Acta dermato-venereologica最新文献_第9页

Patient Perspectives, Unmet Needs and Dilemmas in Reproductive Decision-making for Genodermatoses: A Qualitative Interview Study. 患者的观点，未满足的需求和困境在生殖决策的遗传性皮肤病：一项定性访谈研究。

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-10 DOI: 10.2340/actadv.v106.adv-2025-0278

Fauve C A P Van Veen, Otte J M Borghouts, Julia M K Clabbers, Peter M Steijlen, Karin Veldman, Femke Tammer, Michel Van Geel, Klara Mosterd, Liesbeth Van Osch, Malou Heijligers, Antoni H Gostyński

{"title":"Patient Perspectives, Unmet Needs and Dilemmas in Reproductive Decision-making for Genodermatoses: A Qualitative Interview Study.","authors":"Fauve C A P Van Veen, Otte J M Borghouts, Julia M K Clabbers, Peter M Steijlen, Karin Veldman, Femke Tammer, Michel Van Geel, Klara Mosterd, Liesbeth Van Osch, Malou Heijligers, Antoni H Gostyński","doi":"10.2340/actadv.v106.adv-2025-0278","DOIUrl":"10.2340/actadv.v106.adv-2025-0278","url":null,"abstract":"Impact on quality of life due to inherited skin diseases (also known as genodermatoses) may lead to reproductive dilemmas for affected couples or individuals considering parenthood. Currently, little is known about reproductive decision-making (RDM) for those affected by or at-risk of genodermatoses. Couples/individuals' perspectives with genodermatoses were qualitatively explored by focusing on (i) the impact of these diseases on the desire to have children, (ii) the knowledge of different reproductive options and personal considerations and, (iii) experiences with reproductive counselling. Semi-structured interviews were conducted with participants aged ≥16 years, diagnosed with a genodermatosis, and an active, (un)fulfilled or future desire to have children and analysed using a reflexive thematic content approach. Thirty participants were interviewed until saturation. Two main themes and 9 subthemes were identified. Participants preferred wanting to avoid passing on their genodermatosis to offspring, thereby complicating RDM. This preference was influenced by negative experiences with the disease, resulting in fear and uncertainty about severe manifestations in offspring. Positives and shortcomings in clinical practice were expressed, particularly the lack of reproductive counselling as a standard part of care. This study highlights the substantial impact of genodermatoses in RDM and the importance of routine reproductive counselling for those affected by or at-risk of genodermatoses.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253761/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148215717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bullous Pemphigoid Following IgG/IgA Pemphigus: Possible Involvement of SGLT2 and DPP-4 Inhibitors. IgG/IgA天疱疮后的大疱性类天疱疮：可能与SGLT2和DPP-4抑制剂有关。

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-10 DOI: 10.2340/actadv.v106.adv-2026-0507

Ayano Ikeda, Naomi Tani, Norito Ishii, Hiroshi Koga, Yuichi Yoshida

引用次数: 0

Joint Relationship of Cardiovascular-kidney-metabolic Syndrome and Psoriasis with All-cause and Cause-specific Mortality in Adults: A Population-based Analysis. 心血管-肾脏代谢综合征和牛皮癣与成人全因和特定原因死亡率的联合关系：一项基于人群的分析

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-10 DOI: 10.2340/actadv.v106.adv-2025-0241

