中国疾病预防控制中心周报最新文献

{"title":"Reported Cases and Deaths of National Notifiable Infectious Diseases - China, April 2025.","authors":"","doi":"10.46234/ccdcw2025.144","DOIUrl":"https://doi.org/10.46234/ccdcw2025.144","url":null,"abstract":"","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 25","pages":"874-875"},"PeriodicalIF":4.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Identification of <i>Burkholderia gladioli</i> pathovar <i>cocovenenans</i> from Black Fungus and Characteristics of the <i>Bon</i> Gene Cluster - Shanghai Municipality, China, 2023.","authors":"Quan Xiao, Chengbing Dai, Xinyu Hong, Zhixin Fang, Jiawei Zhao, Haijian Zhou, Xin Liu, Libei Xiong, Qingli Dong, Min Chen, Huanyu Wu, Hongzhi Zhang","doi":"10.46234/ccdcw2025.143","DOIUrl":"10.46234/ccdcw2025.143","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong><i>Burkholderia gladioli</i> (<i>B. gladioli</i>) pathovar <i>cocovenenans</i> (<i>BGC</i>), a foodborne pathogen, can cause lethal poisoning. Most cases have been reported in China, primarily originating from fermented cereal products.</p><p><strong>What is added by this report?: </strong>This study investigated the prevalence of <i>BGC</i> contamination in commercially available fungi and analyzed the environmental conditions for bongkrekic acid (BA) production in Shanghai. The overall detection rate of B. gladioli in the 85 samples was 44.7% . The highest detection rate was 94.4%, in dried black fungus, followed by fresh <i>Tremella fuciformis</i> (<i>T. fuciformis</i>) with 16.6%, fresh black fungus with 9.1%, and dried T. fuciformis with 3.8%. BGC was detected only in dried black fungus, with a detection rate of 39% . The results of this study demonstrate that all <i>BGC</i> strains carry the <i>bon</i> gene cluster encoding BA, indicating that <i>bonABCDFGHIJKLM</i> plays an essential role in the biosynthesis of BA.</p><p><strong>What are the implications for public health practice?: </strong>Diagnostic polymerase chain reaction methods could enable rapid identification of BA-producing <i>BGC</i>, providing a potential clinical risk marker. People should avoid eating fungi products soaked 24 hours or more, no matter the temperature.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 25","pages":"869-873"},"PeriodicalIF":4.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Disinfection Efficacy on Bacterial Contamination of Hospital Surfaces - China, 2007-2022.","authors":"Baoying Zhang, Hongyang Duan, Jiaqi Wang, Liubo Zhang, Jin Shen","doi":"10.46234/ccdcw2025.135","DOIUrl":"10.46234/ccdcw2025.135","url":null,"abstract":"<p><strong>Introduction: </strong>The study aims to monitor the dynamics of bacterial contamination on hospital surfaces and assess the effectiveness of disinfection procedures for controlling bacterial contamination in hospitals and protecting patient safety.</p><p><strong>Methods: </strong>This survey was conducted in sentinel hospitals across 31 provincial-level administrative divisions (PLADs) in China from 2007 to 2022. Surface samples were collected from each site before and after disinfection. Bacterial concentrations were measured using the pour plate method, while pathogenic bacteria were isolated and identified using selective media.</p><p><strong>Results: </strong>The overall qualified rate for total plate count was 85.7% (41,474/48,367). Pathogenic bacteria were detected in 577 (5.2%) of the 14,665 samples. Significant differences were observed in the qualified rate of total plate count (<i>χ</i> ²=14.627, <i>P</i><0.05) and the positive rate of pathogenic bacteria (<i>χ</i> ²=266.700, <i>P</i><0.05) among primary, secondary, and tertiary hospitals. Significant differences were also found in the qualified rate of total plate count among four environmental classes (<i>χ</i> ²=775.700, <i>P</i><0.05) and seventeen departments (<i>χ</i> ²=1606.000, <i>P</i><0.05). The qualified rate of total plate count after disinfection (89.5%) was higher than before disinfection (81.8%), while the positive rate of pathogenic bacteria after disinfection (3.8%) was lower than before disinfection (4.3%).</p><p><strong>Conclusions: </strong>Routine disinfection significantly reduces microbial contamination levels on hospital surfaces. Microbiological monitoring of hospital surfaces is a valuable tool for assessing environmental contamination and the effectiveness of disinfection procedures.