Journal of Microbiology Immunology and Infection最新文献

{"title":"Impacts of Pta-AckA pathway on CPS biosynthesis and type 3 fimbriae expression in Klebsiella pneumoniae","authors":"Tien-Huang Lin ,&nbsp;Chen-Yu Wang ,&nbsp;Chien-Chen Wu ,&nbsp;Ching-Ting Lin","doi":"10.1016/j.jmii.2024.10.002","DOIUrl":"10.1016/j.jmii.2024.10.002","url":null,"abstract":"<div><h3>Background</h3><div><em>Klebsiella pneumoniae</em> is a Gram-negative bacterium that can cause infections, especially in individuals with diabetes. Recently, more hypervirulent strains have emerged, posing a threat even to healthy individuals. Understanding how <em>K. pneumoniae</em> regulates its virulence factors is crucial. Acetyl-phosphate (AcP) is essential for bacterial metabolism and can affect virulence factor expression. However, the role of the Pta-AckA pathway, which regulates AcP levels, in <em>K. pneumoniae</em> pathogenesis remains unclear.</div></div><div><h3>Methods</h3><div>Deletion mutants lacking the <em>pta</em> and <em>ackA</em>, involved in AcP production and hydrolysis, were generated in <em>K. pneumoniae</em> CG43S3. Their effects on AcP levels, the patterns of global acetylated protein, capsular polysaccharide (CPS) amount, serum resistance, type 3 fimbriae expression, biofilm formation, and virulence in <em>G</em>. <em>mellonella</em> larva were assessed.</div></div><div><h3>Results</h3><div>Deletion of <em>ackA</em> in <em>K. pneumoniae</em> CG43S3 led to AcP accumulation, while <em>pta</em> deletion abolished AcP synthesis when grown in TB7+1 % glucose. This pathway influenced global protein acetylation, with <em>pta</em> deletion decreasing acetylation and <em>ackA</em> deletion increasing it. Additionally, <em>pta</em> deletion decreased the CPS amount, serum resistance, and type 3 fimbriae expression, while <em>ackA</em> deletion increased these factors. Furthermore, deleting <em>pta</em> and <em>ackA</em> attenuated the infected larva's virulence and death rate.</div></div><div><h3>Conclusion</h3><div>Our findings highlight the critical role of the Pta-AckA pathway in <em>K. pneumoniae</em> pathogenesis. This pathway regulates AcP levels, global protein acetylation, CPS production, serum resistance, and type 3 fimbriae expression, ultimately impacting virulence. The information provides insights into potential therapeutic targets for combating <em>K. pneumoniae</em> infection.</div></div>","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 48-55"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae","authors":"Kuang-Yao Chen ,&nbsp;Yi-Hsuan Lin ,&nbsp;Chien-Ju Cheng ,&nbsp;Yi-Hao Huang ,&nbsp;Sheng-Yu Lin ,&nbsp;Chyi-Liang Chen ,&nbsp;Cheng-Hsun Chiu","doi":"10.1016/j.jmii.2024.11.001","DOIUrl":"10.1016/j.jmii.2024.11.001","url":null,"abstract":"<div><h3>Background</h3><div><em>Angiostrongylus cantonensis</em> is a significant foodborne zoonotic parasite that causes severe neuropathological damage and symptoms in humans. Excretory-secretory products (ESPs) play a pivotal role in elucidating host-parasite interactions and can aid in penetrating host defensive barriers in helminths. Recently, secreted microRNAs have become important research targets for parasite-host communication. In this study, we determined the expression and function of novel microRNAs from <em>A. cantonensis</em> L5 ESPs and evaluated the effect of target microRNAs on the molecular mechanisms of mouse astrocytes.</div></div><div><h3>Methods</h3><div>Here, we employed next-generation sequencing (NGS) to establish the secreted microRNAs dataset. Next, we evaluated the effects of AcESPs-microRNAs in <em>A. cantonensis</em> ESPs treated astrocytes.