临床病例讨论杂志(英文版)最新文献

{"title":"New progress in diagnostic techniques for hyperparathyroidism in nuclear medicine","authors":"Guowei Tan, Qinghe Yu, Hong Gu","doi":"10.5430/dcc.v10n1p28","DOIUrl":"https://doi.org/10.5430/dcc.v10n1p28","url":null,"abstract":"Hyperparathyroidism (HPT) is an endocrine system disease, which is often divided into primary hyperparathyroidism (PHPT) and secondary hyperparathyroidism (SHPT). At present, HPT has gradually become a common disease of endocrine system, and the common treatment is surgical resection of related lesions. Therefore, accurate location and detection are very important for the surgical treatment and prognosis of HPT. Therefore, the author reviews the relevant imaging examination in the field of nuclear medicine to provide help for clinical diagnosis and treatment.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":" 31","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135290660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The clinical characteristics of acute trauma and prognostic evaluation","authors":"Tong Zhou, Fan Li, Hanling He","doi":"10.5430/dcc.v9n3p23","DOIUrl":"https://doi.org/10.5430/dcc.v9n3p23","url":null,"abstract":"Acute trauma is one of the most commonly seen diseases in the Emergency Department, and it attracts more attention due to the increasing disability rate and mortality. Early rapid and accurate assessment of the severity of trauma has a positive significance for improving clinical prognosis. The paper aims to review the characteristics of the severity score based on trauma severity, blood biochemical changes and serum biomarkers, and discuss its prognostic significance.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":" 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135291441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of clinical audiological characteristics of noise-induced silent hearing loss","authors":"Chunmin Li, Xiaoxu Du, Dandan Zhang, Tuya Bai, Xiuli Xu","doi":"10.5430/dcc.v10n1p22","DOIUrl":"https://doi.org/10.5430/dcc.v10n1p22","url":null,"abstract":"Objective: To explore the characteristics of audiology examination of Noise-Induced Hidden Hearing Loss (NIHHL), and then explore its valuable diagnostic methods.Methods: A total of 80 young men aged between 19 and 35 were selected. They were classified into the experimental group with noise exposure history and the control group without noise exposure history, with 40 men in each group. We carried out extended high-frequency audiometry test for good ears; conducted speech in noise measurement and distortion product emission for good ears; DPOAE test, compare and analyze the results of each test.Results: The extended high frequency hearing threshold test results showed that the hearing threshold of the experimental group was larger than that of the control group at the frequency above 8kHz, with significant statistical difference (p < .01). The results of speech audiometry under noise showed that the signal-to-noise ratio loss in the experimental group was greater than that in the control group, with a significant statistical difference (p < .01). The results of otoacoustic emission showed that the signal-to-noise ratio of the experimental group was lower than that of the control group at the frequency of 6 kHz and above, with a statistically significant difference (p < .01). There is a correlation between pure tone audiometry and DPOAE test results at high frequencies (6 kHz: p <. 0001, r = -.478; 8 kHz: p < .0001, r = -.491;) ; There was a correlation between speech audiometry and DPOAE test results under noise (p = .031, r = -.299).Conclusion: Compared with the control group, the extended high frequency pure tone hearing threshold increased or could not be elicited in the experimental group, speech recognition ability decreased significantly under noise, DPOAE was normally elicited but signal-to-noise ratio decreased, and there was a certain correlation between them. The above three audiological examination methods have a certain reference value for early recognition of hidden hearing loss.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"20 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135684675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glutamine supplementation for rheumatic diseases: A systematic review","authors":"Jozélio Freire De Carvalho, Aaron Lerner","doi":"10.5430/dcc.v10n2p5","DOIUrl":"https://doi.org/10.5430/dcc.v10n2p5","url":null,"abstract":"na","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135617518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carotid to subclavian bypass, rare but rewarding surgery: A case report","authors":"R. Karmacharya, S. Vaidya, Binay Yadav, S. Sharma, S. Maharjan, S. Bhatt, Kajol Kunwar","doi":"10.5430/dcc.v10n2p1","DOIUrl":"https://doi.org/10.5430/dcc.v10n2p1","url":null,"abstract":"Different treatment options are available for subclavian stenosis (SS). Carotid to subclavian bypass surgery (CSBS) is an increasingly used effective treatment strategy when stenting is impossible. However, in Nepal, little is known about SS and its management. A 58-year-old man with a history of aortic valve replacement surgery complained of progressive left arm weakness for the past 6 months associated with pain on exertion and blood pressure discrepancies in both arms. A computed tomographic scan confirmed near-complete subclavian artery stenosis and a Doppler ultrasound showed decreased blood flow and systolic velocity. CSBS was selected as stenting was not feasible. Post-CSBS, all hemodynamic parameters returned to normal, lasting even after 2 years. CSBS appears to be a viable, safe, and promising treatment for symptomatic SS. However, additional studies need to be conducted to analyze the benefits of CSBS relative to other interventions.