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生物化学进展(英文)最新文献

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Synthesis and Anticandidosic Activities of Some 3-Imidazo[1,2-a]Pyridinyl-1-Arylpropenone Derivatives 3-咪唑[1,2-a]吡啶基-1-芳基丙烯衍生物的合成及抗抗药活性研究
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.124008
Kouassi Francesco Adingra, S. Coulibaly, Kacou Alain, M. Ouattara, D. Sissouma
{"title":"Synthesis and Anticandidosic Activities of Some 3-Imidazo[1,2-a]Pyridinyl-1-Arylpropenone Derivatives","authors":"Kouassi Francesco Adingra, S. Coulibaly, Kacou Alain, M. Ouattara, D. Sissouma","doi":"10.4236/abc.2022.124008","DOIUrl":"https://doi.org/10.4236/abc.2022.124008","url":null,"abstract":"","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70476048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Superoxide Anion Release by Human Blood Phagocytes Can Increase the Microbicidal Activity Induced by a New Microemulsioned System Containing Cotton Oil 一种新型棉油微乳化系统诱导的人血液吞噬细胞释放超氧阴离子可提高其杀微生物活性
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.126018
Luana Cristina da Silva Ramos, A. H. F. Torres, Letícia Damas Leão Dalcin, K. P. G. Silva, Luana Gabriela Silva de Freitas, Mahmi Fujimori, D. L. Fagundes, E. L. França, A. França
{"title":"Superoxide Anion Release by Human Blood Phagocytes Can Increase the Microbicidal Activity Induced by a New Microemulsioned System Containing Cotton Oil","authors":"Luana Cristina da Silva Ramos, A. H. F. Torres, Letícia Damas Leão Dalcin, K. P. G. Silva, Luana Gabriela Silva de Freitas, Mahmi Fujimori, D. L. Fagundes, E. L. França, A. França","doi":"10.4236/abc.2022.126018","DOIUrl":"https://doi.org/10.4236/abc.2022.126018","url":null,"abstract":"","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantification of Tannins in Four Species of Genus Mucna Seeds 四种粘属植物种子中单宁含量的测定
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.124007
A. Mbaiogaou, S. Mbaihougadobe, S. M. Betoloum, A. Hema, E. Palé, Samaté Dorosso Abdoul
{"title":"Quantification of Tannins in Four Species of Genus <i>Mucna</i> Seeds","authors":"A. Mbaiogaou, S. Mbaihougadobe, S. M. Betoloum, A. Hema, E. Palé, Samaté Dorosso Abdoul","doi":"10.4236/abc.2022.124007","DOIUrl":"https://doi.org/10.4236/abc.2022.124007","url":null,"abstract":"","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70476033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stability Monomolecular Properties of Archaeal Tetraether Lipids Layers onto Solid Substrates 固体底物上古细菌四醚脂质层的单分子稳定性
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.121003
S. Vidawati, U. Bakowsky
{"title":"Stability Monomolecular Properties of Archaeal Tetraether Lipids Layers onto Solid Substrates","authors":"S. Vidawati, U. Bakowsky","doi":"10.4236/abc.2022.121003","DOIUrl":"https://doi.org/10.4236/abc.2022.121003","url":null,"abstract":"","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phenoloxidase and Melanization Innate Immune Activities in Green Darner Dragonfly Nymphs (Anax junius) 绿翅蜻蜓若虫酚氧化酶与黑色素化的先天免疫活性
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.124011
Mark Merchant, M. Mcclure
{"title":"Phenoloxidase and Melanization Innate Immune Activities in Green Darner Dragonfly Nymphs (<i>Anax junius</i>)","authors":"Mark Merchant, M. Mcclure","doi":"10.4236/abc.2022.124011","DOIUrl":"https://doi.org/10.4236/abc.2022.124011","url":null,"abstract":"Insects in the Order Odonata are highly subject to infection by gregarine parasites. However, despite the important ecological roles that insects play in every ecosystem in which they exist, little research has been devoted to the description of insect immunity. Insects rely heavily on the rapid actions of innate immune mechanisms to prevent infection. We characterized the melanization response in the hemolymph of green darner dragonfly (Anax junius) nymphs. Incubation of chymotrypsin-activated hemolymph with L-DOPA resulted in volume- and time-dependent production of dopaquinone via the phenoloxidase (PO) enzyme, with biphasic accumulation of product. The PO activity was temperature-dependent, with a stepwise increase from 20˚C 35˚C and maximum activity measured at 35˚C - 40˚C. The formation of product was also inhibited in a concentration-dependent manner by diethyl-carbonate, a specific inhibitor of PO activity, which indicated that the observed activity was due to the presence of PO enzyme. The rate of formation and quantity of melanin was dependent on exposure to different titers of bacteria. This is the first characterization of both PO activity and melanization response in green darner dragonflies.","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Positive Effects of Proprietary Undenatured β-Glucans on Stressed Marine Life 专有未变性β-葡聚糖对逆境海洋生物的积极作用
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.125013
B. Kristiansen, R. Amen
