Journal of Leather Science and Engineering最新文献

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Methods for determining the molecular composition of knee joint structures in osteoarthritis: collagen, proteoglycans and water content: a systematic review 确定骨关节炎膝关节结构分子组成的方法:胶原蛋白、蛋白多糖和含水量:系统综述
Journal of Leather Science and Engineering Pub Date : 2024-09-20 DOI: 10.1186/s42825-024-00173-7
Bogdan Raikov, Marina Lipina, Kirill Azarkin, Yuliya Goncharuk, Ivan Vyazankin, Eugene Kalinsky, Tagir Kudrachev, Emirkhan Murdalov, Eugene Nagornov, Gleb Budylin, Evgeny Shirshin, Nataliya Rovnyagina, Vadim Cherepanov, Anton Kurpyakov, Vladimir Telpukhov, Nikita Belov, David Pogosyan, Gennadiy Kavalerskiy, Andrey Gritsyuk, Andrey Garkavi, Alexey Lychagin
{"title":"Methods for determining the molecular composition of knee joint structures in osteoarthritis: collagen, proteoglycans and water content: a systematic review","authors":"Bogdan Raikov,&nbsp;Marina Lipina,&nbsp;Kirill Azarkin,&nbsp;Yuliya Goncharuk,&nbsp;Ivan Vyazankin,&nbsp;Eugene Kalinsky,&nbsp;Tagir Kudrachev,&nbsp;Emirkhan Murdalov,&nbsp;Eugene Nagornov,&nbsp;Gleb Budylin,&nbsp;Evgeny Shirshin,&nbsp;Nataliya Rovnyagina,&nbsp;Vadim Cherepanov,&nbsp;Anton Kurpyakov,&nbsp;Vladimir Telpukhov,&nbsp;Nikita Belov,&nbsp;David Pogosyan,&nbsp;Gennadiy Kavalerskiy,&nbsp;Andrey Gritsyuk,&nbsp;Andrey Garkavi,&nbsp;Alexey Lychagin","doi":"10.1186/s42825-024-00173-7","DOIUrl":"10.1186/s42825-024-00173-7","url":null,"abstract":"<div><p>Osteoarthritis is a degenerative disease that affects articular cartilage, leading to changes on the macro and micro levels of this multi-component tissue. Understanding the processes underlying this pathology plays an important role in planning the following management tactics. Timely detection of the knee joint degradation at the level of tissue changes can prevent its progressive damage due to the early beginning of appropriate treatment. This study aimed to provide an overview of the current level of knowledge about the composition of cartilage and menisci using a wide range of different diagnostic methods. A systematic review of the literature published from 1978 to 2023 was conducted. Original studies of the knee joint cartilage (articular and meniscus) research, reporting content composition and mechanical properties, were included. Studies of the non-knee joint cartilage, tissue research other than cartilage and meniscus, or reporting treatment outcomes were excluded (n = 111). Thirty-one papers were included in this review, which reported on the composition of animal and human cartilage (articular and meniscus). The most frequently investigated parameters were quantitative proteoglycan determination and hydration level of the cartilage. Cartilage and meniscus degeneration, i.e., reduced collagen and proteoglycan content, reduced mechanical properties, and increased hydration level, was shown in every article about osteoarthritis. Among all diagnostic methods, laboratory methods (biochemical and histological analysis) are the most frequently used, compared to the instrumental ones (spectroscopy, MRI, and CT). At the same time, spectroscopy takes the lead and becomes the most common approach for determining cartilage composition (collagen and proteoglycans content).</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00173-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142272987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterisation and tanning effects of purified chestnut and sulfited quebracho extracts 纯化栗木和亚硫酸化坚木提取物的特性和鞣制效果
Journal of Leather Science and Engineering Pub Date : 2024-09-02 DOI: 10.1186/s42825-024-00171-9
Silvia Conca, Vanessa Gatto, Riccardo Samiolo, Samuele Giovando, Andrea Cassani, Elisa Tarabra, Valentina Beghetto