</div></div><div><h3>Results</h3><div>First, we established the secreted microRNA dataset, and then comprehensively verified the characteristics. Novel microRNAs were initially detected, and their expression was found. Moreover, the prediction results showed that these secreted microRNAs may regulate Wnt and mTOR signaling. Next, the data showed that the AcNOVEL55 microRNA reduced cell apoptosis generation via regulating the RhoA-Rock signaling pathway in <em>A. cantonensis</em> L5 ESPs treated mouse astrocytes. Moreover, we also demonstrated that the AcNOVEL31 microRNA can affect the inflammation activation via regulating the presenilin-1/GSK3B/β-catenin/NF-κB pathway. Finally, the concentrations of secreted IL-6 and IL-12 proteins were downregulated by AcNOVEL31 microRNA by influencing presenilin-1 expression.</div></div><div><h3>Conclusion</h3><div>This is the first study to verify the molecular functions of novel microRNAs secreted by <em>A. cantonensis.</em> The discovery of the microRNA mechanisms by which cross-species parasitic nematodes influence hosts has advanced research on host-parasitic nematode interactions.</div></div>","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 128-137"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cryptococcosis in wait-listed liver transplant candidates: Prevalence, manifestations, and risk factors","authors":"Wan-Ting Tsai ,&nbsp;Aristine Cheng ,&nbsp;Yu-Chung Chuang ,&nbsp;Cheng-Maw Ho ,&nbsp;Yao-Ming Wu ,&nbsp;Ming-Chih Ho ,&nbsp;Hsin-Yun Sun ,&nbsp;Ray-Hung Hu ,&nbsp;Yee-Chun Chen","doi":"10.1016/j.jmii.2024.08.001","DOIUrl":"10.1016/j.jmii.2024.08.001","url":null,"abstract":"<div><h3>Background</h3><div>Liver cirrhosis compromises immunity against cryptococcosis, and liver transplant recipients tend to develop the disease earlier after transplantation, possibly due to unrecognized pretransplant infection. We assessed the prevalence and characteristics of cryptococcosis among liver transplant candidates and whether pre-transplant cryptococcal antigen (CrAg) can detect the disease before transplantation.</div></div><div><h3>Methods</h3><div>We retrospectively included liver transplant candidates in a tertiary hospital during 2017–2022. Serum CrAg and pulmonary computed tomography were incorporated in routine transplant evaluation. Other investigations were done if indicated. Cryptococcosis was diagnosed by positive culture or CrAg. Risk factors for cryptococcosis were also assessed.</div></div><div><h3>Results</h3><div>Of the 377 candidates with a median MELD-Na score of 18, 84.4% had hepatitis B virus (HBV) infection. Cryptococcosis was diagnosed in 10 (2.6%) candidates, by CrAg in 6, culture in 2, or both in 2. Only 3 had fever, and 3 were asymptomatic; 7 had pulmonary cryptococcosis. Of the 10 candidates with cryptococcosis, one underwent transplantation after 143-day antifungals. Of the 87 candidates undergoing liver transplantation, one (1.2%) recipient developed cryptococcosis 14 days post-transplant with negative CrAg three weeks before transplantation. HBsAg-positive chronic HBV infection with HBV DNA loads &lt;2000 IU/mL was significantly associated with cryptococcosis (odds ratio 4.4, 95% confidence interval 1.2–16.5, p = 0.03) after the adjustment of MELD-Na score.</div></div><div><h3>Conclusions</h3><div>The prevalence of cryptococcosis was 2.6% among our liver transplant candidates and CrAg detected 80% of the cases. Disease presentation was mild and pulmonary disease predominated. HBsAg-positive chronic HBV infection with HBV DNA loads &lt;2000 IU/mL was significantly associated with cryptococcosis.