ACS Applied Materials & Interfaces最新文献

{"title":"Cascade-Catalytic MnO2 Nanoreactor Amplifies Oxidative Stress and Activates cGAS–STING Pathway To Remodel the Immunosuppressive Microenvironment of Triple-Negative Breast Cancer","authors":"Shiman Li,Shuchang Yao,Jingwen Yang,Wenqi Wang,Wenjing Li,Xinzhu Wang,Ke Zhang,Sha Xie,Xiaoyu Peng,Jian Ni,Xiaoxv Dong","doi":"10.1021/acsami.6c15680","DOIUrl":"https://doi.org/10.1021/acsami.6c15680","url":null,"abstract":"Triple-negative breast cancer (TNBC) is characterized by a highly immunosuppressive tumor microenvironment, which severely limits the therapeutic efficacy of current immunotherapies. To address this challenge, we developed a hyaluronic acid-modified tumor-targeted MnO2 nanoreactor (HMGR@HA) for the codelivery of GOx and 20(S)-ginsenoside Rg3 (Rg3), thereby integrating metabolic interference with cascade catalytic therapy and endogenous immune activation. In this system, GOx continuously catalyzed the oxidation of glucose to generate H2O2, which was subsequently converted by MnO2 into highly cytotoxic reactive oxygen species (ROS) while simultaneously producing oxygen. This process established a self-reinforcing catalytic cycle that effectively circumvented the intrinsic limitation of insufficient endogenous H2O2 within the tumor microenvironment. The resulting amplified oxidative stress, in synergy with the chemotherapeutic effect of Rg3, induced profound mitochondrial dysfunction and triggered the cytosolic release of mtDNA. As a potent endogenous danger signal, cytosolic mtDNA robustly activated the cGAS-STING signaling axis, thereby converting localized oxidative damage into strong innate immune activation. In addition, HMGR@HA induced immunogenic cell death (ICD), promoted dendritic cells (DCs) maturation, enhanced infiltration of CD4+ and CD8+ effector T cells, and significantly depleted regulatory T cells (Tregs), collectively leading to extensive remodeling of the tumor immune microenvironment. Ultimately, this self-amplifying catalytic platform effectively drives the transition from localized tumor eradication to systemic antitumor immunity, offering a highly efficient therapeutic strategy for TNBC immunotherapy.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"7 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invisible Patterned Silver-Based Transparent Electrodes via Control of Light Scattering and Absorption","authors":"Aleksandra Pająk,Pavel Pleskunov,Oleg Zabeida,Bill Baloukas,Jolanta Klemberg-Sapieha,Ludvik Martinu","doi":"10.1021/acsami.6c09340","DOIUrl":"https://doi.org/10.1021/acsami.6c09340","url":null,"abstract":"The demand for transparent flexible electrodes (TFEs) with superior simultaneous optical, electrical, and mechanical performance beyond indium tin oxide (ITO) has driven the development of various nanostructured architectures. Metal-based patterned surfaces have become strong contenders in the TFEs field due to their significantly higher mechanical flexibility; however, their current use is, in part, limited by their scattering-induced visibility to the naked eye. Herein, we report polymeric web-assisted two-dimensional nanostructures, fabricated via electrospinning and integrated with gas-phase deposition methods such as magnetron sputtering, yielding thin film nanopatterning with ultra-high luminous transmittance (Tlum) of 98.1% and sheet resistance (Rs) of 17 Ω □–1. The addition of an antireflective coating enhances the Tlum to 99.7%. The designed trilayer, highly absorbing Fabry–Perot stack (Ag/ITO/NiCr) sputtered on patterned nanolines (NLs) leads to backward scattering suppression, rendering them significantly less visible than the “uncloaked” Ag-only NLs. Our findings are confirmed by finite-difference time-domain (FDTD) simulations. These high-performing, near-invisible electrodes allow for adjustable conductivity through thickness control without compromising transparency, while maintaining mechanical robustness under bending. They are also compatible with polymeric substrates, requiring only room-temperature polymer template dissolution, eliminating the need for high-temperature annealing and representing a promising route toward next-generation optoelectronic applications, including displays, photovoltaics, and wearable electronics.