Acta Chirurgica Belgica最新文献_第9页

Factors influencing postoperative recurrence of early-stage non-small cell lung cancer. 影响早期非小细胞肺癌术后复发的因素。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-07-05 DOI: 10.1080/00015458.2023.2231210

Tevfik Ilker Akcam, Ahmet Kayahan Tekneci, Tiffany Melissa Ergin, Rza Memmedov, Ayse Gul Ergonul, Ali Ozdil, Kutsal Turhan, Alpaslan Cakan, Ufuk Cagırıcı

{"title":"Factors influencing postoperative recurrence of early-stage non-small cell lung cancer.","authors":"Tevfik Ilker Akcam, Ahmet Kayahan Tekneci, Tiffany Melissa Ergin, Rza Memmedov, Ayse Gul Ergonul, Ali Ozdil, Kutsal Turhan, Alpaslan Cakan, Ufuk Cagırıcı","doi":"10.1080/00015458.2023.2231210","DOIUrl":"10.1080/00015458.2023.2231210","url":null,"abstract":"Purpose: This study aims to explain the factors that may influence recurrence after surgical resection for early non-small cell lung cancer (NSCLC).Methods: A retrospective analysis was made of 302 patients who underwent lung resection for stage I-IIA NSCLC in our clinic between January 2014 and August 2021.Results: The recurrence rate was higher in patients with squamous cell carcinoma (SCC) than in those with adenocarcinoma (AC) (p = 0.004). Disease-free survival (DFS) was shorter in SCC (p = 0.004). According to histopathological subtypes, the presence of lymphovascular invasion (LVI), vascular invasion (VI), visceral pleural invasion (VPI) and tumor spread through air spaces (STAS) caused an increased risk of recurrence ((p = 0.004), (p = 0.001), (p = 0.047), (p = < 0.001)) and shorter DFS ((p = 0.002), (p = < 0.001), (p = 0.038), (p = < 0.001)). LVI and VI was more common in patients with distant recurrence (p = 0.020, p = 0.002), while the STAS was more common with locoregional recurrence (p = 0.003).Conclusion: The presence of LVI, VI, VPI, and STAS are negative risk factors for recurrence and DFS in all patients and in patients with AC. In patients with SCC, the diagnosis of SCC itself and the presence of STAS were risk factors for recurrence and DFS. Moreover, the risk of distant recurrence is higher in the presence of LVI or VI, and the risk of locoregional recurrence in the presence of STAS is higher.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"121-130"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10127412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intrapericardial liver herniation after coronary artery bypass grafting: a case report of minimally invasive repair with 20-year follow-up. 冠状动脉旁路移植术后的心包内肝疝：一例微创修复病例报告及 20 年随访。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-06-06 DOI: 10.1080/00015458.2023.2217565

Matthias Van Aerde, Frederic Lebrun, Georges Decker

{"title":"Intrapericardial liver herniation after coronary artery bypass grafting: a case report of minimally invasive repair with 20-year follow-up.","authors":"Matthias Van Aerde, Frederic Lebrun, Georges Decker","doi":"10.1080/00015458.2023.2217565","DOIUrl":"10.1080/00015458.2023.2217565","url":null,"abstract":"Background: Transdiaphragmatic intrapericardial herniation (DIPH) of intra-abdominal organs is a rare but potentially life-threatening phenomenon often requiring urgent repair. There are currently no guidelines on the preferred repair technique in this situation.Methods: Retrospective case report with long-term follow-up. We describe a case in which the left liver herniated into the pericardium after coronary artery bypass grafting (CABG) using the right gastroepiploic artery (RGEA).Results: Urgent laparoscopic reduction of the liver herniation and repair of the large diaphragmatic defect was performed using an expanded polytetrafluoroethylene (ePTFE) mesh in a 50 year old male patient. Hemodynamic instability normalized after the hernia reduction. The postoperative course was uneventful. CT-scan evaluation after 9 and 20 years of follow-up showed perfect integrity of the mesh.Conclusion: A laparoscopic approach for DIPH is feasible in emergency situations provided sufficient hemodynamic stability of the patient. On-lay ePTFE mesh repair is a valid option for such repairs. We illustrate the long-term durability and safety of ePTFE for DIPH repair in what seems to be by far the longest documented follow-up after laparoscopic ePTFE mesh repair for DIPH.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"153-155"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9581130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcomes of robotic versus laparoscopic ventral mesh rectopexy for rectal prolapse. 机器人与腹腔镜腹侧网片直肠切除术治疗直肠脱垂的效果。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2024-02-05 DOI: 10.1080/00015458.2023.2191073