Junhan Zhou, Hongping Ge, Bixin Huang, Yingwei Wang, Hongkai Xiang

{"title":"Joint Relationship of Cardiovascular-kidney-metabolic Syndrome and Psoriasis with All-cause and Cause-specific Mortality in Adults: A Population-based Analysis.","authors":"Junhan Zhou, Hongping Ge, Bixin Huang, Yingwei Wang, Hongkai Xiang","doi":"10.2340/actadv.v106.adv-2025-0241","DOIUrl":"10.2340/actadv.v106.adv-2025-0241","url":null,"abstract":"Psoriasis has been associated with cardiovascular risk, but the combined association of psoriasis and cardiovascular-kidney-metabolic (CKM) syndrome with mortality remains unclear. This study examined the individual and joint associations of CKM syndrome and self-reported psoriasis with allcause and cardio-cerebrovascular disease (CCD) mortality among 9,598 U.S. adults aged ≥20 years from NHANES 2003-2006 and 2009-2014. CKM syndrome stages were defined according to the 2023 American Heart Association framework, and psoriasis was assessed by self-reported physician diagnosis. Mortality was ascertained through linkage to the National Death Index through 2019. During a median follow-up of 9.3 years, 860 deaths occurred. Advanced CKM syndrome was associated with higher all-cause mortality (HR=3.67; 95% CI: 3.00-4.50) and CCD mortality (HR=8.16; 95% CI: 5.42-12.28). Psoriasis was also associated with higher all-cause mortality (HR=2.06; 95% CI: 1.47-2.90) and CCD mortality (HR=2.69; 95% CI: 1.42-5.08). Participants with both advanced CKM syndrome and psoriasis had the highest observed risks of all-cause mortality (HR=7.09; 95% CI: 4.93-10.19) and CCD mortality (HR=16.47; 95% CI: 7.26-37.33). Formal interaction testing did not show significant multi-plicative interaction for all-cause mortality (p for interaction=0.16) or CCD mortality (p for interaction=0.80). These findings suggest that coexisting advanced CKM syndrome and psoriasis may identify adults with particularly elevated mortality risk.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148215586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and Safety of Nemolizumab at Week 48: Results from the Maintenance Phase of Two Global Phase 3 Pivotal Studies (ARCADIA 1&2) in Patients with Moderate-to-Severe Atopic Dermatitis. Nemolizumab在48周的疗效和安全性：两项全球3期关键研究（ARCADIA 1&2）在中重度特应性皮炎患者中的维持期结果

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-10 DOI: 10.2340/actadv.v106.adv-2025-0085

Andreas Wollenberg, Jonathan I Silverberg, Franz J Legat, Marie Tauber, Vivian T Laquer, April W Armstrong, Andrew E Pink, Luigi Naldi, Grażyna Pulka, Jacek Zdybski, Athanasios Tsianakas, Jorge Diaz, Inese Svarca, Jennifer Beecker, Galina Balakirski, Sylvia Pauser, Liliana Ulianov, Anna Ryzhkova, Jean-Loup Machu, Christophe Piketty

{"title":"Efficacy and Safety of Nemolizumab at Week 48: Results from the Maintenance Phase of Two Global Phase 3 Pivotal Studies (ARCADIA 1&2) in Patients with Moderate-to-Severe Atopic Dermatitis.","authors":"Andreas Wollenberg, Jonathan I Silverberg, Franz J Legat, Marie Tauber, Vivian T Laquer, April W Armstrong, Andrew E Pink, Luigi Naldi, Grażyna Pulka, Jacek Zdybski, Athanasios Tsianakas, Jorge Diaz, Inese Svarca, Jennifer Beecker, Galina Balakirski, Sylvia Pauser, Liliana Ulianov, Anna Ryzhkova, Jean-Loup Machu, Christophe Piketty","doi":"10.2340/actadv.v106.adv-2025-0085","DOIUrl":"10.2340/actadv.v106.adv-2025-0085","url":null,"abstract":"Nemolizumab with background topical therapy (corticosteroids±calcineurin inhibitors) significantly improved skin lesions, itch and sleep in two global phase 3 trials (ARCADIA 1&2) in adolescents and adults with moderate-to-severe atopic dermatitis through week (W)16. Efficacy and safety of nemolizumab, combined with background topical therapy, were evaluated for an additional 32 weeks (W16-W48) with a focus on maintained skin responses in clinical responders (patients achieving Investigator's Global Assessment [IGA] score of 0/1 [clear/almost clear] or ≥75% improvement in Eczema Area and Severity Index [EASI-75] at W16). At W16, clinical responders (N=507) to nemolizumab every 4 weeks (Q4W) were rerandomized (1 : 1 : 1) to receive nemolizumab 30 mg-Q4W/-Q8W/placebo (nemolizumab-withdrawal) subcutaneously with background topical therapy. At W48, 61.5% (strata-adjusted difference versus nemolizumab-withdrawal group [Δ], 11.8% [95% CI 1.3-22.3]) and 76.3% (Δ, 12.4% [95% CI 2.7- 22.0]) of patients in nemolizumab-Q4W; 60.4% (Δ, 10.7% [95% CI 0.3-21.0]) and 75.7% (Δ, 11.8% [95% CI 2.1-21.5]) in nemolizumab-Q8W; and 49.7% and 63.9% in nemolizumab-withdrawal group maintained response rate for IGA success and EASI-75, respectively. The percentage of patients who experienced ≥1 adverse events were similar across the groups (range: 53.5%-58.3%). Up to W48, skin responses were maintained without notable differences in the safety profile of both nemolizumab dosing regimens.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148215542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Skin Dryness and Disease-related Parameters with Mechanical Alloknesis in Atopic Dermatitis: A Crosssectional and Prospective Cohort Study. 皮肤干燥和疾病相关参数与特应性皮炎机械异位的关联：一项横断面和前瞻性队列研究。

