Science Progress最新文献

{"title":"miRNA profile in pancreatic neuroendocrine tumors: Preliminary results.","authors":"Oana A Ciobanu, Vlad Herlea, Elena Milanesi, Maria Dobre, Simona Fica","doi":"10.1177/00368504251326864","DOIUrl":"10.1177/00368504251326864","url":null,"abstract":"<p><strong>Objective: </strong>Our understanding of the pathophysiology of pancreatic neuroendocrine tumors (PanNETs) remains incomplete, largely due to their historically underestimated incidence and the perception of these tumors as rare and slow-growing cancers. Additionally, conventional reliance on histological examination alone is gradually being supplemented by the exploration and introduction of molecular biomarkers, such as microRNAs (miRNAs). As miRNAs modulate the expression of multiple genes and pathways involved in the tumorigenesis of PanNETs, these biomarkers hold considerable promise for diagnosis and prognosis applications. In this study, we aimed to identify miRNAs as tissue markers associated with the diagnosis of PanNETs.</p><p><strong>Methods: </strong>We conducted a case-control study including: 7 PanNETs and 19 nontumoral pancreatic tissues obtained from Romanian patients. The samples underwent miRNA profiling via quantitative RT-PCR to assess the expression of 84 miRNAs. Our results were compared with those obtained by reanalyzing a public dataset. Furthermore, we structured our miRNA expression data according to their targeted mRNAs and their roles in signaling pathways.</p><p><strong>Results: </strong>Fourteen miRNAs (miR-1, miR-133a-3p, miR-210-3p, miR-7-5p, miR-10a-5p, miR-92b-3p, miR-132-3p, miR-221-3p, miR-29b-3p, miR-107, miR-103a-3p, let-7b-5p, miR-148a-3p, and miR-202-3p) were identified as differentially expressed by comparing PanNETs with pancreatic nontumoral tissues, with six miRNAs (miR-7-5p, miR-92b-3p, miR-29b-3p, miR-107, miR-103a-3p, and miR-148a-3p) also found in the public dataset analyzed. Bioinformatic analysis revealed that the 14 identified miRNAs target 17 genes. Reanalyzing two public gene expression datasets, five of these genes have been found differentially expressed in PanNET compared to controls.</p><p><strong>Conclusions: </strong>Our preliminary results, albeit limited by a small sample size, highlighted a specific miRNA expression pattern able to distinguish tumoral from normal pancreatic tissue. The diagnostic performance of these miRNAs, matching with circulating miRNAs and validated in more homogeneous and large cohorts, could represent a starting point for improving the diagnostic accuracy of PanNETs.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251326864"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid dual-area power grid frequency fluctuation effective control utilizing a maiden combination of MOA-based 1 + PIID and PD^μF^λ controllers.","authors":"Kareem M AboRas, Ahmed Ma Sedik, Muhammad R Hammad","doi":"10.1177/00368504251330521","DOIUrl":"10.1177/00368504251330521","url":null,"abstract":"<p><p>Current power networks face considerable issues due to a continuous decrease in inertia and increased sensitivity to load/generation fluctuations. The main cause of these problems is the enhanced penetration capabilities of renewable energy sources. An unbalanced load with high power output greatly affects the frequency behavior of electrical grids. Several load-frequency control mechanisms are commonly employed to tackle these problems. Accordingly, the purpose of this work is to present a novel optimal load frequency control methodology for dual-area-linked power systems that contain a variety of conventional (i.e. thermal generator) and renewable (i.e. solar photovoltaic plant) power sources. A revolutionary hybrid regulator, the one plus proportional integral double-integral derivative with a proportional fractional derivative with fractional filter (1 + PIID-PD^μF^λ), has been designed. Its goal is to lessen frequency drifts brought on by any known load disturbance. The optimal gains of the 1 + PIID-PD^μF^λ controller are finely adjusted using the mother optimization algorithm, an up-to-date population-based metaheuristic optimization technique that simulates the procedure of birthing and growth. The mother optimization algorithm has demonstrated its superior performance compared to other brand-new optimization methods, including tuna swarm optimization and sea horse optimization. The effectiveness of the proposed mother optimization algorithm-based 1 + PIID-PD^μF^λ regulator is assessed by comparing its performance with other cascaded regulators in existing literature, such as TIDF-PID^μD, FOPI-PIDA, and PID-TID, which stand for tilt integral derivative with filter-proportional integral derivative fractional derivative with filter, proportional integral-proportional integral derivative acceleration, and proportional integral derivative-tilted integral derivative, respectively. Various scenarios involving fluctuations in load (step, multi-step, and random), solar radiation changes, and system parameter modifications are used to demonstrate the controller's effectiveness in handling disturbances. The simulation results, presented using MATLAB/SIMULINK, show that the proposed controller outperforms other existing controllers in terms of its dynamic response to system disturbances, namely it achieved a substantial reduction in frequency overshoot (94.66%, 48.49%, 68.75%), undershoot (94.66%, 26.75%, 67.25%), and settling time (78.57%, 90.81%, 75.0%) as measured by the frequency deviation in Area 1, respectively. Similar improvements were observed in frequency deviation in Area 2 and deviation in power exchange between system areas.