Journal of Applied Spectroscopy最新文献_第3页

Polarization Switching Mechanism in Semiconductor Surface-Emitting Lasers 半导体表面发射激光器的偏振开关机制

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02055-8

L. I. Burov, E. S. Voropay

引用次数: 0

Study on the Experimental Accuracy of Raman Spectral Parameters 拉曼光谱参数实验精度研究

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02070-9

Binoy Krishna De, Pragati Sharma, Divya Jangra, Praveen Kumar Velpula, Vasant G. Sathe

{"title":"Study on the Experimental Accuracy of Raman Spectral Parameters","authors":"Binoy Krishna De, Pragati Sharma, Divya Jangra, Praveen Kumar Velpula, Vasant G. Sathe","doi":"10.1007/s10812-026-02070-9","DOIUrl":"10.1007/s10812-026-02070-9","url":null,"abstract":"Raman spectroscopy is considered an essential spectroscopic technique due to its simplicity, nondestructive nature, and ability to provide molecular fingerprinting. These qualities make it applicable across numerous research fields. Accurate Raman data analysis can uncover remarkable sub-microscopic phenomena such as local structural changes, electron–phonon and spin–phonon coupling, and ionic displacements. Therefore, understanding the precision involved in collecting and analyzing Raman data has become critically important. Omitting proper calibration and validation methods can lead to significant errors. In this article, we present a study on how improper validation methods of a spectrometer and inaccurate data fitting can cause substantial inaccuracies in spectral parameters. We demonstrate that the accuracy of Raman spectral parameters heavily relies on the spectrometer's validation process, the choice of fitting function, and the consideration of errors caused by instrument randomness and resolution. Additionally, our study offers a method for assessing the uncertainty of Raman spectral parameters for a given spectrometer system. This is crucial for optimization, especially when dealing with subtle changes in spectral parameters to reduce inaccuracies.","PeriodicalId":609,"journal":{"name":"Journal of Applied Spectroscopy","volume":"93 1","pages":"141 - 149"},"PeriodicalIF":1.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Creation of an Optical Profile Diffraction Grating Made with Nanoporous Germanium by Sputtering with Bismuth Ions 用铋离子溅射制备纳米多孔锗衍射光栅

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02066-5

A. L. Stepanov, A. M. Rogov, V. F. Sotnikova, V. F. Valeev, V. I. Nuzhdin, D. A. Konovalov

引用次数: 0

Analytical Quality by Design Assisted Spectroscopic Method Development for Estimation of Clevidipine Butyrate in Synthetic Mixture in Application to Greenness Study 设计辅助光谱法评价合成混合物中丁酸氯维地平的分析质量及其在绿色研究中的应用

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02071-8

Shrutika Desai, Rohan Mane, Ajay Munde, Pranabesh Sikdar, Charu Chandrakant Mehta

{"title":"Analytical Quality by Design Assisted Spectroscopic Method Development for Estimation of Clevidipine Butyrate in Synthetic Mixture in Application to Greenness Study","authors":"Shrutika Desai, Rohan Mane, Ajay Munde, Pranabesh Sikdar, Charu Chandrakant Mehta","doi":"10.1007/s10812-026-02071-8","DOIUrl":"10.1007/s10812-026-02071-8","url":null,"abstract":"Two simple, rapid, cost-effective, precise, and accurate UV spectrophotometric methods have been developed for the estimation of Clevidipine butyrate, a dihydropyridine calcium channel blocker and antihypertensive agent, using an analytical quality by design approach. The characterization of Clevidipine butyrate was performed by melting point, differential scanning calorimetry, and FT-IR techniques. Using the analytical quality-by-design approach, the critical method variables selected were scanning speed and sampling interval via Central Composite Design, which demonstrated the work's resilience and optimised methodology. A method for UV spectroscopy was developed using two methods — method I, based on the maxima absorption method of zero-order spectrophotometrics with λmax of 238 and 362 nm, and method II, based on the zero-order area under curve method, wavelength range 233–243 and 353–371 nm, respectively. Both the developed methods were subjected to validation as per the guidelines set by the ICH. The methods showed good linearity in the concentration, ranging from 2 to 12 μg/mL, while the % Recovery of the developed methods was in a range of 98.41–100%. The methods showed good sensitivity and appropriate precision with an RSD less than 2%, and the methods were applied for determination of the Clevidipine synthetic mixture. The developed method's greenness profile was evaluated and compared using the AGREE and MoGAPI tools and were found to be in compliance with twelve principles of green analytical chemistry.","PeriodicalId":609,"journal":{"name":"Journal of Applied Spectroscopy","volume":"93 1","pages":"158 - 169"},"PeriodicalIF":1.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eco-Friendly UV Spectroscopic Method for Precise Quantification of Daprodustat in Pharmaceuticals 生态友好型紫外光谱法精确定量药品中达伐他汀

