临床病例讨论杂志(英文版)最新文献

{"title":"Diagnostic value of VCG combined with CDE for acute inferior MI culprit vessel","authors":"Zhi-hui Zhao, Li Jiang","doi":"10.5430/DCC.V6N1P7","DOIUrl":"https://doi.org/10.5430/DCC.V6N1P7","url":null,"abstract":"Objective: To explore the diagnostic value of vectorcardiography (VCG) combined with color Doppler echocardiography (CDE) for acute inferior myocardial infarction (MI) culprit vessel.Methods: A total of 82 patients who had been clinically diagnosed as acute inferior MI and had received coronary arteriography (CAG) were selected as research objects. They received bedside VCG and CDE examinations after admission. Their culprit vessels were analyzed and compared with CAG results to evaluate the diagnostic efficiency.Results: The detection rate of acute inferior MI culprit vessel by VCG combined with CDE was 76.83%, including 18 left circumflex (LCX) branches and 45 right coronary arteries (RCA). The lower left constituent ratio of LCX was 61.11%, which was significantly higher than 20.00% in RCA (p < .05); the lower right constituent ratio of RCA was 71.11%, which was much higher than 11.11% in LCX (p < .05); the sensitivity and the accuracy of RCA culprit vessel judged with frontal plane ST-vector pointing to the lower right quadrant were 71.11% and 53.33% respectively; the diagnostic efficiency of LCX culprit vessel judged with frontal plane ST-vector pointing to the lower left quadrant was 61.11% and 50.00% respectively. The maximum amplitude of the frontal plane in LCX culprit vessel was significantly lower than that in RCA culprit vessel; and the frontal plane vector angle in LCX was significantly greater than that in RCA culprit vessel (p < 0.05).Conclusions: VCG combined with CDE can effectively diagnose acute inferior MI. It has a good diagnostic efficiency by judging culprit vessels according to the frontal plane ST-vector direction.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81660859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds","authors":"Zhihui Hou, Mingjuan Gu","doi":"10.5430/DCC.V6N1P11","DOIUrl":"https://doi.org/10.5430/DCC.V6N1P11","url":null,"abstract":"Objective: To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds.Methods: During March of 2015 to April of 2018, 52 cases of patients with deep chronic refractory wounds were selected as research objects. They were divided into the control group and the treatment group by use of the random number table method, with 26 cases in each group. Among them, the control group was given conventional debridement combined with flap reconstruction, and the treatment group was treated with modified closed negative pressure suction technique combined with flap transplantation to observe the clinical effect.Results: (1) According to the analysis on the effect of flap transplantation, the excellent and good rate of the treatment group was 92.3%, and in the control group, it was 76.9% (p < .05). (2) According to the statistics, the incidence of complications in the treatment group was lower than that in the control group (p < .05).Conclusions: Modified closed negative pressure suction technique combined with flap transplantation has a good effect on the treatment of deep chronic refractory wounds with fewer complications.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82982545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey data analysis of the related risk factors of echinococcosis in Inner Mongolia of China and Mongolia","authors":"Sheng-bin Zhang, Zhelin Yun, E Erdengsuhe, Baoqin Liu","doi":"10.5430/DCC.V6N1P17","DOIUrl":"https://doi.org/10.5430/DCC.V6N1P17","url":null,"abstract":"Objective: The aim of the study is to analyze the risk factors of hepatic echinococcosis in mass epidemiological studies in Inner Mongolia of China and Mongolia and provide a basis for related authorities to make appropriate preventive measures.Methods: Eight areas in Inner Mongolia and Zamyn-Üüd region of Mongolia were selected as epidemiological fields. By distributing epidemiological questionnaires to local residents and performing serological examinations and abdominal ultrasound examinations, the data results were collected and analyzed to obtain the risk factors.Results: In this research, there were 7,373 cases of valid data in the area of