2012 International Conference on Biomedical Engineering and Biotechnology最新文献

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An Unbiased Tissue Attenuation Coefficient Estimator Using Microbubble Echoes with Harmonic Ratio Compensation 带谐波比补偿的微泡回波无偏组织衰减系数估计
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.64
Sheng-Kai Tsao, J. Tsao
{"title":"An Unbiased Tissue Attenuation Coefficient Estimator Using Microbubble Echoes with Harmonic Ratio Compensation","authors":"Sheng-Kai Tsao, J. Tsao","doi":"10.1109/ICBEB.2012.64","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.64","url":null,"abstract":"For the tissue attenuation coefficient (TAC) estimator proposed in our previous paper [5], to have unbiased estimate of the TAC of separation tissue between two vessels, it needs bubbles in these two vessels have identical statistical properties, which can be achieved only when these two vessels have same diameter and blood pressure. To release this limitation, a compensation technique is proposed to suppress the bias. In this paper, follow Greenleaf's work, we introduce a parameter named harmonic ratio (HR), which is the ratio of two second-harmonic signals, for bias suppression. This method needs to use dual-frequency excitation to produce two harmonics. After applying HR to estimate TAC, it is shown that the effect of bubble number can be compensated. In the experimental work, we make two vessels with different bubble concentrations such that the statistical properties of bubble echoes are different to cause severe bias on TAC estimates, then it is shown that the estimates using HR can be kept unbiased.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77505544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Assessing Cancer Risk of Coal-Fired Power Plant Workers Exposed to PAHs 评估燃煤电厂工人接触多环芳烃的癌症风险
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.82
Bin Li, Zhaolong Zhang, H. Fan, C. Zeng
{"title":"Assessing Cancer Risk of Coal-Fired Power Plant Workers Exposed to PAHs","authors":"Bin Li, Zhaolong Zhang, H. Fan, C. Zeng","doi":"10.1109/ICBEB.2012.82","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.82","url":null,"abstract":"To study the relationship between the concentration of urinary 1-OH-Py, 3-OH-BaP and the degree as well as the pathways of human exposure to PAHs, we collected 24-hour air, dietary and urine samples of 60 oven workers in a coal-fired power plant of Central China and 60 people in a general group not exposed to such PAHs in 2011. The concentrations of eight strong carcinogenic PAHs in air and dietary samples, and the concentrations of the urinary 1-OH-Py and 3-OH-BaP were determined. By studying the pathways of human exposure to PAHs, it is found that the main reason for coal-fired power plant workers' high cancer risk is the exposure to PAHs by breathing contaminated air, while the degree of exposure to PAHs through diet is similar to that of the general group. In order to reduce coal-fired power plant workers' cancer risk, occupational protection should be strengthened, and the working environment should be improved.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76770421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of Simulation on Attenuation of Diesel Oil during Remediation of Contaminated Soil by Enhancing Bioventing 加强生物通风修复污染土壤过程中柴油衰减模拟研究
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.373
Jin-Feng Yang, Zhao Tong-ke, Zhang Cheng-jun, Cheng Hong-han
{"title":"Study of Simulation on Attenuation of Diesel Oil during Remediation of Contaminated Soil by Enhancing Bioventing","authors":"Jin-Feng Yang, Zhao Tong-ke, Zhang Cheng-jun, Cheng Hong-han","doi":"10.1109/ICBEB.2012.373","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.373","url":null,"abstract":"Bioventing is an in situ forced oxidative soil remediation technology which combined soil vapor extraction with biodegradation. It has broad application prospects of soil contamination caused by underground storage tank leakage. In this paper, soil column experiment which was used to simulate diesel contamination was conducted. The law of balance distribution of residual TPH (Total Petroleum Hydrocarbon) concentration at different time and the changes of diesel amount in soil at different depths, together with total diesel amount of the entire column were analyzed. The results showed that: (1) The initial soil moisture content affects the distribution and changes of TPH content during the natural attenuation and enhancing bioventing. (2) Gravity diffusion and migration was the main causes for the changes of TPH content of entire column in the early days of natural attenuation, within one month. Approximately 2 months' venting later, extraction was prominent to maintain stable changes of the diesel concentration in the upper of soil column.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73301654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental Study on the Steady Flow in the Carotid Siphon: The Geometric Effect on the Hemodynamics 颈动脉虹吸稳定血流的实验研究:几何效应对血流动力学的影响
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.204
Chi Zhang, Shuyu Li, F. Pu, Xiaoyan Deng, Yubo Fan, Deyu Li, S. Xie
