Journal of Environmental Health Science and Engineering最新文献

{"title":"Advancing microplastic pollution management in aquatic environments through artificial intelligence","authors":"Mudita Nagpal,&nbsp;Krrishika Gupta,&nbsp;Tanisha Gupta,&nbsp;Ankit Mittal,&nbsp;Nidhi Sharma","doi":"10.1007/s40201-025-00958-w","DOIUrl":"10.1007/s40201-025-00958-w","url":null,"abstract":"<div><p>The rising infiltration of microplastics (MPs) into aquatic environments is a complex and alarming threat jeopardizing marine biodiversity, destabilizing entire ecosystems, and endangering human health. Traditional methods for identifying and characterizing microplastics are often manual, requiring significant time and effort due to the small size, diverse shapes, and varying sources of microplastics. By integrating artificial intelligence (AI) with traditional environmental approaches, we can make significant progress in mitigating the influence of microplastics on aquatic ecosystems and health of humans. This review emphasizes the goals, benefits, results, and key insights of emerging robotics and various AI models across three critical areas: collection and sorting of microplastic waste, characterization of microplastic waste to determine its abundance, size and chemical composition and predicting and monitoring microplastic degradation. Several countries and organizations are using AI technologies to address microplastic pollution through innovative projects and supportive policies. The review aims to highlight these successful initiatives focused on monitoring, prevention, and cleanup of microplastics in aquatic environments. Further, challenges and future research opportunities on integrating robotics and AI technologies in mitigating microplastic pollution have also been discussed.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145110509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical Composition and Oxidative Potential of PM2.5 in Ambient Air of Tehran","authors":"Nahid Khoshnamvand,&nbsp;Kazem Naddafi,&nbsp;Mohammad Sadegh Hassanvand,&nbsp;Bahram Kamarei,&nbsp;Naga Raju Maddela","doi":"10.1007/s40201-025-00960-2","DOIUrl":"10.1007/s40201-025-00960-2","url":null,"abstract":"<div><p>The carcinogenicity of air pollution has been well established and is considered a threat to humans worldwide. Researchers have concluded although the properties of particulate matter (PM) such as size, shape, and mass are of primary importance for the study of air quality, another parameter such as oxidation potential (OP) can be used to determine particle toxicity or the health consequences related to PM samples. Here, the present study examines the characteristics of PM_2.5 components and their associated oxidation potential in the ambient air of Tehran, Iran using the dithiothreitol (DTT) assay. This study also compares the values of OP, and chemical composition (e.g.; anions and cations, metalloids, and polycyclic aromatic hydrocarbons (PAHs)) in the ambient air of Tehran with other urban areas globally. Sampling was conducted for nine months during three seasons: spring, summer, and autumn, in the ambient air of Tehran city, the capital of Iran from 2021/4/17 to 2021/12/6. According to the US EPA’s Sampling Schedule, a high-volume air sampler (operating at a flow rate of 1.415 m³/min) was employed for PM_2.5 on fiberglass filters once every six days. The average value of DTTv was equal to 0.8 ± 0.3 (nmol.min⁻¹m⁻³). The average values of DTTm were equal to 0.017 ± 0.01 (nmol.min⁻¹ µg⁻¹). Although the values of DTTv and DTTm in Tehran were relatively tolerable compared to other parts of Asia, they were at a high level compared to European and American countries. Nonetheless, DTTv in autumn was significantly higher than in summer and spring, while DTTm was slightly higher in spring than summer.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145100830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesis of Alginate-nZVIs biosorbent spheres for removal of Rhodamine B and Methylene Blue in aqueous media","authors":"Trung-Dung Dang,&nbsp;Quynh Xuan Thi Nguyen,&nbsp;D. Nguyen,&nbsp;Woo Jin Chung,&nbsp;S. Woong Chang,&nbsp;D. Duc Nguyen,&nbsp;Duong Duc La","doi":"10.1007/s40201-025-00953-1","DOIUrl":"10.1007/s40201-025-00953-1","url":null,"abstract":"<div><p>Environmental pollution is increasingly negatively affecting our lives, requiring advanced methods and materials that are highly effective for pollutant treatment processes. This study proposes the synthesis of zero-valent iron nanoparticles (nZVIs) through a green chemistry approach, which were then encapsulated in calcium alginate (Alg) spheres for application in the treatment of Rhodamine B (RhB) and Methylene Blue (MB). The morphology and structure of the alginate particles encapsulating zero-valent iron nanoparticles (Alg-nZVIs) were characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). The analytical results indicate that the material consists of alginate polymer particles with an average diameter of 2.5 mm, containing nZVIs with an average size of 50 nm. Factors affecting the treatment of RhB and MB, including the proportion of components in the material, pH, solution concentration, and treatment time, were studied and evaluated by UV–Vis method. This material showed high removal efficiency for RhB and MB. 0.08 ml nZVIs in 1 g of Alg-nZVIs beads treated 100 mL of RhB 5 mg/L at pH 7 for 180 min with an efficiency of over 90%. The same amount of material effectively treated 100 mL of MB 5 g/L at pH 3 for 120 min with an efficiency of over 90%. The prepared Alg-nZVIs spheres were easy to collect and reuse for up to 6 cycles with a decrease in removal efficiency of less than 15%. Alginate-nZVIs spheres are derived from readily available and natural materials through a clean, cost-effective, and economically sustainable technique.