be organized to ensure equity in access to healthcare. To guarantee this objective, it is usually assumed that individuals from different socio-economic groups presenting equal levels of need should have access to the same level of care. The present narrative review describes current knowledge on this topic. It provides a brief overview of the characteristics of the Portuguese healthcare system, which may influence the achievement of the objective of equity in health care access. The empirical evidence on this issue is also presented. In Portugal, equity in access has not been achieved for most types of health care. Particularly in the case of specialized health care, better-off groups of the population used more care for a given level of need. The situations where inequity exists should be examined and corrected; potential access barriers within the National Health Service should be considered, as the public healthcare system bears the responsibility for ensuring equity.</p>","PeriodicalId":7059,"journal":{"name":"Acta medica portuguesa","volume":" ","pages":"104-111"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}