Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova最新文献

{"title":"[Circadian activity and light hygiene as predictors of sleep quality in children and adults: an actigraphic study in the family environment].","authors":"D G Gubin, Yu V Nelaeva, S A Smetanina, O A Beley, I M Petrov","doi":"10.17116/jnevro202612605217","DOIUrl":"10.17116/jnevro202612605217","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the associations between sleep parameters, specifically duration and efficiency, and circadian activity and blue light exposure (BLE) in children and adults within a family environment.</p><p><strong>Material and methods: </strong>In May 2025, a week-long actigraphic study was conducted in Tyumen, Russia, with 177 participants, comprising 88 children (mean age 10.56±2.17 years; 52.3% female) and 89 adults (mean age 37.56±8.14 years; 86.5% female). The study assessed sleep duration (SD), sleep efficiency (SE), relative nonparametric circadian activity amplitude (RA), intra-daily variability of BLE (BLE IV), inter-daily stability of BLE (BLE IS), and the integral index of light hygiene, defined as normalized parametric amplitude BLE (NA CC). Statistical analyses included nonparametric tests, correlation analysis, and linear regression models adjusted for sex and age.</p><p><strong>Results: </strong>Children demonstrated significantly longer sleep duration (by 49 minutes; 8:16±0:57 h vs. 7:27±1:04 h; <i>p<</i>0.001) and higher sleep efficiency (90.70±3.44% vs. 89.01±5.36%; <i>p=</i>0.031) compared to adults. Additionally, children exhibited a higher NA CC (1.48±0.19 vs. 1.42±0.17, <i>p=</i>0.016). Sleep duration and efficiency were positively correlated (<i>r</i>=0.300, <i>p<</i>0.0001). RA was identified as a strong independent predictor of both SD and SE across all groups (<i>p<</i>0.001; <i>η</i>²=0.142-0.276). Among adults, higher SE was significantly associated with greater BLE inter-daily stability (<i>r</i>=0.253, <i>p=</i>0.017; <i>β</i>=0.248, <i>p=</i>0.019) and lower BLE intra-daily variability (<i>r</i>=-0.221, <i>p=</i>0.038; <i>β</i>=-0.257, <i>p=</i>0.016).</p><p><strong>Conclusions: </strong>Children exhibit greater sleep duration and efficiency, as well as more robust circadian rhythmicity, compared to adults. In adults, consistent daily blue light exposure, particularly inter-daily stability, is a key determinant of sleep quality. These findings underscore the significance of circadian light hygiene within the family environment and support the implementation of biodynamic lighting to enhance sleep quality across age groups.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 5. Vyp. 2","pages":"17-22"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148213534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical and neurophysiological examination of participants in modern warfare].","authors":"S A Galkin, A V Didenko, O V Roshchina, T A Oshkina, N A Bokhan","doi":"10.17116/jnevro202612606138","DOIUrl":"https://doi.org/10.17116/jnevro202612606138","url":null,"abstract":"<p><strong>Objective: </strong>To identify neurophysiological correlates of mental disorders in individuals who have participated in modern warfare.</p><p><strong>Material and methods: </strong>A total of 30 participants from a special military operation, aged 30-43 years (median age: 36 years), were examined. Diagnostic evaluations and clinical verification of mental disorders were conducted by the attending physician in accordance with the International Classification of Diseases, 10^th Revision (ICD-10). The psychometric assessment utilized standardized questionnaires and scales: the Combat Exposure Scale (CES, by T. Keane), the Impact of Event Scale - Revised (IES-R), the Insomnia Severity Index (ISI), the Hamilton Anxiety Rating Scale (HARS), the Hamilton Depression Rating Scale (HDRS-17), and the Alcohol Use Disorders Identification Test (AUDIT). Electroencephalogram (EEG) parameters were recorded following the international 10-20% system. A clinical conclusion was drawn from the obtained EEG data, and a quantitative analysis of the background sample was performed, including the calculation of the absolute spectral powers of theta, alpha, and beta rhythms.</p><p><strong>Results: </strong>The analysis revealed a complex and polymorphic presentation of mental disorders among combatants, characterized by a high prevalence of comorbidity due to the multifaceted nature of the underlying pathogenetic mechanisms. The most common diagnostic categories within the surveyed cohort were F0 'Organic, including symptomatic, mental disorders' (73.3%; <i>n=</i>22), and F4 'Neurotic, stress-related and somatoform disorders' (56.7%; <i>n=</i>17). Notably, post-traumatic stress disorder (PTSD) was recorded in 47.1% of cases (<i>n=</i>8) within this subgroup, while it was observed in only 26.7% of the overall patient sample. Psychometric analysis indicated that participants exhibited pronounced symptoms of PTSD, depression, anxiety, and sleep disturbances. The identified mental disorders were accompanied by alterations in the brain's bioelectrical activity, predominantly characterized by desynchronization of cortical rhythms, a diffuse increase in low-amplitude beta activity, and disorganization (polyrhythmicity) of the EEG.