2019 IEEE International Ultrasonics Symposium (IUS)最新文献_第6页

Wave Propagation in the Multilayered Low-pressure Near-space Atmosphere 多层低气压近空间大气中的波传播

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925658

Chao Li, Q. Guo, Hanyin Cui, Rushan Shen, Xiaodong Peng, Xuchen Shen, Yaqin Hou, Qinghua Gao, Jing Wang, Chongxing Liu

引用次数: 0

A General Framework for Channel Domain SVD Clutter Filtering 信道域SVD杂波滤波的通用框架

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925935

Kathryn A. Ozgun, B. Byram

引用次数: 1

CMUT with mechanically coupled plate actuators -Linearized electrostatic modeling 带有机械耦合板致动器的CMUT。线性化静电建模

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925938

Marcel Krenkel, S. Koch, M. Kupnik

引用次数: 1

Acoustic Cluster Therapy displays theranostic capability in enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice 声学簇疗法在增强阿霉素脂质体治疗小鼠人类三阴性乳腺癌的有效性方面显示出治疗能力

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925626

N. Bush, P. Sontum, J. Bamber, A. Healey, Anant Shah, G. Box, V. Kirkin, S. Kotopoulis, S. Kvåle, A. van Wamel, C. de Lange Davies

{"title":"Acoustic Cluster Therapy displays theranostic capability in enhancing the effectiveness of liposomal doxorubicin treatment of human triple negative breast cancer in mice","authors":"N. Bush, P. Sontum, J. Bamber, A. Healey, Anant Shah, G. Box, V. Kirkin, S. Kotopoulis, S. Kvåle, A. van Wamel, C. de Lange Davies","doi":"10.1109/ULTSYM.2019.8925626","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925626","url":null,"abstract":"Acoustic Cluster Therapy (ACT) employs an intravenously-injected dispersion of clusters of microbubbles and oil microdroplets, in combination with ultrasound directed at the tumor, to enhance the delivery of a co-administered drug. Diagnostic ultrasound activates the clusters, causing the droplets to change phase and become large (> 20 m) bubbles which lodge in the tumor capillaries. Delivery-enhancement is then achieved using a low-frequency (e.g. 300 kHz) ultrasound field also directed at the tumor, which causes the stationary bubbles to pulsate whilst in direct contact with the vascular endothelium. ACT has been shown to significantly increase the efficacy of various chemotherapeutics in a variety of tumor models in mice. Here we demonstrate through preclinical in-vivo experiments that the efficacy of treating human triple negative breast cancer in mice with liposomal doxorubicin (Doxil®) is significantly enhanced by ACT; for example, 63 % of animals achieved complete, stable remission, in the group treated with the drug and ACT versus only 10 % for Doxil® alone (p < 0.02). We also show in the same experiments that the ACT contrast enhancement obtained under ultrasound activation of the ACT clusters, either before or during treatment, holds promise as an imaging biomarker for predicting response.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"18 1","pages":"224-226"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83685336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Fully Convolutional Neural Network for Rapid Displacement Estimation in ARFI Imaging 基于全卷积神经网络的ARFI成像快速位移估计

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925911

Derek Y. Chan, D. Morris, M. Palmeri, K. Nightingale

引用次数: 1

Polarization conversion of surface acoustic waves for enhanced microscale actuation applications 用于增强微尺度驱动应用的表面声波偏振转换

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8926272

R. Weser, A. Darinskii, H. Schmidt

引用次数: 0

Investigation of Optical Ultrasound Emission Mechanism Based on CNTs-PDMS Composite CNTs-PDMS复合材料光超声发射机理研究

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925668

Soo Won Kwon, Won Young Choi, K. Park

引用次数: 0

Characterization of High Intensity Ultrasound Exposures by Quantitative Ultrasound 高强度超声暴露的定量超声表征

