Analyst最新文献_第10页

An electrochemiluminescent sensor based on ZnPTC@MoS₂ nanocomposite for sensitive determination of trilobatin. 基于ZnPTC@MoS2纳米复合材料的电化学发光传感器用于三叶虫素的灵敏测定。

IF 3.6 3区化学

Analyst Pub Date : 2026-09-16 DOI: 10.1039/d6an00682e

Xiaohui Chen, Xue Mei, Wenchang Wang, Qingyi Li, Zhidong Chen

{"title":"An electrochemiluminescent sensor based on ZnPTC@MoS2 nanocomposite for sensitive determination of trilobatin.","authors":"Xiaohui Chen, Xue Mei, Wenchang Wang, Qingyi Li, Zhidong Chen","doi":"10.1039/d6an00682e","DOIUrl":"10.1039/d6an00682e","url":null,"abstract":"In this work, a sensitive electrochemiluminescence (ECL) sensing platform was developed for the determination of trilobatin (Tri) using a ZnPTC@MoS2-modified glassy carbon electrode. In this sensing interface, ZnPTC acts as both an intrinsically ECL-active metal-organic framework and a structural scaffold, while MoS2 nanosheets promote interfacial electron transfer and facilitate the electroreduction of persulfate. The synergistic integration of ZnPTC and MoS2 effectively alleviates the restacking of MoS2 nanosheets, improves charge-transfer kinetics, and significantly enhances the ECL response of the composite. Under the optimized experimental conditions, the change in ECL intensity showed a good linear relationship with the logarithm of Tri concentration over the range of 5.0 × 10-8-1.0 × 10-3 M, with a detection limit of 5.6 × 10-9 M. The proposed ECL sensor exhibited good selectivity, reproducibility, operational stability, and long-term stability. Moreover, the method was successfully applied to the determination of Tri in real samples, affording recoveries of 98.98-103.66% with relative standard deviations below 2.50%. These results demonstrate that the ZnPTC@MoS2-based ECL platform provides a promising analytical strategy for sensitive Tri determination in practical samples.","PeriodicalId":63,"journal":{"name":"Analyst","volume":" ","pages":"5278-5285"},"PeriodicalIF":3.6,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148596618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Cys-responsive fluorescent sensor for monitoring Cys levels in a polycystic ovary syndrome mouse model. 一种用于监测多囊卵巢综合征小鼠模型中Cys反应性荧光传感器。

IF 3.6 3区化学

Analyst Pub Date : 2026-09-16 DOI: 10.1039/d6an00854b

Liu-Yan Qian, Xin-Meng Yu, Miao-Yan Wang, Kai Wang, Hao-Xiang Jiang, Lu Qiu, Jie Liu, Yu-Hua Chen

{"title":"A Cys-responsive fluorescent sensor for monitoring Cys levels in a polycystic ovary syndrome mouse model.","authors":"Liu-Yan Qian, Xin-Meng Yu, Miao-Yan Wang, Kai Wang, Hao-Xiang Jiang, Lu Qiu, Jie Liu, Yu-Hua Chen","doi":"10.1039/d6an00854b","DOIUrl":"10.1039/d6an00854b","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is a prevalent endocrine-metabolic disorder among women of reproductive age and is closely associated with oxidative stress, redox imbalance, and metabolic dysfunction. Accumulating evidence indicates that elevated cysteine (Cys) levels are involved in PCOS-related pathological processes and may reflect disease-associated metabolic alterations. Herein, we developed HD-Cys, a hemicyanine-based fluorescent molecular probe for sensitive detection of Cys. HD-Cys responds to Cys through a specific activation mechanism, generating a pronounced fluorescence enhancement with a low detection limit of 0.02 μM. Its biological applicability was investigated using cellular imaging, where HD-Cys enabled visualization of endogenous Cys-associated fluorescence changes. More importantly, serum analysis demonstrated that HD-Cys clearly differentiated PCOS-model samples from healthy controls, with markedly enhanced fluorescence signals consistent with elevated Cys levels under PCOS pathological conditions. Benefiting from its high chemical specificity, favorable stability, and good biocompatibility, HD-Cys provides a useful molecular tool for assessing Cys dysregulation in PCOS and holds potential for early disease evaluation and treatment-response monitoring.","PeriodicalId":63,"journal":{"name":"Analyst","volume":" ","pages":"5387-5398"},"PeriodicalIF":3.6,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148704732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microbarrier-confined droplet bilayers on PEDOT:PSS enable high-resistance, dynamically addressable bioelectronic interfaces PEDOT:PSS上的微障限制液滴双层实现了高电阻、动态寻址的生物电子界面

