Acta biologica et medica Germanica最新文献_第10页

Universal structural features of prokaryotic and eukaryotic ribosomal 5S RNA derived from comparative analysis of their sequences. 原核与真核核糖体5S RNA序列的比较分析。

Acta biologica et medica Germanica Pub Date : 1982-01-01

S Böhm, H Fabian, H Welfle

{"title":"Universal structural features of prokaryotic and eukaryotic ribosomal 5S RNA derived from comparative analysis of their sequences.","authors":"S Böhm, H Fabian, H Welfle","doi":"","DOIUrl":"","url":null,"abstract":"An extensive comparative analysis of more than fifty available sequences of ribosomal 5S RNA has been made. Both for prokaryotic and eukaryotic 5S RNA a generalized secondary structure is presented which is similar to that suggested by Nishikawa and Takemura modified in few positions only. Both generalized secondary structures contain five main helical regions and a high base-pairing content of about 65 +/- 5%. The general structural architecture of prokaryotic and eukaryotic 5S RNA molecules appears to be very similar with minor modifications within particular subgroups of organisms. Conserved and semiconserved nucleotides are accumulated in the single stranded parts of 5S RNA. Functional importance was suggested for some of these regions; other short conserved nucleotide stretches may be involved in the folding of 5S RNA molecules. In particular, we propose a tertiary base-pairing interaction between the universal invariant GUA sequence (positions 76-78 and 75-77 in prokaryotic and eukaryotic 5S RNA, respectively) and the complementary conserved CPuU sequence (positions 38-40 and 36-38) in a parallel manner. A molecular model of the 5S RNA of human KB cells was constructed, which verifies the proposed tertiary interaction, probably stabilizing the two neighboured helices E and D and a stacking arrangement of the bases in the sequence positions 67-108 (and 70-106) in eukaryotic (and prokaryotic) 5S RNAs, respectively.","PeriodicalId":6985,"journal":{"name":"Acta biologica et medica Germanica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18128832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autophagocytosis: freeze-fracture morphology, effects of vinblastine and influence of transcriptional and translational inhibitors. 自噬:冷冻断裂形态、长春花碱的作用以及转录和翻译抑制剂的影响。

Acta biologica et medica Germanica Pub Date : 1982-01-01

J Kovács, G Réz, A L Kovács, J Csák, G Zboray

引用次数: 0

Influence of anti-rheumatic drugs on the activity of collagenolytic cathepsin in hepatic culture. 抗风湿药物对肝组织蛋白酶活性的影响。

Acta biologica et medica Germanica Pub Date : 1982-01-01

E Kucharz, B Stawiarska, M Drozdz

引用次数: 0

Effect of linoleic acid-rich diet on blood pressure, lipids, catecholamines, and dopamine -beta-hydroxylase in spontaneously hypertensive rats. 富亚油酸饮食对自发性高血压大鼠血压、血脂、儿茶酚胺和多巴胺- β -羟化酶的影响。

