Acta Cardiologica Sinica最新文献

{"title":"From Culture-Negative to PCR-Positive: Multimodality Imaging and Surgical Valve PCR in Diagnosing <i>Haemophilus Parainfluenzae</i> Mitral Valve Endocarditis.","authors":"Yi Ling Tan, Wenjie Huang, Shiun Woei Wong","doi":"10.6515/ACS.202601_42(1).20250923A","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250923A","url":null,"abstract":"","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"143-146"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Assessment of TAPSE/PASP Ratio and Its Correlation with Clinical Outcomes in Pulmonary Arterial Hypertension.","authors":"Tsung-Han Tsai, Wan-Jing Ho, Chun-Li Wang, Chia-Pin Lin, Fu-Chih Hsiao, Cze-Ci Chan, Chieh-Yu Chang","doi":"10.6515/ACS.202601_42(1).20250818F","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250818F","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to assess the prognostic significance of the longitudinal tricuspid annular plane systolic excursion (TAPSE) to pulmonary artery systolic pressure (PASP) ratio as a surrogate marker of right ventricular (RV) to pulmonary arterial (PA) coupling in patients with pulmonary arterial hypertension (PAH).</p><p><strong>Methods: </strong>A retrospective cohort study was conducted on patients with PAH. The TAPSE/PASP ratio at baseline and at 3 to 6 months of follow-up was evaluated along with other echocardiographic and clinical parameters.</p><p><strong>Results: </strong>The study included 68 patients with PAH, 75% of whom were female, with a mean age of 46 years and a mean follow-up duration of 64 months. At baseline, non-survivors had higher brain natriuretic peptide levels, shorter 6-minute walk distance (6MWD), and worse hemodynamic profiles compared with survivors. A TAPSE/PASP ratio > 0.22 mm/mmHg at baseline and > 0.23 mm/mmHg at 3 to 6 months of follow-up was associated with improved survival. Compared with baseline, survivors had lower pulmonary vascular resistance, lower PASP, and reduced left ventricular eccentricity indexat follow-up. In addition, better outcomes were observed in patients with World Health Organization functional class (WHO FC) I/II and 6MWD > 390 m compared with those in WHO FC III/IV and 6MWD ≤ 390 m.</p><p><strong>Conclusions: </strong>The TAPSE/PASP ratio is a noninvasive marker of RV-PA coupling that can provide dynamic prognostic insights in patients with PAH. It may assist in guiding treatment escalation and individualized therapy. Further studies are needed to verify its role and integration into comprehensive PAH risk assessment frameworks.</p>","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"22-32"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early-Phase Exercise-Based Comprehensive Cardiac Rehabilitation Program after Myocardial Infarction: A Randomized Controlled Trial.","authors":"Özge Ocaker Aktan, Sevgi Özalevli, Hüseyin Dursun, Ahmet Anıl Başkurt, Aylin Özgen Alpaydın, Dayimi Kaya","doi":"10.6515/ACS.202601_42(1).20250714D","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250714D","url":null,"abstract":"<p><strong>Background: </strong>Myocardial infarction (MI) remains a leading cause of mortality and morbidity worldwide. Cardiac rehabilitation (CR) is an evidence-based intervention that improves cardiovascular outcomes; however, the optimal timing and contents of CR remain unclear.</p><p><strong>Objectives: </strong>This study aimed to investigate the effects of an early-phase, exercise-based supervised comprehensive CR program on functional exercise capacity, grip strength, fatigue, sleep quality, and health-related quality of life (HRQOL) in patients with MI.</p><p><strong>Methods: </strong>A randomized controlled trial was conducted involving 32 medically stable MI patients allocated to either an intervention or control group. The intervention group received a two-phase supervised CR program initiated within the first week post-MI, including inpatient and outpatient aerobic, calisthenic, and strengthening exercises for eight weeks. The control group received usual care. Primary and secondary outcomes included the 6-minute walk distance (6MWD), 30-second sit-to-stand test (30-sec STS), grip strength, fatigue (functional assessment of chronic illness therapy [FACIT]-fatigue), sleep quality (Pittsburgh Sleep Quality Index [PSQI]), and HRQOL (12-Item Short-Form Questionnaire and MacNew Heart Disease Health-Related Quality of Life Questionnaire).