Acta orthopaedica Belgica最新文献

{"title":"Pseudotumor After Ceramic-on-Ceramic Total Hip Arthroplasty: A Case Report.","authors":"S Clarebout, E Jansegers, M Maes","doi":"10.52628/92.1.14948","DOIUrl":"10.52628/92.1.14948","url":null,"abstract":"<p><p>Pseudotumors, typically associated with metal-on-metal (MoM) bearings in total hip arthroplasty (THA), have rarely been reported in ceramic-on-ceramic (CoC) THA. This case details the development of a pseudotumor in a 70-year-old female six years after an uneventful CoC THA for osteoarthritis. The patient presented with groin pain and swelling, and imaging revealed a fluid-filled mass at the hip. Aspiration provided temporary relief, but the cyst recurred. Surgical intervention showed no macroscopic wear on the bearing surfaces, but 40cc of fluid was evacuated from the acetabulum after cup removal, confirming an articular origin. Pathology revealed a macrophage-driven pseudotumor without foreign material, suggesting an inflammatory or hypersensitivity response to the ceramic materials. This case underscores the rare but significant occurrence of pseudotumors in CoC THA, emphasizing the need for thorough clinical evaluation, early detection, and intervention, as well as further research to understand the underlying mechanisms.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agreement Between AI Language Models and BOOM Chondrosarcoma Consensus Statements: A Comparative Study.","authors":"A Dünki, Ö Polat","doi":"10.52628/92.1.14560","DOIUrl":"10.52628/92.1.14560","url":null,"abstract":"<p><p>Artificial intelligence (AI) is an exciting development makes life easier and solves many problems in daily life. The Birmingham Orthopaedic Oncology Meeting (BOOM) met in January 2024 with 309 participants from 53 countries to discuss the optimal consensus for chondrosarcomas on 21 questions. The aim of this study was to investigate how reliable the expert statements from the BOOM were compared to ChatGPT-4 and DeepseekR1. 21 questions and consensus statements in the section on chondrosarcomas in the BOOM were extracted. The answers were classified according to the level of evidence and consensus status, taking into account the consensus strength category determined in the meeting. Each statement were written separately for the ChatGPT-4 and DeepseekR1. Consensus questions and answers were written for the AI modules and they were asked to interpret these expressions as ''strongly disagree, disagree, undecided, agree or strongly agree''. BOOM participants reached a strong consensus on 19 questions. The number of people who accepted the proposition for 1 question was 52% and no consensus was reached. ChatGPT-4 and DeepseekR1 responded ''disagree'' for a same question. The level of evidence for that question was ''low to moderate'' and a strong consensus was reached. A significant relationship was found between the responses of ChatGPT-4 and DeepseekR1. ChatGPT-4 and Deepseek expressed more positive opinions in the answers with high levels of evidence, while BOOM participants were able to make stronger consensus decisions by combining their clinical observations with literature knowledge, regardless of level of evidence.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of a Machine Learning Model for Predicting Postoperative Delirium in Elderly Patients with Hip Fracture: A Retrospective Cohort Study.","authors":"Qian Song, Y I Ca, Peng Tian, Shujun Yu, Zhe Han, Jun Wang, Yinguang Zhang, Qiang Dong, Aijun Chao, Jizheng Zhang, Jiaming Zheng, Rong-Jian Lu","doi":"10.52628/92.1.15196","DOIUrl":"10.52628/92.1.15196","url":null,"abstract":"<p><p>Postoperative delirium (POD) is a common and serious complication in elderly hip fracture patients, including those undergoing surgery for femoral neck fractures and intertrochanteric fractures, and is associated with poor clinical outcomes. Early identification of at-risk individuals remains challenging with conventional methods. To develop and validate machine learning models for predicting POD using preoperative variables, and to identify key risk factors, we conducted a retrospective study of 400 patients aged ≥65 years undergoing hip fracture surgery. Five machine learning algorithms were developed and validated using 70-30 split with 10-fold cross-validation. Results