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution patterns, sources and risk assessment of atrazine in the Naseri wetland, as the biggest artificial water body in South of Iran","authors":"Rahim Jafari,&nbsp;Farnaz Almasi,&nbsp;Elham Maraghi,&nbsp;Bamshad Shenavar,&nbsp;Nematollah Jaafarzadeh,&nbsp;Afshin Takdastan,&nbsp;Aliakbar Babaei,&nbsp;Sahand Jorfi","doi":"10.1007/s40201-025-00955-z","DOIUrl":"10.1007/s40201-025-00955-z","url":null,"abstract":"<div><h3>Purpose</h3><p>The Naseri Artificial Wetland was created by the discharge of agricultural drainage water, including effluent from the sugarcane development project. The continuous inflow of drainage water from the sugarcane development units has altered the natural regime of the wetland. Considering the high probability of herbicides entering agricultural runoff, this study was conducted to identify atrazine and to assess the health risks of it in this wetland.</p><h3>Methods</h3><p>Sixty water samples from the wetland and 15 samples from the drainage channel were collected in three seasons: June (summer), October (Autumn), and February(winter). Variables such as electrical conductivity, dissolved oxygen, temperature, and pH were also monitored at the sampling points.</p><h3>Results</h3><p>The average measured ATZ concentration in NAW was lowest in June (0.015 mg/L) and was 0.021 mg/L in October and 0.024 mg/L in February. The average ATZ concentration in the drainage channel in June, October, and February was 0.03, 0.04, and 0.05 mg/L, respectively. The average electrical conductivity and pH in June and October were 29,900 µS/cm, 28,544 µS/cm and 7.29 and 7.28, respectively. The maximum and minimum values ​​of temperature were 30.7 °C in June and 8.6 in February.</p><h3>Conclusion</h3><p>The health risk for children and adults, based on the HQ index, was calculated to be 0.12 and 0.014, respectively. Additionally, the carcinogenic risk, based on the ILCR index, was calculated to be 2.7E-2 and 3.2E-3, respectively, which indicates the risk of carcinogenic.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144909763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling airborne transmission of viral genome using computational fluid dynamics simulation: A case study for SARS-CoV-2 virus","authors":"Somayeh Soleimani-Alyar,&nbsp;Igor Burstyn,&nbsp;Rasoul Yarahmadi,&nbsp;Alireza Alipoor","doi":"10.1007/s40201-025-00950-4","DOIUrl":"10.1007/s40201-025-00950-4","url":null,"abstract":"<div><p>Predicting indoor air quality during infectious disease conditions relies on models simulating particle materials (PM)/bioaerosols distribution. Understanding the thermo-fluid properties of exhaled air is crucial for comprehending disease transmission dynamics. This study employs a computational fluid dynamics (CFD) model to simulate cough-induced particle dispersion in a closed space. Furthermore, the number of released particles and the presence of SARS-CoV-2 viral genomes by a cough were assessed (in eight COVID-19 patients). According to the CFD model, in the first 30 s of cough, the vertical height and lateral breadth of the particles’ dispersion were up to 138cm and 92cm, respectively. As the distance from the patient's respiratory zone increased, the lateral distribution width of particles expanded, reaching 1.3 m at 2.4 m away. Larger droplets (&gt; 62.5µ) were deposited at shorter distances, while smaller particles remained airborne longer. The comparison of experimental and simulated results focused on particle dispersion at specific distances from the patient, particularly in the 2.5µ range. The distribution pattern of PM_2.5 and PM₁₀ at a distance of 1 and 2 m for women, not men, is similar to the distribution pattern of PM in CFD modeling. Viral genome detection was more prevalent in particles near the left side of the body, especially within the first 20 min post-cough, exhibiting a correlation with CFD predictions.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced short-term prediction of urban PM2.5 concentrations by improved hybrid deep learning","authors":"Yin Zhou,&nbsp;Yaping Lyu,&nbsp;Xiuli Dang,&nbsp;Roland Bol,&nbsp;Peng Zhang,&nbsp;Na Yu,&nbsp;Yuling Zhang","doi":"10.1007/s40201-025-00954-0","DOIUrl":"10.1007/s40201-025-00954-0","url":null,"abstract":"<div><h3>Purpose</h3><p>The aim of this study was to investigate the impact of improved deep learning model on the predictive performance of PM_2.5 concentration.