IF 4.2 3区化学

Analyst Pub Date : 2026-09-15 DOI: 10.1039/d6an00737f

Essraa A Hussein,Beliz Utebay,Emily A Schafer,Neha Kamat,Jonathan Rivnay,Nickolay V Lavrik,Stephen Andrew Sarles

引用次数: 0

Progress in electrochemical detection of levofloxacin and norfloxacin antibiotics: Advanced functional materials, analytical performance, challenges, and perspectives 左氧氟沙星和诺氟沙星抗生素电化学检测研究进展：先进功能材料、分析性能、挑战与展望

IF 4.2 3区化学

Analyst Pub Date : 2026-09-14 DOI: 10.1039/d6an00953k

Khursheed Ahmad,Vinay Kumar Tripathi,Rohit Kumar Singh Gautam,Vivek Mani Tripathi,Rajkumar Chellakannu,Tae Hwan Oh

{"title":"Progress in electrochemical detection of levofloxacin and norfloxacin antibiotics: Advanced functional materials, analytical performance, challenges, and perspectives","authors":"Khursheed Ahmad,Vinay Kumar Tripathi,Rohit Kumar Singh Gautam,Vivek Mani Tripathi,Rajkumar Chellakannu,Tae Hwan Oh","doi":"10.1039/d6an00953k","DOIUrl":"https://doi.org/10.1039/d6an00953k","url":null,"abstract":"In recent years, electrochemical sensing of fluoroquinolone antibiotics has attracted significant research interest. However, the practical relevance of many reported sensors remains uncertain because their performance is often evaluated primarily on the basis of detection limits. This review critically evaluates reported sensing systems for levofloxacin (LFN) and norfloxacin (NOR), two structurally related antibiotics that provide a stringent basis for assessing both signal amplification and molecular selectivity. Direct voltammetric detection, electro-catalytic electrodes, molecularly imprinted interfaces, biosensors, ion-selective membranes, and ion transfer across electrified liquid-liquid interfaces have been critically assessed using a unified analytical framework. Metal oxides, carbon-based materials, polymers, MXenes, porous frameworks, and hybrid composites are further examined in terms of their specific roles in molecular recognition, charge transfer, and signal generation. The review critically evaluates selectivity, analytical performance in real samples, reproducibility, operational stability, fouling resistance, fabrication complexity, and compatibility with disposable sensing systems. It is also observed that more complex sensor designs do not always improve analytical performance. In many cases, simpler electrodes provide a better balance of sensitivity, reliability, and ease of fabrication. The practical use of electrochemical sensors for LFN and NOR remains restricted by limited batch-to-batch testing, inadequate comparison with established reference methods, and insufficient evaluation using incurred samples. Future studies may focus on simpler and more reproducible sensing systems that can provide reliable results in routine LFN and NOR analysis. Finally, challenges and future research directions are discussed.","PeriodicalId":63,"journal":{"name":"Analyst","volume":"47 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Twisted intramolecular charge transfer emission turn-on sensing towards picric acid 扭曲分子内电荷转移发射对苦味酸的开启感测

IF 4.2 3区化学

Analyst Pub Date : 2026-09-14 DOI: 10.1039/d6an00740f

Arup Das Kanungo,G. Krishnamoorthy

引用次数: 0

Infrared spectroscopy with statistical analysis and machine learning for cancer risk assessment in inflammatory bowel disease patients 红外光谱统计分析和机器学习在炎症性肠病患者癌症风险评估中的应用

