Acta medica Okayama最新文献_第7页

Can Pelvic Lymph Node Dissection in Prostate Cancer Patients with a 5% Briganti Nomogram Cut-off Value Provide an Oncological Benefit? A Large Multi-Institutional Cohort Study in Japan. 5% Briganti Nomogram 临界值的前列腺癌患者盆腔淋巴结清扫能带来肿瘤学获益吗？日本一项大型多机构队列研究。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67546

Naoya Sugihara, Katsuyoshi Hashine, Natsumi Yamashita, Miki Sakamoto, Masato Terashita, Keisuke Funaki, Kaori Saiki, Takatora Sawada, Toshio Kakuda, Kenichi Nishimura, Tetsuya Fukumoto, Noriyosi Miura, Yuki Miyauchi, Tadahiko Kikugawa, Takashi Saika

{"title":"Can Pelvic Lymph Node Dissection in Prostate Cancer Patients with a 5% Briganti Nomogram Cut-off Value Provide an Oncological Benefit? A Large Multi-Institutional Cohort Study in Japan.","authors":"Naoya Sugihara, Katsuyoshi Hashine, Natsumi Yamashita, Miki Sakamoto, Masato Terashita, Keisuke Funaki, Kaori Saiki, Takatora Sawada, Toshio Kakuda, Kenichi Nishimura, Tetsuya Fukumoto, Noriyosi Miura, Yuki Miyauchi, Tadahiko Kikugawa, Takashi Saika","doi":"10.18926/AMO/67546","DOIUrl":"https://doi.org/10.18926/AMO/67546","url":null,"abstract":"The Briganti nomogram (cut-off value 5%) is commonly used to determine the indications for pelvic lymph node dissection (PLND) in patients with prostate cancer. We retrospectively analyzed the potential oncological benefit of PLND based on the 5% cut-off value on the Briganti nomogram. We obtained the data from the Medical Investigation Cancer Network (MICAN) Study, which included 3,463 patients who underwent a radical prostatectomy (RP) at nine institutions in Japan between 2010 and 2020. We included patients with Briganti scores ≥ 5% and a follow-up period ≥6 months and excluded patients categorized in the very high-risk group (based on NCCN categories); a final total of the cases of 1,068 patients were analyzed. The biochemical recurrence (BCR)-free survival was significantly worse in the patients who underwent PLND compared to those who did not (p=0.019). A multivariate analysis showed that high prostate-specific antigen (PSA) levels (p<0.001) and an advanced T-stage (p=0.018) were significant prognostic factors for BCR, whereas PLND had no effect on BCR (p=0.059). Thus, PLND in patients with prostate cancer whose Briganti score was 5% did not provide any oncological benefit. Further research is necessary to determine the indication criteria for conducting PLND.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"307-312"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumocephalus with Inverted Papilloma in the Frontoethmoidal Sinus: Case Report and Literature Review. 前牙状窦倒置乳头状瘤引发的气胸：病例报告和文献综述。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67550

Seiichiro Makihara, Yoshihiro Otani, Kensuke Uraguchi, Sawako Ono, Aiko Shimizu, Ryosuke Ikemachi, Yosuke Okazaki, Tomoyuki Ota, Hiroshi Matsumoto, Shotaro Miyamoto, Munechika Tsumura, Seiya Hayashi, Michiari Umakoshi, Koji Hirashita, Mizuo Ando

引用次数: 0

A Rare Subglottic Pleomorphic Adenoma: Magnetic Resonance Findings. 罕见的声门下多形性腺瘤：磁共振检查结果

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67549

Chieko Furukawa, Tomoyasu Tachibana, Tetsuji Nobuhisa, Yuichiro Kanie, Yoji Wani, Jun-Ya Matsumoto, Akifumi Kariya, Asuka Sato, Iichiro Ishikawa, Yuto Naoi, Mizuo Ando

引用次数: 0

Surgical Treatment of an Abdominal Aortic Aneurysm in a Patient with a Liver Abscess. 肝脓肿患者腹主动脉瘤的手术治疗。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67553

Gentaro Kato, Yuto Narumiya, Michihiro Okuyama, Shuji Shimizu, Kenji Sangawa, Shu Yamamoto

引用次数: 0

Multicenter Remote-Access Simulation of Vaginal Delivery for High-Flexibility Medical Education during the Coronavirus Pandemic. 多中心远程访问模拟阴道分娩，在冠状病毒大流行期间开展高灵活性医学教育。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67547

Eriko Eto, Jota Maki, Noriyuki Yamashita, Toru Hasegawa, Ayano Suemori, Hikari Nakato, Hikaru Oba, Tomohiro Mitoma, Sakurako Mishima, Satoe Kirino, Akiko Ohira, Hisashi Masuyama