demonstrated that POD incidence was 20.0% (80/400). Significant predictors included age (OR=1.06, 95%CI:1.02-1.10), cognitive impairment (OR=2.85, 95%CI:1.70-4.78), hypoalbuminemia (OR=2.32, 95%CI:1.45-3.71), and preoperative waiting time (OR=1.18, 95%CI:1.06-1.32). The Random Forest model demonstrated superior performance (AUC=0.89, accuracy=0.83), outperforming other algorithms (XGBoost AUC=0.87, SVM AUC=0.84, Logistic Regression AUC=0.82, Decision Tree AUC=0.79). Variable importance analysis consistently identified cognitive impairment, hypoalbuminemia, and age as the most prominent predictors across all models. In conclusion, machine learning models, particularly Random Forest, effectively predict POD risk using routine preoperative data. Within our study cohort, machine learning models, particularly Random Forest, showed potential for predicting POD risk using routine preoperative data upon internal validation. The consistent identification of key predictors enables targeted prevention strategies for high- risk elderly hip fracture patients. The broader applicability of the model requires confirmation through external validation in future studies. The consistent identification of key predictors enables targeted prevention strategies for high-risk elderly hip fracture patients.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"≥5 cm Tumor with Cortical Breach Predicts Recurrence and Distinguishes ACT from Enchondroma in Long Bones.","authors":"Aierxiding Aimaiti, Yongqian Wang, Tiao Lin, Zhiqiang Zhao","doi":"10.52628/92.1.15273","DOIUrl":"https://doi.org/10.52628/92.1.15273","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to validate potential clinical and radiological features for distinguishing enchondromas from atypical cartilaginous tumours (ACT) and to analyse the association between maximum tumour diameter and local recurrence of enchondromas. It is important to note that this research serves as a validation cohort rather than proposing a new diagnostic framework.</p><p><strong>Materials and methods: </strong>This retrospective study reviewed the clinical data of 50 patients pathologically diagnosed with enchondroma or ACT and treated in our center between 1 January 2015 and 1 June 2024. Imaging characteristics, recurrence outcomes and other variables were compared among patients, and chi-square tests were used to assess the influence of maximum tumour diameter and other relevant factors on the recurrence rate. This study has been approved by the ethics committee of our institution.</p><p><strong>Results: </strong>Patients with a maximum tumor diameter ≥ 5 cm exhibited a higher recurrence risk (recurrence 8 % vs. non-recurrence 0 %, P = 0.01, P < 0.05). This difference is statistically significant and may aid in distinguishing enchondroma from ACT. Moreover, all recurrent cases exhibited cortical bone destruction, which further validates the importance of this imaging feature as a key differentiating point. The primary treatment consisted of curettage combined with bone grafting, yielding an overall favorable prognosis.</p><p><strong>Discussion: </strong>A maximum tumor diameter of ≥5 cm and cortical bone destruction can be considered important predictive factors for local recurrence, and they may also assist in differentiating between atypical cartilaginous tumors (ACTs) and enchondromas. Based on our findings, we are more inclined to consider lesions ≥5 cm as ACTs, particularly when accompanied by cortical destruction, as these features suggest a more aggressive biological behavior. Therefore, we recommend performing extended curettage combined with intraoperative electrocautery or other effective local adjuvant techniques in such cases to achieve adequate tumor control and reduce the risk of recurrence.