</p><p><strong>Conclusions: </strong>The findings of this study indicate that the predominant clinical and diagnostic categories among participants of modern warfare are organic and neurotic mental disorders, each exhibiting distinctive features in the EEG profile.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 6","pages":"38-44"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148341425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The potential of a selective anxiolytic afobazole in clinical practice].","authors":"O S Levin","doi":"10.17116/jnevro202612606129","DOIUrl":"https://doi.org/10.17116/jnevro202612606129","url":null,"abstract":"<p><p>Anxiety disorders represent the most prevalent category of mental health issues, particularly affecting individuals with chronic somatic conditions. Choosing an appropriate treatment can be challenging due to the frequent side effects associated with many anxiolytics and antidepressants, as well as the risk of drug-drug interactions, which is especially pertinent for patients with comorbidities. Afobazol was developed as a safer alternative to traditional benzodiazepine tranquilizers. Its active ingredient, fabomotizole, is a selective anxiolytic that operates through a unique mechanism designed to restore the structure and function of damaged nerve cells. The effectiveness and safety of fabomotizole have been investigated in clinical trials involving various anxiety disorders, including those associated with somatic pathology. Randomized clinical trials focused on patients with generalized anxiety disorder and adjustment disorder have demonstrated a significant anxiolytic effect of fabomotizole, comparable to that of benzodiazepines and significantly more effective than a placebo. Further studies confirmed its benefits in stabilizing autonomic functions, delivering antidepressant effects, and enhancing overall activity (antiasthenic effects). A review of clinical studies involving patients with comorbid conditions revealed fabomotizole's efficacy and good tolerability, with no significant drug-drug interactions, and a favorable impact on the management and prognosis of these conditions. The extended-release formulation of fabomotizole (AFOBAZOL RETARD) enhances patient compliance, thereby ensuring effective treatment for anxiety disorders and related conditions.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 6","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148341533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Bidirectional links between sleep deprivation and neurodegenerative diseases].","authors":"A V Zakharov, Yu S Komarova, P M Moskvitina, O N Pavlova, N P Romanchuk, M S Sergeeva, I V Shirolapov","doi":"10.17116/jnevro202612605274","DOIUrl":"10.17116/jnevro202612605274","url":null,"abstract":"<p><p>Sleep is essential for maintaining homeostatic functions, supporting optimal brain activity, and facilitating recovery processes. The clinical consequences of sleep deprivation and sleep disorders require an integrated approach to diagnosis and therapy, as these conditions affect the progression and development of various diseases and systemic pathological processes. Sleep disturbances are a significant global health concern. This article reviews the potential impact and bidirectional associations between sleep deprivation and the risk of neurodegenerative diseases.The mechanisms underlying the imbalance between the formation and clearance of abnormal proteins, which are central to the pathogenesis of proteinopathies associated with sleep disorders or deprivation, are examined. Although treating Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions remains challenging, recent research may enable prevention and targeted interventions at early stages, including extensive screening and modification of risk factors such as sleep deprivation and disturbance.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 5. Vyp. 2","pages":"74-80"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148213556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cultural adaptation of the Eating Disorder Examination Questionnaire (EDE-Q 6.0)].","authors":"M S Aslanova, N V Chernov, G P Kostyuk, E S Sgonnik","doi":"10.17116/jnevro202612602197","DOIUrl":"10.17116/jnevro202612602197","url":null,"abstract":"<p><strong>Objective: </strong>Adaptation of the Russian version of the Eating Disorder Examination Questionnaire (EDE-Q) 6.0, and assessment of its psychometric properties.</p><p><strong>Material and methods: </strong>The study sample included 476 females, 208 with a confirmed diagnosis of an eating disorder (ED), and the rest were a healthy group. In addition to the Russian version of EDE-Q 6.0, the respondents completed a socio-demographic and other questionnaires widely used for the PPD diagnosis: the Eating Attitudes Test (EAT-26), the Eating Behavior Scale (EBS), and the Dutch Eating Behavior Questionnaire (DEBQ).