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-10 DOI: 10.2340/actadv.v106.adv-2025-0246

Masaru Uto, Eriko Komiya, Go Kojima, Yayoi Kamata, Sumika Toyama, Kotaro Honda, Takahide Kaneko, Yasushi Suga, Mitsutoshi Tominaga, Kenji Takamori

{"title":"Association of Skin Dryness and Disease-related Parameters with Mechanical Alloknesis in Atopic Dermatitis: A Crosssectional and Prospective Cohort Study.","authors":"Masaru Uto, Eriko Komiya, Go Kojima, Yayoi Kamata, Sumika Toyama, Kotaro Honda, Takahide Kaneko, Yasushi Suga, Mitsutoshi Tominaga, Kenji Takamori","doi":"10.2340/actadv.v106.adv-2025-0246","DOIUrl":"10.2340/actadv.v106.adv-2025-0246","url":null,"abstract":"Mechanical alloknesis (MA), namely itch hypersensitivity evoked by normally innocuous mechanical stimuli, may exacerbate the itch-scratch cycle in atopic dermatitis (AD). Although various molecular and neural pathways have been identified in animal models, the clinical mechanisms underlying MAmechanical alloknesis remain unclear, particularly in relation to disease severity and biomarkers. We hypothesized that AD atopic dermatitis severity-related parameters are associated with MAmechanical alloknesis. To investigate this, we performed a cross-sectional study comparing healthy controls and ADatopic dermatitis patients, and a prospective cohort study evaluating ADatopic dermatitis patients receiving dupilumab. In the cross-sectional study, MAmechanical alloknesis scores were significantly higher in lesional than in non-lesional or healthy skin. Skin dryness parameters (transepidermal water loss and stratum corneum hydration) showed no significant correlation with MAmechanical alloknesis. Among serum biomarkers, only thymus and activation-regulated chemokine (TARC) levels showed a moderate positive correlation with MAmechanical alloknesis but not with spontaneous itch. In the prospective study, dupilumab significantly reduced eosinophil counts, IgE, TARC, spontaneous itch, and MAmechanical alloknesis scores, although TARC remained correlated with MAmechanical alloknesis after treatment. These findings suggest that TARC may be involved in the induction of MAmechanical alloknesis and represent a potential biomarker or therapeutic target for MAmechanical alloknesis in ADatopic dermatitis.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13253756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148215897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prior Specific Biologic Use as a Potential Risk Factor for Administration-related Reactions to Ixekizumab after Excipient Modification: A Single-centre Retrospective Study. 先前的特定生物使用是辅料修改后伊谢珠单抗给药相关反应的潜在危险因素：一项单中心回顾性研究