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CTHRC1 inhibits the proliferation and promotes apoptosis of osteoarthritis chondrocytes by activating Wnt / ß-Catenin pathway.","authors":"Haifeng Li, Haibo Li, Rabinsh Raj Dahal, Yunlou Jiang, Qian Lu, Shenghai Wang, Ganglian Li, Jiayu Xiao","doi":"10.52628/92.1.14938","DOIUrl":"10.52628/92.1.14938","url":null,"abstract":"<p><p>This study aimed to elucidate the function of CTHRC1 and its linkage to the Wnt/β-catenin signaling pathway in the pathogenesis of osteoarthritis (OA), and to preliminarily explore whether a similar molecular interplay exists in rheumatoid arthritis (RA). We employed an integrated strategy combining bioinformatics, in vitro, and in vivo approaches. Bioinformatic screening of GEO-derived RNA-seq data identified CTHRC1 as a key differentially expressed gene in osteoarthritis. Its functional role was subsequently investigated in OA chondrocyte models, where we measured proliferation (via CCK-8 and EdU assays) and apoptosis (by Western blot analysis of Bax, Bcl-2, and Cleaved Caspase-3), along with key proteins in the Wnt/β-catenin pathway. Furthermore, to assess its relevance to inflammatory arthritis in vivo, we utilized a collagen-induced arthritis (CIA) rat model, evaluating clinical arthritis indices, inflammatory cytokine levels, and joint histopathology by HE staining. We found that CTHRC1 expression was significantly upregulated in OA tissues. Functional enrichment analysis indicated its close association with the Wnt/β-catenin signaling pathway. In vitro experiments confirmed increased CTHRC1 expression in IL-1β-induced OA chondrocytes, while knockdown of CTHRC1 effectively promoted cell proliferation and inhibited apoptosis. Mechanistic studies revealed that the protective effects of CTHRC1 knockdown were reversed by the Wnt/β-catenin pathway agonist BML-284, confirming that CTHRC1 mediates chondrocyte degeneration through activation of this pathway. Furthermore, intra- articular knockdown of CTHRC1 in a CIA rat model significantly alleviated joint swelling, reduced levels of inflammatory factors (IL-1β, IL-6, and TNF-α), and effectively mitigated synovial inflammation and collagen deposition. This study identifies CTHRC1 as an upregulated gene in OA and validates its role in promoting chondrocyte dysfunction. CTHRC1 knockdown reverses these effects by attenuating Wnt/β-catenin signaling, a mechanism confirmed by pharmacological rescue. Preliminary in vivo evidence further suggests a similar pathogenic role in RA. Collectively, CTHRC1 emerges as a potential therapeutic target in arthritis through modulation of the Wnt/β-catenin axis.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periprosthetic joint infection after oncologic mega-implant reconstruction using a 24-hour cefazolin prophylaxis: a monocentric retrospective cohort study.","authors":"R Evrard, A Gorani, R Buzisa Mbuku, H Poilvache, F Bombah, P-L Docquier, J-C Yombi, O Cornu, T Schubert","doi":"10.52628/92.1.15357","DOIUrl":"10.52628/92.1.15357","url":null,"abstract":"<p><p>Periprosthetic joint infection (PJI) is a major complication after oncologic reconstruction with mega-implants. The optimal duration and regimen of antibiotic prophylaxis remain debated, with wide variability in clinical practice. This study aimed to report infection rates and associated risk factors in patients undergoing oncologic mega-implant reconstruction using a standard 24-hour cefazolin-based prophylaxis, similar to conventional arthroplasty. We retrospectively reviewed 107 oncologic mega-implants implanted between 2015 and 2023 at a tertiary referral centre. All patients received a 24-hour cefazolin-based prophylaxis. PJI was defined according to the 2011 Musculoskeletal Infection Society criteria. Patient-, surgical-, tumour-, and peri-hospital- related variables were collected. Infection-free implant survival was assessed using Kaplan-Meier analysis, and univariate analyses identified factors associated with infection. Deep infection occurred in 22 of 107 mega-implants (20.6%), mostly within the first two postoperative years. Infection rates varied by anatomical site, with pelvic reconstructions showing the highest incidence (38.7%), compared with lower-limb (15.2%) and upper-limb (10.0%) reconstructions. Pelvic location (p=0.003), postoperative wound dehiscence (Henderson type 1B; p<0.001), and tumour extension into surrounding soft tissues (p=0.03) were significantly associated with infection. Operating time and hospital stay were longer in infected cases but strongly collinear with pelvic reconstruction. In this cohort, infection rates observed after oncologic mega-implant reconstruction in patients treated with a 24-hour cefazolin-based prophylaxis fell within the range reported in the existing literature. Pelvic reconstructions and compromised soft tissues were associated with higher infection risk, suggesting that a uniform prophylactic strategy may not be appropriate for all anatomical locations, particularly the pelvis.