{"title":"Characterisation and tanning effects of purified chestnut and sulfited quebracho extracts","authors":"Silvia Conca,&nbsp;Vanessa Gatto,&nbsp;Riccardo Samiolo,&nbsp;Samuele Giovando,&nbsp;Andrea Cassani,&nbsp;Elisa Tarabra,&nbsp;Valentina Beghetto","doi":"10.1186/s42825-024-00171-9","DOIUrl":"10.1186/s42825-024-00171-9","url":null,"abstract":"<div><p>Vegetable tannins are environmentally friendly tanning agents. However, they generally impart a dark colour to the tanned leather and highly contribute to the organic load in wastewaters. In this study, we employed a purification protocol separately on chestnut tannin (CT) and sulfited quebracho tannin (QT) to obtain the purified fractions (PCT and PQT). These samples were characterised by GPC, <sup>1</sup>H NMR, <sup>13</sup>C NMR, FT-IR, and HPLC–DAD techniques and applied for tanning tests. Through the purification process, non-tannin components and smaller molecules such as gallic acid, glucopyranose, and catechin were effectively removed from CT and QT, which consequently led to the reduced moisture content, pH value, and lighter colour of purified fractions. The crust leathers processed with PCT and PQT showed desirable light shades. Moreover, the organic loads in PCT and PQT tanning wastewater were reduced by 13.5% and 19.1%, respectively, when compared to those in traditional CT and QT tanning wastewater. Additionally, the physical and mechanical characteristics of crust leathers processed with PCT and PQT were comparable to those processed with CT and QT. Thus, purification of vegetable tannins may serve as a feasible strategy for producing light-colored vegetable-tanned leather while minimizing organic pollutant discharge during the vegetable tanning process.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00171-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polycaprolactone strengthening gelatin/nano-hydroxyapatite composite biomaterial inks for potential application in extrusion-based 3D printing bone scaffolds 聚己内酯强化明胶/纳米羟基磷灰石复合生物材料墨水在基于挤压的 3D 打印骨支架中的潜在应用
Journal of Leather Science and Engineering Pub Date : 2024-09-01 DOI: 10.1186/s42825-024-00170-w
Chenxin Wang, Mao Yang, Li Chen, Yijing Stehle, Mingyue Lin, Rui Zhang, Huanshuo Zhang, Jiehui Yang, Min Huang, Yubao Li, Qin Zou
{"title":"Polycaprolactone strengthening gelatin/nano-hydroxyapatite composite biomaterial inks for potential application in extrusion-based 3D printing bone scaffolds","authors":"Chenxin Wang,&nbsp;Mao Yang,&nbsp;Li Chen,&nbsp;Yijing Stehle,&nbsp;Mingyue Lin,&nbsp;Rui Zhang,&nbsp;Huanshuo Zhang,&nbsp;Jiehui Yang,&nbsp;Min Huang,&nbsp;Yubao Li,&nbsp;Qin Zou","doi":"10.1186/s42825-024-00170-w","DOIUrl":"10.1186/s42825-024-00170-w","url":null,"abstract":"<div><p>Extrusion-based three-dimensional (3D) printing of gelatin (Gel) is crucial for fabricating bone tissue engineering scaffolds via additive manufacturing. However, the thermal instability of Gel remains a persistent challenge, as it tends to collapse at mild temperatures. Current approaches often involve simply mixing Gel particles with various materials, resulting in biomaterial inks that lack uniformity and have inconsistent degradation characteristics. In this study, acetic acid was used to dissolve Gel and polycaprolactone (PCL) separately, producing homogeneous Gel/PCL dispersions with optimal pre-treatment performance. These dispersions were then combined and hybridized with nano-hydroxyapatite (n-HA) to create a composite printing ink. By evaluating the printability of the ink, the optimal conditions were identified: a n-HA concentration of 50% (w/w), a printing temperature of 10–15 ℃, a printing pressure of 2.5 bar, and a printing speed of 7 mm/s. The resulting biomaterial inks, with a composition of 25% Gel, 25% PCL, and 50% n-HA, demonstrated excellent printability and stability, along with significantly enhanced mechanical properties. As a result, 3D scaffolds with high printability and shape fidelity can be printed at room temperature, followed by deep freezing at -80 ℃ and cross-linking with vanillin. The Gel-based composite scaffolds demonstrated excellent biocompatibility, cell adhesion, cell viability and nano-hydroxyapatite absorption <i>in vitro</i>. Additionally, <i>in vivo</i> experiments revealed that the bioactive scaffold biodegraded during implantation and significantly promoted bone regeneration at the defect site. This provides a promising strategy for treating bone defects in clinical setting. In conclusion, the Gel/PCL/n-HA biomaterial inks presented here offer an innovative solution for extrusion bioprinting in the field of bone tissue engineering.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00170-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142099885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epoxidized fatty acid tri-ester bio-plasticizer with anti-fogging performance comparable to diisodecyl phthalate 环氧化脂肪酸三酯生物增塑剂,防雾性能与邻苯二甲酸二异癸酯相当