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-08 DOI: 10.2340/actadv.v106.adv-2026-0461

Hiroyoshi Nozaki, Masaru Honma, Yasuyuki Fujita

引用次数: 0

Glucagon-Like Peptide-1 Receptor Agonists as a Potential Mitochondrial Modulation Therapy for Hidradenitis Suppurativa. 胰高血糖素样肽-1受体激动剂作为化脓性汗腺炎潜在的线粒体调节疗法。

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-08 DOI: 10.2340/actadv.v106.adv-2025-0093

Aref Hosseini, Stephan Von Gunten, Robert E Hunger, Christos C Zouboulis, S Morteza Seyed Jafari

引用次数: 0

Long-term Recurrence after Curettage ± Electrodesiccation for Basal Cell Carcinoma: A Nationwide Cohort Study of 47,358 Tumours from Dermatology Practices. 刮除±电干燥治疗基底细胞癌后长期复发：一项来自皮肤科实践的47358例肿瘤的全国队列研究。

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-02 DOI: 10.2340/actadv.v106.adv-2025-0079

Emilie W Kjeldsen, Susanne K Kjær, Johan Sieborg, Henrik Sølvsten, Merete Hædersdal

{"title":"Long-term Recurrence after Curettage ± Electrodesiccation for Basal Cell Carcinoma: A Nationwide Cohort Study of 47,358 Tumours from Dermatology Practices.","authors":"Emilie W Kjeldsen, Susanne K Kjær, Johan Sieborg, Henrik Sølvsten, Merete Hædersdal","doi":"10.2340/actadv.v106.adv-2025-0079","DOIUrl":"10.2340/actadv.v106.adv-2025-0079","url":null,"abstract":"The incidence of basal cell carcinoma is increasing globally, with Denmark showing a 220% rise between 2013 and 2021, underscoring the need to optimize treatment strategies. Curettage with or without electrodesiccation (C±E) is commonly used, yet updated tumour-specific recurrence data are limited. Using the Danish Skin Cancer Registry, we assessed long-term recurrence after C±E for 47,358 basal cell carcinomas treated in office-based dermatological practices between 2013 and 2022. Follow-up began one year after treatment, and recurrence was evaluated using Kaplan-Meier analysis and Cox regression to estimate cumulative recurrence rates and hazard ratios (HR) by tumour characteristics. The 5-year recurrence rate was 9.9% (95% CI 9.4-10.3), increasing to 13.3% (12.6-14.1) at 8 years. Head and neck tumours had the highest recurrence (25.1% at 8 years; HR 2.25, 2.00-2.53), as did tumours >10 mm (16.7% at 8 years; HR 1.80, 1.62-1.99), while superficial basal cell carcinomas had the lowest recurrence (8.4% at 8 years; HR 0.46, 0.38-0.56). Incomplete follow-up may have introduced bias in recurrence estimates. This nationwide study, the largest to date with up to 8 years of follow-up, shows that C±E remains a viable treatment, but careful tumour selection is essential to optimize long-term outcomes.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13230343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148147782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between Dermatology Life Quality Index Scores and EQ-5D-5L Utility Values in Adults with Atopic Dermatitis: Development of a Swedish Mapping Model. 成人特应性皮炎患者皮肤科生活质量指数评分与EQ-5D-5L效用值的关系：瑞典绘图模型的发展

IF 3.8 4区医学

Acta dermato-venereologica Pub Date : 2026-06-02 DOI: 10.2340/actadv.v106.adv-2025-0277

Alexandra Metsini, Linda Ryen, Scott Montgomery, Anu Molarius, Åke Svensson, Laura Kobyletzki