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 24","pages":"831-837"},"PeriodicalIF":4.3,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Comprehensive Strategy on Mortality in Heterosexually Transmitted HIV-Infected Individuals - Liangshan Prefecture, Sichuan Province, China, 2008-2024.","authors":"Ruiying Liang, Fangfang Chen, Yan Zhao, Ju Wang, Decai Zhao, Jiejun Yu, Houlin Tang, Jian Li, Zhongfu Liu","doi":"10.46234/ccdcw2025.138","DOIUrl":"10.46234/ccdcw2025.138","url":null,"abstract":"<p><p>A comprehensive strategy integrating universal human immunodeficiency virus (HIV) testing, real-time patient tracking, and enhanced antiretroviral therapy (ART) within a poverty-alleviation framework was implemented to curb the HIV epidemic in Liangshan Prefecture. This study aimed to quantify its impact on HIV treatment coverage and mortality among heterosexually transmitted HIV-infected individuals. Data on heterosexually transmitted HIV infections in Liangshan from 2008 to 2024 were extracted from China's HIV/acquired immunodeficiency syndrome (AIDS) Comprehensive Response Information Management System (CRIMS) database. Cox proportional hazards models were used to estimate the effectiveness of the comprehensive strategy on mortality. Interrupted time series analysis examined trends and changes in treatment coverage and mortality before and after implementation. Subgroup analysis investigated outcomes variations across different populations. Among 37,034 eligible HIV-infected individuals, 7,302 deaths occurred. Not receiving ART was the strongest risk factor for mortality [hazard ratio (<i>HR</i>): 17.74]. The comprehensive strategy led to a 21.62% immediate increase and a 1.48% annual increase in treatment coverage, accompanied by a 0.47% decline in mortality per year [95% confidence interval (<i>CI</i>): -0.73, -0.21]. By 2024, the mortality rate was 4.89% lower than the expected level (95% <i>CI</i>: -8.02, -1.75), representing an 81.2% reduction. Reductions were greatest among males, residents of key counties, and patients at the HIV infection stage. The comprehensive strategy in Liangshan significantly improved treatment coverage and reduced mortality among heterosexually infected individuals. Further efforts are needed to promote early diagnosis, rapid ART initiation, and tailored care support for advanced disease. This comprehensive model offers an adaptable template for high-burden, resource-limited settings.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 24","pages":"843-850"},"PeriodicalIF":4.3,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiological and Population Characteristics of Seroprevalence of TTIs Among Voluntary Blood Donors - Guangzhou City, Guangdong Province, China, 2014-2023.","authors":"Feifeng Li, Junmou Xie, Wenbo Gao, Fenfang Liao, Haojian Liang, Rongsong Du, Zhongping Li, Yongmei Nie, Yongshui Fu, Ru Xu, Shijie Li, Hao Wang, Huaqin Liang","doi":"10.46234/ccdcw2025.133","DOIUrl":"10.46234/ccdcw2025.133","url":null,"abstract":"<p><strong>Introduction: </strong>Transfusion-transmitted infections (TTIs) pose significant public health challenges. Screening potential blood donors for hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), and Treponema pallidum (TP), along with ongoing monitoring of epidemiological data on TTIs among donors, is essential to ensure blood safety.</p><p><strong>Methods: </strong>This study conducted a retrospective analysis of the seroprevalence of HBsAg, anti-HCV, anti-HIV, and anti-TP among 3,111,265 blood donation events in Guangzhou from 2014 to 2023, investigating their relationships with demographic characteristics such as gender, age, and donation status.</p><p><strong>Results: </strong>The findings indicated that the overall seroprevalence of TTIs among blood donations was 866.21 per 100,000, demonstrating a declining trend over the ten-year period. Seroprevalence rates of transfusion-transmissible infections also exhibited a downward trend across various demographic groups. Notably, male donors, first-time donors, and older donors demonstrated higher seroprevalence rates for TTIs.</p><p><strong>Conclusions: </strong>While the overall seroprevalence rate of transfusion-transmissible infections among blood donors remains relatively low, significant disparities exist among different demographic groups. It is necessary of sustained TTIs monitoring among blood donors to guide public health interventions and donor screening practices.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 24","pages":"814-820"},"PeriodicalIF":4.3,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of <i>Salmonella enterica</i> Serotype 4,[5],12:i:- from Human Sources: Antimicrobial Resistance, Genotypic Diversity and Emergence of Carbapenem Resistance - China, 2017-2023.","authors":"Huiying Sun, Zhigang Cui, Xiaoli Du, Fenxia Fan, Bowei Sun, Baowei Diao, Haijian Zhou, Biao Kan, Meiying Yan","doi":"10.46234/ccdcw2025.134","DOIUrl":"10.46234/ccdcw2025.134","url":null,"abstract":"<p><strong>Introduction: </strong><i>Salmonella</i> 4,[5],12:i:-, a globally emerging pathogen with multidrug resistance (MDR), is spreading in China. Nationwide data on the antimicrobial resistance (AMR) and genomic characteristics of <i>Salmonella</i> 4,[5],12:i:- from human sources in China are scarce. This study aimed to characterize the prevalence, genetic diversity, and AMR profiles of <i>Salmonella</i> 4,[5],12:i:- in China.