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"1 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermal Transport in Atomic Layer Deposition-Grown Beryllium Oxide Thin Films and Implications on Device Cooling","authors":"Husam Walwil,Jonghyun Bae,Seokjun Kim,Dohwan Jung,Nipun Sutradhar,Asad Ali,Sadikul Alam,Robert M. Lavelle,Mohamadali Malakoutian,Kelly Woo,Kaiyan Shan,Hongkun Li,Weidong Zheng,Prakash R. Sultane,Christopher W. Bielawski,Minji Kim,Jiun Oh,Joon Seop Kwak,Srabanti Chowdhury,Jinwoo Hwang,Jae-Hyun Ryou,Jungwoo Oh,Sukwon Choi","doi":"10.1021/acsami.6c16056","DOIUrl":"https://doi.org/10.1021/acsami.6c16056","url":null,"abstract":"Thin film beryllium oxide (BeO) is an emerging material that can potentially be used as a high thermal conductivity gate dielectric and/or passivation layer for high power electronic devices. This study presents the measurement of the thermal conductivity and thermal boundary conductance associated with plasma-enhanced atomic layer deposition (PEALD)-grown polycrystalline BeO films on Si substrates with thicknesses ranging from 25 to 250 nm. The measured out-of-plane thermal conductivities of the 250, 113, 53, and 26 nm-thick BeO films are 13.45 ± 1.45, 8.7 ± 1.35, 7.2 ± 2.1, and 5 ± 2.2 W m–1 K–1, respectively, representing an order-of-magnitude improvement over conventional dielectric materials such as SiN and SiO2. The measured thermal boundary conductance across the BeO/Si interface is ∼200 MW m–2 K–1 at room temperature, which approaches the intrinsic interface limit and suggests that interfacial heat transport is predominantly governed by elastic phonon transmission. The growth of a ∼200 nm-thick polycrystalline diamond film on an AlGaN/GaN-on-Si epitaxial wafer using a 5 nm-thick BeO diamond-seeding is demonstrated, where the structural integrity of the underlying AlGaN/GaN heterostructure is fully preserved. Thermal simulations of AlGaN/GaN high electron mobility transistors (HEMTs) integrated with a top-side polycrystalline diamond heat spreader predict that replacing the conventional SiO2 passivation and nucleation layers with BeO helps reduce the channel temperature rise by an additional 5.2%.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"63 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interfacial Regulation via Organic-Inorganic Interpenetrating Networks for Enhanced Protection in Waterborne Polyurethane Nanocomposites","authors":"Shen Wang,Maocheng Ji,Yongqi Zhang,Xinzhong Song,Jianyong Li,Jianfeng Li,Jia Man","doi":"10.1021/acsami.6c17358","DOIUrl":"https://doi.org/10.1021/acsami.6c17358","url":null,"abstract":"The abundance of hydrophilic groups and the linear polymer chain structure in waterborne polyurethane (WPU) lead to insufficient water resistance and corrosion protection. These inherent characteristics make it challenging for WPU to be applied in the marine protection field, where high comprehensive performance of coatings is demanded. Herein, a WPU nanocomposite was designed incorporating hydroxyl-terminated polydimethylsiloxane and bifunctionalized nano-silica (modified with 3-aminopropyltriethoxysilane and propyltrimethoxysilane) during prepolymerization. This strategy established an organic–inorganic interpenetrating cross-linked network through covalent bonding and intermolecular interactions. The silica nanoparticles act as interfacial bridges between polymer segments, mitigating phase separation and agglomeration caused by polarity mismatch, thereby enhancing coating compactness and improving stress transfer. Performance tests demonstrate that the properties of the coating have been comprehensively enhanced. The coating exhibits an elongation at break of 254.64% while maintaining a tensile strength of 21.17 MPa. Additionally, the water absorption rate of the coating decreases to approximately 5%, the electrochemical protection efficiency reaches 99.9920%, and no obvious corrosion phenomenon is observed after a 7 day salt spray corrosion test. Additionally, the coating shows excellent drag-reduction performance, with a drag-reduction rate of 6.56% under turbulent flow. By integrating interfacial design with nanocomposite architecture, this work develops a robust WPU coating system suitable for marine engineering applications, and employs molecular dynamics simulations to reveal the microscopic mechanism by which amino and n-propyl silane dual modification inhibits the aggregation of silica nanoparticles as well as the interfacial interaction mechanism, thereby highlighting the role of colloidal and nanomaterial strategies in advancing functional protective coatings.