</p><h3>Methods</h3><p>We developed a new model combining one-dimensional convolutional neural network and bidirectional long short-term memory neural network to predict PM_2.5 concentrations at hourly intervals. The air pollution observation data from 2020 to 2022 collected at several national air quality monitoring stations in Shenyang (Liaoning province, China) were employed to train our model. The performance of the proposed model was boosted by connecting the layer of network calculated results with the PM_2.5 sequence data. Furthermore, data of most relevant air quality monitoring stations and PM_2.5 feature factors of the target station were screened. The spatial correlation of major air pollutant and the interaction between PM_2.5 and other pollutant factors were therefore considered to improve the accuracy of the model.</p><h3>Results</h3><p>The root mean square error, mean absolute error, mean absolute percentage error of the new method were reduced by 49%, 51%, 44% and the R² was improved by 4.6% respectively compared with the control group for the next hour prediction. The proposed improvement method can reduce the prediction error of the model in the next 6 h.</p><h3>Conclusions</h3><p>In this study, the proposed model improvement method can significantly reduce the error of the model in predicting PM_2.5 concentration. The proposed method can improve the model in the next 6 h prediction accuracy. This study provides a new perspective for establishing high-precision models for PM_2.5 prediction.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144894072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green synthesized Fe nanoparticle assisted biomass hydrolysis for bioenergy production: process parameters optimization through combined RSM and ANN based approach","authors":"Rai Vibha,&nbsp;P. Ujwal,&nbsp;K. Sandesh","doi":"10.1007/s40201-025-00952-2","DOIUrl":"10.1007/s40201-025-00952-2","url":null,"abstract":"<div><p>Bioenergy plays a crucial role in addressing the global energy crisis. The utilization of agricultural byproducts for biofuel production through fermentation is well-established. Among various pretreatment methods, breaking lignin and cellulose bonds under heat and pressure to release sugar moieties is the most predominant approach. This study focuses on enhancing sugar yield through the most economical, energy-efficient, and time-saving pretreatment of the highly underrated agricultural residue, cocoa pod shell (CPS), using green-synthesized FeO nanoparticles derived from CPS extract. The synthesized nanoparticles, ranging from 25 nm to 31 nm in size, exhibited an EDS spectrum confirming the atomic composition of C (30.01%), Fe (6.09%), O (59.76%), N (2.36%), P (0.79%), Cl (0.53%), and K (0.46%). FTIR analysis revealed the presence of O-H, C-H, C-Cl, and O = C = O stretching, indicating effective nanoparticle capping. The novel ex-situ hydrolysis process, coupled with induction heating, yielded 356.04 g/L of total sugars and 60.28 g/L of reducing sugars using 10% w/v biomass and 4% acid within just 30 min. RSM and ANN modeling were employed for process validation, yielding R² values of 0.91 and 0.92 for total and reducing sugars, respectively, while ANN modeling achieved R² values of 0.96 and 0.97. This energy-efficient hydrolysis process achieved a significant sugar yield in less time while requiring minimal raw material. It presents a scalable and reliable approach to the industries, providing a promising direction for biofuel production.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of prenatal exposure to phthalates with risks of asthma, wheeze, and allergic diseases during childhood: a systematic review and meta-analysis","authors":"Jingxuan Yang,&nbsp;Mingjie Zhang,&nbsp;Jie Luo,&nbsp;Jiajun Pan,&nbsp;Tao Luo,&nbsp;Wenxing Yang","doi":"10.1007/s40201-025-00951-3","DOIUrl":"10.1007/s40201-025-00951-3","url":null,"abstract":"<div>\u0000 \u0000 <span>AbstractSection</span>\u0000 Background\u0000 <p>Phthalates are one of the most common environmental contaminants and endocrine disruptors. Environmental exposure to phthalates may increase the risk for allergic diseases. However, the existing literature presents conflicting findings regarding the long-term impact of early-life exposure to these substances.</p>\u0000 \u0000 <span>AbstractSection</span>\u0000 Methods\u0000 <p>We searched the Web of Science, PubMed and Google Scholar, Medline and Embase databases for all related publications from 1974 to September 1st, 2024. Ultimately, 22 studies with a total of 16,161 participants were selected. The relative risks (RRs) with 95% confidence intervals (95% CIs) were used to evaluate whether prenatal phthalate exposure is associated with allergic endpoints. To assess statistical heterogeneity across studies, both the Q-test and <i>I</i>^<i>2</i> statistic were adopted. Publication bias of the included studies was evaluated using Begg’s and Egger’s tests. Stratified analysis was conducted based on the gender of children, molecular weight of phthalates, disease type, phthalate species, parental exposure period and region. The systematic literature search protocol was formally registered in PROSPERO.