Ahmed M Chaoui, Ismaël Chaoui, Frederick Olivier, Joachim Geers, Mohamed Abasbassi

{"title":"Outcomes of robotic versus laparoscopic ventral mesh rectopexy for rectal prolapse.","authors":"Ahmed M Chaoui, Ismaël Chaoui, Frederick Olivier, Joachim Geers, Mohamed Abasbassi","doi":"10.1080/00015458.2023.2191073","DOIUrl":"10.1080/00015458.2023.2191073","url":null,"abstract":"Introduction: Minimally invasive ventral mesh rectopexy is considered the standard of care in the surgical management of rectal prolapse syndromes in fit patients. We aimed to investigate the outcomes after robotic ventral mesh rectopexy (RVR) and compare them with our laparoscopic series (LVR). Additionally, we report the learning curve of RVR. As the financial aspect for the use of a robotic platform remains an important obstacle to allow generalized adoption, cost-effectiveness was also evaluated.Patients and methods: A prospectively maintained data set including 149 consecutive patients who underwent a minimally invasive ventral rectopexy between December 2015 and April 2021 was reviewed. The results after a median follow-up of 32 months were analyzed. Additionally, a thorough assessment of the economic aspect was performed.Results: On a total of 149 consecutive patients 72 underwent a LVR and 77 underwent a RVR. Median operative time was comparable for both groups (98 min (RVR) vs. 89 min (LVR); p = 0.16). Learning curve showed that an experienced colorectal surgeon required approximately 22 cases in stabilizing the operative time for RVR. Overall functional results were similar in both groups. There were no conversions or mortality. There was, however, a significant difference (p < 0.01) in hospital stay in favor of the robotic group (1 day vs. 2 days). The overall cost of RVR was higher than LVR.Conclusions: This retrospective study shows that RVR is a safe and feasible alternative for LVR. With specific adjustments in surgical technique and robotic materials, we developed a cost-effective way of performing RVR.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"91-98"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9140891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamics of PTH levels in the development of post-operative hypoparathyroidism. 术后甲状旁腺功能减退症发病过程中PTH水平的动态变化。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-03-28 DOI: 10.1080/00015458.2023.2194598

José Alberto Vilar Tabanera, Joaquín Gómez Ramirez, Philip Brabyn, Alberto G Barranquero, Ana Puerta Vicente, Belén Porrero, Patricia Luengo, José María Fernández Cebrián

