Acta pathologica et microbiologica Scandinavica. Section A, Pathology最新文献

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Autolytic changes in the human myocardium. Particularly with a view to detecting acute myocardial infarction by the Nitro-BT method. 人心肌的自溶变化。特别针对硝基bt法检测急性心肌梗死。
Acta pathologica et microbiologica Scandinavica. Section A, Pathology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB03859.X
J. A. Andersen, B. Hansen
{"title":"Autolytic changes in the human myocardium. Particularly with a view to detecting acute myocardial infarction by the Nitro-BT method.","authors":"J. A. Andersen, B. Hansen","doi":"10.1111/J.1699-0463.1974.TB03859.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB03859.X","url":null,"abstract":"Very few studies are available on autolytic changes in the human myocardium. We therefore made a study of 30 hearts maintained in situ. Fifteen hearts were studied on an average 91/2 hours postmortem, and the other 15 hearts on an average 74 hours postmortem. Two myocardial slices from each heart were incubated for 30 minutes at 37°C in a solution consisting of substrate, Nitro-BT and buffer. Twenty-five hearts were intensely and uniformly blackish blue in appearance, due to the formation of diformazan in the myocardium, whereas five hearts presented unstained areas. These areas were evaluated as being recent myocardial infarcts. Micro-enzymatic studies of the same hearts revealed corresponding results. With increasing postmortem intervals, the diformazan appeared as coarse, uneven and disarranged granules. With regard to the commonly accepted parameters pertaining to recent myocardial infarct, histological study showed these parameters to vary so much from one heart to another and from one area to another within the individual heart that we abandoned quantitative analysis of these changes. The macro- and micro-enzymatic dehydrogenase reaction is well-suited for the detection of acute myocardial infarction in all cases up to and including the third postmortem day.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"45 1","pages":"337-44"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84430504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Transthoracic aspiration biopsy. A study on diagnostic reproducibility. 经胸穿刺活检。诊断可重复性的研究。
Acta pathologica et microbiologica Scandinavica. Section A, Pathology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1977.TB03905.X
D. Francis, K. Højgaard
{"title":"Transthoracic aspiration biopsy. A study on diagnostic reproducibility.","authors":"D. Francis, K. Højgaard","doi":"10.1111/J.1699-0463.1977.TB03905.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1977.TB03905.X","url":null,"abstract":"Based on a randomized material of 100 histologically verified transthoracic aspiration biopsies an inter- and intraobserver variation study was carried out by the two investigators. The results showed a high degree of diagnostic reproducibility pointing towards the value of the aspiration biopsy per se. It is concluded that this diagnostic method is reliable in the hands of the expert and useful even in the hands of a pathologist only given a short introduction to--and a reasonable amount of correction within--this special field.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"602 1","pages":"889-96"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77088201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Cause of increased plasma angiotensinogen after nephrectomy. The renin-system in normal, renal hypertensive and DOCA + salt treated rats after unilateral or bilateral nephrectomy or shamoperation. 肾切除术后血浆血管紧张素原增高的原因。单侧或双侧肾切除或手术后正常大鼠、肾高血压大鼠和DOCA +盐处理大鼠肾素系统的变化。
Acta pathologica et microbiologica Scandinavica. Section A, Pathology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1970.TB03519.X
J. Bing, K. Poulsen
{"title":"Cause of increased plasma angiotensinogen after nephrectomy. The renin-system in normal, renal hypertensive and DOCA + salt treated rats after unilateral or bilateral nephrectomy or shamoperation.","authors":"J. Bing, K. Poulsen","doi":"10.1111/J.1699-0463.1970.TB03519.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1970.TB03519.X","url":null,"abstract":"24 hours after nephrectomy there is an increase in plasma angiotensinogen which is 2 to 3 times increased in unilaterally nephrectomized rats and 5 to 12 times increased in bilaterally nephrectomized rats. In normal rats, DOCA + salt treated rats and renal hypertensive rats, the postnephrectomy changes are about the same, independent of the marked differences in their pre-operative plasma and renal renin. The postnephrectomy increase in angiotensinogen must therefore be due to loss of some internal factor other than renin or to loss of some external renal function. Both shamoperation and unilateral nephrectomy are followed by a marked decrease in plasma renin, the postoperative fall being more pronounced after removal of a clamped kidney than after removal of a normal.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"85 1","pages":"669-73"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83286735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
MULTIPLE EPIPHYSEAL DYSPLASIA. 多发性骨骺发育不良。
Acta pathologica et microbiologica Scandinavica. Section A, Pathology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1975.TB00160.X
P. Rasmussen
