Acta orthopaedica Belgica最新文献_第2页

Clinicopathological and immunohistochemical analysis of the risk factors of recurrence of atypical lipomatous tumor/well-differentiated liposarcoma of the extremities. 四肢非典型脂肪瘤/高分化脂肪肉瘤复发危险因素的临床病理及免疫组化分析。

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.10536

T Zeniya, M Emori, H Tsuchie, A Teramoto, H Nagasawa, E Mizushima, T Keira, J Shimizu, Y Murahashi, S Sugita, T Hasegawa, N Miyakoshi, T Yamashita

{"title":"Clinicopathological and immunohistochemical analysis of the risk factors of recurrence of atypical lipomatous tumor/well-differentiated liposarcoma of the extremities.","authors":"T Zeniya, M Emori, H Tsuchie, A Teramoto, H Nagasawa, E Mizushima, T Keira, J Shimizu, Y Murahashi, S Sugita, T Hasegawa, N Miyakoshi, T Yamashita","doi":"10.52628/90.4.10536","DOIUrl":"10.52628/90.4.10536","url":null,"abstract":"Atypical lipomatous tumors/well-differentiated liposarcomas (ALT/WDLPS) are low-grade, slow-growing, and locally aggressive tumors. We investigated clinical outcomes and recurrence factors for ALT/WDLPS of the extremities. This is retrospective study across three institutions which included patients who underwent surgery for ALT/WDLPS from 2001 to 2019. We collected the data such as the patient demographics, anatomical locations of the tumors (subcutaneous, intramuscular, intermuscular, upper extreme/lower extremity), immunohistochemical data, and the resected margin status. The following variables were evaluated as potential recurrence factors: age, sex, tumor diameter, anatomical location of the tumor, immunohistochemical results, and resected margins. The 5- year local recurrence-free survival rate (RFS) was calculated and differences in survival were assessed. Sixty-two patients were identified, including 29 men and 33 women. The mean age was 63.7 years (range, 34-82 years). The average maximum tumor diameter was 15.9 cm (range, 5-28 cm). The maximum tumor diameter (≥20 cm) was significantly associated with local recurrence (p=0.042). Ten patients (16.1%) developed local recurrence, and the mean time to recurrence was 48.4 months (range, 5-161 months). In our series of 62 patients, the differences in local recurrences were not statistically significant for age, sex, tumor site, surgical margin (R0 or not) and immunohistochemical results. Tumor diameter ≥20 cm, which was the only identified factor for recurrence.","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"731-737"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is early rehabilitation after Total Knee Replacement better with periarticular cocktail of injection or epidural Ropivacaine? 全膝关节置换术后早期康复，关节周围混合注射或硬膜外罗哌卡因更好吗？

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.13753

J Bhalla, H K Singh Chawla, T Kaur Bindra, G Sahni, T Singh, K Gera

{"title":"Is early rehabilitation after Total Knee Replacement better with periarticular cocktail of injection or epidural Ropivacaine?","authors":"J Bhalla, H K Singh Chawla, T Kaur Bindra, G Sahni, T Singh, K Gera","doi":"10.52628/90.4.13753","DOIUrl":"10.52628/90.4.13753","url":null,"abstract":"TKA is routinely done orthopaedic procedure done that aims at improving the quality of patients' life by providing pain relief, functional improvement and deformity correction. This study aims to study the efficacy and safety of a Periarticular analgesic cocktail including ropivacaine injection and epidural ropivacaine for early rehabilitation after a total knee replacement.Methods: Total of 100 patients divided into two groups, one group received epidural ropivacaine and second group given periarticular cocktail containing ropivacaine. Then postoperatively their pain score comparison using VAS score and their functional status is documented knee society score.Results: The mean age for the epidural group is 60.28 years, while for the periarticular cocktail group it's 60.88 years. For female patients, 34 (68%) received epidural analgesia, while 24 (48%) received periarticular cocktail. Among male patients, 16 (32%) had epidural analgesia, and 26 (52%) received periarticular cocktail. For pre-operative pain scores, patients receiving Epidural analgesia had a slightly higher mean score of 7.24 compared to those receiving Periarticular Cocktail, who had a mean score of 7.12. Patients in the Epidural group had a higher mean knee flexion of 83.84 degrees compared to the Periarticular Cocktail group, which had a mean flexion of 79.36 degrees. The Knee Society Scores (KSS) for the post-operative scores; The Epidural group had a mean score of 80.16. The Periarticular Cocktail group had a mean score of 88.40.Conclusion: In conclusion, this study supports the periarticular analgesic cocktail over epidural analgesia for pain management and early rehabilitation following TKR.","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"613-621"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Low dislocation rate following revision total hip arthroplasty (THA) with dual mobility cup with minimum 2-year follow-up. 双活动杯翻修全髋关节置换术后脱位率低，随访至少2年。