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251330521"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe phlebitis and cutaneous necrosis following peripheral administration of high-concentration potassium chloride: A case report and vascular access management implications.","authors":"Fang Li, Ting Wang, Ling Wang, Siyang Zhao, Yuanyuan Zhang, Yuetong Ren, Hui Li, Hong Jiang","doi":"10.1177/00368504251314081","DOIUrl":"10.1177/00368504251314081","url":null,"abstract":"<p><p>Electrolyte imbalance management is crucial in diverse clinical scenarios, with intravenous potassium repletion often required. High-concentration infusions can pose severe complications if extravasation occurs, leading to phlebitis, local tissue damage, or in severe cases, cutaneous necrosis. This risk is elevated in geriatric patients due to factors like reduced tissue elasticity and sensitivity. We report a case of phlebitis and skin necrosis in an elderly woman after peripheral KCl infusion (6% [800 mmol/L]). A woman in her early 70 s presented with obstructive jaundice and critically low potassium levels. A peripheral intravenous administration of 6% KCl was initiated to rectify hypokalemia. Due to superficial venous site selection and the patient's reduced sensitivity, phlebitis developed unnoticed, leading to cutaneous necrosis. Management involved medication discontinuation, cannula removal, application of a magnesium sulfate dressing, limb elevation, and a hydrogel dressing. Despite initial necrosis, wound debridement, ongoing dressings, and moderate hand exercises led to a complete wound resolution. This case underscores the importance of careful selection and monitoring of infusion sites during administration of irritant solutions like concentrated KCl, particularly in geriatric patients. Patient-specific factors, pharmacological implications, and the necessity for adequate vascular assessment are emphasized. Further, the case highlights the necessity for prompt and multifaceted management strategies to handle complications, including patient and caregiver education, careful wound management, and proactive nursing care. The event underscores the need for established protocols regarding the administration of high-risk drugs to prevent severe sequelae.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251314081"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11752399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sinonasal extramedullary plasmacytoma: A case report and review of the literature.","authors":"Desderius Chussi, Kenneth Mlay, Ezekiel G Karuga, Elifaraja Naman, Philbert Mtenga, Peter Shija, Alex Mremi","doi":"10.1177/00368504241312434","DOIUrl":"10.1177/00368504241312434","url":null,"abstract":"<p><p>Primary solitary extramedullary plasmacytoma is a malignant neoplasm characterized by the monoclonal proliferation of plasma cells outside the bone marrow. The tumor rarely occurs in the sinonasal tract, accounting for about 4% of all non-epithelial sinonasal tumors. Herein, the authors describe a rare case of sinonasal extramedullary plasmacytoma in a 33-year-old man who presented with a 3-month history of progressively increasing nasal mass, causing obstruction. A CT scan showed a soft tissue mass measuring 5*8*3 cm in the right and left nasal cavities, obstructing the nasal airway. The mass extended to the right maxillary sinus. Histopathology and immunohistochemical tests confirmed it to be plasmacytoma. Lymphomas with prominent plasmacytic differentiation and multiple myeloma workups were negative. The patient initially refused treatment. After counseling, the patient consented to undergo surgery and later radiotherapy treatment. At one-year follow-up, the patient is disease-free with no signs of recurrence. Plasmacytomas are either medullary or extramedullary neoplasms. The latter are extremely rare tumors, more commonly presenting in the submucosal tissue of the upper respiratory tract. A mass or swelling causing nasal or pharyngeal symptoms is by far the most common presentation of this entity in the head and neck region. Because these lesions are radiosensitive, radiotherapy is a recommended treatment approach. Further studies are needed to better understand the prognosis and effective treatment regimens.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504241312434"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remarkable results of energy consumption and CO₂ emissions for gasoline and electric powered vehicle.","authors":"Tugba Tetik, Yasin Karagoz","doi":"10.1177/00368504241305897","DOIUrl":"https://doi.org/10.1177/00368504241305897","url":null,"abstract":"<p><p>Increasing concerns about climate change and efforts on reducing reliance on fossil fuels have led to research on electric vehicles for sustainable solutions to increasing energy demands. This study comprehensively analyzes the impact of power plant emissions on the adoption of electric vehicles in relation to air pollution. The main pollutants emitted by power plants and the potential change in emissions with the deployment of electric vehicles are assessed. Energy consumption of the vehicles was calculated. A gasoline-powered and an electric vehicle are modelled in MATLAB Simulink software. The theoretical model results of the main pollutants are compared with the power plant emissions to analyze the effect on major pollutants. This investigation aims to identify the potential CO₂ emission and power requirement by transitioning to electric vehicles. Results show that energy consumption and CO₂ emissions can be 111% and 82% higher than GPVs depending on the electricity generation technologies.