</div></div>","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 103-111"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142207781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of global transcriptomes for nontyphoidal Salmonella clinical isolates from pediatric patients with and without bacteremia after their interaction with human intestinal epithelial cells in vitro","authors":"Buyandelger Batsaikhan ,&nbsp;Pei-Chun Lin ,&nbsp;Katsumi Shigemura ,&nbsp;Yu-Wei Wu ,&nbsp;Reo Onishi ,&nbsp;Pei-Ru Chang ,&nbsp;Hung-Yen Cheng ,&nbsp;Shiuh-Bin Fang","doi":"10.1016/j.jmii.2024.09.002","DOIUrl":"10.1016/j.jmii.2024.09.002","url":null,"abstract":"<div><h3>Background</h3><div>Nontyphoidal <em>Salmonella</em> (NTS) outbreaks of invasive diseases are increasing. Whether the genetic diversity of invasive NTS correlates with the clinical characteristics and bacteremia development in NTS infections remains unclear. In this study, we compared the global transcriptomes between bacteremic and nonbacteremic NTS strains after their interaction with human intestinal epithelial cells <em>in vitro</em>.</div></div><div><h3>Methods</h3><div>We selected clinical isolates obtained from stool and blood samples of patients with or without bacteremia and patients with high and low C-reactive protein (CRP) levels. The bacterial RNA samples were isolated after coculturing with Caco-2 cells for RNA sequencing and subsequent analyses.</div></div><div><h3>Results</h3><div>CRP is an unreliable predictive maker for NTS bacteremia with a median CRP level of 1.6 mg/dL. Certain <em>Salmonella</em> Pathogenicity Island (SPI)-1 genes (<em>sipC</em>, <em>sipA</em>, <em>sicA</em>, <em>sipD</em>, and <em>sipB</em>), SPI-2 genes (<em>ssaP</em>, <em>ssrA</em>, and <em>ssaS</em>), and six SPI-4 genes (<em>siiA</em>, <em>siiB</em>, <em>siiC</em>, <em>siiD</em>, <em>siiE</em>, and <em>siiF</em>) remained upregulated in the bacteremic blood-derived strains but significantly downregulated in the nonbacteremic strains after their interaction with Caco-2 cells. The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analysis identified that arginine biosynthesis, ascorbate and aldarate metabolism, and phosphotransferase system pathways were activated in bacteremic NTS strains after Caco-2 cell priming.</div></div><div><h3>Conclusion</h3><div>CRP levels were not correlated with bacteremia development. Significant regulation of certain SPI genes in bacteremic NTS strains after Caco-2 cell priming; bacteremia development might be influenced by the host immune response and the extent to which specific metabolism pathways in NTS strains can be prevented from invading the bloodstream.</div></div>","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 38-47"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Mpox-specific IgG titers before and after breakthrough Mpox infection in an HIV-infected individual with viral suppression and prior 2-dose Mpox vaccination","authors":"Wang-Da Liu,&nbsp;Tai-Ling Chao,&nbsp;Sui-Yuan Chang,&nbsp;Chien-Ching Hung","doi":"10.1016/j.jmii.2024.10.003","DOIUrl":"10.1016/j.jmii.2024.10.003","url":null,"abstract":"","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 149-151"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Staphylococcus aureus, Enterococcus faecium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii from Raman spectra by Artificial Intelligent Raman Detection and Identification System (AIRDIS) with machine learning","authors":"Yu-Tzu Lin ,&nbsp;Hsiu-Hsien Lin ,&nbsp;Chih-Hao Chen ,&nbsp;Kun-Hao Tseng ,&nbsp;Pang-Chien Hsu ,&nbsp;Ya-Lun Wu ,&nbsp;Wei-Cheng Chang ,&nbsp;Nai-Shun Liao ,&nbsp;Yi-Fan Chou ,&nbsp;Chun-Yi Hsu ,&nbsp;Yu-Hui Liao ,&nbsp;Mao-Wang Ho ,&nbsp;Shih-Sheng Chang ,&nbsp;Po-Ren Hsueh ,&nbsp;Der-Yang Cho","doi":"10.1016/j.jmii.2024.11.014","DOIUrl":"10.1016/j.jmii.2024.11.014","url":null,"abstract":"<div><h3>Background</h3><div>Rapid and accurate identification of bacteria is required in order to develop effective treatment strategies. Traditional culture-based methods are time-consuming, while MALDI-TOF MS is expensive. The Raman spectroscopy, due to its relatively cost-effectiveness, offers a promising alternative for bacterial identification. However, its clinical utility still requires further validation.