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.12752

Shah Jehan, Aaron By Ng, Simon Ce Jones, Ajit Shetty

{"title":"Low dislocation rate following revision total hip arthroplasty (THA) with dual mobility cup with minimum 2-year follow-up.","authors":"Shah Jehan, Aaron By Ng, Simon Ce Jones, Ajit Shetty","doi":"10.52628/90.4.12752","DOIUrl":"10.52628/90.4.12752","url":null,"abstract":"Dislocation is the second most common indication for revision total hip arthroplasty (THA). In revision cases the dislocation rate can be as high as 5-30%. The aim of this study was to assess the outcome, specifically the dislocation rate in revision THA where a dual mobility cup was used. We retrospectively reviewed all the revision THAs where a dual mobility cup (G7) was used. The pre-operative and post-operative oxford hip scores were recorded. Patients' electronic records and radiographs were studied for the indications, approaches used, post-operative complications, re-operation rates, and re-revision surgery. Between 2016 and 2020, we performed 59 revision total hip replacements where a dual mobility cup (G7) was used. There were 23 males and 36 females. The average age was 74 years (range, 64-89). Acetabular components were revised in 47 (80%) cases and both the femoral and the acetabular components were revised in 12 (20%) cases. The average follow-up time was 4 years (range, 2-6 years). Average pre-operative and post-operative oxford hip scores were 17 and 36 respectively. The improvement was significant with P value of <.001. Complications were noted in 5 (8%) patients. One patient had dislocation. This patient required re-revision with constrained liner. One patient had intraoperative fracture of the femur and was treated with plate and cables. We conclude that the dual mobility cup can significantly reduce the risk of dislocation when used in revision THA.","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"575-579"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Osteoblast Activity and Accelerating Fracture Healing via miR-656-3p Downregulation: A Novel Targeting Strategy Focused on BMP-2 Expression. 通过miR-656-3p下调增强成骨细胞活性和加速骨折愈合：一种专注于BMP-2表达的新靶向策略

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.13790

Shaochun Jing, Fangyuan Zhang, Na Zhao, Xi Wu, Rui Chen

{"title":"Enhancing Osteoblast Activity and Accelerating Fracture Healing via miR-656-3p Downregulation: A Novel Targeting Strategy Focused on BMP-2 Expression.","authors":"Shaochun Jing, Fangyuan Zhang, Na Zhao, Xi Wu, Rui Chen","doi":"10.52628/90.4.13790","DOIUrl":"10.52628/90.4.13790","url":null,"abstract":"Delayed fracture healing (DFH), a common complication of post-fracture surgery, exhibits an incompletely understood pathogenesis. The present study endeavors to investigate the roles and underlying mechanisms of miR-656-3p and Bone Morphogenetic Protein-2 (BMP-2) in DFH. It was recruited 94 patients with normal fracture healing (NFH) and 88 patients with DFH of the femoral neck. Serum miR-656-3p and BMP-2 expressions were quantified using RT-qPCR and the diagnostic potential of them for DFH was evaluated using ROC analysis. Factors influencing fracture healing were identified through logistic regression analysis. Osteogenic differentiation of MC3T3-E1 cells was induced, followed by evaluations of cell proliferation, apoptosis, and differentiation capabilities utilizing CCK-8, flow cytometry, and mRNA expression analysis of osteogenic markers. The targeting relationship between miR-656-3p and BMP-2 was validated through luciferase reporter assays. The levels of miR-656-3p were significantly elevated in DFH patients compared to those with NFH, whereas BMP-2 levels exhibited a decrease, a negative correlation between their expression patterns. Logistic regression analysis revealed that miR-656-3p and BMP-2 serve as influential factors in fracture healing, with their combined assessment exhibiting enhanced predictive value for DFH. Downregulation of miR-656-3p promoted proliferation and differentiation of MC3T3-E1 cells while inhibiting apoptosis. BMP-2, identified as a target of miR-656-3p, negated the effects of miR-656-3p downregulation when BMP-2 expression was inhibited. miR-656-3p modulates osteoblast function by targeting BMP-2, offering novel therapeutic and diagnostic targets for the management of DFH.","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"681-689"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Clinical Efficacy of the Regeneten Bioinductive Implant in Rotator Cuff Repair: A Systematic Review. Regeneten生物诱导植入物在肩袖修复中的临床疗效：系统综述。