Acta biologica et medica Germanica Pub Date : 1982-01-01

P Singer, V Moritz, D Förster, S Voigt, M Wirth, E Naumann, S Zimontkowski

{"title":"Effect of linoleic acid-rich diet on blood pressure, lipids, catecholamines, and dopamine -beta-hydroxylase in spontaneously hypertensive rats.","authors":"P Singer, V Moritz, D Förster, S Voigt, M Wirth, E Naumann, S Zimontkowski","doi":"","DOIUrl":"","url":null,"abstract":"Spontaneously hypertensive rats (SHR) and normotensive Wistar rats were fed a linoleic acid-rich (LAR) and -deficient (LAD) diet for 22 weeks, respectively. Although linoleic acid (LA) and arachidonic acid (AA) in serum and liver triglycerides markedly increased after a LAR diet, LA was significantly lower and AA was higher in SHR when compared to normotensive control rats. Thus, the percentage of both fatty acids remained different like in animals fed a commercial diet. On the contrary, in SHR and normotensive rats fed a LAD diet no differences in the LA and AA content could be found between the groups. In these rats, however, n-3 fatty acids (eicosapentaenoic and docosahexaenoic acids) in serum triglycerides were increased. Blood pressure, serum triglycerides and total cholesterol appeared unchanged, whereas HDL-cholesterol was increased after a LAR diet. Dopamine, adrenaline and noradrenaline content as well as dopamine-beta-hydroxylase activity were augmented in adrenal glands of SHR fed a LAR diet. In spite of distinct biochemical alterations the genetically determined hypertension in rats could not be influenced by a long-lasting diet containing a high amount of LA which has been proved to be effective on lowering blood pressure in other hypertensive rat models.","PeriodicalId":6985,"journal":{"name":"Acta biologica et medica Germanica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18129833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Diet induced changes of Ca-regulation in rabbit papillary muscle. 1. Contraction and relaxation following a cholesterol diet]. 饮食对兔乳头肌钙调节的影响。1. 胆固醇饮食后的收缩和放松]。

Acta biologica et medica Germanica Pub Date : 1982-01-01

J Günther, E Kutscherskij, E Storch, R Vetter

引用次数: 0

[A new human Gm reaction type, tested on bovine serum]. [一种新的人类转基因反应类型，在牛血清上测试]。

Acta biologica et medica Germanica Pub Date : 1982-01-01

R Kirst

引用次数: 0

[Isolation of an alpha-globulin from rabbit serum responsible for a cobalt(II) ion-induced change in conformation of fibrinogen]. [从兔血清中分离出一种导致钴离子诱导纤维蛋白原构象改变的α -球蛋白]。

Acta biologica et medica Germanica Pub Date : 1982-01-01

S Krantz, M Lober, I Herrmann

引用次数: 0

[Degradation of inactivated alpha-amylase by associated proteases]. [相关蛋白酶对失活α -淀粉酶的降解]。

Acta biologica et medica Germanica Pub Date : 1982-01-01

R Ulbrich, G Kvesitadze, A Schellenberger

引用次数: 0

[Tolerance induction and production of anti-idiotypic antisera in carp]. 鲤鱼的耐受性诱导及抗独特型抗血清的产生。

Acta biologica et medica Germanica Pub Date : 1982-01-01

R F Richter, M Schirbock, H Ambrosius

引用次数: 0

[Perinatal development of glucose-6-phosphatase and fructose-1,6-diphosphatase activities in pig liver]. [围产期猪肝脏中葡萄糖-6-磷酸酶和果糖-1,6-二磷酸酶活性的变化]。

Acta biologica et medica Germanica Pub Date : 1982-01-01

E Grün, D Heyne

{"title":"[Perinatal development of glucose-6-phosphatase and fructose-1,6-diphosphatase activities in pig liver].","authors":"E Grün, D Heyne","doi":"","DOIUrl":"","url":null,"abstract":"The activity of glucose-6-phosphatase (G6Pase) and fructose-1,6-bisphosphatase (FDPase) was determined in the homogenate of the liver of 69 pig fetuses during the last third of gestation (80th to 114th day), 47 piglets from birth to 4 weeks old (suckling period) and to slaughter pigs. G6Pase is evident in fetal liver at an early date and raises steadily during gestation. In newborn piglets, the enzyme activity increases rapidly during the first hours of life and remains at this high level during the first week of life. Afterwards the enzyme activity returns to birth level, which exists also in pigs at slaughtering. The activity of FDPase is constant during the fetal period. After birth enzyme activity rises at a lower rate than the G6Pase during the first week of life. This level remains constant during the suckling period and increases thereafter until the time of slaughtering of pigs. The role of hormones in the perinatal development of these enzymes is described. Probably, thyroxine causes the prenatal increase of the activity of both the enzymes. The rapid postnatal rise of G6Pase activity may be induced by the high level of hydrocortisone at parturition, and furthermore, glucagon may have a permissive effect.","PeriodicalId":6985,"journal":{"name":"Acta biologica et medica Germanica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17354941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0