Journal of Analytical Chemistry最新文献_第4页

A Green Approach to Ammonia Determination in Human Saliva Using Natural Reagent via Gas-Diffusion Flow-Injection Spectrophotometry 天然试剂气扩散流动注射法测定人唾液中氨的绿色方法

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701314

Hermin Sulistyarti, Lani Artana Putri, Vira Suryani, Rurini Retnowati, Ulfa Andayani, Ani Mulyasuryani, Erwin Sulistyo, Muhammad Mashuri Utama

{"title":"A Green Approach to Ammonia Determination in Human Saliva Using Natural Reagent via Gas-Diffusion Flow-Injection Spectrophotometry","authors":"Hermin Sulistyarti, Lani Artana Putri, Vira Suryani, Rurini Retnowati, Ulfa Andayani, Ani Mulyasuryani, Erwin Sulistyo, Muhammad Mashuri Utama","doi":"10.1134/S1061934824701314","DOIUrl":"10.1134/S1061934824701314","url":null,"abstract":"A simple and cost-effective analytical approach is proposed based on a gas diffusion-flow injection procedure for determining ammonia in human saliva. The proposed procedure utilizes purple sweet potato extract as an acceptor reagent. The principle of determining ammonia is based on the total ammonia in saliva, which is transformed to ammonia gas in the NaOH donor stream, which diffuses through the gas diffusion membrane to the acceptor stream containing purple sweet potato extract. The presence of ammonia changed the color of the extract, which was detected at a wavelength of 604 nm, with absorbance proportional to the ammonia concentration. Optimization of standard parameters produced optimal results under 1.5 M NaOH, 10% extract, and 50 cm mixing coil with 300 μL sample volume. The results of the procedure were selective against phosphate, magnesium, and calcium, with less than a 5% bias value. The result was valid when applied to human saliva and supported by a 101–103% recovery. The proposed gas diffusion-flow injection procedure offers on-site assay and green chemical analysis with relatively high throughput.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"79 12","pages":"1747 - 1756"},"PeriodicalIF":1.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Batch-Injection Amperometric Determination of Sulfamethazine, Sulfacetamide, and Sulfathiazole on an Electrode Modified with a Composite of Gold Nanoparticles, Carbon Nanotubes, and an Ionic Liquid 用金纳米颗粒、碳纳米管和离子液体复合材料修饰的电极批量注入安培计测定磺胺甲噁嗪、磺胺乙酰胺和磺胺噻唑

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701454

L. G. Shaidarova, I. A. Chelnokova, M. A. Il’ina, I. A. Gafiatova, H. C. Budnikov

{"title":"Batch-Injection Amperometric Determination of Sulfamethazine, Sulfacetamide, and Sulfathiazole on an Electrode Modified with a Composite of Gold Nanoparticles, Carbon Nanotubes, and an Ionic Liquid","authors":"L. G. Shaidarova, I. A. Chelnokova, M. A. Il’ina, I. A. Gafiatova, H. C. Budnikov","doi":"10.1134/S1061934824701454","DOIUrl":"10.1134/S1061934824701454","url":null,"abstract":"Electrodes modified with gold particles, multi-walled carbon nanotubes, an ionic liquid based on 1-butyl-3-methylimidazolium hexafluorophosphate, and a composite derived from these materials have been developed for the voltammetric determination of sulfamethazine, sulfacetamide, and sulfathiazole. Cyclic voltammetry reveals that modifying the surface of a glassy carbon electrode with gold particles, a composite of carbon nanotubes, and an ionic liquid increases its effective surface area. Electrochemical impedance data indicate that the rate of electron transfer on the modified electrodes surpasses that on the unmodified ones. The composite electrode containing gold particles, carbon nanotubes, and the ionic liquid, exhibited the best performance, was utilized for the amperometric determination of sulfonamides in a batch-injection analysis system. Optimal parameters for the determination of sulfonamides in the batch-injection setup were found. The relationship between the analytical signal and the concentration of the compounds on the logarithmic coordinates is linear, ranging from 1 × 10–8 to 5 × 10–3 M for sulfamethazine and sulfacetamide, and from 1 × 10–7 to 5 × 10–3 M for sulfathiazole. The proposed method for determining sulfonamides has been tested in ananalysis of pharmaceutical preparations.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"79 12","pages":"1878 - 1886"},"PeriodicalIF":1.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of Tianeptine Using Mg/Fe Layered Double Hydroxide-Based Dispersive Solid-Phase Extraction Combined with High-Performance Liquid Chromatography Mg/Fe层状双氢氧化物分散固相萃取-高效液相色谱法测定天奈汀