</div></div><div><h3>Methods</h3><div>In this study, the artificial intelligent Raman detection and identification system (AIRDIS) was implemented to identify bacterial species, including <em>Staphylococcus aureus</em> (n = 1290), <em>Enterococcus faecium</em> (n = 1020), <em>Klebsiella pneumoniae</em> (n = 1366), <em>Pseudomonas aeruginosa</em> (n = 1067), and <em>Acinetobacter baumannii</em> (n = 811). Raman spectra were collected, preprocessed, and analyzed by machine learning (ML).</div></div><div><h3>Results</h3><div>After training on 24,420 Raman spectra from 1221 isolates and testing on 4333 isolates, the AIRDIS demonstrated an area under the curve (AUC) of 0.99 for Gram classification, with accuracies of 97.64 % for Gram-positive bacteria and 98.86 % for Gram-negative bacteria. Spectral differences between Gram-positive and Gram-negative bacteria were linked to structural variations in their cell walls, such as peptidoglycan and lipopolysaccharides. At the species level, <em>S. aureus</em>, <em>E. faecium</em>, <em>K. pneumoniae</em>, <em>P. aeruginosa</em>, and <em>A. baumannii</em> were identified with high accuracy, ranging from 94.76 % to 96.88 %, with all species achieving an AUC of 0.99.</div></div><div><h3>Conclusions</h3><div>Validation with a large number of clinical isolates demonstrated Raman spectroscopy combined with ML excels in identification of five bacterial species associated with multidrug resistance. This finding confirms the clinical utility of the system while laying a solid foundation for the future development of antimicrobial resistance prediction models.</div></div>","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 77-85"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Entamoeba histolytica and Cryptosporidium co-infections in an HIV-infected, viral suppressed patient with a normal CD4 count","authors":"Chun-Hsien Chen ,&nbsp;Wei-Hung Cheng ,&nbsp;Ling-Shan Syue ,&nbsp;Ming-Chi Li ,&nbsp;Chin-Shiang Tsai","doi":"10.1016/j.jmii.2024.12.008","DOIUrl":"10.1016/j.jmii.2024.12.008","url":null,"abstract":"","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 154-155"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of the novel gene chip and restriction fragment length polymorphism (RFLP) methods for rapid detection of Mycobacterium tuberculosis complex in broth culture","authors":"Wen-Hung Wang ,&nbsp;Chun-Yu Lin ,&nbsp;Shu-Huei Jain ,&nbsp;Po-Liang Lu ,&nbsp;Yen-Hsu Chen","doi":"10.1016/j.jmii.2024.09.003","DOIUrl":"10.1016/j.jmii.2024.09.003","url":null,"abstract":"<div><h3>Background</h3><div>Tuberculosis (TB) is a major global public health issue. Prompt and accurate TB diagnosis is crucial for starting appropriate treatments and preventing the disease's spread. Current diagnostic techniques are either slow or expensive. This study aimed to create and evaluate a new, fast, highly reliable, and cost-effective TB detection method using a gene chip and Restriction Fragment Length Polymorphism (RFLP) analysis on Mycobacteria Growth Indicator Tubes (MGIT) specimens.</div></div><div><h3>Methods</h3><div>We assessed the effectiveness of a novel gene chip and RFLP methods targeting the 16S rRNA gene of <em>Mycobacterium tuberculosis</em> in 2000 MGIT culture-positive specimens. RFLP analysis identified the <em>Afe</em>I restriction site within the M. tuberculosis complex (MTBC) genome. Discrepancies were investigated through extensive sequencing and Cobas TaqMan PCR analysis, along with reviewing patient profiles.