Neuroscience and Biobehavioral Reviews最新文献

{"title":"Bloody stressed! A systematic review of the associations between adulthood psychological stress and menstrual cycle irregularity","authors":"Marilou Poitras ,&nbsp;Fatima Shearzad,&nbsp;Aliya F. Qureshi,&nbsp;Cassandra Blackburn,&nbsp;Hélène Plamondon","doi":"10.1016/j.neubiorev.2024.105784","DOIUrl":"10.1016/j.neubiorev.2024.105784","url":null,"abstract":"<div><p>Regular menstruation is a key indicator of general health and irregular menstrual parameters have been associated with elevated risk of adverse health outcomes. While psychological stress is believed to contribute to abnormal menstruation, little is known of the effects of discrete psychological stressors, including the COVID-19 pandemic, on menstrual function. A systematic database search was performed and studies investigating the relation between psychological stress and menstrual cycle irregularity in otherwise healthy adults were included. Two independent investigators completed abstract and full-text screening, data extraction, and risk of bias assessment. In the 41 included studies, a variety of stressors were assessed, namely COVID-19 pandemic stress, academic stress, and occupational stress. Our review found most studies report an association between psychological stress and menstrual dysfunction, with the most common disruptions being irregular menstruation and abnormal menstrual flow. Our findings also underlined notable discrepancies in the operational definitions used in the study of menstrual disorders. These observations emphasize the importance of psychological stress as a modifiable risk factor associated with irregular menstruation.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141478052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transgenerational impacts of early life adversity: from health determinants, implications to epigenetic consequences","authors":"Cyrielle Holuka ,&nbsp;Nathalie Grova ,&nbsp;Eleftheria G. Charalambous ,&nbsp;Jeanne Le Cléac`H ,&nbsp;Jonathan D. Turner ,&nbsp;Archibold Mposhi","doi":"10.1016/j.neubiorev.2024.105785","DOIUrl":"10.1016/j.neubiorev.2024.105785","url":null,"abstract":"<div><p>Exposure to different environmental factors, social and socioeconomic factors promotes development of the early-life adversity (ELA) phenotype. The persistence of this phenotype across generations is an interesting phenomenon that remains unexplored. Of late many studies have focused on disease-associated outcomes of ELA following exposure during childhood but the persistence of epigenetic imprints transmitted by ELA exposed parents to their offspring remains poorly described. It is possible that both parents are able to transmit ELA-associated genetic imprints to their offspring via transgenerational inheritance mechanisms. Here, we highlight the role of the mother and father in the biological process of conception, from epigenetic reprogramming cycles to later environmental exposures. We explain some of the known determinants of ELA (pollution, socioeconomic challenges, infections, etc.) and their disease-associated outcomes. Finally, we highlight the role of epigenetics, mitochondria and ncRNAs as mechanisms mediating transgenerational inheritance. Whether these transgenerational inheritance mechanisms occur in the human context remains unclear but there is a large body of suggestive evidence in non-human models that points out to its existence.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002549/pdfft?md5=57e08b55ba3f07a0c2e8e1d973f16d32&pid=1-s2.0-S0149763424002549-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences between autistic and non-autistic individuals in audiovisual speech integration: A systematic review and meta-analysis","authors":"","doi":"10.1016/j.neubiorev.2024.105787","DOIUrl":"10.1016/j.neubiorev.2024.105787","url":null,"abstract":"<div><p>Research has indicated unique challenges in audiovisual integration of speech among autistic individuals, although methodological differences have led to divergent findings. We conducted a systematic literature search to identify studies that measured audiovisual speech integration among both autistic and non-autistic individuals. Across the 18 identified studies (combined N = 952), autistic individuals showed impaired audiovisual integration compared to their non-autistic peers (<em>g</em> = 0.69, 95 % CI [0.53, 0.85], <em>p</em> &lt;.001). This difference was not found to be influenced by participants’ mean ages, studies’ sample sizes, risk-of-bias scores, or paradigms employed. However, a subgroup analysis suggested that child studies may show larger between-group differences than adult ones. The prevailing pattern of impaired audiovisual speech integration in autism may have cascading effects on communicative and social behavior. However, small samples and inconsistency in designs/analyses translated into considerable heterogeneity in findings and opacity regarding the influence of underlying unisensory and attentional factors. We recommend three key directions for future research: larger samples, more research with adults, and standardization of methodology and analytical approaches.