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"14 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Situ Tracking of Se Vacancy-Promoted Surface Reconstruction of NiCoSe2 into NiCoOOH during Alkaline Oxygen Evolution","authors":"Suprobhat Singha Roy,Abhishek Muraleedharan,Vishesh Vishesh,Vidyoth Koka Ruparani,Fajar Dhanish C P,Subrata Kundu","doi":"10.1021/acsami.6c15313","DOIUrl":"https://doi.org/10.1021/acsami.6c15313","url":null,"abstract":"Understanding the dynamic surface reconstruction of precatalyst materials during the oxygen evolution reaction (OER) is a forefront area of research for designing and studying effective electrocatalysts. Here, we report the deliberate engineering of Se vacancies in NiCoSe2 via a facile NaBH4 reduction strategy and systematically investigate how anion vacancies govern surface reconstruction behavior under alkaline OER conditions. The presence of Se vacancies is confirmed via EPR spectroscopy and ICP-MS analysis. Cyclic voltammetry and in situ electrochemical impedance spectroscopy during the electrochemical activation process reveal that the vacancy-enriched NiCoSe2–x undergoes faster and more extensive structural reconstruction than pristine NiCoSe2. Quasi in situ ATR-FTIR and Raman spectroscopy track the dynamic evolution of NiCoOOH during anodic polarization, providing direct spectroscopic evidence for the Se vacancy-promoted NiCoOOH active phase generation with abundant Ni–O–Co synergy. Evaluation of electrochemical surface area and turnover frequency establishes that the generation of abundant Ni–O–Co synergy in NiCoSe2–x simultaneously increases the density of accessible active sites and enhances the intrinsic activity per site. Consequently, the NiCoSe2–x precatalyst delivers significantly improved OER performance relative to bare NiCoSe2, along with high Faradaic selectivity and long-term stability. Post-stability characterizations confirm bulk structural and morphological reconstruction driven by Se vacancies and thus highlight the complete utilization of the available catalytic sites. This work provides a fundamental mechanistic framework linking anion vacancy engineering, surface reconstruction kinetics/mechanism tracking, and intrinsic OER activity enhancement in bimetallic chalcogenide precatalysts, offering rationalized design principles for next-generation earth-abundant OER catalysts.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"73 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ROS-Responsive Hydrogel for Spatiotemporal Cascade Regulation of Ferroptosis and Fibrosis for Myocardial Protection","authors":"Shaodong Zhai,Zhenghao Wang,Jing Wang,Xiang Guo,Xiao Tan,Hongnv Zhang,Ruiping Zhang,Nan Hu","doi":"10.1021/acsami.6c15728","DOIUrl":"https://doi.org/10.1021/acsami.6c15728","url":null,"abstract":"Myocardial infarction (MI)-induced cardiac injury is mainly divided into two phases: the acute necrotic phase and the repair phase. Given the distinct therapeutic requirements of each phase—salvaging dying cardiomyocytes and reducing infarct size in the acute phase, while achieving controlled fibrosis to promote effective ventricular remodeling in the repair phase—we designed an ROS-responsive hydrogel co-delivery system (Met/Anti-34a@Gel) loaded with metformin (Met) and Anti-34a liposomes (Anti-34a Lip) to achieve precise regulation of both the acute and repair phases of MI. In the highly oxidative stress microenvironment following MI, the hydrogel gradually degrades and releases Met and Anti-34a Lip in a stage-specific manner. Met improves mitochondrial function, inhibits oxidative stress and ferroptosis, thereby effectively salvaging cardiomyocytes in the acute phase. Anti-34a Lip modulates the differentiation behavior of cardiac fibroblasts, suppressing excessive fibrosis and promoting favorable ventricular remodeling in the repair