抗癌研究最新文献

{"title":"Observation on the Effect of Spontaneous Ventilation Single-Port Thoracoscopy and Conventional Thoracoscopy on T Lymphocyte Subsets and Inflammatory Factors in Patients with Non-Small Cell Lung Cancer","authors":"Hefei Li, Cuifang Liu, Yanan Wang, Shaoyong Dong, Haijiang Liao, Ce Li, Xuguang Zhang, Mo Deng","doi":"10.26689/par.v6i5.4311","DOIUrl":"https://doi.org/10.26689/par.v6i5.4311","url":null,"abstract":"Objective: To explore the effects of two types of surgical approaches, spontaneous ventilation single-port thoracoscopy and conventional thoracoscopy, on T lymphocyte subsets and inflammatory factors in patients with non-small cell lung cancer. Methods: Fifty-eight patients with non-small cell lung cancer who underwent surgery in the Affiliated Hospital of Hebei University from January 2020 to December 2021 were selected as the study subjects. All of them underwent standard lobectomy and lymph node dissection. Among them, 32 patients who underwent spontaneous ventilation single-port thoracoscopy were included in the study group, while 26 patients who underwent conventional thoracoscopy were included in the control group. The perioperative related indices, lung function, immune factor levels, and inflammatory factor levels were compared between the two groups. Results: In the study group, the perioperative incision length, intraoperative blood loss, operation time, and number of lymph node dissections were 4.28 ± 2.01, 77.89 ± 12.02, 87.21 ± 16.11, and 20.69 ± 4.45, respectively. In the control group, the perioperative incision length, intraoperative blood loss, operation time, and number of lymph node dissections were 6.32 ± 2.45, 84.98 ± 16.98, 95.88 ± 14.89, and 21.45 ± 4.36, respectively. There was no statistical difference between the study group and the control group in the number of lymph node dissections and intraoperative blood loss; the lung function in the study group was significantly better than that in the control group; the levels of T cell subsets CD4+, CD8+, CD4+/CD8+, CD16+CD56+ of the study group were 46.36 ± 5.87, 30.98 ± 4.12, 1.19 ± 0.23, and 17.41 ± 6.25, respectively, while those in the control group were 35.78 ± 4.12, 34.14 ± 3.87, 1.04 ± 0.24, and 12.45 ± 5.56, respectively; the levels of immunoglobulin IgG, IgM, and IgA of the study group were 10.45 ± 2.14, 1.21 ± 0.24, and 1.26 ± 0.25, respectively, while those of the control group were 8.78 ± 1.78, 1.06 ± 0.12, and 1.06 ± 0.26, respectively, with statistical differences; the levels of CRP, IL-6, IL-8, and TNF-? of the control group were 21.87 ± 4.26, 98.01 ± 9.58, 111.03 ± 9.96, and 123.05 ± 9.77, respectively, while those of the study group were 19.47 ± 3.89, 89.12 ± 8.96, 104.32 ± 9.12, and 112.98 ± 9.16, respectively, in which the comparison was statistically significant. Conclusion: In the surgical treatment of non-small cell lung cancer, spontaneous ventilation single-port thoracoscopic surgery has several advantages, which include less trauma and bleeding. It reduces the impact of surgical trauma on the immune function of the body, improves the postoperative lung function and inflammatory stress of the body, as well as accelerates the recovery of patients. It is an alternative to open lung lobectomy for the treatment of lung cancer.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48152182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT Differentiation of Diffuse Malignant Peritoneal Mesothelioma, Tuberculous Peritonitis, and Peritoneal Carcinomatosis","authors":"Hui Song, G. Zheng, Yue-feng Chen, Dong-liang Yang, Li Zhang, Yan-feng Xu","doi":"10.26689/par.v6i5.4206","DOIUrl":"https://doi.org/10.26689/par.v6i5.4206","url":null,"abstract":"Objective: To investigate the significance of computed tomography findings in diffuse malignant peritoneal mesothelioma (DMPeM), tuberculous peritonitis (TBP), and peritoneal carcinomatosis (PC) to differentiate the three diseases. Methods: The clinical manifestation and computed tomography scans of 147 patients with diffuse malignant peritoneal mesothelioma (n = 60), tuberculous peritonitis (n = 32), and peritoneal carcinomatosis (n = 55) were retrospectively reviewed, while taking into account of ascites, pleural plaques, viscera infiltration; abnormalities in the peritoneum; involvement of the mesentery and omentum; as well as the presence and location of enlarged lymph nodes. Results: There was no significant difference among all three groups in terms of clinical manifestation, peritoneum, omentum, and mesentery involvement, ascites, as well as the presence and location of enlarged lymph nodes. The study found that 95% of DMPeM patients had been exposed to asbestos in the past. The patients showed significant differences in the following aspects: (1) irregular peritoneum thickening, caked omentum thickening, pleural plaques, visceral infiltration, and asbestos exposure were more common in peritoneal mesothelioma patients; (2) nodular peritoneum thickening and visceral metastasis were more common in patients with peritoneal carcinomatosis; (3) smooth peritoneal thickening, pleural effusion, and extraperitoneal tuberculosis were more common in patients with tuberculous peritonitis. Conclusion: A combination of computed tomography findings could improve our ability in differentiating the three diseases.