IF 4.2 3区化学

Analyst Pub Date : 2026-09-14 DOI: 10.1039/d6an00649c

Eric Kumi-Barimah,Raneem Toman,Animesh Jha,Sharib Ali,Venkataraman Subramanian

{"title":"Infrared spectroscopy with statistical analysis and machine learning for cancer risk assessment in inflammatory bowel disease patients","authors":"Eric Kumi-Barimah,Raneem Toman,Animesh Jha,Sharib Ali,Venkataraman Subramanian","doi":"10.1039/d6an00649c","DOIUrl":"https://doi.org/10.1039/d6an00649c","url":null,"abstract":"Patients with inflammatory bowel disease (IBD) undergo regular colonoscopic surveillance due to their elevated risk of developing colorectal cancer (CRC). However, current clinical, endoscopic and histopathological risk stratification methods can be limited in sensitivity and objectivity, highlighting the need for complementary molecular approaches. In this study, Attenuated Total Reflectance–Fourier Transform Infrared Spectroscopy (ATR-FTIR) was used to acquire mid-infrared (MIR) spectra from IBD-associated endoscopic biopsy samples (30 patients analysed; 10 who developed dysplastic pre-cancerous lesions and 20 who did not during long-term follow-up). Samples were stratified according to baseline clinical CRC risk (high/low) and subsequent pre-cancerous lesion development, enabling assessment of molecular signatures associated with future cancer risk rather than solely current disease status. Spectral variations were analysed using chemometric methods and machine learning classifiers. Principal component analysis (PCA) was performed to evaluate spectral separation, with the first three components (PC1, PC2 and PC3) accounting for 76.8%, 19.2% and 2.7% of the total variance, respectively. Hierarchical clustering analysis (HCA) further explored similarity patterns across defined spectral regions. Among the evaluated models, PLS-based classifiers achieved a balanced accuracy of 0.61–0.70 under repeated nested cross-validation; however, a permutation test indicated that this performance was not significantly above chance (p = 0.51), and no classifier significantly outperformed another. These findings indicate that ATR-FTIR-derived molecular fingerprints, particularly in the lipid-associated 2950–3030 cm−1 region, carry information associated with long-term CRC risk in IBD patients, but that a definitive classifier cannot be established from a cohort of this size; the approach is presented as a complementary, hypothesis-generating tool to conventional surveillance strategies.","PeriodicalId":63,"journal":{"name":"Analyst","volume":"2 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ternary PANI/SnO–TiO heterostructure interfaces for the rapid and selective electrochemical detection of 8-hydroxyquinoline 三元聚苯胺/ SnO-TiO异质结构界面用于8-羟基喹啉的快速选择性电化学检测

IF 4.2 3区化学

Analyst Pub Date : 2026-09-14 DOI: 10.1039/d6an00662k

Samuel Chufamo Jikamo,P. Shyamala,Singupilla Sai Supriya,M. Ravi Chandra

{"title":"Ternary PANI/SnO–TiO heterostructure interfaces for the rapid and selective electrochemical detection of 8-hydroxyquinoline","authors":"Samuel Chufamo Jikamo,P. Shyamala,Singupilla Sai Supriya,M. Ravi Chandra","doi":"10.1039/d6an00662k","DOIUrl":"https://doi.org/10.1039/d6an00662k","url":null,"abstract":"A ternary PANI/SnO2–TiO2 heterostructure nanocomposite was fabricated for the electrochemical detection of 8-hydroxyquinoline (8-HQ) through a combined sol–gel and in situ polymerization approach. Initially, SnO2–TiO2 hybrid nanocomposites were synthesized via the sol–gel method, followed by the in situ polymerization of aniline monomers on the hybrid surface to construct a ternary heterostructure for characterization. For electrochemical sensing applications, PANI/SnO2–TiO2 heterostructured films were fabricated on glassy carbon electrodes (GCE) through the electrochemical polymerization of aniline on pre-modified SnO2–TiO2/GCE. The structural, morphological, compositional, and electrochemical properties of the fabricated nanocomposites were systematically characterized using PXRD, UV-Vis DRS, VB-XPS, FESEM-EDS, HRTEM, BET, FTIR spectroscopy, CV, EIS, and chronoamperometry. BET analysis revealed that PANI/SnO2–TiO2 exhibited a significantly higher specific surface area (101.70 m2 g−1) than PANI/TiO2 (35.30 m2 g−1) and pristine PANI (18.70 m2 g−1), indicating enhanced electroactive surface area and abundant active sites. The developed PANI/SnO2–TiO2/GCE sensor exhibited excellent sensing performance toward 8-HQ, with a high sensitivity (224.44 μA × 10−7 M−1 cm−2), low detection limit (0.58 × 10−8 M), and wide linear range (0.1–0.8 × 10−7 M), as determined using LSV. Furthermore, remarkable selectivity, durability, reproducibility, and successful applicability for wastewater sample analysis were observed, demonstrating potential for environmental monitoring applications.","PeriodicalId":63,"journal":{"name":"Analyst","volume":"25 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitive Fluorescent Biosensors Based on Cascade Signal Amplification strategy and Stimuli-Responsive Hydrogel for the Detection of p53 Gene 基于级联信号放大策略和刺激反应水凝胶的敏感荧光生物传感器检测p53基因