</p><p><strong>Results: </strong>Compared to the control group, the intervention group showed significant improvements in 6MWD (mean difference [MD] = 97.3 m, p < 0.001), 30-sec STS (MD = 3.1 repetitions, p = 0.001), grip strength (MD = 5.7 kg, p = 0.04), FACIT-Fatigue score (MD = 8.8 points, p < 0.001), PSQI score (MD = -2.7 points, p < 0.001), and HRQOL subdomains (p < 0.05). No adverse events were reported.</p><p><strong>Conclusions: </strong>Early-phase supervised CR significantly enhanced physical capacity, fatigue, sleep quality, and HRQOL in this cohort of MI patients. Early initiation of structured CR should be considered in clinical practice to promote faster recovery and improve long-term outcomes following MI.</p>","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"33-46"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Outcomes in COVID-19 Patients Treated with Paxlovid: A Multicenter Retrospective Study.","authors":"Wei-Lun Chen, Victor Chien-Chia Wu, Chun-Li Wang, Yu-Ching Wang, Yu-Tung Huang, Chien-Hao Huang, Chih-Hsiang Chang, Shao-Wei Chen, Shang-Hung Chang, Cheng-Hsun Chiu, Pao-Hsien Chu","doi":"10.6515/ACS.202601_42(1).20250726A","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250726A","url":null,"abstract":"<p><strong>Background: </strong>The Coronavirus disease 2019 (COVID-19) pandemic necessitated rapid advances in treatment, with Paxlovid emerging as an effective oral antiviral. Despite its efficacy in reducing hospitalizations and mortality among high-risk patients, the impact of Paxlovid on cardiovascular outcomes remains unclear, especially given the increased cardiovascular risks associated with COVID-19.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study using data from the Chang Gung Memorial Hospital System in Taiwan of patients admitted with COVID-19 from January 1, 2022 to December 31, 2022. Propensity score matching was used to create comparable cohorts of patients treated with Paxlovid and those not treated with Paxlovid. The primary outcomes were cardiovascular events and all-cause mortality within a 12-month follow-up period.</p><p><strong>Results: </strong>The study analyzed 606 patients treated with Paxlovid and 1,809 matched patients who were not. Paxlovid significantly reduced all-cause mortality at 3 months (relative risk [RR] 0.75, p = 0.0216) and 6 months (RR 0.81, p = 0.0492), but this effect was not sustained at 12 months (p = 0.2069). Notably, venous thromboembolism rates were significantly higher in the Paxlovid group at 6 months (RR 4.78, p = 0.0057) and 12 months (RR 2.65, p = 0.0477).</p><p><strong>Conclusions: </strong>While Paxlovid treatment resulted in significant short-term survival improvements among COVID-19 patients, it was also associated with a higher incidence of venous thromboembolic complications. These findings highlight the need for careful patient selection and monitoring, particularly for those with preexisting cardiovascular conditions.</p>","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"87-98"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy of Ticagrelor and Clopidogrel in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention: A Cardiac Magnetic Resonance Imaging-Based Pilot Study.","authors":"Wei-Ting Wang, Chiu-Yang Lee, Shao-Sung Huang, Po-Hsun Huang, Pai-Feng Hsu, Hsin-Bang Leu, Tse-Min Lu, Shih-Hwa Chiou, Chin-Tien Wang, Tao-Cheng Wu","doi":"10.6515/ACS.202601_42(1).20251008A","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20251008A","url":null,"abstract":"<p><strong>Background: </strong>Ticagrelor provides faster and more consistent platelet inhibition than clopidogrel; however, its effect on myocardial injury during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) remains uncertain.</p><p><strong>Objectives: </strong>The aim of this pilot study was to assess the feasibility and preliminary effects of ticagrelor versus clopidogrel loading on myocardial injury in STEMI patients undergoing PCI, using cardiac magnetic resonance (CMR) imaging.</p><p><strong>Methods: </strong>Thirty STEMI patients were randomized to receive aspirin with either clopidogrel (300 mg) or ticagrelor (180 mg) before PCI, followed by standard maintenance therapy. Myocardial injury was evaluated 4-10 days post-PCI using CMR parameters (infarct size, myocardial salvage index [MSI], microvascular obstruction [MVO], and infarct transmurality). Enzymatic infarct size and 5-year clinical outcomes were also analyzed.