{"title":"Dynamics of PTH levels in the development of post-operative hypoparathyroidism.","authors":"José Alberto Vilar Tabanera, Joaquín Gómez Ramirez, Philip Brabyn, Alberto G Barranquero, Ana Puerta Vicente, Belén Porrero, Patricia Luengo, José María Fernández Cebrián","doi":"10.1080/00015458.2023.2194598","DOIUrl":"10.1080/00015458.2023.2194598","url":null,"abstract":"Background: Post-operative hypoparathyroidism is the most frequent complication after total thyroidectomy. The identification of preoperative predictors could be helpful to identify patients at risk. This study aimed to evaluate the potential influence of preoperative PTH levels and their perioperative dynamics as a predictor of transient, protracted, and permanent post-operative hypoparathyroidism.Methods: A prospective, observational study that includes 100 patients who underwent total thyroidectomy between September 2018 and September 2020.Results: Transient hypoparathyroidism was present in 42% (42/100) of patients, 11% (11/100) developed protracted hypoparathyroidism, and 5% (5/100) permanent hypoparathyroidism. Patients who presented protracted hypoparathyroidism had higher preoperative PTH levels. The protracted and permanent hypoparathyroidism rate was higher in groups with greater preoperative PTH [0% group 1 (<40 pg/mL) vs. 5.7% group 2 (40-70 pg/mL) vs. 21.6% group 3 (>70 pg/mL); p = 0.03] and (0 vs. 8.3 vs. 20%; p = 0.442), respectively. The rate of protracted and permanent hypoparathyroidism was higher in patients with PTH at 24 h lower than 6.6 pg/mL and whose percentage of PTH decline was higher than 90%. The rate of transient hypoparathyroidism was higher in patients who showed a PTH decline rate of more than 60%. The percentage of PTH increase one week after surgery in patients with permanent hypoparathyroidism was significantly lower.Conclusion: The prevalence of protracted hypoparathyroidism was higher in groups with higher preoperative PTH levels. PTH levels 24 h after surgery lower than 6.6 pg/mL and a decline of more than 90% predict protracted and permanent hypoparathyroidism. The percentage of PTH increase a week after surgery could predict permanent hypoparathyroidism.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"99-106"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9186451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adenocarcinoma arising from a chronic perianal fistula in a Crohn's disease patient: case report and review of the literature. 克罗恩病患者肛周慢性瘘管引发的腺癌：病例报告和文献综述。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-09-05 DOI: 10.1080/00015458.2023.2205722

Juliette Gosse, Vincenzo Simonelli, Michael Dessily

引用次数: 0

Primary EGIST of the greater omentum - a rare presentation. 原发性大网膜EGIST--一种罕见的表现。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-04-20 DOI: 10.1080/00015458.2023.2201084

Miguel Almeida, Fabiana Sousa, Fernando Resende, Vítor Devesa, António Ferrão, Silvestre Carneiro, Pedro Canão, Elisabete Barbosa, José Barbosa

{"title":"Primary EGIST of the greater omentum - a rare presentation.","authors":"Miguel Almeida, Fabiana Sousa, Fernando Resende, Vítor Devesa, António Ferrão, Silvestre Carneiro, Pedro Canão, Elisabete Barbosa, José Barbosa","doi":"10.1080/00015458.2023.2201084","DOIUrl":"10.1080/00015458.2023.2201084","url":null,"abstract":"Extragastrointestinal stromal tumors (EGISTs) are rare mesenchymal neoplasms, which develop in the retroperitoneum, mesentery, and omentum, lacking continuity to the stomach or intestines. Authors hereby present a female patient with a large heterogeneous abdominal mass as a case of an omental EGIST. A 46-year-old woman was referred to our hospital due to an insidious enlargement and colicky pain in the right iliac fossa. Abdominal palpation revealed a voluminous, freely mobile, and non-pulsatile mesoabdominal bulge expanding to the hypogastrium. On exploratory midline laparotomy, the tumor was densely fused to the greater omentum, not connected to the stomach, without gross involvement of adjacent structures. The large mass was completely excised after adequate mobilization. Immunohistochemical techniques showed strong and diffuse expression of WT1, actin and DOG-1, as well as multifocal c-KIT marking. Mutational study concluded a double mutation of KIT exon 9 and a mutation of PDGFRA exon 18. The patient was submitted to adjuvant treatment with imatinib mesylate 800 mg/day. Despite an extremely diverse presentation, omental EGISTs often remain clinically silent for a long time having enough space to grow before becoming symptomatic. These tumors have a consistent pattern of metastasis that typically spares lymph nodes unlike epithelial gut neoplasms. Surgery remains the preferred treatment for non-metastatic EGISTs of the greater omentum. It is possible that DOG-1 will supplant KIT as the leading marker in the future. The scarcity of knowledge on omental EGISTs implies a close monitoring of these patients to detect local relapse or distant metastasis.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"137-142"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9319772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnets and children: a dangerous combination. 磁铁与儿童：危险的组合

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-06-05 DOI: 10.1080/00015458.2023.2219086

