Chemistry Education Research and Practice最新文献_第10页

Combatting the HIV reservoir 抗击艾滋病病毒库。

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-03-07 DOI: 10.1038/s41579-024-01039-9

Agustina Taglialegna

引用次数: 0

Blasting away a fungal pathogen 清除真菌病原体

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-03-07 DOI: 10.1038/s41579-024-01038-w

Agustina Taglialegna

引用次数: 0

The origins of pathogenesis 发病机制的起源。

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-03-05 DOI: 10.1038/s41579-024-01034-0

Salvador Almagro-Moreno

引用次数: 0

The coral microbiome in sickness, in health and in a changing world 疾病、健康和不断变化的世界中的珊瑚微生物群。

IF 69.2 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-03-04 DOI: 10.1038/s41579-024-01015-3

Christian R. Voolstra, Jean-Baptiste Raina, Melanie Dörr, Anny Cárdenas, Claudia Pogoreutz, Cynthia B. Silveira, Amin R. Mohamed, David G. Bourne, Haiwei Luo, Shady A. Amin, Raquel S. Peixoto

{"title":"The coral microbiome in sickness, in health and in a changing world","authors":"Christian R. Voolstra, Jean-Baptiste Raina, Melanie Dörr, Anny Cárdenas, Claudia Pogoreutz, Cynthia B. Silveira, Amin R. Mohamed, David G. Bourne, Haiwei Luo, Shady A. Amin, Raquel S. Peixoto","doi":"10.1038/s41579-024-01015-3","DOIUrl":"10.1038/s41579-024-01015-3","url":null,"abstract":"Stony corals, the engines and engineers of reef ecosystems, face unprecedented threats from anthropogenic environmental change. Corals are holobionts that comprise the cnidarian animal host and a diverse community of bacteria, archaea, viruses and eukaryotic microorganisms. Recent research shows that the bacterial microbiome has a pivotal role in coral biology. A healthy bacterial assemblage contributes to nutrient cycling and stress resilience, but pollution, overfishing and climate change can break down these symbiotic relationships, which results in disease, bleaching and, ultimately, coral death. Although progress has been made in characterizing the spatial-temporal diversity of bacteria, we are only beginning to appreciate their functional contribution. In this Review, we summarize the ecological and metabolic interactions between bacteria and other holobiont members, highlight the biotic and abiotic factors influencing the structure of bacterial communities and discuss the impact of climate change on these communities and their coral hosts. We emphasize how microbiome-based interventions can help to decipher key mechanisms underpinning coral health and promote reef resilience. Finally, we explore how recent technological developments may be harnessed to address some of the most pressing challenges in coral microbiology, providing a road map for future research in this field. In this Review, Voolstra, Raina, Peixoto and colleagues discuss our current knowledge of the function and role of the bacterial microbiome in coral health and disease, and elucidate the response of the host-associated bacteria to global change, which bears implications for coral reef conservation.","PeriodicalId":69,"journal":{"name":"Chemistry Education Research and Practice","volume":"22 8","pages":"460-475"},"PeriodicalIF":69.2,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conservation and similarity of bacterial and eukaryotic innate immunity 细菌和真核生物先天免疫的一致性和相似性

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-02-28 DOI: 10.1038/s41579-024-01017-1

Hannah E. Ledvina, Aaron T. Whiteley

{"title":"Conservation and similarity of bacterial and eukaryotic innate immunity","authors":"Hannah E. Ledvina, Aaron T. Whiteley","doi":"10.1038/s41579-024-01017-1","DOIUrl":"10.1038/s41579-024-01017-1","url":null,"abstract":"Pathogens are ubiquitous and a constant threat to their hosts, which has led to the evolution of sophisticated immune systems in bacteria, archaea and eukaryotes. Bacterial immune systems encode an astoundingly large array of antiviral (antiphage) systems, and recent investigations have identified unexpected similarities between the immune systems of bacteria and animals. In this Review, we discuss advances in our understanding of the bacterial innate immune system and highlight the components, strategies and pathogen restriction mechanisms conserved between bacteria and eukaryotes. We summarize evidence for the hypothesis that components of the human immune system originated in bacteria, where they first evolved to defend against phages. Further, we discuss shared mechanisms that pathogens use to overcome host immune pathways and unexpected similarities between bacterial immune systems and interbacterial antagonism. Understanding the shared evolutionary path of immune components across domains of life and the successful strategies that organisms have arrived at to restrict their pathogens will enable future development of therapeutics that activate the human immune system for the precise treatment of disease. In this Review, Ledvina and Whiteley highlight the key similarities between eukaryotic and bacterial innate immune systems, exploring conserved immune components and signalling strategies, as well as conserved mechanisms for pathogen restriction.","PeriodicalId":69,"journal":{"name":"Chemistry Education Research and Practice","volume":"22 7","pages":"420-434"},"PeriodicalIF":88.1,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139987538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monitoring pathogens in wastewater 监测废水中的病原体

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-02-27 DOI: 10.1038/s41579-024-01033-1

Arin Wongprommoon, Chalita Chomkatekaew, Claire Chewapreecha

引用次数: 0

Author Correction: Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa 作者更正：非洲疟疾寄生虫青蒿素部分抗药性的出现、传播动态和机制。

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-02-27 DOI: 10.1038/s41579-024-01032-2

Philip J. Rosenthal, Victor Asua, Melissa D. Conrad

引用次数: 0

A potential new player in gastric cancer 胃癌的潜在新参与者

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-02-21 DOI: 10.1038/s41579-024-01027-z

Agustina Taglialegna

引用次数: 0

Breaking the mould: rethinking ‘wild type’ in fungal pathogens 打破模式：重新思考真菌病原体中的 "野生型"。

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-02-16 DOI: 10.1038/s41579-024-01024-2

Amelia E. Barber

引用次数: 0

Inactive vents, active producers 不活跃的通风口，活跃的生产者。

IF 88.1 2区教育学

Chemistry Education Research and Practice Pub Date : 2024-02-14 DOI: 10.1038/s41579-024-01022-4

Agustina Taglialegna

引用次数: 0