Journal of Leather Science and Engineering Pub Date : 2024-08-02 DOI: 10.1186/s42825-024-00169-3
Siyu Pan, Demeng Liu, Xianchong Sun, Delong Hou, Jun Yan, Qi Zeng, Yi Chen
{"title":"Epoxidized fatty acid tri-ester bio-plasticizer with anti-fogging performance comparable to diisodecyl phthalate","authors":"Siyu Pan,&nbsp;Demeng Liu,&nbsp;Xianchong Sun,&nbsp;Delong Hou,&nbsp;Jun Yan,&nbsp;Qi Zeng,&nbsp;Yi Chen","doi":"10.1186/s42825-024-00169-3","DOIUrl":"10.1186/s42825-024-00169-3","url":null,"abstract":"<div><p>The global scenario on PVC plasticizer is experiencing a drastic change from petroleum-based, toxic di-(2-ethylhexyl) phthalate (DEHP) toward renewable, non-toxic bio-alternatives. However, replacing diisodecyl phthalate (DIDP), a DEHP analogue specifically intended for plasticizing PVC automotive upholstery, with bio-alternative remains a challenge as few bio-plasticizer volatilizes from PVC as slowly as DIDP, a crucial aspect compulsorily required by automotive industry. Here, we demonstrate that covalently attaching two short esters at the <i>α</i>-position of all components of a traditional epoxidized fatty acid methyl ester <i>via</i> a two-step, hydrogen-to-ester nucleophilic substitution in a one-pot procedure yields an epoxidized fatty acid tri-ester bio-plasticizer with remarkably suppressed volatilization from PVC, and hence an extremely low fogging value comparable to DIDP. With this strategy in hand, DIDP, long deemed irreplaceable despite its toxicity and non-renewable nature, may ultimately be phased out.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00169-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141886304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Superamphiphilic aerogels with 2D lamellar structure of gelatin-tuned 3D supramolecular network of collagen fibers for high-performance separation of surfactant-stabilized emulsified oily wastewater 具有明胶调谐三维超分子网络的二维层状结构的超亲水气凝胶,用于高性能分离表面活性剂稳定的乳化含油废水
Journal of Leather Science and Engineering Pub Date : 2024-08-01 DOI: 10.1186/s42825-024-00166-6
Honglian Liu, Hanzhong Xiao, Baicun Hao, Wan Zheng, Yujia Wang, Xin Huang, Bi Shi
{"title":"Superamphiphilic aerogels with 2D lamellar structure of gelatin-tuned 3D supramolecular network of collagen fibers for high-performance separation of surfactant-stabilized emulsified oily wastewater","authors":"Honglian Liu,&nbsp;Hanzhong Xiao,&nbsp;Baicun Hao,&nbsp;Wan Zheng,&nbsp;Yujia Wang,&nbsp;Xin Huang,&nbsp;Bi Shi","doi":"10.1186/s42825-024-00166-6","DOIUrl":"10.1186/s42825-024-00166-6","url":null,"abstract":"<div><p>Superwetting aerogel is a promising alternative for the remediation of emulsified oily wastewater for its high porosity combined with extreme wettability enabled high separation performances to emulsion wastewater. However, it remains challenging for superwetting aerogels to accomplish high-performance dual separation to surfactant-stabilized oil-in-water (O/W) and water-in-oil (W/O) emulsions with high stability. Herein, an environmentally benign superamphiphilic composite aerogel was prepared by a green synthesis route that relied on the utilization of natural amphiphilic biomass. Collagen fibers (CFs) were utilized to construct the three-dimensional (3D) supramolecular skeleton of aerogel to provide high storage capacity of water/oil and outstanding capillary effect to boost the mass transfer. The two-dimensional (2D) lamellar structure of gelatin (Gel) was further grown on the skeleton of CFs aerogel to play the role for simultaneously enhanced demulsifying capability and spreading of emulsions. The as-prepared superamphiphilic aerogel enabled the separation of highly stable surfactant-stabilized O/W and W/O emulsions with high separation efficiency and flux. Excellent recycling performances and anti-fouling performance were also confirmed. Our investigations therefore demonstrated that the structural engineering of superamphiphilic aerogel is a promising way to realize high-performance dual separation of surfactant-stabilized O/W and W/O emulsion wastewater.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00166-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141886306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioactive poly(ethylene glycol)-chondroitin sulfate-triple helical recombinant collagen hydrogel for enhanced cranial defect repair 生物活性聚乙二醇-硫酸软骨素-三重螺旋重组胶原水凝胶用于增强颅骨缺损修复效果