X De Raeymaeker, S Van Cauwenbergh, B Houben, A Karimi, G Sergeant, B Appeltans

{"title":"Magnets and children: a dangerous combination.","authors":"X De Raeymaeker, S Van Cauwenbergh, B Houben, A Karimi, G Sergeant, B Appeltans","doi":"10.1080/00015458.2023.2219086","DOIUrl":"10.1080/00015458.2023.2219086","url":null,"abstract":"Background: Accidental ingestion of foreign bodies is a common problem in children. Fortunately, the gastrointestinal tract is quite resilient to foreign bodies. On the other hand, the ingestion of magnets can result in enormous morbidity. Because of their natural tendency to firmly adhere they can cause intestinal obstruction, pressure necrosis, fistula formation or perforation. With this case report, we aim to raise awareness of the risks that these magnets pose to children.Methods: We describe a case of intestinal perforation caused by the separate ingestion of multiple magnets from a children's toy (buckyballs, Neodymium spheres) by a two-year-old boy. A search in the Pubmed database showed some publications and varied management guidelines.Results: The boy was treated with an exploratory laparoscopy converted to a mini-laparotomy. We removed the four magnets through separate enterotomies. Postoperative recovery was uneventful. The boy was discharged on a postoperative day five and had no complications at three months follow-ups.Conclusion: Accidental ingestion of multiple magnets is rare but can create a life-threatening situation in children. If the magnets are still in the stomach, endoscopic retrieval is needed. If they are beyond the stomach, in asymptomatic cases close clinical and radiographic vigilance is mandatory. When symptomatic we advise urgent removal. If treated on time, the surgical outcome is good and fast recovery is expected.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"156-159"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9945186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Botulinum toxin injection in outpatients for chronic anal fissure. 为门诊慢性肛裂患者注射肉毒杆菌毒素。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-07-14 DOI: 10.1080/00015458.2023.2234179

Şeref Dokcu, Salim İlksen Başçeken

{"title":"Botulinum toxin injection in outpatients for chronic anal fissure.","authors":"Şeref Dokcu, Salim İlksen Başçeken","doi":"10.1080/00015458.2023.2234179","DOIUrl":"10.1080/00015458.2023.2234179","url":null,"abstract":"Objectives: The aim of the study was to evaluate the effect of botulinum toxin (BT) injection on fissure healing in the treatment of chronic anal fissure (CAF) in outpatient conditions without any analgesia and sedation to the internal anal sphincter (IAS). The primary outcome measure was post-procedural pain. The secondary outcome measures were fissure healing and complications.Methods: Prospectively preserved data of 67 patients who received BT injections for CAF were analyzed prospectively. Demographic data, duration of symptomatic improvement, fissure location and number, parity, post-procedural pain, complications, continence status, response to treatment, and duration of follow-up were examined. Participants received bilateral (50 + 50 units) BT injections into the internal anal sphincter (IAS) in an outpatient setting.Results: Symptomatic improvement was observed in 58% of patients within 1 week. The complete response rate to treatment was 82% at a mean follow-up of 6 months. Patients with partial response to treatment (10%) were successfully treated with topical therapy, and patients with persisting fissures (8%) were successfully treated with partial lateral internal sphincterotomy (LIS). 14 patients (21%) reported some degree of transient incontinence at follow-up. Multiparous women experienced more symptoms of Incontinence (p = 0.00). Pre- and post-procedural Vas Score median values were 4. The 7th-week VAS score median value was 3.Conclusion: Dysport injection under sedation-free outpatient conditions is an effective and safe alternative to LIS for the treatment of CAF, with tolerable procedural pain. All patients should be warned of transient incontinence.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"131-136"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9779045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical treatment of constrictive pericarditis at a single center: 10 years of experience. 单一中心的缩窄性心包炎手术治疗：十年经验

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-05-26 DOI: 10.1080/00015458.2023.2216377

Mehmet Ali Yeşiltaş, Ali Aycan Kavala, Saygin Turkyilmaz, Yusuf Kuserli, Gülsüm Türkyilmaz, Hasan Toz, Can Özen