</p>\u0000 \u0000 <span>AbstractSection</span>\u0000 Results\u0000 <p>Childhood wheeze (RR 1.10, 95% CI: 1.00-1.21), eczema (RR 1.09, 95% CI: 1.01–1.17), and rhinitis (RR 1.05, 95% CI: 1.02–1.09) are potentially associated with prenatal exposure to phthalates, particularly butyl-benzyl phthalate (RR 1.15, 95% CI: 1.06–1.24), di-ethyl-hexyl phthalate (RR 1.08, 95% CI: 1.02–1.15) and di-iso-nonyl phthalate (RR 1.12, 95% CI: 1.02–1.23).</p>\u0000 \u0000 <span>AbstractSection</span>\u0000 Conclusion\u0000 <p>Maternal phthalate exposure during pregnancy exhibits a significant association with elevated risks of childhood respiratory and allergic manifestations, including wheezing episodes, eczematous dermatitis, and rhinitis symptoms.</p>\u0000 \u0000 </div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new perspective on climate change in the geography of Iran: current and potential future implications","authors":"Hassan Nasirian,&nbsp;Kazem Naddafi","doi":"10.1007/s40201-025-00948-y","DOIUrl":"10.1007/s40201-025-00948-y","url":null,"abstract":"<div><p>Climate change is a global issue that presents significant challenges for countries worldwide, including Iran. Researchers need up-to-date information on climate change within their own country, including statistics on its severity, efforts to address it, and the impacts on the environment, temperatures, extreme weather events, water resources, agriculture, biodiversity, migration, air quality, and human health. This review provides an overview of these topics in the context of Iran, discussing challenges, sustainable practices, renewable energy, government responses, and international collaborations to mitigate climate change effects. It aims to offer a comprehensive perspective on the current and potential future implications of climate change in Iran. Climate change in Iran has resulted in higher temperatures, droughts, and wildfires, impacting agriculture and exacerbating water scarcity. Extreme weather events such as floods and storms are causing damage to infrastructure. Climate change poses a significant threat to global health, with direct consequences including severe storms, heat stress, and deteriorating air quality. Despite this uncertainty, it is imperative to adapt to the adverse effects of climate change. Rising global temperatures are contributing to more frequent and severe extreme weather events, resulting in widespread damage and loss of life. Iran's efforts to address climate change include investing in renewable energy, and implementing sustainable practices. Collaboration between the government and local communities is crucial for mitigating the effects of climate change through effective policies and initiatives. Iran aims to reduce greenhouse gas emissions and promote sustainability through investments in renewable energy and energy efficiency initiatives.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144758868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of pesticide exposure on systemic inflammatory biomarkers: a meta-analysis, and trial sequential analysis","authors":"Genesis Nayeli Fierro-Barrientos,&nbsp;Estefanía Casarrubias-González,&nbsp;Ma. Elena Moreno-Godínez,&nbsp;Eugenia Flores-Alfaro,&nbsp;Josefina Atrisco-Morales,&nbsp;Jonathan Cisneros-Pano,&nbsp;Marco Antonio Ramírez-Vargas","doi":"10.1007/s40201-025-00949-x","DOIUrl":"10.1007/s40201-025-00949-x","url":null,"abstract":"<div><p>Human pesticide exposure results in the development of several chronic diseases, including cardiometabolic, carcinogenic, neurological, and autoimmune processes. The induction of oxidative stress, subsequent tissue injury, and inflammatory response are widely accepted mechanisms related to environmental pollutants-induced diseases. In this line, several studies have been reported on the induction of systematic inflammatory state related to pesticide exposure. Nevertheless, there needs to be a consensus on the best inflammatory biomarker for measuring in response to pesticide exposure, and sources of risk of bias need to be assessed for future studies. This meta-analysis assessed whether pesticide exposure can start an inflammatory response in humans. A systematic review was performed focused on original reports that analyzed the relationship between human pesticide exposure and pro-inflammatory biomarkers. Fifteen studies were analyzed. The present meta-analysis included 3172 participants. The pooled analysis suggested that pesticide exposure can induce an inflammatory response and indicates that standardized clinical inflammatory biomarkers such as C-reactive protein are more recommended than hematological index or pro-inflammatory cytokines. Moreover, the need to consider multivariate statistical analysis is noted. The results suggested that pesticide-induced inflammatory response could be considered a mechanism through pesticide-induced diseases. These findings contribute to our understanding of the health effects of pesticide exposure and show the need for performing future studies to explore this area further, potentially leading to improved public health strategies.</p></div>","PeriodicalId":628,"journal":{"name":"Journal of Environmental Health Science and Engineering","volume":"23 2","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}