Journal of Leather Science and Engineering Pub Date : 2024-08-01 DOI: 10.1186/s42825-024-00168-4
Lili Wang, Shanshan Zhang, Fan Yang, Xian Chen, Huixia He, Zaiman Liu, Jianxi Xiao
{"title":"Bioactive poly(ethylene glycol)-chondroitin sulfate-triple helical recombinant collagen hydrogel for enhanced cranial defect repair","authors":"Lili Wang,&nbsp;Shanshan Zhang,&nbsp;Fan Yang,&nbsp;Xian Chen,&nbsp;Huixia He,&nbsp;Zaiman Liu,&nbsp;Jianxi Xiao","doi":"10.1186/s42825-024-00168-4","DOIUrl":"10.1186/s42825-024-00168-4","url":null,"abstract":"<div><p>The reconstruction of critical-size calvarial defects remains a fundamental challenge. Recombinant collagen has gained significant attention in bone tissue engineering owing to its remarkable bioactivity and non-immunogenicity. Herein, we have for the first time developed a bioactive poly(ethylene glycol)-chondroitin sulfate-triple helical recombinant collagen (PEG-ChS-THRC) hydrogel for enhanced bone regeneration in cranial defects. A simple and mild crosslinking reaction of two-arm polyethylene glycol active ester (NHS-PEG-NHS), adipic dihydrazide modified chondroitin sulfate (ChS-ADH) and triple helical recombinant collagen (THRC) leads to the formation of the PEG-ChS-THRC hydrogel. The hydrogel demonstrates interconnected porous structures, enhanced mechanical strength, diminished swelling ratios and adjustable biodegradability. It possesses exceptional biocompatibility and bioactivity, significantly facilitating cell proliferation, adhesion, migration, and osteogenic differentiation of BMSCs. Micro-computed tomography (micro-CT), magnetic resonance imaging (MRI) and histological characterization of rat models with critical-size cranial defects have consistently demonstrated that the PEG-ChS-THRC hydrogel significantly promotes bone tissues regeneration. The innovative bioactive scaffold provides a remarkably improved remedy for critical-size cranial defects, holding greatly promising applications in the fields of bone tissue regeneration.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00168-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141886305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amphiphilic block and random copolymers: aggregation and hydrophobic modification on metal-free tanned collagen fibers 两亲嵌段共聚物和无规共聚物:无金属鞣革胶原纤维上的聚集和疏水改性
Journal of Leather Science and Engineering Pub Date : 2024-07-03 DOI: 10.1186/s42825-024-00163-9
Yudan Yi, Xinxin Fan, Qijun Li, Ya-nan Wang
{"title":"Amphiphilic block and random copolymers: aggregation and hydrophobic modification on metal-free tanned collagen fibers","authors":"Yudan Yi,&nbsp;Xinxin Fan,&nbsp;Qijun Li,&nbsp;Ya-nan Wang","doi":"10.1186/s42825-024-00163-9","DOIUrl":"10.1186/s42825-024-00163-9","url":null,"abstract":"<div><p>Hydrophobicity enhancement of metal-free leather, which is crucial for improving its comprehensive performance, can be achieved by using amphiphilic copolymer retanning agents. However, the relationship between the sequential structure and the hydrophobic modification effect of amphiphilic copolymers remains unclear. Herein, an amphiphilic block copolymer was synthesized using stearyl methacrylate and 2-(dimethylamino)ethyl methacrylate via atom transfer radical polymerization, and the corresponding random copolymer with similar monomer compositions and molecular weights was prepared for comparison. The aggregation behavior of block and random copolymers was investigated. DLS and TEM results indicate that the block copolymer exhibits a larger aggregate size than the corresponding random copolymer. Molecular dynamics simulations suggest that the block copolymer aggregate exhibit a thicker hydrophilic shell and more concentrated distribution of cationic DMA block than the random copolymer aggregate. Subsequently, the block and random copolymers were used for the hydrophobic modification of metal-free tanned collagen fibers (CFs). The block copolymer shows superior binding capacity to CFs than the random one because of its larger size and more concentrated charge distribution. Hence, the block copolymer can form a dense and uniform hydrophobic film on the surface of collagen fibrils and endow CFs with higher hydrophobicity than the random one. This work provides theoretical guidance for modulating the hydrophobicity of CFs by tailoring the sequential structure of amphiphilic copolymers, which is expected to inspire the manufacturing of high-performance metal-free leather.