Inner Mongolia and 1,500 cases in the area of Mongolia. The mean age of the whole survey samples was 52.86 ± 13.90, and the ratio of the female (58.35%) was much higher than that of the male (41.65%). Both univariate analysis and multivariate analysis in this study showed that the female (14.7%) had a higher risk of hepatic echinococcosis than the male (10.9%). From the perspective of profession, children, educators and medical personnel had a lower incidence, herdsmen had the highest positive rate of the disease (15.8%). Living in pastoral areas, having been to pastoral areas, eating uncooked food and drinking unboiled water, raising dogs and surrounding activities of foxes and voles can also increase the risk of positivity.Conclusions: Our findings demonstrate that the most important risk factor of hepatic echinoccosis is unhealthy lifestyles and customs in farmers and herdsmen. It is possible to provide a basis for related authorities to make effective protective measures aiming at hepatic echinococcosis.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78486247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism of apoptosis induced by Mcl-1 inhibitor UMI-77 on gallbladder carcinoma GBC-SD cells","authors":"Sheng-bin Zhang, Baoqin Liu, C. Dong, Bing Li","doi":"10.5430/DCC.V6N1P1","DOIUrl":"https://doi.org/10.5430/DCC.V6N1P1","url":null,"abstract":"Objective: To investigate the mechanism of apoptosis induced by myeloid cell leukemia-1 (Mcl-1) inhibitor UMI-77 on gallbladder carcinoma GBC-SD cells.Methods: GBC-SD cells were treated with different concentrations of UMI-77. GBC-SD cell proliferation and apoptosis were detected by MTT assay and Annexin V/PI. The expressions of Mcl-1, Bcl-2, Bcl-xL, Bax, Bak, cleaved-caspase 9, cleaved-caspase 3 and cleaved-PARP proteins in GBC-SD cells treated with UMI-77 were detected by Western blotting.Results: The results of MTT showed that different concentrations of UMI-77 had different inhibitory effects on cell proliferation of GBC-SD cells in a dose-dependent and time-dependent manner. Annexin V/PI results showed that the apoptosis rate was increasing gradually with the increase of UMI-77 concentration in a dose-dependent manner. Western blotting results showed that the expression of anti-apoptotic protein Mcl-1 was significantly decreased (p < .05), and the expressions of Bax and Bak proteins were significantly increased respectively (p < .05), but there were no significant changes in the expressions of Bcl-2 and Bcl-xL proteins, and the expression levels of cleaved-caspase 9, cleaved-caspase 3 and cleaved-PARP proteins were significantly increased (p < .05) in 24 h after GBC-SD cells were treated with 10 μmol/L of UMI-77.Conclusions: Mcl-1 inhibitor UMI-77 can induce the apoptosis of GBC-SD cells in a dose-dependent manner through the caspase-mediated endogenous apoptosis pathway. Therefore, Mcl-1 may become a new therapeutic target in the research on gallbladder cancer.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"12 8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72785819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of toll-like receptor 4 gene polymorphism and inflammatory factors in peripheral blood on patients with sepsis","authors":"Tieying Tian, Xi-yuan Xu","doi":"10.3760/CMA.J.ISSN.1673-436X.2019.02.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1673-436X.2019.02.006","url":null,"abstract":"Objective: To observe the presence of toll-like receptor 4 (TLR4) gene polymorphism in the venous blood in patients with sepsis, meanwhile, to observe the expression and the diagnostic value of TLR4 mRNA, interferon-γ (IFN-γ), interleukin-23 (IL-23), procalcitonin (PCT) and C-reactive protein (CRP) in patients with different degrees of sepsis.Methods: The peripheral blood samples from the subjects were collected to extract genomic DNA, gene sequencing and enzyme digestion method were applied to the detection of TLR4 Asp299Gly loci polymorphism. The expression of TLR4 mRNA in the peripheral blood was detected by reverse transcriptase polymerase chain reaction (RT-PCR). The expression levels of IFN-γ, IL-23, PCT and CRP were measured by enzyme linked immunosorbent assay (ELISA).Results: (1) The gene polymorphism was not present in TLR4 Asp299Gly loci; (2) The expression