</p><p><strong>Methods: </strong>All information, including geographical data, antimicrobial susceptibility test results, and whole-genome sequences, was extracted from the Chinese Pathogen Identification Network database from 2017 to 2023. Antimicrobial resistance phenotypes of 2,736 human-derived isolates were determined, and genomic analysis was applied to assess their genetic heterogeneity. Additionally, resistance genes were detected.</p><p><strong>Results: </strong><i>Salmonella</i> 4,[5],12:i:- strains exhibited varying levels of resistance to the tested antibiotics, with an overall resistance rate of 98.83%, MDR rate of 87.98%, and cefotaxime resistance of 25.91%. An increasing trend was observed for resistance to key antibiotics and AMR determinants from 2020-2023. Whole-genome analysis revealed five clades with high genetic diversity (A-E), with 97.33% belonging to ST34. Clade D carried a significant proportion of ESBL genes. Moreover, we identified 15 meropenem-resistant isolates primarily harboring widely distributed plasmids containing multiple resistance genes, including <i>bla</i> _NDM-5 and <i>bla</i> _OXA-10.</p><p><strong>Conclusion: </strong><i>Salmonella</i> 4,[5],12:i:- is highly sporadic in China but remains phylogenetically linked to the prevalent MDR clone with a distinct resistance profile worldwide. The emergence of elevated resistance to third-generation cephalosporins and sharp rise in carbapenem resistance, coupled with the detection of plasmid-mediated resistance determinants, suggests the evolution of endemic MDR clones circulating within China. These findings emphasize the need for enhanced surveillance, stricter regulations on antibiotic use in agriculture, comprehensive risk factor surveys, and targeted interventions to prevent outbreaks.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 24","pages":"821-830"},"PeriodicalIF":4.3,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends in Life Expectancy of HIV-Infected Patients Receiving Antiretroviral Therapy - China, 2013-2023.","authors":"Lai Wei, Hanlu Jia, Yunxia Geng, Zhihui Dou, Decai Zhao, Xiumin Gan, Yan Zhao","doi":"10.46234/ccdcw2025.136","DOIUrl":"10.46234/ccdcw2025.136","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>With the expanding coverage of antiretroviral therapy (ART), life expectancy among people living with human immunodeficiency virus (HIV) has increased significantly. However, relevant research evidence in China remains very limited.</p><p><strong>What is added by this report?: </strong>From 2013 to 2023, China witnessed a remarkable improvement in life expectancy among HIV-infected patients receiving ART, with the disparity compared to the general population narrowing annually.</p><p><strong>What are the implications for public health practice?: </strong>Our findings recognize the remarkable progress made in ART implementation in China over the past decade, providing timely evidence for improving the health status of HIV population and addressing the emerging challenges of an aging HIV population.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 24","pages":"838-842"},"PeriodicalIF":4.3,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HPV Genotypes and Associated Disease Prevalence in Males with Confirmed HPV Exposure - Shenzhen City, Guangdong Province, China, 2018-2022.","authors":"Heng Li, Nini Li, Feifei Huang, Liping Ding, Xiaoping Hong, Dongzhou Liu","doi":"10.46234/ccdcw2025.131","DOIUrl":"10.46234/ccdcw2025.131","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong>Human papillomavirus (HPV) is a globally prevalent sexually transmitted infection, with multiple genotypes strongly associated with cancers and other diseases. While extensive epidemiological data exist for HPV in females, studies on HPV genotype distribution in males, particularly those with confirmed HPV exposure, remain limited.</p><p><strong>What is added by this report?: </strong>This study provides a comprehensive analysis of HPV genotype distribution and its association with clinical outcomes in males with confirmed HPV exposure. The results demonstrate that low-risk HPV genotypes predominate in this population, with certain diseases showing unique HPV genotype associations. Additionally, older males exhibited a greater tendency toward multiple genotype co-infections.