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00163-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141495484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On-demand engineered double-network gelatin/silicate composited hydrogels with enhanced wet adhesion and stable release of bioactive ion for promoting wound healing 按需设计的明胶/硅酸盐双网复合水凝胶具有更强的湿粘附性和生物活性离子的稳定释放,可促进伤口愈合
Journal of Leather Science and Engineering Pub Date : 2024-07-02 DOI: 10.1186/s42825-024-00161-x
Xiaomin Luo, Lufeng Ji, Fen Ao, Chen Yang, Jiang Chang, Changyu Yin, Huijun Ren, Ming Teng, Liuying Li, Xinhua Liu
{"title":"On-demand engineered double-network gelatin/silicate composited hydrogels with enhanced wet adhesion and stable release of bioactive ion for promoting wound healing","authors":"Xiaomin Luo,&nbsp;Lufeng Ji,&nbsp;Fen Ao,&nbsp;Chen Yang,&nbsp;Jiang Chang,&nbsp;Changyu Yin,&nbsp;Huijun Ren,&nbsp;Ming Teng,&nbsp;Liuying Li,&nbsp;Xinhua Liu","doi":"10.1186/s42825-024-00161-x","DOIUrl":"10.1186/s42825-024-00161-x","url":null,"abstract":"<div><p>Silicate bioceramics have demonstrated great potential in hydrogel dressings for wound healing due to their special origins of promoting endothelial cell angiogenesis and inhibiting apoptosis of cardiomyocyte. However, there are still some deficiencies, such as insufficient biological activity, instability of silicate ion release, and lower wet adhesion on wounds with tissue exudate, limiting their further clinical applications. Herein, inspired by mussels, a multifunctional double-network hydrogel (FS/PAM-Gel-PDA) wound dressing composited gelatin with silicate ceramic powder with satisfactory wet adhesion, stable release of bioactive ions, hemostasis, and the ability of promoting vascular regeneration was engineered through specifically grafting dopamine to gelatin and introducing ferrous silicate ceramic powder into the hydrogel. The comprehensive experimental results substantiate that the FS/PAM-Gel-PDA has wet-adhesion strength of up to 21.78 kPa, and remains stably adherent to porcine myocardial tissues intuitively after bending, twisting, soaking in water, and stretching. The test results of ion release behavior in vitro show that the oxidation and agglomeration of ferrous silicate ceramic powder can be effectively inhibited by using dopamine to form an antioxidant layer on the surface of ceramic powder, and thus, the stable release of Fe<sup>2+</sup> and SiO<sub>4</sub>\u0000<sup>4−</sup> effective ions can be realized. The animal experiment exhibits that FS/PAM-Gel-PDA can achieve rapid hemostasis in the lethal liver defect model. Meanwhile, the FS/PAM-Gel-PDA reveals the remarkable ability to promote wound healing in a full-thickness skin injury model, which can obviously accelerate skin re-epithelialization. To sum up, the FS/PAM-Gel-PDA has excellent wet adhesion and stable release of active ions to accelerate angiogenesis, which shows great potential in promoting wound healing.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00161-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141495495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of mADM-collagen wound dressings for mimicking native skin architecture to enhance skin wound healing 开发 mADM-胶原蛋白伤口敷料,用于模拟原生皮肤结构,促进皮肤伤口愈合
Journal of Leather Science and Engineering Pub Date : 2024-07-01 DOI: 10.1186/s42825-024-00159-5
Xiang Wang, Yujia Jiang, Xiaoqin Sun, Chongxia Yue, Zhengyong Li, Yao Wu