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002562/pdfft?md5=f2d6818c3f642aeb8811117f233b04db&pid=1-s2.0-S0149763424002562-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioural, autonomic, and neural responsivity in depersonalisation-derealisation disorder: A systematic review of experimental evidence","authors":"L.S. Merritt Millman ,&nbsp;Xi Huang ,&nbsp;Sorawit Wainipitapong ,&nbsp;Nick Medford ,&nbsp;Susannah Pick","doi":"10.1016/j.neubiorev.2024.105783","DOIUrl":"10.1016/j.neubiorev.2024.105783","url":null,"abstract":"<div><p>Depersonalisation-derealisation disorder (DDD) is characterised by distressing experiences of separation from oneself and/or one’s surroundings, potentially resulting from alterations in affective, cognitive, and physiological functions. This systematic review aimed to synthesise current experimental evidence of relevance to proposed mechanisms underlying DDD, to appraise existing theoretical models, and to inform future research and theoretical developments. Studies were included if they tested explicit hypotheses in DDD samples, with experimental manipulations of at least one independent variable, alongside behavioural, subjective, neurological, affective and/or physiological dependent variables. Some evidence for diminished subjective responsivity to aversive images and sounds, and hyperactivation in neurocircuits associated with emotional regulation when viewing aversive images emerged, corroborating neurobiological models of DDD. Inconsistencies were present regarding behavioural and autonomic responsivity to facial expressions, emotional memory, and self-referential processing. Common confounds included small sample sizes, medication, and comorbidities. Alterations in affective reactivity and regulation appear to be present in DDD; however, further research employing more rigorous research designs is required to provide stronger evidence for these possible mechanisms.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002525/pdfft?md5=d38b30ae3a0ba72dad612b4d792ca167&pid=1-s2.0-S0149763424002525-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive and brain morphological deviations in middle-to-old aged autistic adults: A systematic review and meta-analysis","authors":"Jingying Wang ,&nbsp;Danielle Christensen ,&nbsp;Stephen A. Coombes ,&nbsp;Zheng Wang","doi":"10.1016/j.neubiorev.2024.105782","DOIUrl":"10.1016/j.neubiorev.2024.105782","url":null,"abstract":"<div><p>Cognitive challenges and brain structure <strong>variations</strong> are common in autism spectrum disorder (ASD) but are rarely explored in middle-to-old aged autistic adults. Cognitive deficits that overlap between young autistic individuals and elderlies with dementia raise an important question: does compromised cognitive ability and brain structure during early development drive autistic adults to be more vulnerable to pathological aging conditions, or does it protect them from further decline? To answer this question, we have synthesized current theoretical models of aging in ASD and conducted a systematic literature review (<strong>Jan 1, 1980 - Feb 29, 2024</strong>) and meta-analysis to summarize empirical studies on cognitive and brain <strong>deviations</strong> in middle-to-old aged autistic adults. We explored findings that support different aging theories in ASD and addressed study limitations and future directions. This review sheds light on the poorly understood <em>consequences of aging</em> question raised by the autism community to pave the way for future studies to identify sensitive and reliable measures that best predict the onset, progression, and prognosis of pathological aging in ASD.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002513/pdfft?md5=6f6670b67eafea319f5bc5d47a7d282f&pid=1-s2.0-S0149763424002513-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional brain networks associated with the urge for action: Implications for pathological urge","authors":"Jade-Jocelyne Zouki ,&nbsp;Valsamma Eapen ,&nbsp;Daryl Efron ,&nbsp;Amanda Maxwell ,&nbsp;Daniel T. Corp ,&nbsp;Timothy J. Silk","doi":"10.1016/j.neubiorev.2024.105779","DOIUrl":"10.1016/j.neubiorev.2024.105779","url":null,"abstract":"<div><p>Tics in Tourette syndrome (TS) are often preceded by sensory urges that drive the motor and vocal symptoms. Many everyday physiological behaviors are associated with sensory phenomena experienced as an urge for action, which may provide insight into the neural correlates of this pathological urge to tic that remains elusive. This study aimed to identify a brain network common to distinct physiological behaviors in healthy individuals, and in turn, examine whether