of TLR4 mRNA in the peripheral blood in patients with sepsis: on d1, there were statistically significant differences between the normal group and the group (APACHE II ≤ 20), between the normal group and the group (APACHE II > 20), between the group (APACHE II ≤ 20) and the group (AAPACHE II > 20) (t = 5.741, 14.780 and 10.500, all p < .01). APACHE II stands for Acute Physiology and Chronic Health Evaluation II. On d7, there were statistically significant differences between the normal group and the group (APACHE II ≤ 20), between the normal group and the group (APACHE II > 20), between the group (APACHE II ≤ 20) and the group (APACHE II > 20) (t = 4.186, 13.830 and 9.645, all p < .01); (3) The expression levels of IFN-γ, IL-23, PCT and CRP were obviously upregulated (all p < .01), and TLR4 was positively correlated with IFN-γ and IL-23 (all p < .01); (4) The best cutoff value of TLR4 mRNA at baseline was 891.6 μg/L, with a sensitivity of 100% and a diagnostic specificity of 57%. The best cutoff value of IFN-γ at baseline was 84.5 μg/L, with a sensitivity of 100% and a diagnostic specificity of 57%. The best cutoff value of IL-23 at baseline was 861 μg/L, with a sensitivity of 100% and a diagnostic specificity of 97%.Conclusions: (1) The Asp299Gly polymorphism is not present in TLR4 gene; (2) The expression levels of TLR4 mRNA, IFN-γ and IL-23 are relatively high in patients with sepsis, and will be higher with the increased severity of sepsis; (3) TLR4 mRNA, IFN-γ and IL-23 can be used as molecular biomarkers for the early diagnosis of sepsis.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89697882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis on clinical distribution and drug resistance of Klebsiella pneumoniae isolated for 5 consecutive years","authors":"Yue Li, Hong-bo Guo","doi":"10.14725/DCC.V5N4P36","DOIUrl":"https://doi.org/10.14725/DCC.V5N4P36","url":null,"abstract":"Objective: To analyze the clinical distribution and drug resistance of Klebsiella pneumoniae isolated from patients in a certain hospital and provide a basis for the rational use of antibiotics in the clinical treatment for the infection of Klebsiella pneumoniae . Methods: 1,192 strains of Klebsiella pneumoniae isolated from clinical specimens from 2012 to 2016 were collected. The strains were identified by VITEK-2 Compact Microbiological Identification System, and the corresponding results of the antimicrobial susceptibility test were interpreted in accordance with the standards recommended by Clinical and Laboratory Standards Institute (CLSI). Results: 1,192 strains of Klebsiella pneumoniae were mainly isolated from sputum (65.6%), and most of them were from Respiratory Medicine Department and Medical Intensive Care Unit of Respiratory Medicine Department (MICU), accounting for 41.4%. Out of 1,192 strains, 448 strains were detected to produce extended-spectrum beta-lactamases (ESBLs), accounting for 37.6%. In addition, the detection rates of ESBL-producing Klebsiella pneumoniae for 5 consecutive years showed an increasing trend year by year, and they were higher than the national average values published by China Antimicrobial Resistance Surveillance System (CARSS) in the corresponding period. The drug resistance rate of ESBL-producing Klebsiella pneumoniae was significantly higher than that of non ESBL-producing strains. Conclusions: The infection caused by Klebsiella pneumoniae mainly occurs in the lower respiratory tract, and the drug resistance rates of Klebsiella pneumoniae to antibiotics in the drug susceptibility spectrum are maintained at a high level. Therefore, the rational selection of antibiotics for the clinical treatment of lower respiratory tract infection caused by Klebsiella pneumoniae  must be based on the production of ESBLs and the results of antimicrobial susceptibility test.