</p><p><strong>Results: </strong>No significant differences in infarct size, MSI, MVO, or other CMR parameters were detected between the two groups. Left ventricular volume and function were comparable, with no major adverse cardiovascular events, stent thrombosis, or major bleeding over the 5-year follow-up period.</p><p><strong>Conclusions: </strong>Ticagrelor and clopidogrel showed similar effects on CMR-based myocardial injury and long-term outcomes in STEMI patients undergoing PCI. These pilot findings are hypothesis-generating and support the feasibility and inform sample-size planning for future multicenter trials.</p>","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"119-127"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exosomal MicroRNA-1 Regulate Cx43 Expression via Tbx18 in Culture Atrial Fibroblasts under Rapid Electrical Stimulation.","authors":"Cheng-Yen Chuang, Bao-Wei Wang, Ying-Ju Yu, Wei-Jen Fang, Chiu-Mei Lin, Kou-Gi Shyu, Su-Kiat Chua","doi":"10.6515/ACS.202601_42(1).20250819A","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250819A","url":null,"abstract":"<p><strong>Background: </strong>MicroRNAs (miRs) are involved in cardiac remodeling, and tachyarrhythmia can regulate miR expression. While microRNA-1 (miR-1) is essential for genes involved in atrial tachyarrhythmia, the effect of rapid electrical stimulation (RES) on fibroblast-derived exosomal miR-1 is unknown. This study investigated the molecular regulation of exosomal miR-1 and its therapeutic potential in human atrial fibroblasts (HCF-aa) using RES.</p><p><strong>Methods: </strong>HCF-aa were cultured in a pacer dish and exposed to RES (0.5 V/cm and 10 Hz). We then investigated whether miR-1 expression could be regulated in HCF-aa under RES, and examined the effects on T-box transcription factor 18 (Tbx18) and connexin 43 (Cx43) protein levels.</p><p><strong>Results: </strong>RES initially upregulated and subsequently downregulated exosomal miR-1 expression. Overexpression of miR-1 reduced Tbx18 levels but increased Cx43 expression in HCF-aa after 64 hours of RES. Conversely, mutant miR-1 and miR-1 antagomir significantly reduced Cx43 expression. Luciferase reporter assays indicated that miR-1 antagomir pretreatment suppressed the transcriptional activity of Tbx18 on the Cx43 promoter, an effect reversed by mutating the Tbx18 binding site. RES for 24 hours increased exosomal miR-1 and led to a reduction in Tbx18 3'-UTR luciferase activity; this effect was mitigated by mutating the hsa-miR-1-3p binding site. Immunohistochemical staining confirmed that miR-1 antagomir downregulated Cx43, while Tbx18 siRNA upregulated Cx43 in RES-exposed HCF-aa.</p><p><strong>Conclusions: </strong>In HCF-aa under RES, miR-1 and Tbx18 regulated Cx43 expression, with miR-1 modulating Cx43 through Tbx18. These findings provide insights into the molecular mechanisms of cardiac remodeling and offer potential therapeutic targets for treating tachyarrhythmia.</p>","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"47-61"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Septic Coronary Embolism Causing ST-Elevation Myocardial Infarction: A Rare and Life-Threatening Complication of Infective Endocarditis.","authors":"Pei-Jung Chen, Wei-Chung Tsai, Po-Chao Hsu, Tsung-Hsien Lin, Tzu-Chieh Lin","doi":"10.6515/ACS.202601_42(1).20250922A","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250922A","url":null,"abstract":"","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"132-135"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Caseous Calcification of the Mitral Annulus Mimicking an Intracardiac Cystic Tumor: A Report of Two Cases.","authors":"Yueh-Fang Lai, Shih-Rong Hsieh","doi":"10.6515/ACS.202601_42(1).20251027A","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20251027A","url":null,"abstract":"","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"136-138"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835867/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Undersized Versus Conventional Covered Stent Sizing for Hemodialysis Access-Related Central Venous Occlusive Disease: A Retrospective Cohort Study.","authors":"John Chien-Hwa Chang, Shih-Ming Huang, Honda Hsu, Yi-Tso Cheng, Ing-Heng Hii, Chi-Fu Cheng, Pei-Chei Lu","doi":"10.6515/ACS.202601_42(1).20250818E","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250818E","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare access and target lesion patency rates between undersized and apposed/oversized lateral-edge covered stents in patients with hemodialysis access-related central venous occlusive disease (CVOD).