Journal of Analytical Chemistry最新文献

{"title":"Application of Ensemble Machine Learning Methods to the Classification and Interpretation of Raman Spectra of Adipose Tissue During Enzymatic Hydrolysis by Lipase","authors":"E. S. Prikhozhdenko","doi":"10.1134/S1061934826700516","DOIUrl":"10.1134/S1061934826700516","url":null,"abstract":"<p>Raman spectroscopy (<b>RS</b>) in combination with machine learning methods was used to solve the problem of the classification of adipose tissue before and after exposure to lipase. Differences between the classes were identified using principal component analysis. Hyperparameters such as the number of trees (n_estimators) and the maximum depth (max_depth) of the random forest (<b>RF</b>) and gradient boosting (<b>GB</b>) ensemble models are optimized for balanced accuracy and training time. This made ensured obtaining models with high predictive ability. In this method, models with 50 decision trees with a maximum depth of 3 were trained. The weighted accuracies of the RF and GB models were 96.4 ± 8.7% and 92.9 ± 11.3%, respectively. While the final prediction of the RF model was affected by intensities at 37 wavenumbers, including those corresponding to vibrations of the C=C bonds of unsaturated fatty acids, as well as of aliphatic C−C bonds and the carbonyl group &gt;C=O, the prediction of the GB was based predominantly on the intensity at 1650 cm⁻¹ (C=C, importance 95.4%). The results obtained are consistent with the formation of free fatty acids, mono- and diglycerides as a result of the enzymatic hydrolysis of adipose tissue.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"1110 - 1117"},"PeriodicalIF":1.5,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148652193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of Multichannel Microgravimetry for Assessing the Properties of Organic Phosphors of the Azolotriazine Class","authors":"T. A. Kuchmenko,&nbsp;D. Yu. Vandyshev,&nbsp;S. A. Kalabukhov","doi":"10.1134/S1061934826700589","DOIUrl":"10.1134/S1061934826700589","url":null,"abstract":"&lt;p&gt;The article is devoted to the use of multichannel microgravimetry for assessing the functional properties of organic phosphors of the azolotriazine class as promising analytical reagents for test systems for liquid and gas media. The promise of using azolotriazines of various structures as analytical reagents in test systems for liquid and gas media is estimated. The primary objectives of the study were to identify the most stable and selective structures of the synthesized organic compounds based on heterocyclic ring systems of imidazo-, pyrazolo-, and triazolotriazines; to assess their properties and potential use as analytical reagents for volatile organic and some inorganic (water, ammonia) compounds (&lt;b&gt;VCs&lt;/b&gt;) for use in portable test systems. The study covered two fields: the assessment of changes in the optical properties of the reagents in various media (solutions, solid substrates) for visual test systems, and an analysis of the kinetics of sorption of VC vapors by piezoelectric quartz resonators (FLU-1 array) modified with fluorimetric reagents in the injection and frontal sample introduction modes in combination with highly sensitive microgravimetry. Compounds of the highest stability in solution and on a solid support (4-(6-oxo-2-phenylimidazo[1,2-&lt;i&gt;b&lt;/i&gt;]pyrido[4,3-&lt;i&gt;e&lt;/i&gt;][1,2,4]triazin-7(6&lt;i&gt;H&lt;/i&gt;)-yl)butanoic acid (&lt;b&gt;I)&lt;/b&gt;, 3-hydroxy-2-(6-oxo-2-phenylimidazo[1,2-&lt;i&gt;b&lt;/i&gt;]pyrido[4,3-&lt;i&gt;e&lt;/i&gt;][1,2,4]triazin-7(6&lt;i&gt;H&lt;/i&gt;)-yl)propanoic acid, 3-methyl-6-phenylimidazo[1,2-&lt;i&gt;b&lt;/i&gt;][1,2,4]triazine-2-carbohydrazide) were identified, as well as those demonstrating selectivity to the key analytes formed during food spoilage, i.e., butyric acid, propionic aldehyde, cyclohexanone, and aromatic amines. The results indicate that azolotriazines ensure the differential recognition of complex VC mixtures, including real samples, by interpreting paired sensitivity spectra &lt;i&gt;A&lt;/i&gt;(&lt;sub&gt;&lt;i&gt;i&lt;/i&gt;/&lt;i&gt;j&lt;/i&gt;&lt;/sub&gt;) and kinetic “visual fingerprints” of the signals of sensor with the selected best phases.