{"title":"An Unbiased Tissue Attenuation Coefficient Estimator Using Microbubble Echoes with Harmonic Ratio Compensation","authors":"Sheng-Kai Tsao, J. Tsao","doi":"10.1109/ICBEB.2012.64","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.64","url":null,"abstract":"For the tissue attenuation coefficient (TAC) estimator proposed in our previous paper [5], to have unbiased estimate of the TAC of separation tissue between two vessels, it needs bubbles in these two vessels have identical statistical properties, which can be achieved only when these two vessels have same diameter and blood pressure. To release this limitation, a compensation technique is proposed to suppress the bias. In this paper, follow Greenleaf's work, we introduce a parameter named harmonic ratio (HR), which is the ratio of two second-harmonic signals, for bias suppression. This method needs to use dual-frequency excitation to produce two harmonics. After applying HR to estimate TAC, it is shown that the effect of bubble number can be compensated. In the experimental work, we make two vessels with different bubble concentrations such that the statistical properties of bubble echoes are different to cause severe bias on TAC estimates, then it is shown that the estimates using HR can be kept unbiased.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"89 1","pages":"727-730"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77505544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing Cancer Risk of Coal-Fired Power Plant Workers Exposed to PAHs","authors":"Bin Li, Zhaolong Zhang, H. Fan, C. Zeng","doi":"10.1109/ICBEB.2012.82","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.82","url":null,"abstract":"To study the relationship between the concentration of urinary 1-OH-Py, 3-OH-BaP and the degree as well as the pathways of human exposure to PAHs, we collected 24-hour air, dietary and urine samples of 60 oven workers in a coal-fired power plant of Central China and 60 people in a general group not exposed to such PAHs in 2011. The concentrations of eight strong carcinogenic PAHs in air and dietary samples, and the concentrations of the urinary 1-OH-Py and 3-OH-BaP were determined. By studying the pathways of human exposure to PAHs, it is found that the main reason for coal-fired power plant workers' high cancer risk is the exposure to PAHs by breathing contaminated air, while the degree of exposure to PAHs through diet is similar to that of the general group. In order to reduce coal-fired power plant workers' cancer risk, occupational protection should be strengthened, and the working environment should be improved.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"59 1","pages":"1232-1235"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76770421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of Simulation on Attenuation of Diesel Oil during Remediation of Contaminated Soil by Enhancing Bioventing","authors":"Jin-Feng Yang, Zhao Tong-ke, Zhang Cheng-jun, Cheng Hong-han","doi":"10.1109/ICBEB.2012.373","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.373","url":null,"abstract":"Bioventing is an in situ forced oxidative soil remediation technology which combined soil vapor extraction with biodegradation. It has broad application prospects of soil contamination caused by underground storage tank leakage. In this paper, soil column experiment which was used to simulate diesel contamination was conducted. The law of balance distribution of residual TPH (Total Petroleum Hydrocarbon) concentration at different time and the changes of diesel amount in soil at different depths, together with total diesel amount of the entire column were analyzed. The results showed that: (1) The initial soil moisture content affects the distribution and changes of TPH content during the natural attenuation and enhancing bioventing. (2) Gravity diffusion and migration was the main causes for the changes of TPH content of entire column in the early days of natural attenuation, within one month. Approximately 2 months' venting later, extraction was prominent to maintain stable changes of the diesel concentration in the upper of soil column.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"2016 1","pages":"1718-1721"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73301654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chi Zhang, Shuyu Li, F. Pu, Xiaoyan Deng, Yubo Fan, Deyu Li, S. Xie
{"title":"Experimental Study on the Steady Flow in the Carotid Siphon: The Geometric Effect on the Hemodynamics","authors":"Chi Zhang, Shuyu Li, F. Pu, Xiaoyan Deng, Yubo Fan, Deyu Li, S. Xie","doi":"10.1109/ICBEB.2012.204","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.204","url":null,"abstract":"The siphon bend of internal carotid artery (ICA) has been reported as the most preferred location for stenoses. The geometry of the siphon is considered to be associated with the atherosclerotic stenos is. In the present study, the shape of ICA was classified into 3 types with different curvature and planarity. Accordingly, 3 siphon models were experimentally studied with particle image velocimetry technology. The velocity field of the experimental fluid in the models was measured to simulate the steady blood flow in the ICA siphon. The planarity was considered as an important geometric factor for stenoses, because the helical flow was found when the model has large non-planarity. The experimental measurement was validated with the computationally simulation. More geometric studies are necessary to elucidate the geometric effect on the hemodynamics and stenoses in the ICA siphon in the future.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"1 1","pages":"264-267"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88849147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacophore Model Generation of P2Y12 Inhibitor","authors":"Zhengqiang Yang, Yan-ling Zhang, Xing Wang, Yanjiang Qiao","doi":"10.1109/ICBEB.2012.293","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.293","url":null,"abstract":"A three dimensional pharmacophore model was generated for the molecules which are responsible for anti-platelet aggregation activities targeting platelet adp receptor (P2Y12). 24 structrurally diverse molecules were selected as training set to generate the hypothesis using Catalyst software 4.11. The best hypothesis comprises one hydrogen-bond acceptor, one aromatic ring, three hydrophobic points and one excluded volume and shows high correlation coefficient (0.999) as well as low RMS deviation (1.24). It has been further validated towards a test set and shows high correlation coefficient of test set (0.978). The values of effectively active hit A% and comprehensive evaluation index CAI are respectively 40% and 2.795. The results show that the pharmacophore we built is reliable and can be used to screen database. Furthermore, the best hypothesis was used to screen TCMD (Version 2005) database and the four hit compounds of higher predicted activity were the reported anti-platelet aggregation inhibitions, which may be useful for further study.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"100 1","pages":"396-399"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77197061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoyun Chen, Fuyu Sun, Wentao Sun, F. Yu, Zhiqiang Li
