中国地球物理学会年刊最新文献_第9页

3D registration of medical scanner volumes and tissue section photographs for evaluation of image-guided treatment 用于评价图像引导治疗的医学扫描仪体积和组织切片照片的三维配准

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1106249

R. Lazebnik, D. Wilson, M. Breen, J. Lewin

引用次数: 0

Filtering of surface Laplacian electrocardiograms from humans to produce atrial activation patterns 过滤人体表面拉普拉斯心电图以产生心房激活模式

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1106439

W. Besio, P. Tarjan

引用次数: 5

Examining bifurcations in resistance of collapsible blood vessels 可折叠血管阻力分岔的研究

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1106409

T. Barton-Scott, G. Drzewiecki

引用次数: 0

Using direct force measurements to determine the mechanism of neural cell adhesion molecule (NCAM) function 利用直接力测量确定神经细胞粘附分子(NCAM)功能的机制

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1134524

D. Leckband, C. Johnson, R. A. Roberts, I. Fujimoto, B. Anderson, U. Rutishauser

引用次数: 0

Electrophysiological neuroimaging of brain activity 脑活动的电生理神经成像

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1053120

B. He, J. Lian

引用次数: 4

Learning medical imaging in classroom, virtual classroom and laboratory classroom 在课堂、虚拟课堂和实验室课堂学习医学影像

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1053457

Weizhao Zhao, Chunyan Wu, Xiaodong Wu, R. Prado, P. Pattany

引用次数: 2

Thermal facial screening for deception detection 用于欺骗检测的热面部筛选

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1106317

I. Pavlidis, J. Levine

引用次数: 25

The affect of relative lordosis on dynamic torsional stability in the lumbar spine 相对前凸对腰椎动态扭转稳定性的影响

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1053416

R. P. Morris, K. Garges, R. Patterson, J. Yang, W. Buford, A. Muffoletto, J. Simmons

{"title":"The affect of relative lordosis on dynamic torsional stability in the lumbar spine","authors":"R. P. Morris, K. Garges, R. Patterson, J. Yang, W. Buford, A. Muffoletto, J. Simmons","doi":"10.1109/IEMBS.2002.1053416","DOIUrl":"https://doi.org/10.1109/IEMBS.2002.1053416","url":null,"abstract":"The purpose of the study is to investigate one of the factors that appear to be responsible for the high incidence of back pain and disability, inefficacious lumbar lordosis. It has been the observation of many back pain specialists that patients with back pain and disc problems have a decreased lumbar curvature; this has been presumed by some to be a result of muscle spasm, but by others as a cause of the primary malady. Six cadaver spinal segments were tested on a materials testing system (MTS) in varying degrees of lumbar curvature to see whether the curvature had an affect on stability with compression and rotation, the motions responsible for many back injuries. In all cases, increased lumbar lordosis correlated with increased stiffness, This correlation was at a maximum with respect to the spines tested, in the one with the least amount of osteopenia (estimated by radiographs and age of specimens). The results suggest that lumbar lordosis correlates with increased stiffness in cadaveric specimens. This study is ongoing and preliminary results suggest a larger sample size for the mechanical testing is needed for the study to be conclusive and statistically valid. Once that is achieved, the correlations and clinical significance can be determined.","PeriodicalId":60385,"journal":{"name":"中国地球物理学会年刊","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83918407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regulation of cardiac repolarization by adenoviral gene transfer rationalized by computational modeling 计算模型证明了腺病毒基因转移对心脏复极化的调节作用

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1053257

R. Mazhari, E. Marbán, R. Winslow

{"title":"Regulation of cardiac repolarization by adenoviral gene transfer rationalized by computational modeling","authors":"R. Mazhari, E. Marbán, R. Winslow","doi":"10.1109/IEMBS.2002.1053257","DOIUrl":"https://doi.org/10.1109/IEMBS.2002.1053257","url":null,"abstract":"Regulatory subunit KCNE3 (E3) interacts with KCNQ1 (Q1) in epithelia, regulating its activation kinetics and augmenting current density. Since E3 is expressed weakly in the heart, we hypothesized that ectopic expression of E3 in cardiac myocytes might abbreviate action potential duration by interacting with Q1 and augmenting the delayed rectifier current (I/sub K/). We constructed an adenoviral vector co-expressing GFP and E3, and injected it Into the left ventricular cavity of guinea pigs. After 72 hrs, the electrocardiographic QT interval was reduced by /spl sim/10% compared to baseline. E3-transduced cells had an APD/sub 90/ of 87 /spl plusmn/ 8 vs. 298 /spl plusmn/ 19 ms in control cells, while E-4031-insensitive I/sub K/ and activation kinetics were significantly augmented. Quantitative modeling of a transmural cardiac segment rationalized the degree of QT-interval abbreviation as a consequence of electrotonic interactions in the face of limited transduction efficiency and showed that heterogeneous transduction of E3 may actually potentiate arrhythmias. The results provide proof of the principle that ectopic expression of regulatory subunits can be exploited to enhance repolarization, a principle that may be useful in treating long QT syndrome (but only if fairly homogeneous ventricular expression can be achieved).","PeriodicalId":60385,"journal":{"name":"中国地球物理学会年刊","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2002-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74596009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New degradable cationic polyesters for nonviral gene delivery 用于非病毒基因传递的新型可降解阳离子聚酯

中国地球物理学会年刊 Pub Date : 2002-12-01 DOI: 10.1109/IEMBS.2002.1136945

Jie Fu, E. Krauland, Y. Har-el, J. Hanes

引用次数: 0