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.13834

Marouane Benthami Kbibi, Filip Verhaegen, Philippe Debeer

{"title":"The Clinical Efficacy of the Regeneten Bioinductive Implant in Rotator Cuff Repair: A Systematic Review.","authors":"Marouane Benthami Kbibi, Filip Verhaegen, Philippe Debeer","doi":"10.52628/90.4.13834","DOIUrl":"10.52628/90.4.13834","url":null,"abstract":"Despite advancements in surgical techniques for rotator cuff repair, retear rates remain a significant concern. This study systematically reviews the evidence on the effectiveness of the Regeneten Bioinductive Implant in improving healing outcomes. A systematic review of the literature was conducted by searching on PubMed, Embase, Web of Science Core Collection and Cochrane Library. Studies reporting on effectiveness, safety, radiological, clinical outcomes, or patient- reported outcomes after Regeneten use, with at least 12 months of follow-up, were considered. 17 articles were included in this review, encompassing data on 1062 rotator cuff tears, of which 966 were treated with Regeneten. The implant use resulted in retear rates of 0% up to 18% after 5 years in PT tears and 0% up to 35% after 2 years in FT tears. In 1 randomised trial, the retear rate was significantly lower in the implant group compared to the control group. Constant- Murley Score (CMS) and the American Shoulder and Elbow Surgeons (ASES) score showed a sustained improvement compared to pre-operative scores across all studies. MRI showed increased tendon thickness starting from 6 months, with MRI signals suggesting that the implant was integrating with the native tendon and becoming indistinguishable. While using Regeneten for rotator cuff tears of various sizes and chronicity is associated with reduced retear rates in some studies, the clinical outcomes remain within the same range as those seen with traditional rotator cuff repair. Additional randomized controlled trials are required to validate these results and clarify the appropriate indications for using this implant.","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"777-788"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictive Factors for Lung Metastasis in High-Grade Osteosarcoma: A 5 Years Experience from Tertiary Referral Hospital. 高级别骨肉瘤肺转移的预测因素：来自三级转诊医院的5年经验

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.12808

Y A Prabowo Putro, R Magetsari, Y Oksikimbawan Tampubolon, A Faiz Huwaidi, A Rosfadilla

{"title":"Predictive Factors for Lung Metastasis in High-Grade Osteosarcoma: A 5 Years Experience from Tertiary Referral Hospital.","authors":"Y A Prabowo Putro, R Magetsari, Y Oksikimbawan Tampubolon, A Faiz Huwaidi, A Rosfadilla","doi":"10.52628/90.4.12808","DOIUrl":"10.52628/90.4.12808","url":null,"abstract":"Metastasis stands as one of the most prominent prognostic factors in osteosarcoma. Over 70% of metastatic osteosarcoma occurrences affect the lung. Nonetheless, to date, there has been a scarcity of research addressing predictive factors for lung metastasis risk in osteosarcoma. The objective of this study is to identify the predictive factors that have a role in the risk of lung metastasis in osteosarcoma. This is a retrospective study conducted between January 2018 until January 2023. From the obtained research subjects, an assessment selection was carried out using inclusion and exclusion criteria. Subsequently, preoperative data related to predictive factors will be collected from the research subjects, followed by a clinicopathological conference, chemotherapy, and surgery. Afterward, an evaluation of pulmonary metastasis will be conducted six months after the diagnosis. A total of 47 osteosarcoma patients who met the inclusion and exclusion criteria were analyzed. Bivariate and multivariate logistic regression analyses revealed statistically significant predictive factors for the risk of pulmonary metastasis in osteosarcoma: ALP levels (p=0.014), LDH levels (p=0.038), presence of pathological fractures (p=0.025), and tumor size (p=0.027).","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"739-743"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Translation of a Dutch Version of the Total Shoulder Arthroplasty Postoperative Satisfaction Questionnaire. 全肩关节置换术后满意度问卷的荷兰语翻译。