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925754

V. Barrère, E. Franceschini, D. Melodelima

{"title":"Characterization of High Intensity Ultrasound Exposures by Quantitative Ultrasound","authors":"V. Barrère, E. Franceschini, D. Melodelima","doi":"10.1109/ULTSYM.2019.8925754","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925754","url":null,"abstract":"High Intensity Ultrasound (HIU) is of proven value in the treatment of many medical disorders by using US energy without incisions or radiation. The development of an effective method for guiding HIU therapies remains necessary. Changes in spectral-based Quantitative UltraSound (QUS) parameters have been correlated with the temperature changes during HIU exposure (Ghoshal et al. IEEE UFFC 2016). The aim of this study is to quantify the changes in QUS parameters due to temperature elevation after HIU exposure of ex vivo bovine livers. The QUS experiments are conducted in high frequencies (12-38 MHz) to provide insight into the specific changes in liver tissues that cause the changes of backscatter properties for fixed temperature ranging from 37°C up to 80°C after HIU exposure.Samples of porcine livers are exposed to HIU using a plane 3 MHz transducer with aperture diameter of 4 cm. Samples were heated up to 37, 50, 60, 65, 70, 75, 80°C. After reaching the desired temperature, the sample is cut in half at the center of the lesion. US backscatter signals were recorded from the cut samples by using the Visualsonics Vevo 770 imaging system with the RMV710 probe of center frequency 25 MHz. The backscatter coefficients (BSCs) were estimated using the reference phantom technique and the attenuation coefficients were determined using a standard substitution method.Structural scatterer properties were estimated by fitting the measured BSCs with the spherical Gaussian model (SGM) or with the Structure Factor Model (SFM) to estimate the effective scatterer diameter (ESD) and acoustic concentration (EAC). The QUS parameters estimated by the sparse SGM and the concentrated SFM differ strongly from each other for HIU treated samples and suggests that the treated livers can be considered as concentrated media. Results showed that both integrated BSC and ESD estimated by the SFM increased as a function of temperature.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"67 1","pages":"544-547"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83460230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A High Power Circuit Model of an FBAR Resonator for Use in Filter Design 用于滤波器设计的FBAR谐振器大功率电路模型

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925762

S. Setoodeh, U. Kemiktarak, F. Bayatpur, S. Fouladi, D. Feld

引用次数: 2

Tiled Large Element 1.75D Aperture with Dual Array Modules by Adjacent Integration of PIN-PMN-PT Transducers and Custom High Voltage Switching ASICs 通过相邻集成PIN-PMN-PT换能器和定制高压开关asic，平铺大元件1.75D孔径双阵列模块

2019 IEEE International Ultrasonics Symposium (IUS) Pub Date : 2019-10-01 DOI: 10.1109/ULTSYM.2019.8925552

R. Wodnicki, Yu Liu, Victoria Chiu, D. Stephens, Qifa Zhou, K. Ferrara, Haochen Kang, Di Li, Yizhe Sun, Laiming Jiang, Ruimin Chen, Zeyu Chen, Hayong Jong, J. Foiret

{"title":"Tiled Large Element 1.75D Aperture with Dual Array Modules by Adjacent Integration of PIN-PMN-PT Transducers and Custom High Voltage Switching ASICs","authors":"R. Wodnicki, Yu Liu, Victoria Chiu, D. Stephens, Qifa Zhou, K. Ferrara, Haochen Kang, Di Li, Yizhe Sun, Laiming Jiang, Ruimin Chen, Zeyu Chen, Hayong Jong, J. Foiret","doi":"10.1109/ULTSYM.2019.8925552","DOIUrl":"https://doi.org/10.1109/ULTSYM.2019.8925552","url":null,"abstract":"Tiled large aperture 1.75D/2D transducer arrays with closely integrated ASIC electronics have the potential for implementing high channel count ultrasound probes for novel applications, however they must have high yield for a large number of elements to maintain good image quality. This constraint can be addressed by tiling together a number of smaller array modules to build up the larger aperture. In this work we present recent imaging results for large apertures with multiple tiled array modules integrating 2D arrays of wide bandwidth PIN-PMN-PT 1-3 composite piezo elements with custom-designed ASICs for buffering and multiplexing functions. The ASICs are optimized to obtain increased sensitivity of the high impedance 2D elements using buffering. We have also been developing novel second-generation ASICs to mitigate the effects of switching transients observed while imaging with the first-generation devices.","PeriodicalId":6759,"journal":{"name":"2019 IEEE International Ultrasonics Symposium (IUS)","volume":"27 1","pages":"1955-1958"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83541013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8