Journal of Polymers and the Environment最新文献

{"title":"Toughening Polylactic Acid with Epoxidized Natural Rubber via Altering the Dicumyl Peroxide Mixing Sequence","authors":"Kantima Chaochanchaikul,&nbsp;Poomirat Nawarat,&nbsp;Sirinthorn Thongsang","doi":"10.1007/s10924-024-03429-9","DOIUrl":"10.1007/s10924-024-03429-9","url":null,"abstract":"<div><p>The effect of the sequence to add dicumyl peroxide (DCP) to the polylactic acid (PLA) and epoxidized natural rubber (ENR) blending was investigated. According to the tensile and impact resistance tests, premixing DCP with ENR resulted in blends with better mechanical properties where nearly 20 times improvement of impact strength was observed at 30wt% ENR. In addition, the chemical, morphological, and thermal properties of PLA/ENR blends were investigated via Fourier-transform infrared spectroscopy, scanning electron microscopy, and differential scanning calorimetry analysis, respectively. When DCP is premixed with ENR, DCP could act more effectively as a vulcanizing agent than a compatibilizer, whereas the DCP mixing with PLA/ENR blending of PLA/ENR might lead to more PLA chain scission than DCP premixing with ENR. This study indicated that the toughening of PLA/ENR blends can be significantly enhanced when high ENR vulcanization together with the formation of small PLA phases.</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"230 - 242"},"PeriodicalIF":4.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and Characterization of Papain Loaded Phosphatidyl Choline-PLGA Hybrid Nanoparticles as Novel Drug Delivery Systems","authors":"Aarzoo Sinha,&nbsp;S. Rupachandra","doi":"10.1007/s10924-024-03374-7","DOIUrl":"10.1007/s10924-024-03374-7","url":null,"abstract":"<div><p>Polymeric nanoparticles possess the benefits of biocompatibility and stability, and also enable the controlled release of drugs. The matrix of the nanoparticle highlights the potential for an enhancement in the stability and efficacy of encapsulated therapeutic enzymes. The oral administration of lipid-polymer nanoparticle significantly improves mucus penetration, cellular uptake, and intracellular transport. The objective of this study is to develop a highly effective lipid-polymer nanoparticle system that is capable of absorbing Papain in the intestine. Papain loaded PLGA nanoparticles and Papain loaded PLGA-phosphatidylcholine nanoparticles were identified using FTIR analysis. Drug encapsulation efficiency of Papain loaded PLGA nanoparticles was found to be 49.20% and Papain loaded PLGA-Phosphatidylcholine nanoparticles was 77.5%. The drug loading capacity was found to be 3.75% and 6.84% for the Papain loaded PLGA- nanoparticles and Papain loaded PLGA-Phosphatidylcholine nanoparticles respectively. The antibacterial activity of Papain loaded PLGA-PC nanoparticles was found to be higher as compared to PLGA-PC nanoparticle for <i>Staphylococcus aureus</i> and <i>Escherichia coli</i> respectively. About 98% viability was observed in RAW 264.7 macrophage cells treated with the maximum concentration of 100 µg/ml of Papain-loaded PLGA-PC nanoparticles thereby depicting the biocompatibility property of the nanoparticles.</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"243 - 252"},"PeriodicalIF":4.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cell-Penetrating Peptide Functionalized ZIF-8 (Zn, Fe)/Doxorubicin/Chitosan-Grafted-Polycaprolactone/Curcumin Against A549 Lung Cancer Cells","authors":"Hananeh Kordbacheh,&nbsp;Sahand Eslami,&nbsp;Aryan Rezaee,&nbsp;Parvaneh Ghaderi-shekhi Abadi,&nbsp;Sara Bybordi,&nbsp;Niloufar Ehsanfar,&nbsp;Pouya Goleij,&nbsp;Fariborz SharifianJazi,&nbsp;Mohammad Irani","doi":"10.1007/s10924-024-03382-7","DOIUrl":"10.1007/s10924-024-03382-7","url":null,"abstract":"<div><p>ZIF-8 (Zn, Fe) bimetal–organic framework (BMOF) is used for encapsulation of the doxorubicin (DOX). The BMOF surface is coated by chitosan-grafted- polycaprolactone (Cs-g-PCL) to obtain a pH-sensitive nanocarrier. Curcumin (Cur) was loaded into the Cs-g-PCL, and the surface of nanoparticles coated by transactivating