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44132278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report on Pulmonary Benign Metastasizing Leiomyoma with Recurrent Uterine Fibroids","authors":"Zheng Gong, Zegang Liu","doi":"10.26689/par.v6i5.4316","DOIUrl":"https://doi.org/10.26689/par.v6i5.4316","url":null,"abstract":"Pulmonary benign metastasizing leiomyoma (PBML) is a type of benign metastasizing leiomyoma (BML), which metastasizes to lungs. In view of the rarity and nonspecific imaging characteristics of PBML, this condition is easily misdiagnosed as malignant lung cancer. This is a case report of a 39-year-old lady in whom multiple bilateral lung nodules were found during a health checkup and was diagnosed with PBML. The patient had recurrent uterine fibroids and underwent myomectomy twice, 7 years and 3 years ago, respectively, before the diagnosis of PBML was made. This patient was asymptomatic, and regular examinations were normal. Her laboratory investigations were all within normal range. Computed tomography (CT) showed multiple nodules in bilateral lungs. In order to confirm the disease, thoracoscopic nodule resection and tissue biopsy were performed. Hematoxylin eosin (HE) staining showed spindle-shaped cells, while immunohistochemical staining revealed positive for desmin, smooth muscle actin (SMA), estrogen receptor (ER), and progesterone receptor (PR), which are all PBML markers. The patient was followed-up without any further treatment. After 8 months of follow-up, CT scan revealed an increased number of nodules. This is unique case because of the recurrence of uterine fibroids, which means that the patient is susceptible to it. Our report may give a new insight to the relationship between the susceptibility of uterine fibroids and the onset and progression of PBML.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44816448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of Helper T Cell Type 17 and CD4+ CD25+ Tregs in AMA-M2 Positive PBC Patients","authors":"T. Cai, Yang Yu, Xiuzhong Liu, Zhanliang Chen, Lin Duan","doi":"10.26689/par.v6i5.4357","DOIUrl":"https://doi.org/10.26689/par.v6i5.4357","url":null,"abstract":"Objective: To investigate the expression and impact of helper T cell type 17 and CD4+ CD25+ regulatory T (Treg) cells in anti-mitochondrial M2 antibody (AMA-M2) positive primary biliary cholangitis (PBC) patients. Methods: Thirty PBC patients with positive AMA (M2 type) (antibody titer above 1:320) by indirect immunofluorescence assay under the Affiliated Hospital of Hebei University from November 2021 to August 2022 were selected as the experimental group, while 30 healthy individuals were selected as controls. The subjects were observed and analyzed for AFP-L3 and immunoglobulin expression. Results: The levels of Thl7, Treg, Thl7/Treg, interleukin (IL)-17A, IL-2, IL-10, and transforming growth factor (TGF)-?1 cytokines of the experimental group were 2.61 ± 0.48, 1.15 ± 0.54, 2.41 ± 0.47, 310.94 ± 21.14, 276.36 ± 36.12, 317.89 ± 28.97, and 197.48 ± 31.04, respectively, while those of the control group were 1.14 ± 0.58, 0.88 ± 0.29, 1.47 ± 0.25, 9.69 ± 1.26, 57.69 ± 2.45, 154.01 ± 19.87, and 514.36 ± 36.12, respectively, wherein P < 0.05; the CD4+, CD8+, and CD4+/CD8+ of the experimental group were 39.48 ± 4.19, 20.12 ± 4.41, and 1.76 ± 0.14, respectively, while those of the control group were 35.78 ± 4.21, 22.01 ± 4.16, and 1.51 ± 0.13, respectively, wherein P < 0.05. Conclusion: In patients with PBC, there is a significant imbalance in Thl7/Treg cells. Il-17A, IL-2, IL-10, and TGF- ?1 cytokines play important roles in the differentiation and functional expression of both Thl7 and Treg cells.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42093926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism of SNHG12 in Regulating Human Angiostatin Binding Protein Through MicroRNA-497 in the Migration and Invasion of Human Lung Cancer Cells","authors":"Yang Yu, Yan Wang, Tianhong Jia, Wei Li, Xiaoxue Huang","doi":"10.26689/par.v6i5.4336","DOIUrl":"https://doi.org/10.26689/par.v6i5.4336","url":null,"abstract":"Objective: To investigate the effect of small nucleolar host gene 12 (SNHG12) on the migration and invasion of human lung cancer cells by regulating human angiostatin binding protein through microribonucleic acid (microRNA)-497. Methods: A549, H1299, and PC9 cells were cultured in Roswell Park Memorial Institute (RPMI)-1640 medium containing 10% fetal bovine serum, and human bronchial epithelial (HBE) cells were cultured in Dulbecco’s modified eagle medium (DMEM) containing 10% fetal bovine serum. The incubator conditions were as follows: saturated humidity, 37?, and 5% carbon