{"title":"MULTIPLE EPIPHYSEAL DYSPLASIA.","authors":"P. Rasmussen","doi":"10.1111/J.1699-0463.1975.TB00160.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1975.TB00160.X","url":null,"abstract":"The cartilage of epiphysis and cuboid bones from three Beagle puppies bred from parents with a constant heredity of multiple epiphyseal dysplasia, was examined macroscopically, histo-morphologically and histochemically. The puppies were euthanized at the age of one week, three weeks and five weeks, respectively. The investigation showed that foci of the disease develop in a broad subarticular zone where normally strong three-dimensional growth of the cartilage takes place. The first signs of the disease appeared about the time of birth and new foci reached a climax when the puppies were about three weeks old. Histomorphological and histochemical examination of the cartilage showed that the disease developed in a sequence of confluent stages. In the initial stage, there was an accumulation of abnormal cartilage matrix in the chondrocyte and/or chondrocyte lacunae. The abnormal substance consisted apparently of concentrated or free chondroitin sulphates not bound to protein. Then followed a second stage of liquefaction and coalescence of the abnormal cartilage matrix which formed cysts of different sizes, some of them visible macroscopically. In the third stage of calcification of the cyst content and surrounding abnormal cartilage, it was found that the calcium was deposited in grains bound to chondroitin sulphates. The results of the present study of the pre-calcification stage of the disease in Beagle dogs seem to be comparable with or equivalent to the results of the study of the post-natal stage of the disease in children and may explain something of the prenatal pathogenesis in children.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"50 1","pages":"493-502"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87980120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Extracorporeal irradiation of the blood. Histological examinations of homografts in patients undergoing immunosuppressive therapy with ECIB before kidney transplantation. 血液的体外照射同种移植物在肾移植前接受ECIB免疫抑制治疗的组织学检查。
Acta pathologica et microbiologica Scandinavica. Section A, Pathology Pub Date : 2009-08-15 DOI: 10.1111/J.1699-0463.1974.TB00364.X
E. Weeke, B. Henriksen
{"title":"Extracorporeal irradiation of the blood. Histological examinations of homografts in patients undergoing immunosuppressive therapy with ECIB before kidney transplantation.","authors":"E. Weeke, B. Henriksen","doi":"10.1111/J.1699-0463.1974.TB00364.X","DOIUrl":"https://doi.org/10.1111/J.1699-0463.1974.TB00364.X","url":null,"abstract":"By means of extracorporeal irradiation of the blood (ECIB) lymphopenia is produced in man. This method has been used in the clinical work as immunosuppressive therapy before and after renal transplantation. In the present study, the histological changes of acute and chronic rejection in non-surviving kidney grafts were compared in 29 patients who received ECIB before and after grafting (group I) and 42 non-ECIB treated patients (group II). The median survival time of the graft was 45 days (range 2–790). In addition, the histological changes in biopsies from the grafts taken during early acute rejection episodes were studied. The histological changes were divided in acute rejection and chronic changes and graded according to the severity of the observed changes. Furthermore, the degree of mononuclear cell infiltration were evaluated. No statistical difference between group I and II, neither regarding histological changes in the grafted kidneys nor in the biopsies, could be demonstrated.","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"29 1","pages":"389-96"},"PeriodicalIF":0.0,"publicationDate":"2009-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89399188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Massive pulmonary deposition of rutile after titanium dioxide exposure: Light-microscopical and physico-analytical methods in pigment identification. 二氧化钛暴露后金红石的大量肺沉积:颜料鉴定中的光学显微镜和物理分析方法。
L E Rode, E M Ophus, B Gylseth
{"title":"Massive pulmonary deposition of rutile after titanium dioxide exposure: Light-microscopical and physico-analytical methods in pigment identification.","authors":"L E Rode,&nbsp;E M Ophus,&nbsp;B Gylseth","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autopsy findings in a 55-year old man known to have been occupationally heavily exposed to titanium dioxide dust showed extensive pulmonary deposition of white pigment. By energy dispersive X-ray analysis (EDAX) and electron and X-ray diffraction, the pigment was identified as rutile. By ordinary transmitted light microscopy, deposits of the white crystalline titanium-dioxide could not be distinguished from anthracotic pigment present in the lung sections. By transmitted polarized and incident light microscopy, the different nature of the two types of pigment was immediately evident. Absence of inflammatory and fibrotic changes in the lungs in our case lends support to the view that rutile is biochemically inert.</p>","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"89 6","pages":"455-61"},"PeriodicalIF":0.0,"publicationDate":"1981-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18346468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Receptors for the lectins wheat germ. Ricinus communis I and soybean in ameloblastomas and normal oral mucosa. 小麦胚芽凝集素的受体。小麦胚芽凝集素 I 和大豆凝集素在釉母细胞瘤和正常口腔粘膜中的受体。
P Vedtofte, E Dabelsteen
{"title":"Receptors for the lectins wheat germ. Ricinus communis I and soybean in ameloblastomas and normal oral mucosa.","authors":"P Vedtofte, E Dabelsteen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The histological distribution of receptors for the lectins Wheat germ (WGA). Ricinus communis I (RCA I) and Soybean (SBA) was examined in ameloblastomas and normal oral mucosa from 12 patients. The study utilized fluorescein-conjugated WGA, RCA I and SBA. Cell-membrane bound receptors for these 3 lectins were demonstrated in the spinous cell layer of the normal oral mucosa. WGA and RCA I receptors were also located in the basal cell layer, whereas SBA receptors were not detectable there. Cell-membrane bound WGA receptors were shown in the epithelial cells of the ameloblastomas. Titrations showed significant differences in staining reactivity related to the morphology of the peripheral epithelial cells of the ameloblastomas. The distribution of RCA I and SBA receptors in the peripheral cells was also related to the morphology of these cells and was independent of the histological types of the tumours. It is suggested that the distribution of these receptors is related to cellular activities such as cell differentiation and cell migration in the tumour and therefore possibly reflects the biological behavior of the tumours.</p>","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"89 6","pages":"439-49"},"PeriodicalIF":0.0,"publicationDate":"1981-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18215151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumours in Iceland. 3. Malignant tumours of kidney. A histological classification. 冰岛的肿瘤。肾恶性肿瘤。组织学分类