{"title":"Experimental Study on the Steady Flow in the Carotid Siphon: The Geometric Effect on the Hemodynamics","authors":"Chi Zhang, Shuyu Li, F. Pu, Xiaoyan Deng, Yubo Fan, Deyu Li, S. Xie","doi":"10.1109/ICBEB.2012.204","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.204","url":null,"abstract":"The siphon bend of internal carotid artery (ICA) has been reported as the most preferred location for stenoses. The geometry of the siphon is considered to be associated with the atherosclerotic stenos is. In the present study, the shape of ICA was classified into 3 types with different curvature and planarity. Accordingly, 3 siphon models were experimentally studied with particle image velocimetry technology. The velocity field of the experimental fluid in the models was measured to simulate the steady blood flow in the ICA siphon. The planarity was considered as an important geometric factor for stenoses, because the helical flow was found when the model has large non-planarity. The experimental measurement was validated with the computationally simulation. More geometric studies are necessary to elucidate the geometric effect on the hemodynamics and stenoses in the ICA siphon in the future.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88849147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacophore Model Generation of P2Y12 Inhibitor P2Y12抑制剂药效团模型的生成
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.293
Zhengqiang Yang, Yan-ling Zhang, Xing Wang, Yanjiang Qiao
{"title":"Pharmacophore Model Generation of P2Y12 Inhibitor","authors":"Zhengqiang Yang, Yan-ling Zhang, Xing Wang, Yanjiang Qiao","doi":"10.1109/ICBEB.2012.293","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.293","url":null,"abstract":"A three dimensional pharmacophore model was generated for the molecules which are responsible for anti-platelet aggregation activities targeting platelet adp receptor (P2Y12). 24 structrurally diverse molecules were selected as training set to generate the hypothesis using Catalyst software 4.11. The best hypothesis comprises one hydrogen-bond acceptor, one aromatic ring, three hydrophobic points and one excluded volume and shows high correlation coefficient (0.999) as well as low RMS deviation (1.24). It has been further validated towards a test set and shows high correlation coefficient of test set (0.978). The values of effectively active hit A% and comprehensive evaluation index CAI are respectively 40% and 2.795. The results show that the pharmacophore we built is reliable and can be used to screen database. Furthermore, the best hypothesis was used to screen TCMD (Version 2005) database and the four hit compounds of higher predicted activity were the reported anti-platelet aggregation inhibitions, which may be useful for further study.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77197061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Heavy Metals in Water, Soil and Aquatic Plants from a Rice-Crab Production Base of the Liao River Delta 辽河三角洲稻蟹生产基地水体、土壤及水生植物重金属含量分析
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.237
Xiaoyun Chen, Fuyu Sun, Wentao Sun, F. Yu, Zhiqiang Li
{"title":"Heavy Metals in Water, Soil and Aquatic Plants from a Rice-Crab Production Base of the Liao River Delta","authors":"Xiaoyun Chen, Fuyu Sun, Wentao Sun, F. Yu, Zhiqiang Li","doi":"10.1109/ICBEB.2012.237","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.237","url":null,"abstract":"In order to reveal the transformation of heavy metals in rice-crab ecosystems and to maintain the sustainable development of crab industry, it is important for evaluating the environmental quality of rice-crab production base of the Liao River Delta. Therefore, the contents of heavy metals in water, soil and aquatic plants of the rice-crab production base in the Liao River Delta were monitored from 2008 to 2010. The results showed that the contents of total Pb, Cd, Hg and As in the water and soil of the rice-crab production base were very low and qualified to the requirements for the green food crab. However, the contents of total Pb in some aquatic plants, such as Monochoria trifolia, Ceratophyllum demersum, Elodea Canadensis and Potamogeton distinct us, exceeded the limits of Pollution-free Food Standard for Freshwater Crab (NY 5072-2002). In conclusion, as the feed of crabs, these aquatic plants could affect the quality safety for raising rice-crab in the Liao River Delta, Northeast China.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91040678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Impact of Regular Physical Activity on Patterns of Age-Related Changes in Photoplethysmogram Appearance Obtained at Fingertip 有规律的体育活动对指尖光体积描记图外观年龄相关变化模式的影响
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.245
Lei Wang, Jingjing Zou, Xiaomin Luo
{"title":"Impact of Regular Physical Activity on Patterns of Age-Related Changes in Photoplethysmogram Appearance Obtained at Fingertip","authors":"Lei Wang, Jingjing Zou, Xiaomin Luo","doi":"10.1109/ICBEB.2012.245","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.245","url":null,"abstract":"Objective To validate the association between age and photoplethysmogram appearance, explore the impact of regular physical activity to pulse shape pattern and quantify the effect on trend of relative changes with advancing age. Methods This experiment involved 231 Chinese participants (aged 21-60 years, mean 40.10 ± 11.61 years), and their photoplethysmography signals were recorded from left index finger in rest state. The categorical analysis of IPAQ was performed to classify the subjects into levels of regular physical activity. Results Significant correlation coefficients were observed positively for age and Aging Character Index, which supported the previously reported view of association between age and changes in pulse shape characteristics. Significant differences of Aging Character Index between levels of regular physical activity were observed and quantitatively analyzed in all age groups. Conclusion The impact of regular physical activity to aging effect can be quantitatively measured through biological marker derived from photoplethysmogram appearance for dose-response analysis.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73467178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Expression of Alpha-smooth Muscle Action in Goat Temporomandibular Joint Disc and Its Effect on Self-Assembled Engineered Constructs 山羊颞下颌关节盘α -平滑肌活动的表达及其对自组装工程结构的影响