</p><p><strong>Results: </strong>As a result of the confirmatory factor analysis, the four-factor structure of the Russian-language version of EDE-Q 6.0 was confirmed (Restraint, Eating concern, Shape concern, Weight concern). The internal consistency of the scales' questions is high (Cronbach's <i>α</i>=0.82-0.89). The clinical and healthy groups showed significant differences (<i>p<</i>0.05) on all scales, underscoring the questionnaire's diagnostic value. Correlations with the scales of other questionnaires used to diagnose ED confirmed the external validity of the Russian-language version of EDE-Q 6.0. The retest reliability assessment also showed high stability of the questionnaire's results over time (Spearman's Rho ranged from 0.72 to 0.89).</p><p><strong>Conclusion: </strong>The Russian version of EDE-Q 6.0 demonstrates good psychometric properties and is suitable for use in clinical and scientific practice for screening and monitoring the development of ED in the Russian female population.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 2","pages":"97-108"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The iron curtain of medicine: why soviet criticism of lobotomy failed to reach Israel].","authors":"T Kichli Borochovsky","doi":"10.17116/jnevro2026126021153","DOIUrl":"10.17116/jnevro2026126021153","url":null,"abstract":"<p><p>The discrepancies in international approaches to psychosurgery during 1940-1960 are analyzed, focusing on the criticisms published in the Soviet medical literature and on its opposition to the ongoing Western practice. While the S.S. Korsakov Journal of Neurology and Psychiatry and related Soviet publications led the international opposition to lobotomy through systematic scientific and ethical criticism, this procedure continued to be used uncontrollably in Western medical systems. Based on a comprehensive archival review of a clinical case of a Holocaust survivor who underwent a lobotomy in Israel in late 1951 - one year after the Soviet ban - this paper demonstrates how miscommunication of medical knowledge, ideological barriers, and institutional cultures shaped therapeutic practices in various health systems. The study contributes to understanding how, if taken into account at the international level, the results of scientific work could prevent thousands of unnecessary medical interventions.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 2","pages":"153-157"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Frequency of 5q spinal muscular atrophy in adults with unspecified neuromuscular diseases].","authors":"A V Petrokovskaia, O V Gilvanova, D A Degterev, V D Tkachenko, V V Lebedev","doi":"10.17116/jnevro202612603168","DOIUrl":"10.17116/jnevro202612603168","url":null,"abstract":"<p><strong>Objective: </strong>To assess the prevalence of 5q spinal muscular atrophy (SMA) among adult patients with undifferentiated neuromuscular disorders.</p><p><strong>Material and methods: </strong>Prospective study of 50 patients (19-78 years) presenting ≥1 feature of 5q SMA: areflexia, proximal weakness, fasciculations, neurogenic EMG changes, atrophy, calf hypertrophy, or elevated creatine kinase (CK). Molecular testing (MLPA/melting curve analysis of <i>SMN1</i>/<i>SMN2</i>) was performed.</p><p><strong>Results: </strong>5q SMA was confirmed in one female patient (2% [95% CI 0.05-10.6]), who was found to have a homozygous deletion of exons 7-8 in the <i>SMN1</i> gene. Her clinical presentation included proximal lower limb weakness and neurogenic EMG changes, but she lacked areflexia and had normal CK levels. For 29 years, she had been misdiagnosed with «unspecified myopathy»(G72.9).</p><p><strong>Conclusion: </strong>The findings highlight the need to include 5q SMA in the differential diagnosis of adult patients with undifferentiated neuromuscular disorders. Optimizing diagnostic algorithms and enhancing epidemiological monitoring in this age group are essential to reduce diagnostic delays.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 3","pages":"68-73"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Acteoside: neurobiological activity spectrum, potential in the treatment of age-associated neurodegenerative diseases].","authors":"M A Berezutsky, T A Andronova, Yu V Belonogova, N A Durnova","doi":"10.17116/jnevro202612604141","DOIUrl":"10.17116/jnevro202612604141","url":null,"abstract":"<p><p>Acteoside (verbascoside, kusaginin) is a phenylethanoid glycoside, which is found in more than 200 species of plants and is characterized by a wide range of pharmacological activity. The results of studies on the neurobiological effects of acteoside, which can be used in the treatment of Alzheimer's disease (AD) and Parkinson's disease (PD), were summarized and analyzed. The PubMed, Scopus, Google Scholar, and e-Library databases were searched for the following keywords: «acteoside», «Alzheimer's disease», «Parkinson's disease», «pathological activation of microglia», «neurotrophic effect», «endoplasmic reticulum stress», «protection of neurons from beta-amyloid», «inhibition of tau protein hyperphosphorylation», «death of dopaminergic neurons», «aggregation of <i>α</i>-synuclein», «cognitive and motor impairment». Experimental studies have shown the ability of acteoside to inhibit pathological activation of microglia, exert a neurotrophic effect, inhibit endoplasmic reticulum stress, protect neurons from beta-amyloid, inhibit tau-protein hyperphosphorylation, reduce intracellular Ca²⁺ mobilization dysfunction, protect neurons from glutamate-induced neurotoxicity, prevent dopaminergic neuron death, reduce <i>α</i>-synuclein aggregation, and attenuate cognitive and motor impairments. This compound has good prospects for chemical modification, as its structure features several reactive sites. In the future, acteoside may be used as a multi-purpose complex therapy for AD and PD.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 4","pages":"41-47"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147943877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Antiretroviral therapy-associated polyneuropathy in patients with HIV infection].","authors":"N E Seksyaev, Yu V Karakulova, A A Vychugzhanina","doi":"10.17116/jnevro202612604128","DOIUrl":"10.17116/jnevro202612604128","url":null,"abstract":"<p><p>This paper reviews the issue of polyneuropathy caused by antiretroviral therapy (ART), which has dramatically changed the outcomes of human immunodeficiency virus (HIV) infection, significantly increasing the life expectancy of patients, and reducing the frequency of opportunistic infections. Long-term use of ART is associated with many complications, with polyneuropathy occupying a special place and accounting for 20-50% of all ART complications. Polyneuropathy is manifested by symmetrical distal sensory impairments combined with neuropathic pain, which significantly reduces the quality of life of patients and can reduce compliance to treatment. The article presents the key features of differential diagnosis of ART-associated, HIV-associated, and chemotherapy-induced polyneuropathies; their main pathogenetic features are described and the options for prevention and treatment of ART- associated polyneuropathy are analyzed.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 4","pages":"28-34"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147943937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of the neuroprotective activity of Mexidol in a model of hemorrhagic stroke].","authors":"A V Shchulkin, I V Chernykh, S K Pravkin, Yu V Abalenikhina","doi":"10.17116/jnevro202612603240","DOIUrl":"10.17116/jnevro202612603240","url":null,"abstract":"<p><strong>Objective: </strong>To comprehensively evaluate the neuroprotective potential of Mexidol following systemic administration in various dosage forms in a model of hemorrhagic stroke.</p><p><strong>Material and methods: </strong>The study was performed on 130 outbred male rats, weighing 180-200 g and aged 7-8 weeks. All animals were divided into 3 series: Series 1 - intravenous administration of Mexidol at doses of 50 and 100 mg/kg; Series 2 - intramuscular administration at doses of 50 and 100 mg/kg; Series 3 - intragastric administration at doses of 50, 100, and 200 mg/kg. Acute hemorrhagic stroke was modeled by administering autologous blood at a volume of 0.05 ml/kg body weight into the region of the internal capsule of the right hemisphere. Mexidol administration was initiated 30 minutes after modeling acute focal stroke. Twenty-four hours after the surgery, the severity of neurological deficit was assessed using the McGraw Stroke-Index Scale modified by I.V. Gannushkina. Subsequently, the animals were euthanized, the brain was isolated, fixed in formalin, and tomography was performed.</p><p><strong>Results: </strong>Intravenous administration of Mexidol at a dose of 100 mg/kg led to a statistically significant reduction in the severity of clinical symptoms 24 hours after surgery compared to control animals. Intramuscular administration produced a similar effect at doses of 50 and 100 mg/kg, while intragastric administration did so at doses of 100 mg/kg and 200 mg/kg. Intravenous and intramuscular administration of Mexidol at doses of 50 and 100 mg/kg did not affect the size of the brain lesion in rats, whereas intragastric administration of Mexidol at a dose of 200 mg/kg led to its reduction.</p><p><strong>Conclusion: </strong>The obtained results indicate that, in cases of small intracranial hematomas (e.g., those remaining after surgical removal of the initial hematoma), Mexidol exerts a pronounced neuroprotective effect.</p>","PeriodicalId":56370,"journal":{"name":"Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova","volume":"126 3. Vyp. 2","pages":"40-45"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147629374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}