{"title":"Heavy Metals in Water, Soil and Aquatic Plants from a Rice-Crab Production Base of the Liao River Delta","authors":"Xiaoyun Chen, Fuyu Sun, Wentao Sun, F. Yu, Zhiqiang Li","doi":"10.1109/ICBEB.2012.237","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.237","url":null,"abstract":"In order to reveal the transformation of heavy metals in rice-crab ecosystems and to maintain the sustainable development of crab industry, it is important for evaluating the environmental quality of rice-crab production base of the Liao River Delta. Therefore, the contents of heavy metals in water, soil and aquatic plants of the rice-crab production base in the Liao River Delta were monitored from 2008 to 2010. The results showed that the contents of total Pb, Cd, Hg and As in the water and soil of the rice-crab production base were very low and qualified to the requirements for the green food crab. However, the contents of total Pb in some aquatic plants, such as Monochoria trifolia, Ceratophyllum demersum, Elodea Canadensis and Potamogeton distinct us, exceeded the limits of Pollution-free Food Standard for Freshwater Crab (NY 5072-2002). In conclusion, as the feed of crabs, these aquatic plants could affect the quality safety for raising rice-crab in the Liao River Delta, Northeast China.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"65 1","pages":"1503-1505"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91040678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fatty Acid Compositions in the Muscle of Schizothorax (Racoma) kozlovi from China","authors":"Ying-gui Dai","doi":"10.1109/ICBEB.2012.224","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.224","url":null,"abstract":"The fatty acid compositions in muscle of Schizothorax (Racoma) kozlovi were studied for the first time on the basis of fatty acid determination of 30 individuals of the species collected from the Wujiang River, China, by gas chromatography coupled with mass spectrometry. A total of 26 fatty acids were identified in the muscle of S. (R.) kozlovi. Palmitic acid (C16:0), stearic acid (C18:0), oleic acid (C18:1), palmitoleic acid (C16:1), linoleic acid (C18:2) and arachidonic acid (C20:4) were the most abundant fatty acids in the muscle. There were 6 fatty acids the amounts of which in the muscle showed significantly statistical difference between the immature and mature individuals of S. (R.) kozlovi. The amount of DHA in the muscle revealed significantly positive correlation with the age in the 30 individuals. It is possibly the sexual maturity rather than the ages, standard lengths or body weights of the individuals that have important effects on the amounts of fatty acids in the muscle of S. (R.) kozlovi. S. (R.) kozlovi may be a valuable food for humans due to its high amounts of C16:1, C18:1, C18:2 and C20:4 in the muscle.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"119 1","pages":"291-295"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73633311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Policy Implication for Emission Reduction of Dynamics between Energy Consumption and Economic Growth in China","authors":"Juan Yang","doi":"10.1109/ICBEB.2012.434","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.434","url":null,"abstract":"What is the relationship between China's energy consumption and economic growth? Will energy saving and emission cutting measures adversely affect economic growth? Based on the neoclassical production model, this study performs empirical analysis with the longest time series available in China. We combine the Directed A cyclic Graphs (DAG) with Cholesky decomposition to find the contemporaneous causal flows between energy and GDP, then employ the error correction model and impulse response to study the dynamics among these variables both in the long run and in the short run, finally we elaborate the important implication of dynamics between energy consumption and GDP growth for future emission reduction policy.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"111 1","pages":"1835-1840"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73412230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Regular Physical Activity on Patterns of Age-Related Changes in Photoplethysmogram Appearance Obtained at Fingertip","authors":"Lei Wang, Jingjing Zou, Xiaomin Luo","doi":"10.1109/ICBEB.2012.245","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.245","url":null,"abstract":"Objective To validate the association between age and photoplethysmogram appearance, explore the impact of regular physical activity to pulse shape pattern and quantify the effect on trend of relative changes with advancing age. Methods This experiment involved 231 Chinese participants (aged 21-60 years, mean 40.10 ± 11.61 years), and their photoplethysmography signals were recorded from left index finger in rest state. The categorical analysis of IPAQ was performed to classify the subjects into levels of regular physical activity. Results Significant correlation coefficients were observed positively for age and Aging Character Index, which supported the previously reported view of association between age and changes in pulse shape characteristics. Significant differences of Aging Character Index between levels of regular physical activity were observed and quantitatively analyzed in all age groups. Conclusion The impact of regular physical activity to aging effect can be quantitatively measured through biological marker derived from photoplethysmogram appearance for dose-response analysis.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"119 1","pages":"825-828"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73467178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhanced Production of Mycelia Biomass and Bioactive Metabolite of the American Ganoderma lucidum in Submerged Culture","authors":"M. Cui, Guoqing He","doi":"10.1109/ICBEB.2012.198","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.198","url":null,"abstract":"With the submerged fermentation kinetic characteristics of the American G. lucidum, we could determine that the optimal fermentation time was 6 days, and the biomass production reached 1.9138g/100ml, the production of ET, IT, EPS, IPS reached 18.3058mg/100ml, 49.8992mg/100ml, 15.4791 mg/100ml, 25.2431mg/100ml, respectively. The effect of fermentation condition (pH, rotation speed, inoculation, fungi age, vaccination days, incubation temperature) on the production of mycelia biomass, IPS, IT was also detailed studied. With the comparison of production of mycelia biomass, IPS, IT, the optimal fermentation condition was determined.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":"57 1","pages":"252-255"},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73704709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}