\u0000A chemometric RGB space method with integral color labels of the results of vapor detection by piezoelectric quartz microbalances with new sorbents confirmed the applicability of compounds &lt;b&gt;I&lt;/b&gt; and 7-(2-aminophenyl)pyrazolo[5,1-&lt;i&gt;c&lt;/i&gt;]pyrido[4,3-&lt;i&gt;e&lt;/i&gt;][1,2,4]triazin-6(7&lt;i&gt;H&lt;/i&gt;)-one to the identification of water, ethanol, and organic acids. However, to ensure the accuracy of an analysis, it is important to completely remove residual polar solvents (DMSO) affecting phase selectivity.\u0000A protocol was proposed for the rapid screening of luminophore, with the assessment of visual brightness, stability, and gravimetric vapor weighing efficiency under both batch and dynamic conditions. This step confirmed the feasibility of integrating individual azolotriazines into sensor platforms for monitoring the quality of food and biomedical systems and indicated a direction for optimizing the structures of potential reagents by adjusting donor–acceptor","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"1174 - 1189"},"PeriodicalIF":1.5,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148652194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation of Homogeneous Luminophores from Citric Acid and Ethylenediamine-Based Carbon Dots: pH Dependence of Their Optical Properties","authors":"A. A. Korepanova,&nbsp;K. A. Laptinskiy,&nbsp;T. A. Dolenko","doi":"10.1134/S1061934826700577","DOIUrl":"10.1134/S1061934826700577","url":null,"abstract":"<p>Studying the structure and mechanisms of photoluminescence (<b>PL</b>) formation in carbon nanoparticles, particularly carbon dots (<b>CDs</b>), is a topical issue in various fields of nanosensors. A key step in solving this problem is obtaining a homogeneous solution of the synthesized nanoparticles. In this study, two types of CDs with different ratios of ethylenediamine (<b>EDA</b>) and citric acid (<b>CA</b>) precursors are synthesized using a hydrothermal method. The synthesized CDs are separated into fractions using gel electrophoresis. It is found that the photoluminescence, optical density, and PL lifetime of the isolated CD fractions synthesized from EDA and CA depend significantly on the pH of the water. A theory is put forward that changes in the spectral characteristics of CD fractions with pH are due to the protonation/deprotonation of imidazole amino groups in the luminophores of these fractions.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"1163 - 1173"},"PeriodicalIF":1.5,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148652256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trace Quantification of Flavonoids in Fruit and Vegetable Juices via Stir Bar Sorptive Extraction Using Carbon Nanotubes Modified by Grafted Poly(Ethylene Glycol)","authors":"Nadiya Ekbatani Amlashi,&nbsp;Shayan Dadgarnejad,&nbsp;Abbas Maleki,&nbsp;Mohammad Reza Hadjmohammadi","doi":"10.1134/S1061934826700449","DOIUrl":"10.1134/S1061934826700449","url":null,"abstract":"<p>This study introduces a novel analytical approach for the trace quantification of antioxidant flavonoids, namely quercetin, morin, and apigenin, which are naturally present in a wide variety of fruit and vegetable juice samples. For the first time, stir bar sorptive extraction (<b>SBSE</b>) was implemented as a solid-phase microextraction technique for the direct isolation of flavonoids from complex natural juice matrices. The extraction phase was developed by modifying multi-walled carbon nanotubes through the grafting of poly(ethylene glycol) bearing carboxyl groups, which significantly enhanced the surface functionality and provided strong and selective interactions with the target analytes. Following the extraction step, the retained flavonoids were efficiently desorbed into a suitable organic solvent and quantified by high-performance liquid chromatography under optimized detection conditions. To further strengthen the analytical performance, a systematic experimental design and chemometric optimization strategy were employed. This approach allowed for the precise identification and fine-tuning of influential variables, such as extraction time, desorption solvent, and stirring rate, leading to improved sensitivity and reproducibility while minimizing experimental effort. Under optimized conditions, the developed method demonstrated a wide linear calibration range extending from 0.10 to 20 000 ng/mL, with correlation coefficients consistently above 0.999. The validated protocol yielded excellent recoveries exceeding 90% and relative standard deviations below 1.5%. Collectively, these results highlight the high reliability, robustness, and novelty of the proposed SBSE-based methodology, which represents a promising tool for the routine determination of antioxidant flavonoids in real fruit and vegetable juice samples.