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Volkmann Ischemic Wrist Contracture: A Literature and Case-Based Review of Treatment Modalities with a Focus on Ilizarov Circular Frames.","authors":"I Orfanos, E Kostin, A Kirienko","doi":"10.52628/92.1.14819","DOIUrl":"10.52628/92.1.14819","url":null,"abstract":"<p><p>Volkmann's ischemic contracture is a disabling consequence of compartment syndrome, characterized by irreversible muscle and nerve damage leading to joint deformities and functional impairment. Traditional surgical approaches such as tendon lengthening, neurolysis, and free muscle transfer are often limited in severe cases, especially when soft tissue is compromised. This article reviews current treatment options, focusing on the Ilizarov circular frame as a minimally invasive alternative for managing complex wrist contractures. A narrative review of the literature was conducted to assess treatment modalities for Volkmann's contracture, with emphasis on the Ilizarov method based on distraction histogenesis. Two clinical cases of post-traumatic Grade III wrist flexion contractures were included to illustrate the technique. Diagnostic workup included clinical examination, electromyography (EMG), and MRI. Both patients underwent gradual correction using customized three-ring Ilizarov external fixators. Frame setup, hinge positioning, and postoperative rehabilitation were documented in detail. Review of treatment options for Volkmann's contracture highlights gradual correction as a less invasive, effective alternative. Both patients achieved functional wrist alignment without complications. The technique preserved neurovascular structures and soft tissues, with no skin necrosis, nerve injury, or recurrence observed. These findings support the method's safety and adaptability in complex contractures. The Ilizarov circular frame offers a safe and effective treatment for severe Volkmann's wrist contractures, particularly when conventional surgery is contraindicated. These cases support broader application of circular external fixation in upper limb deformities and highlight the need for further clinical investigation.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Field of View: Enhancing Detection of Orthopaedic Metastases in Cancer Staging.","authors":"A Malouhi, C Spiegel, F Weschenfelder, K G Schrenk, G O Hofmann, W Weschenfelder","doi":"10.52628/92.1.15095","DOIUrl":"10.52628/92.1.15095","url":null,"abstract":"<p><p>The rising prevalence of metastatic bone disease (MBD), driven by improved oncological survival, places increasing demands on accurate staging. Standard computed tomography of the chest, abdomen, and pelvis (CT-CAP) often may fail to identify orthopaedically relevant lesions, which may contribute to pathological fractures and poorer outcomes. A retrospective single-centre review was conducted of 135 patients who underwent surgery for non- spinal MBD between 2005 and 2024. Preoperative staging imaging was re-evaluated to assess lesion visibility, anatomical distribution, and detection rates across modalities. Lesions were analysed with respect to fracture occurrence, Mirels scores, and postoperative survival. Interobserver agreement for Mirels scoring was calculated. Survival was analysed using Kaplan-Meier methods and a multivariate Cox proportional hazards model. Lesions not identified on staging imaging were associated with significantly higher rates of pathological fracture (p = 0.01) and shorter postoperative survival (median 6 vs. 25 months, p = 0.03). CT-CAP detected fewer orthopaedically relevant lesions than alternative imaging modalities in this retrospective real-world cohort (p < 0.01). Seven clinically relevant lesions were visible only on CT scout images but lay outside the diagnostic field of view; four subsequently fractured. Detection varied by anatomical region, with proximal femoral lesions identified most frequently. In this retrospective cohort, reliance on CT-CAP alone was associated with missed clinically significant MBD lesions, particularly outside the standard field of view. Routine review of full-body scout images may improve detection and potentially reduce preventable fractures. Integration of automated analysis techniques could further strengthen diagnostic accuracy.