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02069-2

Shreya Deshmukh, Priti Mohite, Shreyas Talim, Yash Jaiswal, Dhrruv Shah, Aditya Umrethwala, Sanjay Sharma

{"title":"Eco-Friendly UV Spectroscopic Method for Precise Quantification of Daprodustat in Pharmaceuticals","authors":"Shreya Deshmukh, Priti Mohite, Shreyas Talim, Yash Jaiswal, Dhrruv Shah, Aditya Umrethwala, Sanjay Sharma","doi":"10.1007/s10812-026-02069-2","DOIUrl":"10.1007/s10812-026-02069-2","url":null,"abstract":"Daprodustat is a new hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) and a novel medication for treating chronic kidney disease anaemia. Daprodustat boosts endogenous erythropoietin production, regulates iron metabolism, and is an alternative erythropoiesis-stimulating agent. The aim of this study is to develop and validate a simple, accurate, and environmentally friendly ultraviolet (UV) spectroscopic method for the quantitative analysis of daprodustat in pharmaceutical formulations. The UV spectrophotometric method was prepared using methanol as the solvent and validated according to the International Council for Harmonisation (ICH) Q2 (R2) guidelines. The process was tested for linearity, precision, accuracy, robustness, limit of detection (LOD), and quantification (LOQ). Daprodustat showed maximum absorbance λmax = 261.45 nm in methanol. The linearity range was 4–16 μg/mL, with a regression equation of y = 0.0577x + 0.0477 and a correlation coefficient R2 = 0.9983. The procedure demonstrated excellent precision (relative standard deviation (%RSD) < 2%) and recovery at 98–99%. The LOD and LOQ were 0.672 μg/mL and 2.0 μg/mL, respectively. The new UV spectrophotometric method for quantifying daprodustat in solid dispersions proved simple, accurate, and precise. Environmental sustainability was assessed using Analytical GREEness (AGREE) and the Green Analytical Procedure Index (GAPI). Accordingly, this validated UV spectroscopic method can be effectively used for routine quality control analysis of daprodustat in solid dispersions, providing a cost-effective and sustainable approach to analytical evaluation.","PeriodicalId":609,"journal":{"name":"Journal of Applied Spectroscopy","volume":"93 1","pages":"150 - 157"},"PeriodicalIF":1.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Derivative Spectrophotometric Methods for Estimation of Seratrodast in Bulk and in Formulation 原料药和制剂中舍曲司特的导数分光光度法测定

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02072-7

Kanade Krushna Devrao, Alka Bali, Priyanshi Sharma

{"title":"Derivative Spectrophotometric Methods for Estimation of Seratrodast in Bulk and in Formulation","authors":"Kanade Krushna Devrao, Alka Bali, Priyanshi Sharma","doi":"10.1007/s10812-026-02072-7","DOIUrl":"10.1007/s10812-026-02072-7","url":null,"abstract":"Seratrodast is a 1,4-benzoquinone derivative belonging to the class of thromboxane A2 (TXA2) receptor antagonists and is employed for prophylactic management of asthma. The present report describes the validation of quick, simple, sensitive, and cost-effective zero-order, first-order, and second-order derivative spectrophotometric methods for the estimation of seratrodast in bulk and in its marketed tablet formulation. Exhaustive spectrophotometric analysis of the drug was carried out using a total of 23 parametric variations, which were evaluated in acetonitrile. Three selected method variants were assessed for their stability, indicating potential regarding stress-degraded solutions of the drug. The developed methods were validated with respect to linearity, accuracy, precision, and robustness. Excellent linearity was observed in the concentration range of 5.0–50.0 μg/mL with correlation coefficients above 0.999. The limits of detection were found to range from 0.54 to 0.70 μg/mL, and quantitation limits ranged from 1.66 to 2.14 μg/mL for the proposed method variants. The proposed methods were also employed for the assay of seratrodast in its marketed tablet formulation, and good recoveries ranging from 96.23 to 98.68% were obtained.","PeriodicalId":609,"journal":{"name":"Journal of Applied Spectroscopy","volume":"93 1","pages":"170 - 177"},"PeriodicalIF":1.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multipass Excitation System for Raman Spectroscopy of Gases 气体拉曼光谱的多通激发系统

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02065-6

M. A. Kostenko, D. V. Petrov

引用次数: 0

Effect of ZnO Nanoparticles Dispersed in p–n-Undecyloxy Benzoic Acid Liquid Crystalline Compounds: Optical and Order Parameter Studies ZnO纳米粒子在对- n-十一酰基苯甲酸液晶化合物中的分散效应：光学和序参量研究

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02078-1

P. Jayaprada, R. K. N. R. Manepalli, K. Koteswara Rao, M. C. Rao, T. Satyanarayana, Y. Subbareddy, N. Usha Rani, Ravindranadh Koutavarapu, M. Tanooj Kumar