phase. Echocardiography revealed that Met/Anti-34a@Gel preserved left ventricular ejection fraction (EF) and fractional shortening (FS) at 72 h post-MI, reduced serum MDA levels in the acute phase, and maintained EF at approximately 60.92 ± 8.37% with a lower collagen I/III ratio at 4 weeks, collectively demonstrating both acute cardioprotection and long-term anti-fibrotic remodeling. In this combined therapeutic strategy, the early mitochondrial protection and anti-ferroptosis effects establish a favorable tissue and functional foundation for subsequent precision anti-fibrotic therapy, while the later anti-fibrotic treatment further consolidates the early protective effects. The two actions synergistically form a positive feedback loop, ultimately achieving sustained long-term cardiac functional improvement.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"12 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanoscale Surface Modification of Li6PS5Cl Particles To Stabilize Lithium Solid-State Battery Interfaces","authors":"Bing-Xuan Shi,Timo Weintraut,Thomas Demuth,Sabrina Sicolo,Boburmirzo Juraev,Sebastian L. Benz,Burak Aktekin,Kilian Vettori,Yuriy Yusim,Karsten Albe,Kerstin Volz,Anja Henss,Felix H. Richter","doi":"10.1021/acsami.6c13206","DOIUrl":"https://doi.org/10.1021/acsami.6c13206","url":null,"abstract":"Thiophosphate solid electrolytes (SEs) may enable the energy storage transformation to solid-state batteries, but interface instability and lithium dendrite formation significantly limit their practical application. To address these challenges, we present a scalable N-methyl-2-pyrrolidone (NMP) surface modification to boost the performance of Li6PS5Cl (LPSCl) SE. This NMP surface modification on LPSCl improves electrochemical stability of the SE in the positive electrode and stabilizes the lithium-metal interface when used as a separator. When used as SE in positive electrode and separator, the modified LPSCl (m-LPSCl) increases the first cycle discharge capacity by ∼11 mAh g–1 at a current density of 0.21 mA cm–2 and improves capacity retention by 10% over pristine LPSCl (p-LPSCl) after 100 cycles. As a separator, higher critical current density is reached with m-LPSCl (1.6 mA cm–2) than with p-LPSCl (1 mA cm–2) before shorting of the cell. For the pair of single-crystal LiNiO2 (LNO)-positive electrode and lithium metal-negative electrode, m-LPSCl enables over 100 stable cycles, significantly outperforming the cell with p-LPSCl, which shorts after 25 cycles. Overall, this study introduces a scalable method for modifying LPSCl by solvent treatment that improves positive electrode performance and increases stability of the lithium metal-negative electrode interface.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"14 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication of Microwave-Responsive Confined NaCl in Polydopamine","authors":"Guxia Wang,Yingdong Wei,Mimi Xu,Dan Li,Shengwei Guo","doi":"10.1021/acsami.6c14835","DOIUrl":"https://doi.org/10.1021/acsami.6c14835","url":null,"abstract":"Microwave-responsive nanoparticles hold promising applications in microwave thermal therapy and electromagnetic shielding; however, fabricating nanoparticles with high energy conversion efficiency remains challenging. This study leverages the catechol and amino groups in polydopamine (PDA) molecules to achieve simultaneous loading of Na+ and Cl– ions. Through potassium persulfate oxidation to protonate PDA's amino groups for Cl– adsorption, followed by Tris-base pH adjustment to facilitate Na+ binding with catechol groups, we successfully confined sodium chloride (NaCl) within PDA via layer-by-layer assembly, creating highly efficient NaCl@PDA microwave-responsive nanoparticles. Systematic investigation revealed that toluene and potassium persulfate dosage significantly influenced nanoparticle size, with 2 g of potassium persulfate yielding uniform spherical nanoparticles (≈149 nm diameter) with well-defined morphology. Through systematic optimization of the NaCl content, we found that a loading of 36.0 wt % endowed the nanoparticles with exceptional thermal conversion performance under ultralow-power microwave irradiation (2 W, 2450 MHz), achieving 53 °C within 600 s demonstrating 1.7-fold and 1.4-fold faster heating rates compared to physiological saline and pure PDA nanoparticles, respectively. The synthesized nanoparticles exhibit superior microwave responsiveness, showing great potential for applications in microwave thermal therapy and stealth coating technologies.