transcriptional factor (TAT) peptide. The capability of TAT peptide-coated Cs-g-PCL/Cur/BMOF/DOX was investigated for lung cancer treatment. More than 95% DOX release from Cs-g-PCL/Cur/BMOF/DOX and TAT peptide-coated Cs-g-PCL/Cur/BMOF/DOX under pH values of 5.5 &amp; 6.8 &amp; 7.4 occurred within 72 ± 0.25 &amp; 120 ± 0.3 &amp; 144 ± 0.3 h and 96 ± 0.2 &amp; 144 ± 0.3 &amp; 168 ± 0.5 h, respectively. MTT assay results indicated that the co-delivery of DOX and Cur resulted in decreasing the cell viability of A549 lung cancer cell up to 22.7 ± 0.2%, and the maximum A549 cancer cells death percentage was 93.5 ± 0.1% using TAT peptide-coated Cs-g-PCL/Cur/BMOF/DOX BMOFs. The flowcytometry and confocal images results demonstrated the synergistic effect of TAT peptide and DOX-Cur anticancer drugs on the apoptosis of A549 cancer cells. The in vivo results indicated the maximum tumor inhibition (relative tumor volume: 0.25 after 20 days) for the tumor-bearing mice treated with TAT peptide-coated Cs-g-PCL/Cur/ZIF-8 (Zn, Fe) /DOX BMOF. Overall, results revealed that the co-delivery of anticancer agents and peptides increase the therapeutic efficacy.</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"581 - 598"},"PeriodicalIF":4.7,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fungicide Film Coating—A New Approach to Potato Tubers Health","authors":"Evgeniy G. Kiselev,&nbsp;Svetlana V. Prudnikova,&nbsp;Tatiana G. Volova","doi":"10.1007/s10924-024-03417-z","DOIUrl":"10.1007/s10924-024-03417-z","url":null,"abstract":"<div><p>Pioneering results of seed-potato health improvement and the suppression of soil-borne infection during the potato production by the preplant coating of tubers with an azoxystrobin-loaded degradable polymer film coating are presented. The film coating was applied to the surface of potato tubers by spraying with a 1% solution of the degradable polymer poly(3-hydroxybutyrate) in dichloromethane mixed with azoxystrobin. The film coating did not damage the tubers or reduce germination. The half-life of the polymer coating in field soil was 25 days. The film degraded gradually from potato planting to the beginning of flowering, ensuring long-term delivery of the fungicide to the plants. In the experimental group, a more effective reduction in the total number of rhizospheric soil fungi, including plant pathogens <i>Alternaria alternata</i> and <i>Fusarium oxysporum</i>, was revealed, compared with the preplant treatment of tubers with the commercial fungicide azoxystrobin (comparison group). The healing effect of the fungicide-loaded coating led to an improvement in the quality of the potato crop. In the experimental group, the total yield and the share of marketable tubers exceeded those of the comparison group by 5.6 t/ha and 8%, respectively. The proportion of Fusarium infected tubers was 8.5% in the experimental group versus 12.1% in the comparison group. The fungicidal effect of a long-term degradable polymer film coating with azoxystrobin was more successful than traditional treatment of tubers with a solution of this fungicide. Thus, the proposed approach is promising for the protection of seed potatoes.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><img></picture></div></div></figure></div></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"177 - 196"},"PeriodicalIF":4.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ZnO nanoparticle-embedded Gellan Gum Based Sponge for Accelerated Wound Healing: An in vitro Study on Physicochemical, Antibacterial and Hemostatic Properties","authors":"Başak Kurin Atasoyu,&nbsp;Gülşen Bayrak,&nbsp;Selen Öztürk,&nbsp;Aysun Kılıç Süloğlu,&nbsp;Bengi Özkahraman,&nbsp;Işık Perçin","doi":"10.1007/s10924-024-03418-y","DOIUrl":"10.1007/s10924-024-03418-y","url":null,"abstract":"<div><p>In the current study, a biocompatible zinc oxide (ZnO) nanoparticle embedded gellan gum (GG) (GG-ZnNP) sponge with excellent antibacterial activity, enhanced wound healing and hemostatic properties was presented. Firstly, ZnO nanoparticles were synthesized by co-precipitation methods and characterized