</p><p><strong>Methods: </strong>A retrospective analysis of 76 hemodialysis patients undergoing endovascular treatment for CVOD was conducted. All of the patients received undersized covered stents at the medial edge. Based on lateral-edge sizing, the patients were divided into undersized (n = 14) and apposed/oversized (n = 62) groups. Patency outcomes were compared using the log-rank test, and multivariable analysis was used to identify risk factors associated with the primary outcome.</p><p><strong>Results: </strong>The 12-month access primary patency rate was significantly higher in the undersized group than in the apposed/oversized group (76.4% vs. 25.9%, p = 0.047). The 12-month target lesion primary patency rate was also higher in the undersized group; however, the difference was not statistically significant (76.4% vs. 52.1%, p = 0.186). Factors associated with the primary outcome included older age (odds ratio [OR] = 1.03, p = 0.011), coronary artery disease (OR = 2.03, p = 0.041), stenting to central veins for access thrombosis (OR = 3.53, p = 0.001), more stents (OR = 3.11, p = 0.002), apposed/oversized lateral stent edge (OR = 2.73, p = 0.044), and higher stent-to-vessel ratio (OR = 1.19, p = 0.022).</p><p><strong>Conclusions: </strong>The 12-month primary patency rate was better in the undersized group than in the apposed/oversized group. Endovascular treatment with undersized covered stents may be a feasible approach for hemodialysis access-related CVOD. Larger randomized studies are required to confirm these findings.</p>","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"99-110"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitigating Transseptal Puncture Complications by Guiding with an Angioplasty Wire and an Electrified Brockenbrough Stylet.","authors":"Chi-Tung Chen, Wan-Jung Chang, Chiung-Ray Lu, Wen-Pin Hu, Yen-Nien Lin, Kuan-Cheng Chang, Wei-Hsin Chung","doi":"10.6515/ACS.202601_42(1).20250718A","DOIUrl":"https://doi.org/10.6515/ACS.202601_42(1).20250718A","url":null,"abstract":"<p><strong>Background: </strong>Transeptal puncture (TSP) is an important technique in catheter ablation and structural interventions. Several novel techniques and equipment have been developed, however they are limited by availability and cost.</p><p><strong>Objective: </strong>To evaluate the efficacy and safety of a modified TSP technique guided by a 0.014″ angioplasty wire and an electrified Brockenbrough (BRK) stylet.</p><p><strong>Methods: </strong>One hundred consecutive patients who received the modified TSP technique and another 100 undergoing conventional TSP for pulmonary vein isolation for non-valvular atrial fibrillation from January 2019 to January 2023 were retrospectively analyzed. A historical comparison with three associated studies was performed. Age, gender, left atrial diameter, left ventricular ejection fraction, acute complications, and BRK needle jump distances during TSP were analyzed.</p><p><strong>Results: </strong>Both groups demonstrated comparable characteristics, including age (conventional TSP vs. modified TSP; 65.8 ± 9.6 vs. 63.63 ± 10.3 years; p = 0.077), sex (conventional TSP vs. modified TSP; males, 75% vs. 67%; p = 0.213), and left atrial diameter (conventional TSP vs. modified TSP; 40.55 ± 7.7 vs. 42.60 ± 8.2 mm; p = 0.069). All received continuous periprocedural nonvitamin K oral anticoagulants and underwent TSP with a BRK needle. There was no acute pericardial effusion or tamponade immediately after TSP or at the end of catheter ablation. Inadvertent jump of the BRK needle was significantly attenuated in the modified TSP group (conventional TSP vs. modified TSP; 0.766 ± 0.19 vs. 1.455 ± 0.48 cm; p < 0.001). No TSP-related complications were observed.</p><p><strong>Conclusions: </strong>The modified TSP technique using readily available equipment with an electrified stylet and a 0.014″ angioplasty wire is a simple, safe, and cost-effective alternative. This method reduces the built-up tension by mechanical force during tenting and minimizes the risk of inadvertent jumping.</p>","PeriodicalId":6957,"journal":{"name":"Acta Cardiologica Sinica","volume":"42 1","pages":"14-21"},"PeriodicalIF":1.8,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12835868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146091671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}