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"998 - 1006"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148349747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gold Nanoparticle—Fluorescent Dye Conjugates for Bioanalyte Detection: a Review","authors":"Anudevi Sumathi Devadass,&nbsp;Shoba Narayan","doi":"10.1134/S1061934825603731","DOIUrl":"10.1134/S1061934825603731","url":null,"abstract":"<p>Gold nanoparticles (<b>GNP</b>s) have unique features based on their size-dependent optical properties, such as localized surface plasmon resonance, enhancing spectroscopic signal output and improving their utility in biosensing and bio-analytical detection. These plasmonic fields produced by GNPs enhance the local electromagnetic environment, increasing the excitation and emission efficiency of nearby fluorophores. When functionalized with fluorescent dyes, conjugated GNPs provide a highly selective and sensitive method for biomolecule detection. The method uses the functionalization of the GNPs with fluorescent dye molecules, as well as mechanisms such as metal-enhanced fluorescence, which make use of fluorescence quenching and Forster resonance energy transfer. GNPs-functionalized fluorescent dye biosensors possess excellent features in terms of sensitivity, real-time monitoring, cost-effectiveness, and miniaturization compared to real methods such as polymerase chain reaction or enzyme-linked immunosorbent assay. The use of green synthesis, microfluidic integration, and point-of-care methods contributes to their practical deployment. This review focuses on the synthesis, surface functionalization, and sensing processes of fluorescence dye conjugates to GNPs and provides insight into how these conjugates improve fluorescence-based assays for the detection of bioanalytes.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"977 - 997"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148349711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic Solid-Phase Extraction and Preconcentration of Anionic Azo Dyes: A Review","authors":"K. O. Andreeva,&nbsp;V. I. Savrasova,&nbsp;S. S. Aleksenko,&nbsp;Yu. A. Tyunina,&nbsp;S. A. Shalabai,&nbsp;S. N. Shtykov","doi":"10.1134/S1061934826700383","DOIUrl":"10.1134/S1061934826700383","url":null,"abstract":"<p>An analysis of the data published in the last decade on the use of magnetic nanoparticles (<b>MNP</b>s<b>)</b> modified with inorganic, organic, and polymeric substances for the sorption and preconcentration of anionic azo compounds used as indicators, organic reagents, food and textile dyes in water media and also in food and environmental samples is presented. The main focus is on the revelation of the effect of the modifier nature and sorption conditions (pH; dye concentration; MNP weight, specific surface area, pore diameter, and volume; zeta potential; and magnetization value) on the recovery, sorption and desorption time, and also on the sorption capacity of the MNPs with respect to various acidic mono- and bisazo dyes. The main trends in the development of methods of magnetic solid-phase extraction are noted.