{"title":"The Positive Effects of Proprietary Undenatured <i>β</i>-Glucans on Stressed Marine Life","authors":"B. Kristiansen, R. Amen","doi":"10.4236/abc.2022.125013","DOIUrl":"https://doi.org/10.4236/abc.2022.125013","url":null,"abstract":"The safety of beta-glucans, including undenatured beta-glucan (UDBG), has been exhaustively studied over the recent past and has shown to be safe and efficacious in rodents as well as in humans with less than optimal immune systems. As such, we sought to find the effect of UDBG on certainly stressed crustaceans and fish. The survival of shrimp larvae fed the UDBG and other diets was measured on day 16. The diet containing 11.7% UDBG reduced larvae mortality by 18%; which is almost twice as much as the mortality reduced by the MacroGard diet, and up to 19.5% less than a standard Commercial Diet. In an effort to understand how UDBG protects against stressed marine life, UDBG was given to LPS-challenged trout. The UDBG positively influenced the level of transcription of several genes relevant to the immune system and overall health of the trout. The experimental findings indicated that UDBG: 1) modifies inflammatory responses, 2) makes responses more flexible and ver-satile, 3) protects from cellular stress, and 4) enhances “effector” mechanisms. Importantly, there was no evidence of immune system over-activity.","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and Efficacy of a Proprietary Undenatured Beta-Glucan on Different Human Populations 专有的未变性β -葡聚糖在不同人群中的安全性和有效性
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.121002
B. Kristiansen, R. Amen
{"title":"Safety and Efficacy of a Proprietary Undenatured Beta-Glucan on Different Human Populations","authors":"B. Kristiansen, R. Amen","doi":"10.4236/abc.2022.121002","DOIUrl":"https://doi.org/10.4236/abc.2022.121002","url":null,"abstract":"After proving safety in animal and human models, a series of clinical trials were conducted to examine the administration of 1 mg/mL bid of an undenatured beta-glucan on the immune system; and on self-perceived effects on subjects’ quality of life (QoL) using a Visual Analogue Scale (VAS). In one study, a subject population that was self-perceived to be fatigued was administered an undetaured beta-glucan, to determine if this supplementation affected their quality-of-life as a result of an increased immune system response. 44 subjects were administered 1 mg/mL bid of the undenatured be-ta-glucan (Lentinex ® ) for four weeks. Prior to the beginning of the administration, and following the four-week administration period, the subjects were asked to fill out a quality-of-life VAS questionnaire. The changes in the two questionnaires revealed differences that occurred as a result of the beta-glucan administration. More than 75% of the subjects scored “better” (more than 1 cm on the VAS) with regard to feeling in a good mood, and feeling rested. More than 60% increased their energy and reduced their tiredness and exhaustion, and 70% felt less stressed. In a second study, subjects aged 40 years and older, believed to be in good general health, seeking therapy for tired-ness/exhaustion/fatigue or similar conditions (neurasthenia) which were administered 1 mg/mL bid Lentinex ® . The overall results indicated that the subjects felt significantly better (mean VAS = 5.91) after the not functioning at optimal levels.","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Pesticide-Induced Alterations of Esterase and Antioxidant Enzymes of Aquatic Organisms Oreochromis mossambicus and Xenopus laevis 农药诱导的水生物沧鱼和非洲爪蟾酯酶和抗氧化酶的变化
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.126023
Ronald Ndlovu, N. Basopo
{"title":"Pesticide-Induced Alterations of Esterase and Antioxidant Enzymes of Aquatic Organisms <i>Oreochromis mossambicus</i> and <i>Xenopus laevis</i>","authors":"Ronald Ndlovu, N. Basopo","doi":"10.4236/abc.2022.126023","DOIUrl":"https://doi.org/10.4236/abc.2022.126023","url":null,"abstract":"","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70476017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Photoactivated Hypericin on Growth and Antibiotic Susceptibility of Hospital-Related Staphylococcus aureus and Enterococcus sp. Clinical Strains 光活化金丝桃素对医院相关性金黄色葡萄球菌和肠球菌临床菌株生长及药敏的影响
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.124010
M. Nagyová, L. Siegfried, D. Jancura, Z. Nadova
{"title":"Effect of Photoactivated Hypericin on Growth and Antibiotic Susceptibility of Hospital-Related <i>Staphylococcus aureus</i> and <i>Enterococcus sp.</i> Clinical Strains","authors":"M. Nagyová, L. Siegfried, D. Jancura, Z. Nadova","doi":"10.4236/abc.2022.124010","DOIUrl":"https://doi.org/10.4236/abc.2022.124010","url":null,"abstract":"","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70476099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Haptoglobin Phenotype Impact Infection Mortality? 珠蛋白表型影响感染死亡率吗?
生物化学进展(英文) Pub Date : 2022-01-01 DOI: 10.4236/abc.2022.125012
Akissi Joelle Koffi, H. Ahiboh, Philémond By, D. Gabillard, R. Affi, Francisk Kouakou, A. Inwoley
{"title":"Does Haptoglobin Phenotype Impact Infection Mortality?","authors":"Akissi Joelle Koffi, H. Ahiboh, Philémond By, D. Gabillard, R. Affi, Francisk Kouakou, A. Inwoley","doi":"10.4236/abc.2022.125012","DOIUrl":"https://doi.org/10.4236/abc.2022.125012","url":null,"abstract":"","PeriodicalId":59114,"journal":{"name":"生物化学进展(英文)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70475657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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