ACS Applied Materials & Interfaces最新文献_第5页

IF 8.3 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02

Syamini Jayadevan, Akshaya Kumar Aliyana and George K. Stylios*,

引用次数: 0

IF 8.3 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02

Mone’t Sawyer, Amevi Semodji, Olivia Nielson, Attila Rektor, Hailey Burgoyne, Michael Eppel, Josh Eixenberger, Raquel Montenegro-Brown, Miranda L. Nelson, Trevor J. Lujan and David Estrada*,

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IF 8.3 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02

Qingda Du, Yinglong Zhang, Jiajing Tang, Wei Fang, Xiaoyu Lei, Jinzheng Zhang, Bo Mu, Yuping Li, Yi Zuo* and Yubao Li*,

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IF 8.3 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02

Jinwook Lee, Geun Park, Gyeong Chan Kim, Jung-Hoon Yun and Jooyoun Kim*,

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IF 8.3 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02

Haoqin Ma, Ge Wang, Xinghua Sheng, Dongchen Tan, Qinglei Guo, Nan Sun, Sheng Bi*, Shuai Yang, Jijie Huang and Chengming Jiang*,

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A Biomimetic Janus Fibrous Membrane for Scarless Achilles Tendon Regeneration via Synergistic Modulation of an Oxidative-Inflammatory Cascade. 通过氧化-炎症级联的协同调节，用于无瘢痕跟腱再生的仿生Janus纤维膜。

IF 9.5 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02 DOI: 10.1021/acsami.5c05336

Zijian Li,Hufei Wang,Xiao Liu,Zhengyang Chang,Jianpeng Gao,Junyao Cheng,Licheng Zhang,Xing Wang,Ming Li,Jianheng Liu,Peifu Tang

{"title":"A Biomimetic Janus Fibrous Membrane for Scarless Achilles Tendon Regeneration via Synergistic Modulation of an Oxidative-Inflammatory Cascade.","authors":"Zijian Li,Hufei Wang,Xiao Liu,Zhengyang Chang,Jianpeng Gao,Junyao Cheng,Licheng Zhang,Xing Wang,Ming Li,Jianheng Liu,Peifu Tang","doi":"10.1021/acsami.5c05336","DOIUrl":"https://doi.org/10.1021/acsami.5c05336","url":null,"abstract":"Achilles tendon injuries present significant clinical challenges due to limited regenerative capacity and frequent adhesion formation. Here, we report a melatonin-loaded Janus fibrous membrane (MLT@JFM) that mimics the native paratenon's structure and function to promote scarless tendon healing. The biomimetic membrane consists of an inner methacrylated silk fibroin (SFMA) layer that promotes tendon stem cell functions and an outer melatonin-loaded polycaprolactone methacryloyl (PCLMA) layer that prevents adhesion formation. Through photo-cross-linking and structural interlocking, MLT@JFM achieves excellent mechanical properties and stable fixation around injured tendons. In vitro studies demonstrate that MLT@JFM effectively scavenges reactive oxygen species, modulates macrophage polarization, and maintains tendon stem cell phenotype under inflammatory conditions. In a rat Achilles tendon injury model, MLT@JFM significantly enhances functional recovery and biomechanical properties while preventing adhesion formation. Transcriptomic analysis reveals that MLT@JFM promotes scarless healing through synergistic regulation of oxidative-inflammatory cascades and the enhancement of tissue regeneration. This study presents MLT@JFM as a promising therapeutic strategy for tendon repair and provides new insights into biomaterial-mediated tissue regeneration.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"2 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144533588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inorganic Nanomaterials for Osteoarthritis: From Delivery Vehicles to Therapeutic Agents. 无机纳米材料治疗骨关节炎：从运载工具到治疗剂。

IF 9.5 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02 DOI: 10.1021/acsami.5c07562

Xinyu Zhang,Mingda Zhao,Xiaolin Xiao,Yaping Zou,Jiadong Li,Hailong Wang,Gongbing Liu,Xiang Ren,Chunyu Tan,Yujiang Fan,Yong Sun

{"title":"Inorganic Nanomaterials for Osteoarthritis: From Delivery Vehicles to Therapeutic Agents.","authors":"Xinyu Zhang,Mingda Zhao,Xiaolin Xiao,Yaping Zou,Jiadong Li,Hailong Wang,Gongbing Liu,Xiang Ren,Chunyu Tan,Yujiang Fan,Yong Sun","doi":"10.1021/acsami.5c07562","DOIUrl":"https://doi.org/10.1021/acsami.5c07562","url":null,"abstract":"Osteoarthritis (OA) is a common heterogeneous disorder affecting the whole joint. It presents significant challenges in current treatment, which remains based on symptomatic management rather than mechanistically alleviating OA. Inorganic nanomaterials have emerged as a significant research field in modern materials science due to their unique physicochemical properties and wide range of potential applications. This review focuses on the transformation of the role of inorganic nanomaterials from delivery tools to therapeutic agents in the treatment of OA. It examines various nanomaterials, including carbon-based, silicon-based, and transition metal-based, that deliver drugs to alleviate swelling, inflammation, and pain in the joint. It also highlights inorganic nanomaterials that function autonomously through lubrication, photothermal therapy, electrical stimulation therapy, superparamagnetic properties, and enzyme-like activities. Overall, this review encapsulates the evolution of inorganic nanomaterials in the treatment of OA, from serving solely as delivery vehicles to becoming therapeutic agents, forecasting a future where they evolve toward autonomous functioning and integrated therapeutics for OA.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"46 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogen Isotope (1H/2H/3H) Separation in Solution Using Graphene Transferred on PTFE-Reinforced Nafion. 聚四氟乙烯增强Nafion上转移石墨烯分离溶液中氢同位素（1H/2H/3H）。