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.211
Hong Kang, Mengyi Qi, G. Bao
{"title":"Expression of Alpha-smooth Muscle Action in Goat Temporomandibular Joint Disc and Its Effect on Self-Assembled Engineered Constructs","authors":"Hong Kang, Mengyi Qi, G. Bao","doi":"10.1109/ICBEB.2012.211","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.211","url":null,"abstract":"Purpose of this study was to investigate the expression of smooth muscle action-alpha (α-SMA) in native goat temporomandibular joint (TMJ) disc and in self-assembled construct of TMJ disc. Expression of a-SMA in native one-month-aged goat TMJ disc was examined by immunohistochemistry (IHC) method. TMJ disc cells were isolated from one-month-aged goat TMJ discs with 0.1% type I collagenase and passaged to P3 for tissue engineering. 5.5×10(6) cells were seeded into 5 mm diameter wells filled with 2% agarose gels in which 10μg/L IGF-I growth factor was added to stimulate mature process of self-assembled constructs of TMJ disc. Dimensions, forms and weights of constructs were measured respectively at the second, fourth, sixth and eighth week. IHC staining was used to examine the distribution of α-SMA in self-assembled constructs. The IHC staining for α-SMA was globally uniformly distributed in all four groups of self-assembled constructs and expressed the strongest in the second group. This experiment also confirmed that much more significant expression of α-SMA in self-assembled constructs than in the native TMJ disc tissue. Conclusively, α-SMA could take part in the regulating developmental process of engineered construct and may be used partially to explain the reason why TMJ disc self-assembled constructs become much smaller and denser during its growth and development due to its volume shrinkage.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89074861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Function and Localization Analysis of Zebrafish Rspo1 斑马鱼Rspo1基因的功能及定位分析
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.231
Dongchang Sun, Yanmei Zhang
{"title":"Function and Localization Analysis of Zebrafish Rspo1","authors":"Dongchang Sun, Yanmei Zhang","doi":"10.1109/ICBEB.2012.231","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.231","url":null,"abstract":"R-spondin family factors, known as regulators of β-catenin signaling pathway, are conserved in vertebrate. They play roles in multiple processes during vertebrate development. Rspo1, a member of R-spondin family, regulates sex differentiation in both mammals (e.g. mouse) and reptiles (e.g. turtle). However, the role of Rspo1 in fish remains elusive. Our previous work showed the expression of Rspo1 in zebrafish (zRspo1). In this study, we further investigated potential function of zRspo1. We compared Rspo1 homologs in zebrafish and in human (hRspo1-4). By bioinformatics analysis, we predicted that zRspo1 functions on activating β-catenin signaling through a manner similar to hRSpo1. By histag indication, we detected zRspo1 on cell membrane and Golgi apparatus in zebrafish liver cells. This result suggests that zRspo1 may first secrete to the milieu and then extracellular zRspo1 activates β-catenin.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89082559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preparation of a P-rich Soil Amendment and Its Effect on the Pot Growth of White Mustard 富磷土壤改良剂的制备及其对白芥菜盆栽生长的影响
2012 International Conference on Biomedical Engineering and Biotechnology Pub Date : 2012-05-28 DOI: 10.1109/ICBEB.2012.305
Yongli Li, Lin Shi
{"title":"Preparation of a P-rich Soil Amendment and Its Effect on the Pot Growth of White Mustard","authors":"Yongli Li, Lin Shi","doi":"10.1109/ICBEB.2012.305","DOIUrl":"https://doi.org/10.1109/ICBEB.2012.305","url":null,"abstract":"A pot growing test was conducted to evaluate the amelioration effect of the P-rich soil amendment on acid soil and pot growth effect of the white mustard. The P-rich soil amendment was prepared by calcinating a mixture of low-grade rock phosphate and dolomite with a fusing agent of CaSO4. The amendment was rich in P, Si, Ca, Mg and S nutrient elements and displayed an alkalescent. The contents of nutrient elements in the soil amendment dissolved in 0.1 mol·L-1 citric acid solution were 8.94% P2O5, 19.82% CaO, 3.97% MgO, 13.37% SiO2 and 0.86% SO42-. Its pH value was 9.16. In the pot growing, the soil amendment was applied to the pot at four application rates, 1 g/Kg(L1), 2 g/Kg(L2), 3 g/Kg(L3), 4 g/Kg(L4) with 7 treatments and control (CK). The results of white mustard growth for 2 months indicated that applying the P-rich soil amendment could effectively increase the seeding emergence, the whole plant height, the stem thickness, the root length, the dry and wet biomass. The optimized application rate of the P-rich soil amendment was 3g·kg-1. The growth rate of biomass (wet weight) reached 13.52%~115.80%. The experimental results also suggested that the P-rich soil amendment could increase the biomass of white mustard and ameliorate the acid soil, and improve the content of the available phosphorus in the soil.","PeriodicalId":6374,"journal":{"name":"2012 International Conference on Biomedical Engineering and Biotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81413856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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