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platelet-Derived Extracellular Vesicle - Rich Plasma Demonstrates Favorable Histological Features Compared With PRP in a Rabbit Skeletal Muscle Injury Model.","authors":"M Agir, B Guler, M Sarikas, B Toker, I Tuncay, T Erden","doi":"10.52628/92.1.15062","DOIUrl":"https://doi.org/10.52628/92.1.15062","url":null,"abstract":"<p><p>Platelet-rich plasma (PRP) is commonly used to support skeletal muscle healing, although its efficacy remains variable and concerns persist regarding profibrotic effects. Platelet-derived extracellular vesicles (pEVs) may modulate inflammation, and this study aimed to compare the histological effects of two PRP systems and a pEV-rich plasma preparation in a rabbit muscle injury model. A standardized partial muscle injury (5 × 5 mm) was created in the biceps femoris of 28 female New Zealand White rabbits. Animals were allocated to four groups: control, Arthrex ACP®, T-LAB PRP®, and platelet-derived extracellular vesicle-rich plasma (Exomine®). Treatments were administered locally on postoperative days 0, 4, and 7. Half of the animals were euthanized at week 3 and the remainder at week 6. Histological evaluation focused on inflammatory infiltration, fibrotic scar formation, and indicators of muscle regeneration. At week 3, overall group comparisons showed significant differences in acute inflammatory parameters, with the pEV-rich plasma group exhibiting lower neutrophil infiltration and fewer multinucleated giant cells. At week 6, significant differences were observed in chronic inflammation and remodeling, with reduced lymphocyte-macrophage infiltration and fibrosis in the pEV-rich plasma group. Both PRP groups showed histological findings comparable to control. In this preclinical rabbit model, a platelet-derived extracellular vesicle-rich plasma preparation was associated with more favorable histological features related to inflammation resolution and fibrosis than conventional PRP. These findings are limited to histopathological outcomes and require confirmation with functional studies.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Sustentaculum Tali Sustentacular Screw Length based on Linear Regression Model.","authors":"Guangsheng Tang, Bing Wang, Jianning Sun, Yao Xu, Deguang Wang","doi":"10.52628/92.1.14550","DOIUrl":"10.52628/92.1.14550","url":null,"abstract":"<p><p>Calcaneal fractures present challenges due to the complex anatomy and difficulty in achieving precise screw placement. Traditional methods often rely on empirical screw insertion, leading to complications like joint penetration or nerve damage. We selected 66 adult calcaneus specimens and conducted analyses using micro-CT scanning and anatomical measurement techniques, dividing the calcaneus into the anterior, middle, posterior, and ST regions. The calcaneus was divided into anterior, middle, posterior, and ST regions. Linear regression was used to analyze the relationship between anatomical parameters and the lengths of screws for the posterior facet (PF) and articulatio calcaneocuboidea (AC). The derived models for AC/PF screw length based on CT data are: G1 = -1.96 + 0.71F1 + 0.48F8 + 0.39F9 (AC screw) and G2 = 3.95 + 0.28F1 + 0.59F8 + 0.31F9 (PF screw), with similar results for anatomical data. Predicted screw lengths were validated through Micro-CT imaging, confirming accurate insertion without perforating the medial calcaneal cortex. In conclusion, linear regression models based on Micro-CT and anatomical data can accurately predict AC/PF screw lengths, improving surgical precision and outcomes. Meanwhile, we'll keep collecting more data to validate and improve the models. Additionally, we'll explore new methods like machine learning to enhance prediction accuracy in the future. Study design: Experimental cadaveric study with anatomical and Micro-CT-based measurements.</p>","PeriodicalId":7018,"journal":{"name":"Acta orthopaedica Belgica","volume":"92 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147727951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}