through Fourier transform infrared (FTIR) spectroscopy and X-ray diffraction (XRD) analysis. The size distribution and morphology of the ZnO nanoparticles were investigated by applying dynamic light scattering (DLS) and transmission electron microscopy (TEM). Presence and distribution of the ZnO nanoparticles in GG sponges were examined with Energy-dispersive x-ray spectroscopy (EDX) Thermogravitational Analysis (TGA) conducted to evaluate the thermal stability of GG-ZnO sponges. Following that, ZnO nanoparticles were embedded into GG sponges to enhance their antimicrobial properties. The physicochemical properties of GG-ZnNP sponges were characterized by FTIR, Scanning Electron Microscopy (SEM), swelling and degradation tests. The agar disk diffusion test and colony-forming unit assay findings showed that all GG-ZnNP sponges had a strong antibacterial activity against <i>Escherichia coli (E.coli)</i> and <i>Staphylococcus aureus (S. aureus)</i> bacteria. Furthermore, in vitro blood absorption tests indicated that GG-ZnNP sponges could effectively shorten bleeding time and increase blood absorption capacity. Cell viability studies conducted by MTT and scratch assay with L929 fibroblast cells. MTT assay were performed to found applicable ZnO dose of the sponges to be use as a wound dressings. In vitro scratch assays showed that GG-ZnNP sponges promoted wound closure and re-epithelialization in L929 fibroblast cells at increasing incubation time. GG-ZnNP sponges have a significant and improvable potential for wound dressing applications with their antibacterial and superior hemostatic properties.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><img></picture></div></div></figure></div></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"210 - 229"},"PeriodicalIF":4.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Yarn Production from the Offshore Industry Mooring rope Waste: A Circular Textile Economy Opportunity","authors":"Thaiane Nolasco da Silva,&nbsp;Ana Maria Furtado de Sousa,&nbsp;Ana Lucia Nazareth da Silva,&nbsp;Adriano Alves Passos,&nbsp;Elen Beatriz Acordi Vasques Pacheco","doi":"10.1007/s10924-024-03414-2","DOIUrl":"10.1007/s10924-024-03414-2","url":null,"abstract":"<div><p>Offshore platform decommissioning is a complex process that can cause marine damage. The circular economy can be used to implement sustainable initiatives in the decommissioning process. Mooring ropes, which commonly consist of poly(ethylene terephthalate) (PET) fiber, are one type of waste generated during offshore platform decommissioning. This study aims to demonstrate that the ring spinning process is a sustainable solution to recycling PET fibers from post-industrial mooring ropes (PMR-PET) by producing yarns containing 70–60% PMR-PET. One-way ANOVA and the Cochran test demonstrated that the yarns made with PMR-PET exhibit better tensile properties than those made with 100% commercial PET. Addition of PMR-PET produces a yarn with a higher crystallinity. The lower degradation temperatures of PMR-PET yarns are not enough to limit their use in textile products. This study demonstrates that recycling PMR-PET provides an opportunity to promote the circular economy and develop new yarns in the textile industry.</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"197 - 209"},"PeriodicalIF":4.7,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Effects of Polyethylene Glycol and Cellulose Nanofibers on the Isothermal and Non-isothermal Crystallization Behaviors of Polylactide","authors":"Feng-jiao Li,&nbsp;Xi-tong Yu,&nbsp;Man-feng Gong,&nbsp;Xing-zao Ma,&nbsp;Xiao-jun Chen,&nbsp;Jun Xu,&nbsp;Bao-hua Guo","doi":"10.1007/s10924-024-03412-4","DOIUrl":"10.1007/s10924-024-03412-4","url":null,"abstract":"<div><p>To significantly improve the crystallinity and crystallization rate of polylactide (PLA), plasticizer (polyethylene glycol, PEG) and nucleating agent (cellulose nanofibers, CNFs) were melt-blended with PLA to prepare PLA/PEG/CNF nanocomposites. The effects of PEG and/or CNFs and cooling rate on the crystallization kinetics of PLA were investigated