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.13506

Anke Claes, Cato Boon, Simon Verhaegen, Femke Bosmans, Filip Struyf, Olivier Verborgt

{"title":"Translation of a Dutch Version of the Total Shoulder Arthroplasty Postoperative Satisfaction Questionnaire.","authors":"Anke Claes, Cato Boon, Simon Verhaegen, Femke Bosmans, Filip Struyf, Olivier Verborgt","doi":"10.52628/90.4.13506","DOIUrl":"10.52628/90.4.13506","url":null,"abstract":"To our knowledge, no Dutch questionnaires exist to administer patient satisfaction after total shoulder arthroplasty. The goal of this study is to develop a Dutch translation of the satisfaction questionnaire used by Swarup et al. (2017)1, into Dutch. This ensures the suitability for clinical application an application in research in all Dutch-speaking regions worldwide. A forward-backward translation approach was used. The clarity of the pre-final version was tested on 8-35 post-operative total shoulder arthroplasty patients. The responses of the patients were studied at one single time point. The Dutch translation of the satisfaction questionnaire proposed by Swarup et al. (2017)1 was considered clear to more than 80% of patients, which was set as norm value where the questionnaire can be assumed clear and understable. The Dutch translation of the postoperative satisfaction questionnaire by Swarup et al. (2017)1 met the 80% clarity criterion and can be considered clear. This study provides a base for future research assessing the psychometric properties of this questionnaire.","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"651-657"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Unrecognized Orthopedic Burden of COVID-19: Heterotopic Ossification of the Hip Joint. COVID-19未被认识的骨科负担：髋关节异位骨化。

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.12295

J Jelsma, J R W Crutsen, R Y Jessurun, R Ten Broeke

引用次数: 0

Lateral soft tissue release with distal chevron metatarsal osteotomy in moderate and severe hallux valgus. 中、重度拇外翻侧边软组织松解联合远端跖骨截骨术。

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.12607

Yolanda Hernanz González, Enrique Sánchez Morata, José Carlos Martínez Ávila, Eva García-Jarabo, Guillermo Núñez Ligero, Jesús Vilá Rico

引用次数: 0

Percutaneous Intra-meniscal platelet-rich plasma injection for meniscal tears: A mid-term. 经皮半月板内富血小板血浆注射治疗半月板撕裂：中期研究。

IF 0.5 4区医学

Acta orthopaedica Belgica Pub Date : 2024-12-01 DOI: 10.52628/90.4.13408

Bushu Harna, Shivali Arya, Manish Khanna

{"title":"Percutaneous Intra-meniscal platelet-rich plasma injection for meniscal tears: A mid-term.","authors":"Bushu Harna, Shivali Arya, Manish Khanna","doi":"10.52628/90.4.13408","DOIUrl":"10.52628/90.4.13408","url":null,"abstract":"Percutaneous intra-meniscal platelet-rich plasma (PRP) is a promising tool for managing low-grade meniscal injuries in non-athletic patients. The study evaluates the clinical and radiological outcomes of PRP intra-meniscal injection in meniscal tears. Forty-eight patients were injected with 3 injections of PRP at an interval of one week with a standardised technique under sonographic guidance. All the patients had MRI evidence of meniscal injury with failed conservative management for at least 3 months. The IKDC score and VAS score were recorded initially and during follow-ups. MRI was performed on at least 12 months post-injection. Medial meniscus tear (n=33) was most commonly present. The mean follow-up of the patient was 14.4 months (Range: 12-16 months) except for 1 patient. Horizontal or oblique tears were the most common injury suffered by the patients (n=35). According to MRI classification, 6 patients had grade 1 lesions, 28 patients had grade 2 lesions, and 14 patients had grade 3 lesions. The mean IKDC and VAS scores improved significantly at the last follow-up. Pain at the site of the injection for 1-2 days was the most common adverse effect. Two patients were surgically intervened at 4 and 6 months respectively. Intra-meniscal PRP injection can be a promising modality to manage low-grade meniscal injuries. It is easy, and minimally invasive to manage meniscal tears. Although there was no radiological evidence of healing, clinical improvement was seen in all the patients. Further, long-term randomized studies are required to ascertain the benefits.","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"90 4","pages":"623-628"},"PeriodicalIF":0.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0