</p><p><strong>What are the implications for public health practice?: </strong>This study underscores the importance of including males in HPV vaccination programs. Expanding vaccination coverage to males, combined with early screening and targeted public health education, can effectively reduce HPV transmission between sexes and decrease the overall burden of HPV-related diseases.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 23","pages":"802-807"},"PeriodicalIF":4.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Foodborne Disease Outbreak Caused by <i>Salmonella</i> - Guiyang City, Guizhou Province, China, September 2024.","authors":"Peipei Zuo, Hua Dai, Qianqian Zhou, Jiajun Jiang, Fei Yuan, Yanxia Zhou, Anzhong Wu, Yiya Liu, Hua Guo","doi":"10.46234/ccdcw2025.098","DOIUrl":"10.46234/ccdcw2025.098","url":null,"abstract":"<p><strong>What is already known about this topic?: </strong><i>Salmonella</i> infection represents a common etiology of foodborne disease outbreaks in educational settings, posing substantial health risks to both students and faculty while simultaneously generating significant public concern. This constitutes a major public health challenge requiring vigilant surveillance and intervention.</p><p><strong>What is added by this report?: </strong>On September 11, 2024, the local center for disease control and prevention received notification from a school physician regarding a clustered foodborne disease outbreak at a middle school. Investigators promptly deployed to assess the situation. Based on comprehensive epidemiological investigations, environmental hygiene assessments, clinical symptomatology, and laboratory analyses, the outbreak was determined to be caused by <i>Salmonella</i> contamination. Specifically, <i>Salmonella</i> Newport was detected in 22 patients, 1 canteen worker, and 3 food samples.</p><p><strong>What are the implications for public health practice?: </strong>We have implemented measures to identify the pathogenic agent, contaminated food vehicles, and associated risk factors, while emphasizing preventive and control recommendations to mitigate similar incidents in the future. The risk of foodborne illness caused by <i>Salmonella</i> Newport contamination warrants serious consideration, and public health practitioners must maintain heightened vigilance against this pathogen.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 23","pages":"808-812"},"PeriodicalIF":4.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Increasing Prevalence of Non-GII.4 Genotypes Causing Norovirus Gastroenteritis Outbreaks - Beijing Municipality, China, 2017-2024.","authors":"Hongbo Jing, Yanhui Yang, Mu He, Yanbo Wang, Yu Zhao, Zhan Li, He Zhang, Nan Jia, Yanmeng Gao, Shengtian Liu, Tao Peng, Miao Jin","doi":"10.46234/ccdcw2025.129","DOIUrl":"10.46234/ccdcw2025.129","url":null,"abstract":"<p><strong>Objectives: </strong>Since 2014, non-GII.4 norovirus genotypes have increasingly challenged the predominance of GII.4, particularly in Asia. This study analyzed the epidemiological and genetic characteristics of norovirus outbreaks from January 2017 to June 2024 in a district of Beijing, China.</p><p><strong>Methods: </strong>We tested 2,016 stool samples collected from 309 acute gastroenteritis outbreaks for norovirus using real-time RT-PCR. Partial polymerase and capsid sequences of norovirus-positive samples were amplified and sequenced for phylogenetic analysis. Additionally, we performed genome amplification and sequence analysis on seven GII.7[P7] strains.</p><p><strong>Results: </strong>Between January 2017 and June 2024, 150 norovirus outbreaks were reported, with GII norovirus causing 83.3% of these outbreaks. We identified 16 distinct genotypes. Among the 102 GII genotype outbreaks, non-GII.4 norovirus outbreaks (81.4%) significantly outnumbered GII.4 norovirus outbreaks (18.6%). The three most prevalent genotypes during the study period were GII.2[P16] (46.1%, 47/102), GII.3[P12] (14.7%, 15/102), and GII.4 Sydney[P16] (12.7%, 13/102). GII.2[P16] predominated in 2017, 2018, and 2020, while GII.3[P12] was the dominant genotype in 2022. Multiple genotypes emerged in 2023. In the first half of 2024, GII.4 Sydney[P16] became predominant (36.9%), while a novel GII.7[P7] variant emerged, accounting for 26.3% of outbreaks. All seven GII.7[P7] genome sequences formed an independent branch in both VP1 and polymerase regions.</p><p><strong>Conclusions: </strong>Our findings demonstrate that non-GII.4 noroviruses play an increasingly important role in outbreaks in Beijing. Continuous surveillance is needed to better understand and control norovirus outbreaks in future epidemic seasons.</p>","PeriodicalId":69039,"journal":{"name":"中国疾病预防控制中心周报","volume":"7 23","pages":"790-795"},"PeriodicalIF":4.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144577027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}