this network converges with a network we previously localized in TS, using novel ‘coordinate network mapping’ methods. Systematic searches were conducted to identify functional neuroimaging studies reporting correlates of the urge to micturate, swallow, blink, or cough. Using activation likelihood estimation meta-analysis, we identified an ‘urge network’ common to these physiological behaviors, involving the bilateral insula/claustrum/inferior frontal gyrus/supplementary motor area, mid-/anterior- cingulate cortex (ACC), right postcentral gyrus, and left thalamus/precentral gyrus. Similarity between the urge and TS networks was identified in the bilateral insula, ACC, and left thalamus/claustrum. The potential role of the insula/ACC as nodes in the network for bodily representations of the urge to tic are discussed.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002483/pdfft?md5=d8ff2ab7cdc4a71e2d01c4cf85b60e52&pid=1-s2.0-S0149763424002483-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional connectivity development in the prenatal and neonatal stages measured by functional magnetic resonance imaging: A systematic review","authors":"Jérémi Desrosiers ,&nbsp;Laura Caron-Desrochers ,&nbsp;Andréanne René ,&nbsp;Isabelle Gaudet ,&nbsp;Alix Pincivy ,&nbsp;Natacha Paquette ,&nbsp;Anne Gallagher","doi":"10.1016/j.neubiorev.2024.105778","DOIUrl":"10.1016/j.neubiorev.2024.105778","url":null,"abstract":"<div><p>The prenatal and neonatal periods are two of the most important developmental stages of the human brain. It is therefore crucial to understand normal brain development and how early connections are established during these periods, in order to advance the state of knowledge on altered brain development and eventually identify early brain markers of neurodevelopmental disorders and diseases. In this systematic review (Prospero ID: CRD42024511365), we compiled resting state functional magnetic resonance imaging (fMRI) studies in healthy fetuses and neonates, in order to outline the main characteristics of typical development of the functional brain connectivity during the prenatal and neonatal periods. A systematic search of five databases identified a total of 12 573 articles. Of those, 28 articles met pre-established selection criteria based determined by the authors after surveying and compiling the major limitations reported within the literature. Inclusion criteria were: (1) resting state studies; (2) presentation of original results; (3) use of fMRI with minimum one Tesla; (4) a population ranging from 20 weeks of GA to term birth (around 37–42 weeks of PMA); (5) singleton pregnancy with normal development (absence of any complications known to alter brain development). Exclusion criteria were: (1) preterm studies; (2) post-mortem studies; (3) clinical or pathological studies; (4) twin studies; (5) papers with a sole focus on methodology (i.e. focused on tool and analysis development); (6) volumetric studies; (7) activation map studies; (8) cortical analysis studies; (9) conference papers. A risk of bias assessment was also done to evaluate each article’s methodological rigor. 1877 participants were included across all the reviewed articles. Results consistently revealed a developmental gradient of increasing functional brain connectivity from posterior to anterior regions and from proximal-to-distal regions. A decrease in local small-world organization shortly after birth was also observed; small-world characteristics were present in fetuses and newborns, but appeared weaker in the latter group. Also, the posterior-to-anterior gradient could be associated with earlier development of the sensorimotor networks in the posterior regions while more complex higher-order networks (e.g. attention-related) mature later in the anterior regions. The main limitations of this systematic review stem from the inherent limitations of functional imaging in fetuses, mainly: unevenly distributed populations and limited sample sizes; fetal movements in the womb and other imaging obstacles; and a large voxel resolution when imaging a small brain. Another limitation specific to this review is the relatively small number of included articles compared to very a large search result, which may have led to relevant articles having been overlooked.