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"11 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrogel Microneedle-Enabled In Situ Monitoring of Leaf Nitric Oxide for Evaluating NO Nanoprodrug-Mediated Salt Stress Alleviation in Maize","authors":"Yuying Wang,Jiayao Wulan,Qiliang Huang,Pengyue Zhao,Chong Cao,Yuqing Lin,Lidong Cao","doi":"10.1021/acsami.6c16130","DOIUrl":"https://doi.org/10.1021/acsami.6c16130","url":null,"abstract":"Chemical signals in living plants are spatially confined, rapidly consumed, and strongly dependent on the delivery history of exogenous regulators, creating a need for bioelectronic interfaces that can interrogate molecular dynamics directly within intact tissues. Here, we integrate a nitric oxide (NO) nanoprodrug with a conductive hydrogel microneedle platform to connect controlled molecular delivery, in planta electrochemical readout, and downstream biological responses in living maize. The working electrode comprises a poly(vinyl alcohol)/aramid nanofiber (PVA/ANF) hydrogel containing FeMo-N/C and an MXene conductive network. The hydrated microneedle architecture provides tissue-conformal contact and analyte transport, FeMo-N/C enhances the NO-associated electrochemical response, and MXene improves interfacial charge transfer. The resulting platform responds to NO from 1 nM to 100 μM with a detection limit of 0.3 nM and discriminates NO from representative electroactive plant interferents. Chitosan nanoparticles containing S-nitroso-mercaptosuccinic acid were used to moderate NO release, and the microneedle interface resolved treatment-dependent leaf signals over 7 days under salt stress. Signal attenuation by the NO scavenger cPTIO supported the NO-related origin of the electrochemical response. The time-resolved readout was accompanied by improved growth, reduced lipid peroxidation, changes in osmotic and antioxidant responses, and altered expression of stress-responsive genes. This delivery–bioelectronics–analysis framework provides a materials-based strategy for evaluating reactive nanoprodrugs and interrogating transient chemical signaling in living plants.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"63 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sn/Cl Co-Doped ZnO Cathode Interfacial Layer for High-Performance Organic Photodetectors","authors":"Zhihuan Miao,Muyi Fu,Runze Zhou,Kaiming Zhu,Yao Xu,Zhikun Yu,Kai Zhang","doi":"10.1021/acsami.6c15059","DOIUrl":"https://doi.org/10.1021/acsami.6c15059","url":null,"abstract":"Organic photodetectors (OPDs) hold significant promise for applications spanning medical monitoring, bioimaging and night vision due to their unique advantages, such as flexibility, light weight, and potential for large-area fabrication. Nevertheless, the dark current density (Jd) of OPDs exhibits a pronounced increase under applied reverse bias, which consequently degrades the specific detectivity (D*). To tackle this challenge, this work proposes an interface engineering strategy based on Sn/Cl co-doped ZnO (SCZO). The doping effectively reduces oxygen defects in ZnO, causing the valence band maximum (VBM) to shift downward, thereby suppressing hole injection under bias and reducing Jd. Experiments show that the SCZO-based device exhibits a Jd of 4.05 × 10–11 A cm–2 at –0.1 V, nearly one order of magnitude lower than that of the control device (4.07 × 10–10 A cm–2). Notably, the SCZO-based OPD enables real-time and accurate monitoring of human heart rate, demonstrating its considerable potential for health-monitoring applications. Furthermore, OPDs incorporating the SCZO interface exhibit excellent imaging performance under 820 nm illumination. These findings underscore the significant potential of SCZO-based OPDs for flexible, wearable health monitoring and near-infrared imaging applications.","PeriodicalId":5,"journal":{"name":"ACS Applied Materials & Interfaces","volume":"10 1","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}