P Thorhallsson, H Tulinius
{"title":"Tumours in Iceland. 3. Malignant tumours of kidney. A histological classification.","authors":"P Thorhallsson,&nbsp;H Tulinius","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Malignant tumours of the kidney occurring in Iceland during the year 1955-1974 were studied pathologically and typed histologically according to a classification proposed, but not yet published, by the World Health Organisation. Histological material was available from 89.2% and 84.0% of registered male and female patients respectively. Among males, renal cell carcinomas constituted 91.8%, transitional pelvic carcinomas 5.5% and nephroblastomas 2.7% of classified tumours. The corresponding figures for females were renal cell carcinomas 96.7%, transitional pelvic carcinomas 0.8%, and nephroblastomas 2.5%. The most frequent cell type of renal cell carcinoma group in both sexes was the combination of clear and granular cells, and the most frequent architecture was the combination of solid and tubular patterns. Renal cell carcinomas composed of pure granular cells were found in 22% of males and in 14% of females, and granular cells in combinations with all other cell types were also more common in males. In Iceland renal cell carcinoma is the fifth commonest malignant tumour in males and the tenth in females. The excess of granular cell tumours among males corresponds roughly to, and may account for, the sex difference in the frequency of renal cell carcinomas.</p>","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"89 5","pages":"403-10"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18325807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumours in Iceland. 4. Tumours of the upper respiratory tract and ear. A histological classification and some etiological and epidemiological considerations. 冰岛的肿瘤。上呼吸道和耳朵的肿瘤。组织学分类和一些病原学和流行病学方面的考虑。
M A Cooper, J Hallgrímsson
{"title":"Tumours in Iceland. 4. Tumours of the upper respiratory tract and ear. A histological classification and some etiological and epidemiological considerations.","authors":"M A Cooper,&nbsp;J Hallgrímsson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>All primary tumours from the upper respiratory tract and ear submitted for a histological diagnosis in Iceland during the 20 years, 1955-1974, were reviewed and typed according to the World Health Organization Classification published in 1978. The series included 83 benign and 114 malignant tumours from the upper respiratory tract. The nasal cavity was the commonest site for benign tumours in both sexes, most being squamous cell and transitional papillomas. The larynx was the commonest site for malignant tumours in males, all being squamous cell carcinomas, and the paranasal sinuses and the nasopharynx in females, squamous cell carcinoma forming the largest group in the sinuses and undifferentiated carcinoma in the nasopharynx. The distribution of tumours in the nasal cavity and sinuses differed much between the two sites and between the sexes, which emphasizes that these two sites should be separated and not combined as they have been until recently in epidemiological reports and cancer registries. A relatively high incidence of nasopharyngeal carcinoma in Iceland may be due to a high consumption of salted food. A rising incidence of laryngeal carcinoma is believed to be related to the use of tobacco and alcohol and is of special concern owing to its marked rise in young females.</p>","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"89 5","pages":"377-87"},"PeriodicalIF":0.0,"publicationDate":"1981-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18327053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Angiolymphoid hyperplasia with eosinophilia of the skin. Light microscopic and ultrastructural study of 4 cases. 血管淋巴样增生伴皮肤嗜酸性粒细胞增多。4例的光镜及超微结构研究。
L G Kindblom, A S Fassina
{"title":"Angiolymphoid hyperplasia with eosinophilia of the skin. Light microscopic and ultrastructural study of 4 cases.","authors":"L G Kindblom,&nbsp;A S Fassina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A clinical, light and electron microscopic study of four patients with angiolymphoid hyperplasia with eosinophilia of the skin is presented. Light-microscopically, the lesions were characterized by the small size and superficial location, the proliferation of mostly delicate vessels with prominent endothelial hyperplasia and cellular areas without distinct vessel structures, but with infiltrates of eosinophilic leukocytes, lymphocytes and plasma cells. Ultrastructurally, a marked proliferation of both endothelial cells and pericytes could be demonstrated and the solid cellular areas were shown to be composed of solid vascular buds. A multi-layered basal lamina was enclosing pericytes and external surfaces of endothelial cells. The differential diagnosis is discussed and it is emphasized that this lesion may be misinterpreted as angiosarcoma.</p>","PeriodicalId":6953,"journal":{"name":"Acta pathologica et microbiologica Scandinavica. Section A, Pathology","volume":"89 4","pages":"271-83"},"PeriodicalIF":0.0,"publicationDate":"1981-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18328099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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