IF 4.2 3区化学

Analyst Pub Date : 2026-09-09 DOI: 10.1039/d6an00852f

Xiaoya Wu,Qiuhang Chen,Jianjun Zheng,Yuling Gao,Yingjuan Cao,Zhixin Li,Zhiqin Chen

{"title":"Sensitive Fluorescent Biosensors Based on Cascade Signal Amplification strategy and Stimuli-Responsive Hydrogel for the Detection of p53 Gene","authors":"Xiaoya Wu,Qiuhang Chen,Jianjun Zheng,Yuling Gao,Yingjuan Cao,Zhixin Li,Zhiqin Chen","doi":"10.1039/d6an00852f","DOIUrl":"https://doi.org/10.1039/d6an00852f","url":null,"abstract":"As a key tumor suppressor gene, the mutation and abnormal expression of p53 are closely correlated with tumor occurrence and progression, serving as an important biomarker for early tumor diagnosis. Herein, a novel fluorescent biosensor based on a Cas12a/alkaline phosphatase (ALP) cascade signal amplification strategy and stimuli-responsive DNA hydrogels was constructed for sensitive quantification of p53 gene. High-stability carbon dots/silica (CDs/SiO2) composites were adopted as excellent fluorescent signal sensing elements with outstanding optical stability in complex environments. ALP-encapsulated hyaluronic acid (HA)-DNA hydrogel was prepared as a stimuli-responsive recognition. The specific binding of target p53 gene activates the trans-cleavage activity of CRISPR/Cas12a, which cleaves the HA-DNA hydrogel structure and triggers the release of ALP. The released ALP further catalyzes the hydrolysis of p-nitrophenyl phosphate (PNPP) substrate to generate p-nitrophenol (PNP). The generated PNP quenches the fluorescence of CDs/SiO2 composites through inner filter effect (IFE), and the fluorescence quenching value is positively correlated with p53 gene concentration. The biosensor exhibited a favorable linear detection range of 1 pM–100 nM with a low detection limit of 0.074 pM. The proposed strategy eliminates cumbersome pre-amplification procedures for nucleic acids, provides a simple, sensitive and reliable new approach for p53 gene detection in complex biological samples, and exhibits great potential in early tumor auxiliary diagnosis and clinical biological analysis.","PeriodicalId":63,"journal":{"name":"Analyst","volume":"31 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PNA-assisted magnetic bead-confined CbAgo-CRISPR/Cas12a cascade for amplification-free detection of Mycobacterium avium subsp. paratuberculosis F57 DNA pna辅助磁珠限制CbAgo-CRISPR/Cas12a级联无扩增检测鸟分枝杆菌亚种副结核菌F57 DNA