{"title":"Development of mADM-collagen wound dressings for mimicking native skin architecture to enhance skin wound healing","authors":"Xiang Wang,&nbsp;Yujia Jiang,&nbsp;Xiaoqin Sun,&nbsp;Chongxia Yue,&nbsp;Zhengyong Li,&nbsp;Yao Wu","doi":"10.1186/s42825-024-00159-5","DOIUrl":"10.1186/s42825-024-00159-5","url":null,"abstract":"<div><p>Acellular dermal matrix (ADM) is one of the most promising scaffold materials due to its ability to retain natural extracellular matrix structure. Micronized acellular dermal matrix (mADM) was prepared with no intact cell nuclei and preserved growth factors by High Hydrostatic Pressure (HHP) approach. And mADM-collagen wound dressings were developed with different proportion of type I collagen and recombinant humanized type III collagen. The porous structure of the mADM-collagen wound dressings made them a good candidate for preventing excessive fluid accumulation, while the collagens with gel-like texture combined with mADM powder to form pasty texture wound dressing, which preserving the moisture at the wound site. Moreover, the paste texture of the mADM-collagen wound dressing was easy to reshape to conform any wound shapes and body contours. Furthermore, the resulted mADM-collagen wound dressings showed good biocompatibility by supporting fibroblasts adhesion and proliferation in vitro. Subsequently, a murine model of full-thickness skin wounds was employed to assess its effects on wound healing. Notably, mADM-75% Col-I exhibited superior effects throughout the wound healing process, specifically it promoted neovascularization, skin appendage growth and new skin regeneration. This formulation closely mimicked the collagen ratio found in healthy skin, facilitating the favorable wound repair. These results indicated the superior performance of this mADM-collagen wound dressing providing an optimal environment for wound healing.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00159-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141475044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of tannery wastes on anaerobic co-digestion: enhancing biogas production and process efficiency 制革废料对厌氧协同消化的影响:提高沼气产量和工艺效率
Journal of Leather Science and Engineering Pub Date : 2024-06-02 DOI: 10.1186/s42825-024-00162-w
Fetra J. Andriamanohiarisoamanana, Mohamed Farghali, Israa M. A. Mohamed, Gen Yoshida, Kazuya Shiota, Ikko Ihara
{"title":"Impact of tannery wastes on anaerobic co-digestion: enhancing biogas production and process efficiency","authors":"Fetra J. Andriamanohiarisoamanana,&nbsp;Mohamed Farghali,&nbsp;Israa M. A. Mohamed,&nbsp;Gen Yoshida,&nbsp;Kazuya Shiota,&nbsp;Ikko Ihara","doi":"10.1186/s42825-024-00162-w","DOIUrl":"10.1186/s42825-024-00162-w","url":null,"abstract":"<div><p>The study investigates the potential of anaerobic co-digestion (AcoD) as a sustainable solution for managing putrescible organic waste generated by leather processing. Three experiments were conducted to assess the impact of various tannery wastes, pretreatment methods, and waste combinations on methane production. Experiment 1 demonstrated that co-digesting tannery wastewater primary sludge (TWPS) and fleshings significantly increased methane yield compared to digesting TWPS alone, though the addition of chromium- and vegetable-tanned leather wastes decreased yield. Experiment 2 explored TWPS pretreatment methods and found that ultrasonic pretreatment increased soluble chemical oxygen demand (SCOD) but did not significantly improve methane yield, suggesting that pretreatment may not be necessary. Experiment 3 revealed that increasing the proportion of fleshings to TWPS resulted in higher methane yield, ranging from 226.52 mL/gVS with 6% fleshings to 395.71 mL/gVS and 538.34 mL/gVS with 12% and 20% of fleshings, respectively. Additionally, this increase in fleshings also led to a reduction in digester volume. These findings highlight the importance of AcoD in addressing both environmental and economic challenges in the leather industry.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":640,"journal":{"name":"Journal of Leather Science and Engineering","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://JLSE.SpringerOpen.com/counter/pdf/10.1186/s42825-024-00162-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141187286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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