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701399

Weiwei Yang

{"title":"Determination of Tianeptine Using Mg/Fe Layered Double Hydroxide-Based Dispersive Solid-Phase Extraction Combined with High-Performance Liquid Chromatography","authors":"Weiwei Yang","doi":"10.1134/S1061934824701399","DOIUrl":"10.1134/S1061934824701399","url":null,"abstract":"The efficient extraction of tianeptine from environmental matrices has been a matter of concern issue due to the amphiphilic ionic organic substance property of tianeptine. A magnesium-iron layered double hydroxide (Mg/Fe-LDH) was successfully synthesized using hydrothermal synthesis and characterized by X-ray diffraction, Fourier transform infrared spectroscopy, and scanning electron microscopy techniques. The as-prepared nanocomposite was used as an effective adsorbent to extract tianeptine from water samples via a dispersive solid-phase extraction (DSPE) procedure before high-performance liquid chromatography-ultraviolet detection (HPLC-UV). Experimental parameters affecting extraction efficiency, such as agitation type, pH, absorbent amount, elution solvent type, and absorption/elution time, were studied and optimized. The developed tianeptine analysis method, based on adsorption-release extraction using Mg/Fe-LDH and detection by HPLC-UV, exhibited a wide quantitative linear range of 10 to 1000 μg/L (r2 = 0.9986, p = 2.49 × 10–14) by plotting chromatography peak height versus tianeptine concentration. The limits of detection and quantification were 4.6 and 15 μg/L, respectively. The developed tianeptine analysis method was applied to analyze tianeptine spiked in water samples. An ideal recovery range of 94.1 to 103.5%, with a narrow relative standard deviation of 1.63–4.34%, was obtained. The proposed analysis method, which combined Mg/Fe-LDH-based DSPE with HPLC-UV detection, was reliable for determining tianeptine in environmental water samples.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"79 12","pages":"1818 - 1825"},"PeriodicalIF":1.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pyridine-2,6-Dicarboxylic Acid Esters as Novel Ligands for Metal Extraction and Sensing 吡啶-2,6-二羧酸酯作为金属萃取和传感的新型配体

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701302

D. A. Kazanina, M. Yu. Alyapyshev, V. A. Polukeev, V. A. Babain, D. O. Kirsanov

{"title":"Pyridine-2,6-Dicarboxylic Acid Esters as Novel Ligands for Metal Extraction and Sensing","authors":"D. A. Kazanina, M. Yu. Alyapyshev, V. A. Polukeev, V. A. Babain, D. O. Kirsanov","doi":"10.1134/S1061934824701302","DOIUrl":"10.1134/S1061934824701302","url":null,"abstract":"N,O-hybrid donor ligands are promising compounds for the isolation and separation of actinides and lanthanides from process solutions of spent nuclear fuel reprocessing. Newly synthesized N,O-hybrid donor ligands – derivatives of 2,6-pyridinedicarboxylic acid were studied as extractants and membrane components for potentiometric sensors. The extraction ability of solutions of these compounds in meta-nitrobenzotrifluoride towards d- and f-elements from nitric and perchloric acid solutions was investigated. It was shown that the replacement of amide groups with ester groups reduces the extraction ability of the ligands. Switching from nitric acid to perchloric acid gives a dramatic increase in extraction capacity due to the perchlorate effect. Also, a significant increase in extraction capacity is observed when chlorinated cobalt dicarbolide is added to the organic phase: the highest distribution coefficient is observed at a 1 : 1 ratio of extractant and additive concentrations. Potentiometric membrane sensors based on the new ligands showed significant sensitivity to Cd2+. Correlations between extraction and sensing behavior of new ligands were studied.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"79 12","pages":"1733 - 1746"},"PeriodicalIF":1.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of X-ray Spectral Analysis in Russia to Determine Chemical Elements in Medicinal Plants 俄罗斯应用 X 射线光谱分析法测定药用植物中的化学元素