{"title":"Effect of ZnO Nanoparticles Dispersed in p–n-Undecyloxy Benzoic Acid Liquid Crystalline Compounds: Optical and Order Parameter Studies","authors":"P. Jayaprada, R. K. N. R. Manepalli, K. Koteswara Rao, M. C. Rao, T. Satyanarayana, Y. Subbareddy, N. Usha Rani, Ravindranadh Koutavarapu, M. Tanooj Kumar","doi":"10.1007/s10812-026-02078-1","DOIUrl":"10.1007/s10812-026-02078-1","url":null,"abstract":"This paper presents the optical and order parameter studies of a mixture of liquid crystalline (LC) materials, such as p–n-undecyloxy benzoic acid (11OBA), including the incorporation of zinc oxide (ZnO) nanoparticles (NPs) at different weight concentrations (0.5–2 wt.%). Studies, including optical absorption, photoluminescence (PL), birefringence, refractive indices, and order parameters, were undertaken on the prepared samples. A prominent absorption peak was observed approximately at 235 nm for both the pure and nano-dispersed liquid crystal samples. The PL spectra exhibit two distinct peaks, located at 367 and 618 nm, whereas ZnO NPs dispersed 11OBA showed a single peak at 392 nm. The peak observed at 367 nm is attributed to near-band-edge emission of free excitons, whereas the peak at 618 nm is indicative of deep-level emission, resulting from point defects such as vacancies and interstitials within the bandgap. The order of parameter values are also calculated for the mixture of the 11OBA LC compound dispersed with ZnO NPs using different models like Kuczynksi, Haller extrapolation, effective geometry, and Vuks at a stabilized nematic region in the visible range at 460-, 500-, 570-, and 635-nm wavelengths.","PeriodicalId":609,"journal":{"name":"Journal of Applied Spectroscopy","volume":"93 1","pages":"226 - 237"},"PeriodicalIF":1.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breathing Dynamics of Cosh-Gaussian Laser Beams in Cubic-Quintic Media with Axially Modulated Quintic Nonlinearity cosh -高斯激光束在三次五次轴向调制五次非线性介质中的呼吸动力学

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02068-3

A. K. Alex, D. Kumar, N. Gupta

引用次数: 0

New Approach to Tuning the Scintillation Parameters of PBWO4 Crystals to Expand the Energy Range for γ-ray Detection 调整PBWO4晶体闪烁参数以扩大γ射线探测能量范围的新方法

IF 1 4区化学

Journal of Applied Spectroscopy Pub Date : 2026-02-27 DOI: 10.1007/s10812-026-02067-4

M. V. Korzhik, E. A. Amelina, M. A. Artemyeva, L. A. Balyan, A. G. Bondarau, A. N. Vasil’ev, V. D. Grigorieva, A. P. Eliseyev, A. B. Kuznetsov, I. Yu. Komendo, V. A. Mechinsky, A. L. Mikhlin, A. G. Postupaeva, V. N. Shlegel

{"title":"New Approach to Tuning the Scintillation Parameters of PBWO4 Crystals to Expand the Energy Range for γ-ray Detection","authors":"M. V. Korzhik, E. A. Amelina, M. A. Artemyeva, L. A. Balyan, A. G. Bondarau, A. N. Vasil’ev, V. D. Grigorieva, A. P. Eliseyev, A. B. Kuznetsov, I. Yu. Komendo, V. A. Mechinsky, A. L. Mikhlin, A. G. Postupaeva, V. N. Shlegel","doi":"10.1007/s10812-026-02067-4","DOIUrl":"10.1007/s10812-026-02067-4","url":null,"abstract":"The introduction of strontium ions into lead tungstate PbWO4 (PWO) was shown to permit broad variation of the scintillation light yield, temperature dependence of this yield, and the luminescence kinetics; the strontium ions isomorphically replace lead ions in the crystal lattice. With 10% substitution of the lead ions in the crystal lattice, (Pb,Sr)WO4 has a scintillation light yield of 1000 ph/MeV (ph = photons) and a predominant constant of scintillation decay kinetics of 40 ns, while the temperature dependence of scintillation yield is close to that for the initial PWO material. On the other hand, the scintillation light yield reaches 10,000 ph/MeV in the compound with 80% strontium replacing lead and the decay constant is 600 ns. In this case, the scintillation light yield at 300–400 K is characterized by a temperature coefficient equal to –0.6 K. The compound with 10% strontium is of interest for highenergy physics experiments including spectroscopy starting from 10 MeV without detector cooling. The compound with 80% strontium holds promise for use in spectroscopy for geological exploration and well logging, where work at elevated high temperatures is required.","PeriodicalId":609,"journal":{"name":"Journal of Applied Spectroscopy","volume":"93 1","pages":"121 - 126"},"PeriodicalIF":1.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147561759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0