{"title":"Surgical treatment of constrictive pericarditis at a single center: 10 years of experience.","authors":"Mehmet Ali Yeşiltaş, Ali Aycan Kavala, Saygin Turkyilmaz, Yusuf Kuserli, Gülsüm Türkyilmaz, Hasan Toz, Can Özen","doi":"10.1080/00015458.2023.2216377","DOIUrl":"10.1080/00015458.2023.2216377","url":null,"abstract":"Background: Constrictive pericarditis (CP) is a pericardial disease characterized by the pericardium becoming calcified or fibrotic as a result of chronic inflammation, which impairs diastolic filling by compressing the cardiac chambers. Pericardiectomy is a promising surgical option for treating CP. In this study, we reviewed over 10 years of preoperative, perioperative, and short-term postoperative follow-ups of patients who underwent pericardiectomy for constrictive pericarditis at our clinic.Methods: Between January 2012 and May 2022, 44 patients were diagnosed with constrictive pericarditis. Twenty-six patients underwent pericardiectomy for CP. Median sternotomy is the surgical approach of choice because it provides easy access for complete pericardiectomy.Results: The patient median age was 56 (min: 32, max: 71), and 22 out of 26 patients (84.6%) were male. Twenty-one patients (80.8%) complained of dyspnea, which was the most common reason for admission. Twenty-four patients (92.3%) were scheduled for elective surgery. Cardiopulmonary bypass (CPB) was used during the procedure in six patients (23%). The duration of intensive care stay was two days (min: 1, max: 11), and the total hospitalization was six days (min: 4, max: 21). No in-hospital mortality was observed.Conclusion: The median sternotomy approach provides a critical advantage in terms of performing a complete pericardiectomy. Although CP is a chronic condition, early diagnosis and planning of pericardiectomy before irreversible deterioration of cardiac function leads to a notable reduction in mortality and morbidity.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"107-113"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyperfunctioning papillary thyroid carcinoma - a case report and literature review. 功能亢进性甲状腺乳头状癌--病例报告和文献综述。

IF 0.8 4区医学

Acta Chirurgica Belgica Pub Date : 2024-04-01 Epub Date: 2023-05-09 DOI: 10.1080/00015458.2023.2210699

Juliana Pereira-Macedo, Bárbara Freire, Carlos Macedo-Oliveira, João Mendes, Márcia Carvalho, João Rocha-Neves, Sofia Fonseca, Margarida Vinagreiro, Ricardo Lemos, Nair Silva, Francisco Sampaio

{"title":"Hyperfunctioning papillary thyroid carcinoma - a case report and literature review.","authors":"Juliana Pereira-Macedo, Bárbara Freire, Carlos Macedo-Oliveira, João Mendes, Márcia Carvalho, João Rocha-Neves, Sofia Fonseca, Margarida Vinagreiro, Ricardo Lemos, Nair Silva, Francisco Sampaio","doi":"10.1080/00015458.2023.2210699","DOIUrl":"10.1080/00015458.2023.2210699","url":null,"abstract":"Background: Malignant hyperfunctioning thyroid nodules are rare and more likely to occur in follicular cancer types rather than papillary variants. The authors present a case of a papillary thyroid carcinoma associated with a hyperfunctioning nodule.Methods: A single adult patient submitted to total thyroidectomy with the presence of thyroid carcinoma within hyperfunctioning nodules was selected. Additionally, brief literature was conducted.Results: An asymptomatic 58-year-old male was subjected to routine blood analysis and a TSH level of <0.003 mIU/L was found. Ultrasonography revealed a 21 mm solid, hypoechoic, and heterogenous nodule with microcalcifications in the right lobe. A fine needle aspiration guided by ultrasound resulted in a follicular lesion of undetermined significance. A 99mTc thyroid scintigram was followed and identified a right-sided hyperfunctioning nodule. Another cytology was performed and a papillary thyroid carcinoma was derived as a result. The patient underwent a total thyroidectomy. Postoperative histology confirmed the diagnosis and a tumor-free margin with no vascular or capsular invasions.Conclusion: Hyperfunctioning malignant nodules are a rare association, although a careful approach should be led since major clinical implications arise. Selective fine needle aspiration in all suspicious ≥1 cm nodules should be considered.","PeriodicalId":6935,"journal":{"name":"Acta Chirurgica Belgica","volume":" ","pages":"147-152"},"PeriodicalIF":0.8,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9421962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0