by HS-POM, DSC, and WAXD. The non-isothermal crystallization kinetics of modified PLA samples were evaluated by the Jeziorny’s, Ozawa’s, and Mo’s models, while their non-isothermal crystallization activation energies were determined by Friedman’s method. The polarized optical micrographs showed that CNFs served as effective nucleating agents, increasing the nucleation density of PLA spherulites, but reducing their spherulite sizes; PEG improved the mobility of PLA chains and accelerated the growth rate of PLA spherulites, thus leading to larger spherulite sizes. The non-isothermal crystallization kinetics revealed that the crystallization temperature (<i>T</i>_c), crystallinity (<i>X</i>_C), and crystallization half-time (<i>t</i>_1/2) of all PLA-based samples decreased with increasing cooling rate. At the same cooling rate, the incorporation of 15 wt% PEG or 3 wt% CNFs increased <i>T</i>_c and <i>X</i>_C but decreased <i>t</i>_1/2 of PLA by enhancing spherulite growth rate and providing more crystal nuclei, respectively. Moreover, SEM micrographs showed that the addition of PEG improved the dispersion of CNFs within the PLA matrix, and the synergistic effect of PEG and CNFs more significantly increased <i>T</i>_c and <i>X</i>_C, but reduced <i>t</i>_1/2. The above results demonstrated that the combination of PEG and CNFs significantly enhanced the crystallization performance of PLA, providing insights for the design of high-performance PLA-based materials.</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"78 - 95"},"PeriodicalIF":4.7,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Flame-retardant Performance of Undervalued Polyethylene Terephthalate Waste as a Potential use in Foamed Materials","authors":"Mercedes Santiago-Calvo,&nbsp;Andreas Himmelsbach,&nbsp;Carlos Alonso,&nbsp;Maria-Teresa Fernández,&nbsp;Esteban Cañibano,&nbsp;Christian Brütting,&nbsp;Tobias Standau,&nbsp;Holger Ruckdäschel","doi":"10.1007/s10924-024-03424-0","DOIUrl":"10.1007/s10924-024-03424-0","url":null,"abstract":"<div><p>Nowadays, the post-consumer polyethylene terephthalate (PET) waste from the packaging industry is one of the largest plastic waste streams worldwide. While clear PET waste is commonly recycled and is reused for textile and packaging applications (even with food contact), coloured PET waste`s degraded state limits its reusing potential. This highlights the urgent need to upgrade low-value PET waste. This study focuses on enhancing coloured recycled PET (rPET) quality by introducing an epoxide chain extender (CE) from 0 to 1 wt%, to improve rheological behaviour. Simultaneously, upcycling opportunities are explored by incorporating an eco-friendly phosphorous-based flame retardant (FR) from 0 to 10 wt%, to reduce flammability and thus enabling electrical and electronic applications, among others. The impact of each additive, as well as their combination, is evaluated on the chemical structure, thermal, rheological and burning behaviour of undervalued rPET. The optimal CE content is determined at 0.8 wt%, promoting branched and higher molecular weight polymer chains. Regarding FR, 6, 8 and 10 wt% highly enhance the fire resistance. Furthermore, the combination CE/FR enables a synergistic effect, notably improving burning behaviour. Additionally, the foaming potential of the resulting high-value rPET is assessed for the first time through one-step batch foaming using supercritical CO₂ as foaming agent, aiming to develop lightweight materials endowed with superior burning behaviour. The material containing 0.8 wt% CE reaches the lowest density (200 kg/m³) and a closed cellular structure with smaller cell diameters (8 ± 3 μm). Meanwhile, the combination of 0.8 wt% CE and 6 wt% FR gives rise to a foamed material with density of 659 kg/m³ and cell diameter of 7 μm. Thus, this batch procedure in one-step enables the formation of microcellular foams based on coloured rPET (cell size below 10 μm).