dioxide (CO2). Results: The gene expressions of small nucleolar host gene 12 (SNHG12) in HBE, A549, H1299, and PC9 were 1.00 ± 0.02, 5.61 ± 0.42, 3.78 ± 0.29, and 3.51 ± 0.23, respectively. The gene expressions of microRNA-497HBE, A549, H1299, and PC9 were 1.00 ± 0.13, 0.21 ± 0.04, 0.35 ± 0.05, and 0.37 ± 0.06, respectively, with P < 0.05. The microRNA-497 gene expression and cell apoptosis rate in the microRNA-497 group and the microRNA-497 + pcDNA3.1 group were significantly higher than those in the miR-NC group, whereas the A value and cell invasion number were significantly lower than those in the miR-negative control (NC) group, with P < 0.05. Compared with the microRNA-497 + pcDNA3.1 group, the microRNA-497 gene expression and cell apoptosis rate in the microRNA-497 + SNHG12 group were significantly lower, whereas the A value and cell invasion number were significantly higher, with P < 0.05. Conclusion: SNHG12 can inhibit the migration and invasion of human lung cancer cells by regulating human angiostatin binding protein through microRNA-497.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45280294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research Progress of Prostate Stem Cell Antigen in Bladder Cancer Treatment","authors":"Jinmei Li, Runfen Cheng, Bi-Yun Zhou, Zhiqiang Zhang, Q. Zhai, Jinku Zhang","doi":"10.26689/par.v6i5.4337","DOIUrl":"https://doi.org/10.26689/par.v6i5.4337","url":null,"abstract":"In order to study the application effect of prostate stem cell antigen in the treatment of bladder cancer, several literatures have been reviewed in this paper, including the predisposition factors of bladder cancer, clinical treatment methods, progress of prostate stem cell antigen, and nanomaterial probe. This paper presents a feasible method of using luminescent nanomaterials (anti-UCNPs) as biological probes.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45777242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanism of Ginsenoside Rh1 in Regulating Breast Cancer Cell Extravasation Based on CCL20-CCR6","authors":"Wenming Zhao, B. Zhou, Jirui Sun, Haizhi Qiao, Shu-Xin Ma, Xu Wang, Jinku Zhang, Jinmei Li","doi":"10.26689/par.v6i5.4353","DOIUrl":"https://doi.org/10.26689/par.v6i5.4353","url":null,"abstract":"Objective: To explore the regulatory mechanism of ginsenoside Rh1 on breast cancer cell extravasation based on CCL20-CCR6. Methods: In 2021, a total of 34 patients with breast cancer were treated in Baoding First Central Hospital. During hospitalization, pathological examinations were performed, and all the patients were diagnosed with invasive ductal carcinoma. Out of the 34 cases, 16 cases were found to have CCR6 expression in breast cancer tissues, in which they were recorded as the CCR6 expression group, whereas 18 cases did not have CCR6 expression; these cases were recorded as the CCR6 non-expression group. During the same period, 21 normal patients were selected as the control group. The peripheral blood CCL20 level and the expression of CCR6 on the surface of CD3+ T lymphocytes were analyzed. The extracts of cancer cells were collected, purified, and cultured, and the effect of ginsenoside Rh1 on the invasion and metastasis of breast cancer cells was analyzed. Results: The peripheral blood CCL20 level in the CCR6 expression group was significantly higher than that in the CCR6 non-expression group and the control group, in which p < 0.05, indicating that the difference was statistically significant; at 12, 24, and 48 hours, the cell survival rate of each dose group was significantly higher than that of the blank control group and the dimethyl sulfoxide (DMSO) group (p < 0.05). At 48 hours, comparing the low-dose group with the high-dose group, the cell survival rate significantly decreased (p < 0.05). Compared with the blank control group and DMSO group, the invasion ability of breast cancer cells could be reduced in both, high- and medium-dose groups, where p < 0.05, indicating that the difference was statistically significant. Conclusion: CCL20 may play a role in the pathogenesis of certain breast cancers, and ginsenoside Rh1 can effectively regulate the invasion and migration of breast cancer cells.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49254684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression and Clinical Significance of miRNA-495 in the Peripheral Blood of Acute Myeloid Leukemia Patients","authors":"Ling-juan Huang, Jin-qian Dai","doi":"10.26689/par.v6i5.4279","DOIUrl":"https://doi.org/10.26689/par.v6i5.4279","url":null,"abstract":"Objective: To analyze the expression and clinical significance of miRNA-495 in the peripheral blood of patients with acute myeloid leukemia. Methods: Fifty-six patients with acute myeloid leukemia and 56 healthy controls were selected. Fasting venous blood was drawn and centrifuged, and the plasma was collected. The target miRNA was directly amplified and reverse transcribed into cDNA. The expression of plasma miR-495 was detected by qRT-PCR. Results: The expression level of miRNA-495 in newly diagnosed acute myeloid leukemia (AML [ND]) and relapsed/refractory acute myeloid leukemia (AML [RR]) was significantly lower than that in complete remission (AML [CR]) and normal control group (Control) (p < 0.0001). There was no significant difference between AML (ND) group and AML (RR) group (p > 0.05). The area under the ROC curve (AUC) of miRNA-495 was 0.9503, the 95% confidence interval was 0.9113–0.9892 (p < 0.0001), the standard error was 0.020, the sensitivity and specificity were 91.1% and 92.9%, respectively, and the Jordan index was 0.857. There was no significant difference between the expression level of miRNA-495 and gender, age, leukocyte count, hemoglobin, and platelet count (p > 0.05). However, it was found related to the proportion of primitive bone marrow cells in patients (p = 0.017). Conclusion: The decreased expression of plasma miR-495 in AML patients can be used as a new indicator for the diagnosis and prognosis of AML.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46754766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Prognosis of Venetoclax Combined with Hypomethylating Agents in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia","authors":"Lan Li, Weihua Zhang","doi":"10.26689/par.v6i5.4226","DOIUrl":"https://doi.org/10.26689/par.v6i5.4226","url":null,"abstract":"Objective: To investigate the efficacy and prognosis of venetoclax combined with hypomethylating agents (HMAs) in the treatment of relapsed/refractory acute myeloid leukemia (AML). Methods: From June 2021 to February 2022, 14 patients with relapsed/refractory AML were treated with venetoclax combined with HMAs, among which nine patients were treated with venetoclax + azacytidine, while five patients were treated with venetoclax + decitabine. The efficacy of the treatments was observed, and the patients were followed up. Results: All patients received one to five courses of treatment, in which the median course of treatment was three; four cases achieved CR and another four achieved PR, with NR in six cases; there was no treatment-related death. There were seven deaths up to the end of the follow-up period, all of which were progressive deaths at the end of the disease, and the overall survival rate was 50.00%. All the patients experienced different degrees of nausea, vomiting, and myelosuppression (Grade II–IV), nine patients had Grade 3–4 hematological adverse reactions, and seven patients had infection. Conclusion: Venetoclax combined with hypomethylating agents is effective in the treatment of relapsed/refractory AML, with good prognosis, and some patients may even achieve CR. Although bone marrow suppression is serious with this combination, it is well tolerated.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48625873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of a Multidisciplinary Collaborative Model for the Diagnosis and Treatment of Vertigo","authors":"Gui-sheng Zhang, Hui-Fen Xia, Qi Wang, Yuan Wang, Zhanning Qi, Ruiqing Yan","doi":"10.26689/par.v6i5.4264","DOIUrl":"https://doi.org/10.26689/par.v6i5.4264","url":null,"abstract":"Objective: To investigate the effectiveness of applying a multidisciplinary collaborative model for the diagnosis and treatment of patients with vertigo. Methods: The study was carried out in Xianyang Hospital of Yan’an University, in which 100 patients with vertigo were selected from April 2021 to April 2022 and were divided into two groups: the control group was under the single diagnosis and treatment model, whereas the experimental group was under the multidisciplinary collaborative diagnosis and treatment model, with 50 cases in each group. The diagnostic effects of the two groups were compared. Results: The diagnostic and therapeutic efficiency of the patients in the experimental group were 94% and 98%, respectively, while those of the patients in the control group were 78% and 82%, respectively, with a significant difference between the two groups (p < 0.05). The balance scores of the patients in both groups were low before the treatment, in which the difference was not significant (p > 0.05); after the treatment, the scores improved, with those of the patients in the experimental group being significantly higher than those in the control group (p < 0.05). Moreover, the satisfaction rate of patients in the experimental group (98%) was significantly higher than that of the control group (80%) (p < 0.05). Conclusion: The application of the multidisciplinary collaborative diagnosis and treatment model in the diagnosis of patients with vertigo is effective. The multidisciplinary model can improve clinical diagnosis, enhance the treatment effect, improve the clinical symptoms of patients, and increase the satisfaction of patient care. Hence, it is of high clinical application value.","PeriodicalId":61025,"journal":{"name":"抗癌研究","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44740338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}