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701247

E. V. Chuparina, A. G. Revenko

引用次数: 0

A Simple and Sensitive Imidazolium-Based Ionic Liquid-Modified Reversed-Phase Liquid Chromatography Method for the Simultaneous Determination of Beta-Blockers in Human Plasma Samples 一种简单灵敏的基于咪唑离子液体的改良反相液相色谱法，用于同时测定人体血浆样品中的β-受体阻滞剂

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701387

Naflaa A. Aldawsari, Hassan M. AlBishri, Basmah H. Alshammari, Deia Abd El-Hady

{"title":"A Simple and Sensitive Imidazolium-Based Ionic Liquid-Modified Reversed-Phase Liquid Chromatography Method for the Simultaneous Determination of Beta-Blockers in Human Plasma Samples","authors":"Naflaa A. Aldawsari, Hassan M. AlBishri, Basmah H. Alshammari, Deia Abd El-Hady","doi":"10.1134/S1061934824701387","DOIUrl":"10.1134/S1061934824701387","url":null,"abstract":"Beta-blockers (β-blockers) are broadly used to manage cardiac arrhythmia, which could increase in the upcoming years due to the aging population and the increase in the number of patients with cardiac burden. In the current work, a simple, sensitive, and reliable simultaneous determination of five β-blockers (acebutolol, pindolol, atenolol, nadolol, and oxprenolol) was accomplished by ionic liquid (IL)-modified reversed-phase liquid chromatography with ultraviolet detection. The chromatographic separation was achieved on a ZORBAX® SB-C18 column using a hybrid mobile phase consisting of 50 µg/mL 1-butyl-3-methylimidazolium chloride dissolved in 0.02 mol/L phosphate buffer (pH 3.5) and acetonitrile (70 : 30, v/v). The chromatographic measurements were performed by isocratic elution at a 1.0 mL/min flow rate, 230 nm wavelength, and 25°C column temperature. The current method was applied to human plasma matrices by direct injection of samples with a short analysis time of 12 min. Good linearity was achieved in the range of 3–500 ng/L for atenolol, acebutolol, and pindolol, 7–500 ng/L for acebutolol, and 10–500 ng/L for oxprenolol with a 0.999 coefficient of determination. The limit of detection/limit of quantification values were 1.04/3.00, 2.75/7.00, 1.03/3.00, 1.05/3.00, and 3.47/10.00 ng/L for atenolol, nadolol, acebutolol, pindolol, and oxprenolol, respectively. Results of intra-day and inter-day precision were found to be less than 2%. The sensitivity enhancement factors of analytes due to the addition of IL ranged between 9- and 41-fold higher than that achieved in the absence of IL. Therefore, the proposed method could be used as a simple and sensitive analytical method for routine clinical analysis of β-blockers with the presence of a small amount of IL.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"79 12","pages":"1808 - 1817"},"PeriodicalIF":1.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stability-Indicating High-Performance Thin-Layer Chromatography Method Development and Validation for Topiroxostat in Bulk and Tablet Dosage Forms Using a Quality by Design Approach 采用 "质量源于设计 "方法，开发和验证散剂和片剂中托吡罗司他的稳定指示型高效薄层色谱法