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002471/pdfft?md5=23e0f9059f6f11eea669e369ebee31cb&pid=1-s2.0-S0149763424002471-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141473111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sense of agency in schizophrenia: A reconciliation of conflicting findings through a theory-driven literature review","authors":"Ileana Rossetti ,&nbsp;Marika Mariano ,&nbsp;Angelo Maravita ,&nbsp;Eraldo Paulesu ,&nbsp;Laura Zapparoli","doi":"10.1016/j.neubiorev.2024.105781","DOIUrl":"10.1016/j.neubiorev.2024.105781","url":null,"abstract":"<div><p>The sense of agency is the experience of being the author of self-generated actions and their outcomes. Both clinical manifestations and experimental evidence suggest that the agency experience and the mechanisms underlying agency attribution may be dysfunctional in schizophrenia. Yet, studies investigating the sense of agency in these patients show seemingly conflicting results: some indicated under-attribution of self-agency (coherently with certain positive symptoms), while others suggested over-attribution of self-agency. In this review, we assess whether recent theoretical frameworks can reconcile these <em>divergent</em> results. We examine whether the identification of agency abnormalities in schizophrenia might depend on the measure of self-agency considered (depending on the specific task requirements) and the available agency-related cues. We conclude that all these aspects are relevant to predict and characterize the type of agency misattribution that schizophrenia patients might show. We argue that one particular model, based on the predictive coding theory, can reconcile the interpretation of the multifarious phenomenology of agency manifestations in schizophrenia, paving the way for testing agency disorders in novel ways.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002501/pdfft?md5=ba407ab38b24131c54286f24035b92fb&pid=1-s2.0-S0149763424002501-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the right hemisphere retain functional characteristics typical of the emotional adaptive system? An evolutionary approach to the problem of brain asymmetries","authors":"Guido Gainotti","doi":"10.1016/j.neubiorev.2024.105777","DOIUrl":"10.1016/j.neubiorev.2024.105777","url":null,"abstract":"<div><p>The right and left hemispheres host two complementary adaptive systems with a right-sided prevalence of automatic and unconscious processing modes, typical of the ‘emotional system’, and a left-sided prevalence of propositional and conscious processing modes typical of the ‘cognitive system’ The principal right hemispheric syndromes (and the functioning modes typical of this hemisphere) are, indeed, characterized by automatic and unconscious processing modalities. Thus, the unilateral neglect syndrome discloses a defective automatic (and spared intentional) spatial orienting of attention; face and voice recognition disorders are due to disruption of mechanisms that automatically generate familiarity feelings and anosognosia seems due to the unconscious loss of personal significance attributed by the patient to the pathological event. Since emotions were the only adaptive system existing before the development of language (which is provided of a strong capacity to develop and shape cognition), the persistence in the right hemisphere of mechanisms typical of the emotional system strongly supports an evolutionary model of brain laterality. (160 words)</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatments in the pipeline for attention-deficit/hyperactivity disorder (ADHD) in adults","authors":"Guilherme Fusetto Veronesi ,&nbsp;Alessandra Gabellone ,&nbsp;Anneka Tomlinson ,&nbsp;Marco Solmi ,&nbsp;Christoph U. Correll ,&nbsp;Samuele Cortese","doi":"10.1016/j.neubiorev.2024.105774","DOIUrl":"10.1016/j.neubiorev.2024.105774","url":null,"abstract":"<div><p>To provide an overview of treatments in the pipeline for adults with attention-deficit/hyperactivity disorder (ADHD), we searched <span>https://clinicaltrials.gov/and</span><svg><path></path></svg> and <span>https://www.clinicaltrialsregister.eu/</span><svg><path></path></svg> from 01/01/2010–10/18/2023 for ongoing or completed phase 2 or 3 randomised controlled trials (RCTs), assessing pharmacological or non-pharmacological interventions for adults with ADHD with no current regulatory approval. We found 90 eligible RCTs. Of these, 24 (27 %) reported results with statistical analysis for primary efficacy endpoints. While several pharmacological and non-pharmacological interventions had evidence of superiority compared to the control condition from a single RCT, centanafadine (norepinephrine, dopamine, and serotonin re-uptake inhibitor) was the only treatment with evidence of efficacy on ADHD core symptoms (small effect size=0.28–0.40) replicated in at least one additional RCT, alongside reasonable tolerability. Overall, the body of ongoing RCTs in adults with ADHD is insufficient, without any intervention on the horizon to match the efficacy of stimulant treatment or atomoxetine and with better tolerability profile. Additional effective and well tolerated treatments for adults with ADHD require development and testing.</p></div>","PeriodicalId":56105,"journal":{"name":"Neuroscience and Biobehavioral Reviews","volume":null,"pages":null},"PeriodicalIF":7.5,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0149763424002434/pdfft?md5=2ce6261be6ed1977838973ac74491cde&pid=1-s2.0-S0149763424002434-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}