IF 9.5 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02 DOI: 10.1021/acsami.5c08414

Hyojoo Kim,Hongdoo Kim,Bhupendra Kumar Singh,Jonghoon Park,Juhwan Ahn,Hyung Gyu Park,Wooyong Um

{"title":"Hydrogen Isotope (1H/2H/3H) Separation in Solution Using Graphene Transferred on PTFE-Reinforced Nafion.","authors":"Hyojoo Kim,Hongdoo Kim,Bhupendra Kumar Singh,Jonghoon Park,Juhwan Ahn,Hyung Gyu Park,Wooyong Um","doi":"10.1021/acsami.5c08414","DOIUrl":"https://doi.org/10.1021/acsami.5c08414","url":null,"abstract":"The separation and enrichment of tritium from radioactive wastewater remain critical challenges in the nuclear power and fusion industries. While hydrogen isotope separation from H2/D2 gas mixtures has been demonstrated using electrochemical pumping systems with Nafion|graphene composite membranes, their application in liquid water remains limited, despite tritium and deuterium predominantly existing as water molecules. This limitation primarily arises from the swelling behavior of Nafion, which absorbs water and induces defects in the graphene layer. In this study, we propose a modified Nafion|graphene composite membrane structure, where graphene is transferred onto polytetrafluoroethylene-reinforced Nafion, to enable efficient hydrogen isotope (1H, 2H, and 3H) separation in liquid water. The monolayer graphene exhibited six-fold higher conductivity for H+ over D+ under electrically driven conditions, while diffusion-driven transport showed lower isotope selectivity due to the contribution of the vehicular mechanism. Notably, graphene imposed a 1.7-fold higher diffusion energy barrier for tritium than for deuterium, indicating that the separation is governed by zero-point energy differences in O-H(D, T)···O bonding. These results highlight the role of transport mechanism and graphene integrity in isotope separation performance and suggest a practical pathway toward implementing graphene-based membranes in polymer electrolyte membrane water electrolysis systems for tritium concentration and removal.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"5 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NIR-II Luminescent Nanothermometer for Precise Assessment of Ischemic Stroke. NIR-II型荧光纳米体温计用于缺血性脑卒中的精确评估。

IF 9.5 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02 DOI: 10.1021/acsami.5c05030

Xiaochen Qiu,Wei Yuan,Chen Jiang,Wei Feng,Fuyou Li

{"title":"NIR-II Luminescent Nanothermometer for Precise Assessment of Ischemic Stroke.","authors":"Xiaochen Qiu,Wei Yuan,Chen Jiang,Wei Feng,Fuyou Li","doi":"10.1021/acsami.5c05030","DOIUrl":"https://doi.org/10.1021/acsami.5c05030","url":null,"abstract":"Ischemic stroke, an acute cerebral local blood circulation disorder caused by neurological deficit syndrome, has emerged as a prominent ailment that can affect the well-being and quality of life of the elderly. The difficulty in early assessment and narrow therapeutic time window can increase the risks of mortality and disability. Monitoring the temperature of brain microregions is a promising strategy for assessing the onset of an early stroke, which is positively correlated with the intricate immune response. In this study, an innovative hybrid nanothermometer combining lanthanides and quantum dots was established for contactless monitoring of cerebral lesion temperatures in mice with ischemic stroke. The output of ratio optical signals in the near-infrared-II window (1000-1700 nm) guaranteed deep penetration, high accuracy, and reduced tissue damage. An obvious temperature increase was detected in the minor middle cerebral artery occlusion model mice (4 h after reperfusion), indicating the occurrence of a minor stroke even in the absence of abnormal behaviors. Moreover, a further increase in the brain temperature of the ischemic region resulted in a more severe cerebral lesion, suggesting the potential advancement of the treatment window for early ischemic stroke. The proposed approach can enable precise assessment of ischemic stroke, with significant implications for the incidence and progression of the illness, ultimately enhancing the quality of life of affected patients.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"40 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 8.3 2区材料科学

ACS Applied Materials & Interfaces Pub Date : 2025-07-02

Baochen Cui*, Min Cao, Jinwei Weng, Yutong Li, Chen Wang, Junchao Liu, Yihao Wen, Leiming Tao* and Shuzhi Liu*,

引用次数: 0