</div></div><div><h3>Results</h3><div>Both methods showed high efficacy in detecting MTBC in broth cultures, with the gene chip method achieving a sensitivity of 99.27 %, specificity of 98.35 %, and the RFLP method showing a sensitivity of 98.18 %, specificity of 99.31 %. False negatives in two isolates were due to a mutation in the <em>Afe</em>I site. Additionally, five cases showed MTBC presence when nontuberculous Mycobacterium species grew in cultures.</div></div><div><h3>Conclusion</h3><div>Our novel gene chip and RFLP methods are effective for rapid highly-reliable and cost-effective <em>M. tuberculosis</em> detection in MGIT specimens. Both gene chip and RFLP methods are suitable for resource-limited settings, offering an economical advantage. These methods have significant potential to improve clinical TB diagnosis.</div></div>","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 56-61"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142333172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Forty years of HIV infection and AIDS in Taiwan: Reflection on the past and looking toward the future","authors":"Sung-Hsi Huang ,&nbsp;Hsun-Yin Huang ,&nbsp;Stephane Wen-Wei Ku ,&nbsp;Po-Hsien Kuo ,&nbsp;Kuan-Yin Lin ,&nbsp;Guan-Jhou Chen ,&nbsp;Chia-Chi Lee ,&nbsp;Yen-Fang Huang ,&nbsp;Chien-Ching Hung","doi":"10.1016/j.jmii.2024.11.003","DOIUrl":"10.1016/j.jmii.2024.11.003","url":null,"abstract":"<div><div>We review the epidemiology, policies, and control programs of HIV infection in Taiwan in the past 40 years since the first case of HIV infection was diagnosed in 1984. With the introduction of combination antiretroviral therapy (ART) in Taiwan in 1997, the incidences of HIV-related opportunistic illnesses and mortality have significantly declined. However, despite improved access to HIV testing and treatment, late presentation of HIV infection remains common. Unprotected sex, particularly among men who have sex with men, continues to be the leading risk for HIV transmission after implementation of harm reduction program to control an outbreak of HIV infection among people who inject drugs that occurred in 2003–2007. The sequential introduction of well-tolerated, effective, single-tablet antiretroviral regimens has facilitated the implementation of “treat-all” policy in 2016, rapid ART initiation within 7 days of diagnosis in 2018, and same-day ART initiation in 2021 when immunochromatography was used for rapid confirmation of HIV infection. Government-funded pilot program of pre-exposure prophylaxis for HIV infection, which was launched in 2016 followed by wider enrollment of people at high risk for HIV acquisition in 2018, have contributed to sustained declines of the incidence of HIV infection since 2018, along with high rates of linkage to HIV care, ART initiation, viral suppression, and retention in care in Taiwan. Challenges remain to achieve HIV elimination and long-term successful management of HIV infection, which include stigma and discrimination, late presentation of HIV infection, and accelerated ageing with increasing rates of co-morbidities among people with HIV.</div></div>","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Pages 7-16"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Influenza and the risk of active tuberculosis occurrence among individuals with latent tuberculosis infection: A national cohort study in South Korea (2015–2020)” [J Microbiol Immunol Infect 57 (2024) 437–445 JOUMII-D-23-00515R1]","authors":"Jaehee Lee ,&nbsp;Hyewon Seo ,&nbsp;Dohyang Kim ,&nbsp;Jinseub Hwang ,&nbsp;Jin-Won Kwon","doi":"10.1016/j.jmii.2024.12.001","DOIUrl":"10.1016/j.jmii.2024.12.001","url":null,"abstract":"","PeriodicalId":56117,"journal":{"name":"Journal of Microbiology Immunology and Infection","volume":"58 1","pages":"Page 148"},"PeriodicalIF":4.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}