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701442

Shubhangee S. Gaikwad, Pratik V. Dhakne, Amol S. Bansode, Amruta A. Bankar

{"title":"Stability-Indicating High-Performance Thin-Layer Chromatography Method Development and Validation for Topiroxostat in Bulk and Tablet Dosage Forms Using a Quality by Design Approach","authors":"Shubhangee S. Gaikwad, Pratik V. Dhakne, Amol S. Bansode, Amruta A. Bankar","doi":"10.1134/S1061934824701442","DOIUrl":"10.1134/S1061934824701442","url":null,"abstract":"A new, simple, rapid, accurate, and precise high-performance thin-layer chromatography (HPTLC) method has been developed for the estimation of topiroxostat in bulk and tablet dosage form. In this method, aluminum plates with precoated silica gel 60 F254 were used as the stationary phase. The mobile phase consisted of ethyl acetate, toluene, methanol, and glacial acetic acid (5 : 4 : 1 : 0.1, v/v/v). The calibration plot showed good linearity in the range of 40–240 ng/spot with a coefficient of regression, r2 of 0.994, with respect to peak area. Ishikawa (fishbone) diagram and failure mode effect analysis were used as risk assessment tools. The saturation time, band length, and volume of methanol were determined as critical method parameters and extensively optimized employing Box-Behnken design, with a focus on the retardation factor value as the critical analytical attribute. The method was validated according to the International Conference on Harmonization guideline Q2 (R1). The limits of detection and quantitation were 1.45 and 4.41, respectively. The percentage recovery was found to be 99.59%. The degradation study was carried out in acidic, basic, oxidative, neutral, dry heat, and photolytic conditions. Therefore, it was concluded that the developed HPTLC method can be applied for the identification and quantitative determination of topiroxostat in bulk and tablet dosage form.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"79 12","pages":"1865 - 1877"},"PeriodicalIF":1.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Rapid, Validated High-Performance Liquid Chromatography Method for Simultaneous Quantitation of Phytoconstituents in Asteracantha longifolia (L.) Nees Using a Quality by Design Approach 采用 "质量源于设计 "的方法，建立快速、有效的高效液相色谱法，用于同时定量检测 Asteracantha longifolia (L.) Nees 中的植物成分

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701429

Sadanand E. Raval, Seema R. Sapale, Vikas V. Vaidya

{"title":"A Rapid, Validated High-Performance Liquid Chromatography Method for Simultaneous Quantitation of Phytoconstituents in Asteracantha longifolia (L.) Nees Using a Quality by Design Approach","authors":"Sadanand E. Raval, Seema R. Sapale, Vikas V. Vaidya","doi":"10.1134/S1061934824701429","DOIUrl":"10.1134/S1061934824701429","url":null,"abstract":"Asteracantha longifolia (L.) Nees, a small, spiny weed, has effective antitumor, hypoglycemic, aphrodisiac, antibacterial, free radical scavenging, lipid peroxidation, and hepatoprotective properties. It is an essential herb in many traditional and herbal medicines. Active phytoconstituents such as betulin, lupeol, stigmasterol, and β-sitosterol are reported to accord the herb importance as a medicinal plant in modern and traditional medicine. With the implementation of recent regulatory requirements, monitoring raw materials' quality attributes and quantifying the essential phytoconstituents is crucial. Therefore, this article discusses the first-time application of the quality by design (QbD) approach for Asteracantha longifolia (L.) Nees in developing a sensitive, rapid analytical method for the simultaneous quantitation of four bioactive phytoconstituents using high-performance liquid chromatography equipped with photodiode array detector, and validated fully in line with the guidelines by ICH. The QbD approach is an application of risk assessment and determines a design space where the developed analytical method performs at its best compared to traditional methods.","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"79 12","pages":"1844 - 1855"},"PeriodicalIF":1.0,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142821400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nondestructive Control of Macrolides in Tableted Pharmaceuticals Using Near-IR Fourier-Transform Spectrometry and Digital Colorimetry 利用近红外傅立叶变换光谱法和数字比色法对片剂药品中的大环内酯类药物进行无损检测

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S106193482470134X

V. G. Amelin, O. E. Emel’yanov

引用次数: 0

Development and Validation of a Simple, Precise, and Robust Reversed-Phase High-Performance Liquid Chromatography-Ultraviolet Method for the Determination of Polyvinylpyrrolidone in Adhesives 一种简单、精确、稳健的反相高效液相色谱-紫外法测定胶粘剂中聚乙烯吡咯烷酮的建立与验证

IF 1 4区化学

Journal of Analytical Chemistry Pub Date : 2024-12-14 DOI: 10.1134/S1061934824701417

Anand Gupta, Kanchan Nautiyal, Anubhav Saxena

引用次数: 0