E. Oyinloye, A. Aderinola, Abdullahi Muritala, W. Olooto
{"title":"Protective role of dichloromethane extract of solanum dasyphyllumin in gentamicin induced nephrotoxicity in mice","authors":"E. Oyinloye, A. Aderinola, Abdullahi Muritala, W. Olooto","doi":"10.23893/1307-2080.aps.05826","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05826","url":null,"abstract":"","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68931720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vitro antifungal activity of cistus creticus l. against plant pathogenic fungi","authors":"A. Caskurlu, A. Karadaǧ, Y. Köse, F. Tosun","doi":"10.23893/1307-2080.aps.05822","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05822","url":null,"abstract":"","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68931570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytotoxic effect of some furanosesquiterpenes from balsamodendron myrrha nees. oleo-gum-resin on brine shrimp (artemia salina) larvae ayesha asif1,","authors":"A. Asif, M. Saeed","doi":"10.23893/1307-2080.aps.05824","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05824","url":null,"abstract":"","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68931639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of the diabetic patients\" knowledge on diabetes and the role of clinical pharmacist in providing pharmaceutical care to them","authors":"N. Taner, M. E. Tatlıpınar, A. Aydın, G. Omurtag","doi":"10.23893/1307-2080.aps.05827","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05827","url":null,"abstract":"","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68931742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular drug design and docking study of novel n- substituted celecoxib derivatives as selective cyclooxygenase-2 inhibitors","authors":"M. Ezzat, B. A. Razik","doi":"10.23893/1307-2080.aps.05823","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05823","url":null,"abstract":"","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68931581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determination amount of silymarin and pharmaceutical products from milk thistle waste obtained from cold press","authors":"Derya Duran, S. Ötleş, E. Karasulu","doi":"10.23893/1307-2080.aps.05706","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05706","url":null,"abstract":"Silybum marianum (L.) Gaertn (synonym Carduus marianus L.) is known as milk thistle. It belongs to Asteraceae family. It originates from the Mediterranean area. However, it has spread to other countries in Europe, Asia, Australia and both Americas1. The primary content of S. marianum is the presence of a group of flavonolignans known as silymarin in the pericarp and seed coat 2. The rate of flavonolignans is usually between 1.5% and 3.5% of the fruit weight1. Silymarin consists of silybin, isosilybin, silydianin, silychristin, isosilychrystin and isosilybinin1.3. Since among flavonolignan compounds silybin has detoxificationing ABSTRACT","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68930188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Aremu, John Paul Adjuzie, O. Olayemi, J. E. Okoh, K. Ekere, O. Fatokun, M. Emeje
{"title":"Formulation and evaluation of acetylsalicylic acid suppositories using capra hircus (goat) fat and its binary blends","authors":"O. Aremu, John Paul Adjuzie, O. Olayemi, J. E. Okoh, K. Ekere, O. Fatokun, M. Emeje","doi":"10.23893/1307-2080.aps.05725","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05725","url":null,"abstract":"A study has been made on the formulation and evaluation of Acetylsalicylic acid (ASA) suppositories using Goat fat (GF) and its binary blends with Palm Kernel oil and Liquid Paraffin. Cocoa butter was used as the standard reference suppository base. Rectal suppositories containing ASA (300 mg) in pre-calibrated mould were prepared by fusion method and evaluated for appearance, crushing strength, weight variation, melting point, liquefaction time, content uniformity and in-vitro release using standard procedures. Liquefaction or disintegration time (minutes) followed this order: ACB(4.40±0.84) <AGL(6.20±0.83) <AGP(7.14±0.84) < AGF(11.45±2.20) while cumulative drug release (%) is AGP> AGF >AGL>ACB (p<0.05). Results obtained indicated that the bases used generally could be ranked in the order of GL > GP > GF > CB (p<0.05) in terms of favourable physicochemical properties investigated. The foregoing indicates that GL or GP has promising potential and could be a substitute suppository base in the formulation of ASA suppositories.","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68930977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Flax seed mucilage-chitosan polyelectrolyte complex nanoparticles: optimization, characterization and evaluation","authors":"M. Bhatia, Sunidhi Lohan","doi":"10.23893/1307-2080.aps.05716","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05716","url":null,"abstract":"Flax (Linum usitatissimum), also known as common flax or linseed consists of the dried fully ripe seeds of the genus Linum belonging to family Linaceae 1. Chemically, it contains d-galacturonic acid, l-rhamnose, l-galactose, and dxylose. It is gluten free and also rich in omega-3, omega-6, α-linolenic acid, lignans, high quality proteins and fibers. The flax seed mucilage has been widely ABSTRACT","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68931396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and validation of uplc method for the determination of olopatadine hydrochloride in polymeric nanoparticles","authors":"U. Güven, M. Berkman, Y. Yazan","doi":"10.23893/1307-2080.aps.05701","DOIUrl":"https://doi.org/10.23893/1307-2080.aps.05701","url":null,"abstract":"The conventional eye drops are the most convenient and patient compliant non-invasive route for topical ophthalmic drug delivery. Nasolachrymal drainage, epithelial membrane barriers and non-productive absorption of these ophthalmic preparations can result in poor ocular bioavailability and systemic absorption leading side effects. The limited duration time requires frequently dosing up to 4 times per day for many treatments 1. The active ingredient can ABSTRACT","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68930019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}