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78992638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibitory effect of survivin-shRNA on A431 cutaneous squamous cell carcinoma","authors":"Yu-qin Hao, Xia Liu, Shuxia Kang, Xin Zhang, Kun-Ming Zhang, Yongmeng Zhu","doi":"10.14725/DCC.V5N4P1","DOIUrl":"https://doi.org/10.14725/DCC.V5N4P1","url":null,"abstract":"Objective: To observe the effect of survivin-shRNA on A431 cutaneous squamous cell carcinoma (SCC) and explore the molecular biological mechanism of nuclear factor κB (NF-κB) in the inhibition of survivin-shRNA on cutaneous SCC. Methods: Survivin-shRNA adenovirus vector was constructed to screen out the best interference sequence. Nude mice were subcutaneously inoculated with the cultured A431 cell suspension to duplicate A431 transplanted tumor models. These mice were randomly divided into the blank control group, the rAd-EGFP negative control group, the rAd-survivin-shRNA transfection group and the Res positive control group, with 5 mice in each group. The corresponding reagents were injected into the tumors. All the mice were sacrificed on the 20 th day. The tumor tissues were isolated, with tumor volume and tumor weight measured, the tumor growth curves were accordingly plotted and the tumor inhibition rate was consequently calculated. Hematoxylin-eosin (HE) staining was used to observe the cellular morphology of the tumors. TUNEL was applied to the detection of cell apoptosis. Western blot was applied to the detection of the expression of Survivin, inhibitor of NF-κB (IκB), P65, P53 and Caspase-3. Results: As to the transplanted tumors, tumor volume and tumor weight were decreased in nude mice in the rAd-survivinshRNA transfection group and the Res positive control group, in comparison with the blank control group and the rAd-EGFP negative control group, the differences were of statistical significance ( p < .05); The results of TUNEL showed that the apoptosis rates were significantly increased in the rAd-survivin-shRNA transfection group and the Res positive control group, in comparison with the blank control group and the rAd-EGFP negative control group, the difference was statistically significant ( p < .05); In the rAd-survivin-shRNA transfection group and the Res positive control group, the microscopic observation showed a small amount of sparsely-distributed tumor cells, degenerative liquefactive necrosis, cancer cell shrinkage and round-shape, and karyopycnosis; The expressions of Survivin and P65 proteins were decreased in the rAd-survivin-shRNA transfection group and the Res positive control group, in comparison with the blank control group and the rAd-EGFP negative control group, the differences were statistically significant ( p < .05), while the expressions of IκB, P53 and Caspase-3 proteins were significantly increased, in comparison with the blank control group and the rAd-EGFP negative control group, the differences were statistically significant ( p < .05). Conclusions: Survivin-shRNA can inhibit the growth of the transplanted tumors in cutaneous SCC nude mice, one of the mechanisms is to promote the apoptosis of tumor cells and inhibit the growth of SCC transplanted tumors by inhibiting the NF-κB signaling pathway and then activating the tumor suppressor gene P53.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80818545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MAPK/ERK regulation of P53 in human epidermoid carcinoma cell line A431","authors":"Yu-qin Hao, Chun-sheng Kang, Xin Zhang, Shuxia Kang, Xia Liu","doi":"10.14725/DCC.V5N4P23","DOIUrl":"https://doi.org/10.14725/DCC.V5N4P23","url":null,"abstract":"Objective: To observe the impact of activation and inhibition of mitogen activated protein kinases (MAPK)/extracellular signalregulated protein kinase (ERK) signaling pathway on the proliferation and apoptosis of cutaneous squamous cell carcinoma (SCC). cells and investigate the interaction mechanism between MAPK/ERK signaling pathway and tumor suppressor gene P53 in SCC. Methods: Human A431 cells were cultured and divided into MAPK/ERK inhibition groups with low-, medium- and highconcentration of inhibitors (PD98059 + DMSO), MAPK/ERK activation groups with low-, medium- and high-concentration of stimuli (IGF + PBS) and blank control group (DMSO). The cell proliferation in vitro was detected by MTT assay, with the cell apoptosis detected by flow cytometry (FCM) and the protein expression of P-ERK and P53 detected by western blot in each group. Results: The A431 cell proliferation was inhibited by different concentrations of PD98059 with a clear concentration - effect and time - effect relationship ( p < .05); and the cell proliferation was promoted by the different concentrations of IGF with a clear