IF 4.2 3区化学

Analyst Pub Date : 2026-09-09 DOI: 10.1039/d6an00843g

Shouyan Wu,Xiumei Mu,Zhijuan Wu

{"title":"PNA-assisted magnetic bead-confined CbAgo-CRISPR/Cas12a cascade for amplification-free detection of Mycobacterium avium subsp. paratuberculosis F57 DNA","authors":"Shouyan Wu,Xiumei Mu,Zhijuan Wu","doi":"10.1039/d6an00843g","DOIUrl":"https://doi.org/10.1039/d6an00843g","url":null,"abstract":"Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne’s disease in ruminants, has attracted increasing attention because of its potential zoonotic relevance. Sensitive molecular detection of MAP typically relies on nucleic acid amplification to overcome low pathogen abundance; however, amplification may generate nonspecific products and false-positive results. Here, targeting MAP-specific F57 double-stranded DNA, we developed a peptide nucleic acid (PNA)-assisted, magnetic bead-confined Clostridium butyricum Argonaute (CbAgo)-CRISPR/Cas12a cascade electrochemiluminescent (ECL) biosensing platform for amplification-free MAP detection. The platform comprises two functional magnetic-bead microreactors. In the PNA-CbAgo cleavage microreactor (PCCM), PNA and CbAgo/gDNA complexes are co-immobilized on magnetic beads. PNA-mediated local duplex opening facilitates CbAgo cleavage and generation of target-derived DNA fragments (tDNA). In the CRISPR/Cas12a-Ru ECL signaling microreactor (CREM), CRISPR/Cas12a-crRNA complexes and Ru-labeled ssDNA reporters are co-confined on magnetic beads. The generated tDNA activates localized CRISPR/Cas12a trans-cleavage, leading to reporter release and a target-dependent decrease in ECL intensity. Mechanistic studies showed that PCCM enhances tDNA generation through PNA-assisted duplex opening and bead interfacial confinement, whereas CREM enables efficient ECL transduction through localized CRISPR/Cas12a-crRNA-reporter coupling. Under optimized conditions, the platform achieved a detection limit of 34.1 CFU mL−1, exhibited good specificity, agreed well with qPCR in spiked bovine fecal samples, and demonstrated robust overall performance in complex matrices. This work provides an amplification-free ECL strategy for sensitive and specific MAP detection and highlights the potential of bead-confined programmable nuclease cascades for pathogen nucleic acid analysis.","PeriodicalId":63,"journal":{"name":"Analyst","volume":"45 4 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Spatial-Temporal Deep Learning Method for Heavy Metal Ion Detection 重金属离子检测的时空深度学习方法

IF 4.2 3区化学

Analyst Pub Date : 2026-09-09 DOI: 10.1039/d6an00705h

Jinlong Shi,yunpeng gao,Yiwei Cong,Yunbo Shi,Mingjun Zhou,Yinsheng Chen

{"title":"A Spatial-Temporal Deep Learning Method for Heavy Metal Ion Detection","authors":"Jinlong Shi,yunpeng gao,Yiwei Cong,Yunbo Shi,Mingjun Zhou,Yinsheng Chen","doi":"10.1039/d6an00705h","DOIUrl":"https://doi.org/10.1039/d6an00705h","url":null,"abstract":"Heavy metal ions such as Cd2+, Pb2+, and Cu2+ pose severe threats to public health and aquatic ecosystems. Traditional electrochemical detection faces significant challenges including high sample consumption, manual intervention, and difficulties parsing overlapping signals. To address these issues we propose an intelligent metal ion detection platform integrating a microfluidic chip with a deep learning framework. The microfluidic system enables precise droplet manipulation for automated signal acquisition utilizing minimal sample volumes. To overcome traditional limitations in direct feature extraction we developed a multidimensional relational feature enhancement architecture. Specifically we propose a multitask framework prioritizing the integration of a Convolutional Neural Network and a Temporal Convolutional Network to form the primary C-TCN model. This effectively models sequence dependencies to simultaneously achieve accurate ion classification and concentration regression. Experimental results show the optimal C-TCN model increased classification accuracy by 25.9% compared to the unmodified CNN, successfully outperforming alternative LSTM variants. Furthermore, the C-TCN framework significantly outperforms traditional machine learning methods across all critical evaluation metrics including F1 score, AUC, and regression error. These results demonstrate that the synergistic combination of spatial purification and temporal convolutional tracking provides a highly stable and robust paradigm for intelligent electrochemical sensing.","PeriodicalId":63,"journal":{"name":"Analyst","volume":"31 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0