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"891 - 917"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148349715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liquid Micellar-Saturated Phases of Surfactants as Test Agents for the Determination of Phenols","authors":"E. I. Tsyguleva,&nbsp;S. Yu. Doronin","doi":"10.1134/S1061934826700450","DOIUrl":"10.1134/S1061934826700450","url":null,"abstract":"<p>This paper presents a comparative analysis of the preconcentration and subsequent test determination of phenol and some of its derivatives (resorcinol, phloroglucinol, thymol, 1-, 2-naphthols) at the MAC level using micellar-saturated phases of nonionic surfactants (their mixtures with cationic surfactants) using homogeneous liquid microextraction of analytical forms formed by reactions of analytes with 4-nitrophenyldiazonium, 4-aminoantipyrine, and the Folin–Ciocalteu reagent at 20−25°C in the presence of various salting-out agents. The azo coupling reactions of the studied phenols with 4-nitrophenyldiazonium, the redox reactions with 4-aminoantipyrine and the Folin–Ciocalteu reagent in an aqueous medium and in the presence of amphiphilic compounds based on nonionic (Triton X-110, OP-10, Triton X-114, Brij-35) and cationic (cetyltrimethylammonium chloride) surfactants are studied spectrophotometrically and colorimetrically. A comparative assessment of some metrological characteristics of the studied systems is given, the efficiency of the cloud point preconcentration methodology (CP extraction), which contributes to the reduction of the detection limits of phenols, is substantiated. Conditions for obtaining micellar-saturated phases of nonionic surfactants (their mixtures with cationic surfactants) in the absence and presence of reagents, analytes, salting-out agents (Na₂SO₄, NaCl, etc.), organic solvents (ethanol), and phase pH-inducing components (NaOH, Na₂CO₃) in polythermal and isothermal modes are optimized. Regularities facilitating the control of analytical effects in the studied systems are established: an increase in the volume of the micellar phase (<i>V</i>_m.p.) with an increase in <i>c</i>(surfactant) and <i>c</i>(C₂H₅OH), a decrease in the cloud point and <i>V</i>_m.p. depending on <i>c</i>(salting-out agent). Micellar-saturated phases of nonionic surfactants (their mixtures with cationic surfactants) are proposed as test solutions for effectively concentrating analytical forms of phenols (<i>R</i> = 85–97%) and determining them (individually and totally) at tenths and hundredths of the MAC in aqueous media and dosage forms at concentrations of <i>n</i> × 10⁻⁸ M using colorimetric methods using digital technologies.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"1007 - 1016"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148349742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Polychlorophenols in River Bottom Sediments Using Dynamic Online Preconcentration","authors":"A. S. Gubin,&nbsp;P. T. Sukhanov,&nbsp;A. A. Kushnir","doi":"10.1134/S1061934826700413","DOIUrl":"10.1134/S1061934826700413","url":null,"abstract":"<p>An online system for the dynamic preconcentration of chlorophenols from bottom sediments is proposed. It comprises a preconcentration column with a magnetic sorbent based on aminated hypercrosslinked polystyrene immobilized by two magnets, a container with the sample solution, a sorbent suspension, and rinse water. After preconcentration, the analytes are desorbed with acetonitrile, and the magnetic sorbent is rinsed in a regeneration column with hexane, methanol, and water. A peristaltic pump moves the analyte solution and magnetic sorbent through the system, and performs desorption with acetonitrile. Control of the peristaltic pumps, magnets for sorbent immobilization, and sorbent movement through the system is automatic. Dynamic sample preparation enables 1550- to 2070-fold concentration. To determine analytes by GC-MS, derivatization is performed using N,O-bis(trimethylsilyl)trifluoroacetamide. GC-MS combined with dynamic preconcentration enables the determination of 16 di-, tri-, tetrachlorophenols, and pentachlorophenol in bottom sediments at levels of 3–8 ng/kg. Analysis of real samples reveals that all 16 chlorophenols from the control mixture are present in bottom sediments near the discharge point of municipal wastewater treatment plants. Dichloroparabens are also identified in some samples at these same points. In areas with active agricultural activity, 2,4-dichlorophenol is the main pollutant. Elevated levels of tri- and tetrachlorophenols are found in bottom sediments in water bodies located in forest fire zones.