{"title":"Multicenter Remote-Access Simulation of Vaginal Delivery for High-Flexibility Medical Education during the Coronavirus Pandemic.","authors":"Eriko Eto, Jota Maki, Noriyuki Yamashita, Toru Hasegawa, Ayano Suemori, Hikari Nakato, Hikaru Oba, Tomohiro Mitoma, Sakurako Mishima, Satoe Kirino, Akiko Ohira, Hisashi Masuyama","doi":"10.18926/AMO/67547","DOIUrl":"https://doi.org/10.18926/AMO/67547","url":null,"abstract":"During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku-Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered \"satisfied\" or \"very satisfied\" with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"313-322"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Middle-Ear Salivary Gland Choristoma with Congenital, Single-Sided Hearing Loss. 中耳唾液腺瘤伴先天性单侧听力损失

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67554

Yuichiro Tominaga, Akiko Sugaya, Shin Kariya, Aiko Shimizu, Yuko Kataoka, Mizuo Ando

引用次数: 0

Effect of Recipient Age on Perioperative Complications after Pediatric Liver Transplantation: A Single-Center Retrospective Study. 受体年龄对小儿肝移植术后围手术期并发症的影响：单中心回顾性研究

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-08-01 DOI: 10.18926/AMO/67548

Akira Katayama, Satoshi Kimura, Takashi Matsusaki, Hiroshi Morimatsu

{"title":"Effect of Recipient Age on Perioperative Complications after Pediatric Liver Transplantation: A Single-Center Retrospective Study.","authors":"Akira Katayama, Satoshi Kimura, Takashi Matsusaki, Hiroshi Morimatsu","doi":"10.18926/AMO/67548","DOIUrl":"https://doi.org/10.18926/AMO/67548","url":null,"abstract":"It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 4","pages":"323-330"},"PeriodicalIF":0.6,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142091385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Gallbladder Metastasis of Malignant Melanoma. 一例恶性黑色素瘤胆囊转移。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67205

Hitoshi Minagi, Hideki Aoki, Susumu Doita, Eiki Miyake, Toshihiro Ogawa, Fumitaka Taniguchi, Megumi Watanabe, Takashi Arata, Koh Katsuda, Kohji Tanakaya

引用次数: 0

Effect of Lipopolysaccharide on the Duration of Zolpidem-Induced Loss of Righting Reflex in Mice. 脂多糖对唑吡坦诱导小鼠丧失向右转反射持续时间的影响

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67197

Yudai Wada, Soichiro Ushio, Yoshihisa Kitamura, Yoshito Zamami, Toshiaki Sendo

{"title":"Effect of Lipopolysaccharide on the Duration of Zolpidem-Induced Loss of Righting Reflex in Mice.","authors":"Yudai Wada, Soichiro Ushio, Yoshihisa Kitamura, Yoshito Zamami, Toshiaki Sendo","doi":"10.18926/AMO/67197","DOIUrl":"https://doi.org/10.18926/AMO/67197","url":null,"abstract":"Zolpidem, a non-benzodiazepine hypnotic, is primarily used to treat insomnia. In a previous study, pior treatment with non-benzodiazepine receptor agonists was associated with inflammation. The present study aimed to clarify the association between the effects of zolpidem and inflammation in mice treated with lipopolysaccharide (LPS), a known model of inflammation. We assessed the zolpidem-induced loss of righting reflex (LORR) duration 24 h after LPS treatment in mice. Additionally, the expressions of γ-aminobutyric acid (GABA)A receptor subunit and K+-Cl- cotransporter isoform 2 (KCC2) mRNA in the hippocampus and frontal cortex were examined in LPS-treated mice. Pretreatment with LPS was associated with significantly prolonged duration of zolpidem-induced LORR compared to control mice. This effect was significantly attenuated by administering bicuculline, a GABAA receptor antagonist, or flumazenil, a benzodiazepine receptor antagonist, in LPS-treated mice. Compared to controls, LPS-treated mice showed no significant change in the expression of GABAA receptor subunits in the hippocampus or frontal cortex. Bumetanide, an Na+-K+-2Cl- cotransporter isoform 1 blocker, attenuated the extended duration of zolpidem-induced LORR observed in LPS-treated mice. LPS significantly decreased Kcc2 mRNA expression in the hippocampus and the frontal cortex. These findings suggest that inflammation increases zolpidem-induced LORR, possibly through a reduction in KCC2 expression.","PeriodicalId":7017,"journal":{"name":"Acta medica Okayama","volume":"78 3","pages":"227-235"},"PeriodicalIF":0.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organized Chronic Subdural Hematoma (OCSDH) Mimicking Meningioma. 模仿脑膜瘤的有组织慢性硬膜下血肿 (OCSDH)。

IF 0.6 4区医学

Acta medica Okayama Pub Date : 2024-06-01 DOI: 10.18926/AMO/67204

Shuichiro Hirano, Yoshihiro Otani, Kentaro Fujii, Isao Date

引用次数: 0