</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"161 - 176"},"PeriodicalIF":4.7,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Highly Sensitive Test System for Measuring the Phenolic Index of Wastewater Based on a Biocompatible Composite Material with Carbon Nanotubes","authors":"Tatyana Lavrova,&nbsp;Anna Kharkova,&nbsp;Roman Perchikov,&nbsp;Maria Gertsen,&nbsp;Andrey Shadrin,&nbsp;Vyacheslav Arlyapov","doi":"10.1007/s10924-024-03421-3","DOIUrl":"10.1007/s10924-024-03421-3","url":null,"abstract":"<div><p>A biosensor for the determination of the phenol index in water bodies has been developed using enzymes immobilized on the redox-active polymer surface of a graphite paste electrode. Tyrosinase, laccase, and bacterial cell membrane fractions were used as biological materials. Redox polymers based on bovine serum albumin (BSA) and various electron transport mediators were synthesized for immobilization. It has been shown that a redox polymer based on ferrocene (FC) combined with single-walled carbon nanotubes (SWCNTs) is more promising for use in biosensors than a polymer based on safranin (SAF) based on electrochemical and analytical parameters. The best results were obtained with the “BSA-FC-SWCNT-tyrosinase” bioanalytical system, which has a lower limit of detectable concentrations of 1 × 10⁻³ mg/L, indicating the possibility of monitoring water environments with a phenol concentration corresponding to the maximum permissible concentration (MPC). The maximum analytical signal was generated at a temperature of 30 °С and a pH of 6.8. The biosensor was stable at concentrations of heavy metal ions up to 100 times the MPC, as well as at NaCl concentrations up to 5%. The system was tested on river water samples containing phenol. A statistical analysis of the results showed no significant difference between the biosensor results and those of standard analytical methods. The proposed approach will significantly reduce the analysis time, its labor intensity and cost.</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"63 - 77"},"PeriodicalIF":4.7,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biogenic Synthesis of Ag NPs Adorned Gellan Gum Modified Fe3O4 NPs Towards the Catalytic Reduction of Nitroarenes and the Investigation of Anti-breast Cancer Potential","authors":"Shi Qiu,&nbsp;Xiaofang Hu,&nbsp;Yun Zhao,&nbsp;Attalla F. El-kott,&nbsp;Sally Negm,&nbsp;Ali G. Alkhathami","doi":"10.1007/s10924-024-03380-9","DOIUrl":"10.1007/s10924-024-03380-9","url":null,"abstract":"<div><p>In the realm of nanobiotechnology the bio-inspired and bioengineered nanoparticles have immense impetus in view of their unique and diverse implications. This research describes an eco-friendly method for the in situ synthesis of an Ag NP fabricated over gellan gum functionalized Fe₃O₄ NPs (Fe₃O₄@gellan gum-Ag) and its subsequent catalytic and biological uses. The morphological and physicochemical properties of this material were evaluated applying a variety of instrumental methods, including FT-IR, FE-SEM, TEM, EDS, elemental mapping, XRD, and ICP. The as synthesized Fe₃O₄@gellan gum-Ag NPs was used as a nanocatalyst in the catalytic application to reduce nitrobenzene derivatives. A UV–Vis spectrophotometer was used to track the reduction process. Through eight additional cycles, we assessed the sustainability of this catalyst based on its recyclable qualities. Furthermore, the nanocomposite’s bioapplication for in vitro anticancer research against the breast cell lines MCF-7 and SKBR3 was expanded through the use of the MTT assay. The material caused a dose-dependent reduction in the malignant breast cell line’s cell survival. Regarding the MCF-7 (Michigan Cancer Foundation-7) and SKBR3 (Sloan–Kettering breast cancer) cell lines, the nanocomposite was found to have IC50 values of 41.2 and 39 µg/mL. In the near future, cancer management may appear extremely promising, considering the amazing results the developed nanocomposite demonstrated.</p></div>","PeriodicalId":659,"journal":{"name":"Journal of Polymers and the Environment","volume":"33 1","pages":"570 - 580"},"PeriodicalIF":4.7,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142941115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}