{"title":"Relationship between Dermatology Life Quality Index Scores and EQ-5D-5L Utility Values in Adults with Atopic Dermatitis: Development of a Swedish Mapping Model.","authors":"Alexandra Metsini, Linda Ryen, Scott Montgomery, Anu Molarius, Åke Svensson, Laura Kobyletzki","doi":"10.2340/actadv.v106.adv-2025-0277","DOIUrl":"10.2340/actadv.v106.adv-2025-0277","url":null,"abstract":"Atopic dermatitis (AD) is associated with impaired health-related quality of life (HRQoL), especially in moderate-to-severe disease. The Dermatology Life Quality Index (DLQI) is the most widely used dermatology-specific measure, whereas the EuroQol Five-Dimension, Five-Level questionnaire (EQ-5D-5L), a generic preference-based instrument, assesses health status across diseases. This study examined the relationship between DLQI and EQ-5D-5L in Swedish adults with ADatopic dermatitis and developed a mapping model to estimate EQ-5D-5L utilities from DLQI scores. In this cross-sectional study, 112 Swedish adults with self-reported physician-diagnosed ADatopic dermatitis, recruited through the Swedish Asthma and Allergy Patient Association, completed both questionnaires. DLQI scores correlated strongly and negatively with EQ-5D-5L index values (r=--0.64, p<0.001). Each 5-point increase in DLQI corresponded on average to a 0.07 decrease in EQ-5D-5L utility. A fractional logit regression model including covariates age, sex, and disease severity, showed good calibration and explained 27 % of the variance in EQ-5D-5L values. These findings demonstrate that DLQI scores meaningfully reflect generic HRQoL among adults with ADatopic dermatitis and can be used to estimate EQ-5D-5L utilities when preference-based data are unavailable. The results enhance understanding of how DLQI relaterelates to overall health status and support the application of DLQI-derived utilities in cost-effectiveness analyses and health technology assessments.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13230340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148147847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell-free DNA Levels in Cellulitis: A Cross-sectional Prospective Study. 蜂窝织炎的游离DNA水平：一项横断面前瞻性研究。

IF 3.7 4区医学

Acta dermato-venereologica Pub Date : 2026-06-02 DOI: 10.2340/actadv.v106.adv-2025-0020

Chaya Bracha Gordon, Ayelet Ollech, Gidon Test, Omer Last, Amos Douvdevani, Amir Horev

{"title":"Cell-free DNA Levels in Cellulitis: A Cross-sectional Prospective Study.","authors":"Chaya Bracha Gordon, Ayelet Ollech, Gidon Test, Omer Last, Amos Douvdevani, Amir Horev","doi":"10.2340/actadv.v106.adv-2025-0020","DOIUrl":"10.2340/actadv.v106.adv-2025-0020","url":null,"abstract":"Cellulitis is a prevalent inflammatory dermatosis caused by bacterial infection that lacks a definitive quantitative biomarker for assessing disease activity and monitoring therapeutic response, leading to diagnostic ambiguity and management challenges. Cell-free DNA (cfDNA), consisting of short nucleic acid fragments released into circulation from necrotic and apoptotic cells, represents a potential objective measure of systemic inflammation. We hypothesized that cfDNA levels would be elevated in patients with cellulitis and correlate with established inflammatory parameters and clinical outcomes. We conducted a cross-sectional prospective study of 36 patients with confirmed cellulitis and 30 healthy controls. Plasma cfDNA levels were quantified at baseline (admission), 72 hours after antibiotic initiation, at discharge, and at 3-week follow-up. We assessed correlations between cfDNA and traditional inflammatory markers, including C-reactive protein (CRP) and white blood cell (WBC) counts, as well as patient-reported pain scores. Patients with cellulitis exhibited significantly elevated plasma cfDNA levels at admission compared with healthy controls. Following antibiotic therapy, cfDNA levels declined rapidly and were positively correlated with reductions in WBCwhite blood cell/neutrophil counts. Higher cfDNA levels were also associated with increased subjective pain scores. These findings suggest that cfDNA may serve as a promising biomarker for the diagnosis of cellulitis and for objectively monitoring treatment efficacy, with potential utility as an objective proxy for pain severity.","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":"106 ","pages":""},"PeriodicalIF":3.7,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148147776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0