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"942 - 955"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148349745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance Comparison of Conventional and On-Chip Electromembrane Extraction Techniques for the Quantification of Antidementia Drugs in Biological Samples Using High-Performance Liquid Chromatography","authors":"Nadiya Ekbatani Amlashi,&nbsp;Yadollah Yamini,&nbsp;Shayan Dadgarnejad,&nbsp;Mohammad Reza Hadjmohammadi","doi":"10.1134/S1061934825602762","DOIUrl":"10.1134/S1061934825602762","url":null,"abstract":"<p>This study presents a comparative evaluation of two sample preparation techniques—electromembrane extraction (<b>EME</b>) and on-chip electromembrane extraction (<b>CEME</b>)—combined with high-performance liquid chromatography for the sensitive and selective quantification of two antidementia drugs, rivastigmine and donepezil, in biological matrices. In the EME approach, analytes were extracted from bulk samples using hollow fiber-supported liquid membranes under an applied electric field, while in the CEME method, analytes were transferred across a solvent-impregnated membrane within a microfluidic chip under controlled flow and voltage conditions. Key operational parameters for both EME and CEME methods, including sample volume, extraction time, supported liquid membrane composition, pH, applied voltage, and flow or stirring rate, were systematically optimized using a one-variable-at-a-time approach. Under the optimized conditions, the performance of the techniques was evaluated in terms of linearity, sensitivity, and precision. The linear ranges for rivastigmine and donepezil were 1.0–8000 and 1.5–8000 μg/L, and 40.5–5000 and 50.8–5000 μg/L for EME and CEME, respectively. The results demonstrated that EME provided higher sensitivity and recovery, whereas CEME allowed effective extraction from small sample volumes with consistent reproducibility. The study highlights the advantages and limitations of each technique and suggests that both EME and CEME are suitable for routine pharmaceutical analysis of antidementia drugs in biological matrices. Overall, this work provides a comprehensive assessment of these two extraction methods, emphasizing their relevance, novelty, and potential applicability in clinical and pharmacokinetic studies.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"1036 - 1048"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148349712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smartphone Application-Based Rapid Antioxidant Evaluation of Musa paradisiaca Peel Extract with Gas Chromatography-Mass Spectrometry Chemical Profiling","authors":"Si Eon Lee,&nbsp;Moon-Moo Kim","doi":"10.1134/S1061934825603330","DOIUrl":"10.1134/S1061934825603330","url":null,"abstract":"<p>The increasing demand for rapid and cost-effective analytical methods has led to the development of smartphone-based applications for biochemical assays to assess antioxidant activity. In this study, the antioxidant activity of <i>Musa paradisiaca</i> peel ethyl acetate fraction (<b>MPPEF</b>) was evaluated using a conventional spectrophotometer and a smartphone application designed to quantify radical scavenging activity. Antioxidant capacity was assessed through reducing power and 2,2-diphenyl-1-picrylhydrazyl (<b>DPPH</b>) radical scavenging assays. For vitamin C, the reducing power assay showed a consistent concentration-dependent pattern between spectrophotometer and smartphone measurements, supporting the reliability of the mobile-based approach. In the DPPH radical scavenging assay, the mobile-based method also exhibited clear concentration-dependent behavior, further validating the method. Similarly, MPPEF exhibited clear dose-dependent antioxidant activity in both reducing power and DPPH radical assays, and the smartphone-based analysis showed comparable concentration-dependent trends to those obtained with the spectrophotometer. These findings suggest that smartphone-based colorimetric analysis not only demonstrates a consistent pattern with conventional spectrophotometry but also serves as a practical and portable alternative for antioxidant evaluation.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"1049 - 1057"},"PeriodicalIF":1.5,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148349744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}