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84542417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on integrated treatment of severe burn in batch patients","authors":"S. Cao, T. Ba, Quan Li, Biao Zhou, Zengqiang Yan, Qiang Chen, Ling-feng Wang","doi":"10.5430/dcc.v9n3p18","DOIUrl":"https://doi.org/10.5430/dcc.v9n3p18","url":null,"abstract":"Objective: To explore the burn treatment and first aid flow mode in batch patients.Methods: A retrospective analysis was performed on the treatment experience of 10 or more patients in the group burn accident admitted to the Third Affiliated Hospital of Inner Mongolia Medical University from 2008 to 2020, in order to acquire the general information (e.g., age, sex [male and female], injury causes and factors, total burn surface area, inhalation injury and compound injury), the time when each first-aid rescue team was in place; the reception time of the triage group; specialist rescue start time; treatment process and treatment outcome in patients with severe burns, such as the establishment time of deep venous access.Results: 67 cases (n = 68) of patients were cured and the curative ratio was 98.5%. The average time from the rescue order of the commander-in-chief to the placement of each medical group was 8.8 minutes, the average reception time of the triage group was 4.5 minutes, the average specialist rescue start time was 18.6 minutes, and the average establishment time of deep vein access for patients with severe burns was about 11.3 minutes.Conclusions: Scientific and reasonable pre-hospital emergency triage and treatment for burn patients can be achieved by implementing integrated treatment.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"148 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78592618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression and significance of Shh, Gli1 and β-catenin in triple-negative breast cancer tissues","authors":"Zhiyu Wang, Huijie Zhang","doi":"10.5430/dcc.v9n4p16","DOIUrl":"https://doi.org/10.5430/dcc.v9n4p16","url":null,"abstract":"Objective: To detect the expression of Shh, Gli1 and β-catenin in triple negative breast cancer tissues and paracancer breast tissues by qRT-PCR and immunohistochemistry and to analyze their correlation with clinicopathological features.Methods: (1) qRT-PCR was used to detect the mRNA expression of Shh, Gli1 and β-catenin in 30 cases of triple negative breast cancer and their paracancer breast tissues, and the correlation among them was analyzed. (2) The expression of Shh, Gli1 and β-catenin proteins in 30 triple negative breast cancer and their paracancer breast tissues was detected by immunohistochemistry, and their correlation with clinicopathological features was analyzed.Results: (1) Shh mRNA expression (1.2334 ± 0.27867), Gli1 mRNA expression (1.2135 ± 0.20636) and β-catenin mRNA expression (1.1421 ± 0.32330) in triple negative breast cancer tissues were higher than that in paracancer breast tissues, i.e., Shh mRNA expression (1.0022 ± 0.06721), Gli1 mRNA expression (1.0003 ± 0.02420) and -catenin mRNA expression (1.0033 ± 0.07920) were significantly different (p < .05). There was a significantly positive correlation between the mRNA expression of Shh and Gli1 (r = .989, p < .001), and between the mRNA expression of Shh and β-catenin (r = .868, p < .001). There was a significantly positive correlation between the mRNA expression of Gli1 and β-catenin expression (r = .869, p < .001). (2) The positive expression rates of Shh, Gli1 and β-catenin in triple negative breast cancer tissues were 93.3% (28/30), 96.7% (29/30) and 93.3% (28/30), respectively, which were higher than those in paracancer tissues 60% (18/30), 73.3% (22/30) and 73.3% (22/30), the differences were statistically significant (p < .05). There was a significantly positive correlation between the mRNA expression of Shh and Gli1 (r = .958, p < .001), and between the mRNA expression of Shh and β-catenin (r = .952, p < .001). There was a significantly positive correlation between the mRNA expression of Gli1 and β-catenin expression (r = .927, p < .001). The expression of Shh, Gli1 and β-catenin protein in triple negative breast cancer was not correlated with age and tumor size (p > .05), but Shh was positively correlated with histological grade (G) (r = .774, p < .001). Furthermore, Gli1 was positively correlated with histological grade (r = .757, p < .001). β-catenin was positively correlated with histological grade (r = .739, p < .001). Shh was positively correlated with TNM staging (r = .460, p = .010). Gli1 was positively correlated with TNM staging (r = .414, p = .023). -catenin was positively correlated with TNM staging (r = .404, p = .027). Shh was positively correlated with lymph node metastasis (r = .540, p = .002). Gli1 was positively correlated with lymph node metastasis (r = .515, p = .004). β-catenin was positively correlated with lymph node metastasis (r = .559, p = .001).Conclusions: (1) The up-regulated expression of Shh, Gli1 and β-catenin proteins in triple negati","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83145527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review, impact, and future of severe and extra-severe burn treatment in China","authors":"Qiangqiang Shang, Ran An, Ling-feng Wang, Quan Li, S. Cao, Biao Zhou","doi":"10.5430/dcc.v10n1p10","DOIUrl":"https://doi.org/10.5430/dcc.v10n1p10","url":null,"abstract":"China began using the colored liquid from tea and tincture to treat burns as early as the sixth century B.C., and records of Chinese medicine for the rescue and treatment of burns date from the Jin Dynasty to the Ming and Qing Dynasties. Modern burn treatment medicine in China began in 1958 when national steel production began. Since then, burn patients have increased dramatically, independent burn departments have been established nationwide, and burn surgery has moved into technological development. With the combined efforts of several generations of burn medical workers in China, the clinical treatment of severe and extra-severe burns has steadily increased. Many fields, such as burn shock prevention and treatment, wound repair, and sepsis, have become world leaders in the 21st century, forming a treatment technology and theoretical system with distinctive Chinese characteristics. Burn medical professionals have conducted numerous clinical and fundamental experimental studies, founded the Burns Surgery Branch of the Chinese Medical Association, established academic journals, and successfully established China Burn Treatment Program. The advancement of science and technology has promoted the development of modern medicine, and 3D virtual reality technology, 3D printing technology, organoid culture, and tissue engineering skin have demonstrated potential advantages and excellent application prospects in the treatment of severe burns, providing new ideas and directions for the discipline’s development. In the new journey of development and reform, we should continue to strengthen the systematic construction of the discipline, enhance the innovative treatment capability, and create further triumph.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79809498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of fulminant myocarditis complicated by hemophagocytic syndrome","authors":"Xiao-wei Li, Yan-Qin Cui","doi":"10.5430/dcc.v10n1p5","DOIUrl":"https://doi.org/10.5430/dcc.v10n1p5","url":null,"abstract":"Background: Fulminant Myocarditis and Hemophagocytic Syndrome (HPS) are independent life-threatening diseases. HPS, however, is a rare complication of fulminant myocarditis. It is hard to diagnose HPS in patients with fulminant myocarditis early, but timely identification affects the clinical result. Here is the report of a female who has developed HPS complications after fulminant myocarditis.Case presentation: A 15-year-old Chinese female was admitted to the emergency department with a 3-day history of progressively severe chest pain and then a 1-day history of worsening heart failure needing the veno-arterial extracorporeal membrane oxygenation (V-A ECMO). Interventions: V-A ECMO requiring continuous renal replacement therapy (CRRT) supported critically ill patients with heart failure. The vasoactive drug was used to improve cardiac function, maintain water, electrolyte, and acid-base balance, and nutritional supplements. High-dose methylprednisolone was administered for three days. Etoposide was given two times according to the treatment guideline, followed by cyclosporine. Diagnosis: The definitive diagnosis of the presented case was fulminant myocarditis complicated by hemophagocytic lymphohistiocytosis.Conclusions: For fulminant myocarditis patients suspected of HPS, the functional examination must be considered for early diagnosis. The timely administration of adequate corticosteroids and standard chemotherapy is essential to reduce the risk of HPS mortality.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"50 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72486220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study on the depression status of pediatric standardized training residents in COVID-19","authors":"Yan Pan","doi":"10.5430/dcc.v10n1p1","DOIUrl":"https://doi.org/10.5430/dcc.v10n1p1","url":null,"abstract":"Objective: To analyze the depression status of pediatric standardized training residents in COVID-19.Methods: The depression status of pediatric residents undergoing standardized training at the First Affiliated Hospital of Yangtze University was investigated using the Self-rated Depression Scale (SDS). Statistical analysis was conducted using R version 3.5.3.Results: The prevalence of depression was found to be 66.6%. However, no significant statistical associations were observed between depression and various demographic factors, including gender, age, emotional status, educational background, possession of a professional doctor certificate, and monthly income.Conclusions: The incidence of depressive symptoms amongst pediatric residents undergoing standardized training during the COVID-19 pandemic is substantial, placing them at an elevated risk for depression.","PeriodicalId":63789,"journal":{"name":"临床病例讨论杂志(英文版)","volume":"155 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82849113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}