concentration - effect and time - effect relationship ( p < .05). The FCM results showed a significant increase in the apoptosis rate of A431 cells which were treated with PD98059, with a clear concentration - effect relationship ( p < .05); while the apoptosis rate was decreased significantly after A431 cells were treated with IGF, also with a concentration - effect relationship ( p < .05). The western blot results showed that the expression of P-ERK protein was decreased but the expression of P53 was increased after A431 cells were treated with PD98059. With the concentration of PD98059 going up, the decrease in P-ERK and the increase in P53 were more significant ( p < .05); while the expression of P-ERK protein was increased but the expression of P53 was decreased after A431 cells were treated with IGF. With the concentration of IGF going up, the increase in P-ERK and the decrease in P53 were more significant ( p < .05). According to Pearson correlation analysis, the expression of P53 was negatively correlated to that of P-ERK ( p < .05). Conclusions: After MAPK/ERK signaling pathway was activated by IGF in A431 cells, the expression of pro-apoptotic factor P53 was decreased with the ability of cell proliferation enhanced and the ability of apoptosis reduced. However, after the inhibition of MAPK/ERK signaling pathway, the expression of pro-apoptotic factor P53 was increased with the ability of cell proliferation reduced and the ability of apoptosis increased.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"73 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86973160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vivo therapeutic effects of albendazole in combination with IFN-α on cystic echinococcosis in mice","authors":"Zhelin Yun, Yong-sheng Zhou, Yan Zhang, B. Li","doi":"10.14725/DCC.V5N4P9","DOIUrl":"https://doi.org/10.14725/DCC.V5N4P9","url":null,"abstract":"Objective: This study was aimed to evaluate the in vivo therapeutic effects of the combination of ABZ with interferon (IFN)-α on cystic echinococcosis (CE) in mice. Methods: After 5-month secondary infection with protoscolices, Balb/c mice were randomly divided into four groups: ABZtreated group, IFN-α-treated group, ABZ+IFN-α group and untreated control group. Drugs in different treated groups were respectively administered for 2 months. Blood was respectively taken from caudal veins in mice at treatment time points of 0 d, 7 d, 14 d, 28 d, 36 d, 48 d and 60 d, in order to detect the changes in the level of antibodies in the serum. Mice were then sacrificed after the end of treatment, and related indicators were detected to evaluate the therapeutic effects. Results: In comparison with untreated control group (p < .01) and ABZ-treated group (p < .05), ABZ+IFN-α group showed a more significant decrease in the number of cysts, cyst size and cyst weight. After transmission electron microscopy (TEM) of the cysts in different treated groups, it was found that, there was an obvious change in cyst ultrastructure in ABZ+IFN-α group. ELISA experimental results showed that, in ABZ+IFN-α group, there was a significant decrease in IL-10 in serums and splenocytes (p < .01); In comparison with untreated control group, ABZ+IFN-α group showed a more significant decrease in the levels of IgE, IgG and its subtypes (p < .01). Conclusions: In this study, the combination of ABZ with IFN-α was proved to be an effective CE treatment option.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78338132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of hyperbaric oxygen therapy on 32 cases of full-thickness skin grafting for the repair of defects on the hand and foot","authors":"Yanhua Zhou, Dong Wang","doi":"10.14725/DCC.V5N3P28","DOIUrl":"https://doi.org/10.14725/DCC.V5N3P28","url":null,"abstract":"Full-thickness skin grafting is one of the most commonly used repair methods for skin defects. It has the advantage of wear-resistant with less scar hyperplasia and less difficult to operate with no symptoms. Hyperbaric oxygen was used in this study after full-thickness skin grafting from September 2012 to August 2016 to achieve the best effect of skin survival after surgery.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87070740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}