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504241305897"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation study between magnetic resonance imaging-quantitated cardiac iron deposition and left ventricular function in patients with β-thalassemia major in China.","authors":"Shuai Peng, Fengming Xu, Guangxin Yang, Yanyan Zhang, Qin Tang, Rongrong Liu, Peng Peng","doi":"10.1177/00368504251318196","DOIUrl":"10.1177/00368504251318196","url":null,"abstract":"<p><strong>Objective: </strong>To explore the correlation between cardiac iron deposition and left ventricular function indicators, such as left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction, and to evaluate the accuracy of predicting patients with cardiac iron deposition by using left ventricular ejection fraction as an index.</p><p><strong>Methods: </strong>This quantitative cross-sectional study involved one hundred and fifty transfusion-dependent patients with β-thalassemia major who were evaluated by magnetic resonance imaging to obtain <i>T</i>₂* values, left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction. The relationship between cardiac <i>R</i>₂* values and left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction was analyzed.</p><p><strong>Results: </strong>Out of the 150 patients, cardiac iron overload was not observed for 92 patients, 42 patients exhibited mild to moderate cardiac iron overload, and 16 patients were severe cardiac iron overloaded. A linear correlation was not observed between the cardiac <i>R</i>₂* values and left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction (<i>P</i> > 0.05). For the left ventricular ejection fraction index, the sensibility, specificity, positive predictive value, negative predictive value, and the agreement rate were 83.3%, 63.2%, 8.6%, 98.9%, and 64.0%, respectively; also, the area under the receiver operating characteristic curve was 0.348.</p><p><strong>Conclusions: </strong>A linear correlation was not observed between cardiac <i>R</i>₂* values and left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction in patients with β-thalassemia major. Therefore, using left ventricular ejection fraction as an indirect index to predict cardiac iron deposition may be not reliable in clinical practice.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251318196"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative technique with enriched movement directions to plan the trajectory for an autonomous Mobile robot.","authors":"Souhail Dhouib","doi":"10.1177/00368504251321714","DOIUrl":"10.1177/00368504251321714","url":null,"abstract":"<p><p>This paper presents a deep analysis of a novel method entitled Dhouib-Matrix-SPP-24 (DM-SPP-24) and its application to rapidly generate the shortest trajectory for an autonomous mobile robot. For this problem, the environment is represented by a grid map where several obstacles are exposed with static positions and the main objective is to plan the shortest trajectory for an autonomous mobile robot from the current to the target positions with obstacles free-collisions. This study introduces an in-depth exploration of the twenty-four movement directions of the DM-SPP-24 method, an application on six grid maps and a comparison to several recent metaheuristics taken from the literature (such as the Improved Ant Colony Algorithm, the enhanced Ant Colony Optimization with Gaussian Sampling, the Particle Swarm Optimization, the Genetic Algorithm and other methods). Indeed, a new method namely DM-SPP-24 is introduced and this study notes an improvement in the quality and the rapidity of the generated solution by DM-SPP-24 versus the solution produced by the recent published metaheuristics in the literature. This work serves as a valuable resource for robotics and path planning viewing that it introduces a very fast and accurate method (DM-SPP-24) to plan the trajectory of an autonomous mobile robot.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251321714"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuro-fuzzy scheme plus optimal PI control for controlling DC-DC converters.","authors":"Muhammed Süleyman, Tarık Veli Mumcu","doi":"10.1177/00368504241288790","DOIUrl":"10.1177/00368504241288790","url":null,"abstract":"<p><p>The importance of solar systems as a renewable source has recently captured significant efforts from governments around the world to reduce their dependency on fossil fuels. Improving the efficiency of these systems, in general, is an important topic. Specifically, enhancing the control method used for controlling the DC-DC converter occupies a significant place in the efforts dedicated to increasing the efficiency of the solar system. The nonlinearity of such systems might deteriorate the performance of traditional controllers, such as PIDs. Therefore, this paper suggests a new scheme which consists of a PI controller and a neuro-fuzzy controller in a cascade manner. Particle swarm optimization is used for optimally designing the parameters of the PI controller for improving the system's dynamic and steady-state responses. Also, the proposed PI controller has only two tuning parameters which significantly reduce the design time. The system inputs of the proposed fuzzy controller are the power and the current changes, and its output is the duty cycle which directly affects the desired output voltage. On the other hand, the input of the PI controller is the error signal between the desired voltage and the output voltage of the DC-DC converter which forms the controlled variable. The main contribution of the paper is to enhance the efficiency of the system via connecting the optimal PI and neuro-fuzzy controller, which can store human experiences. Different scenarios are used to test the proposed controller and obtain optimal maximum power point tracking under different weather conditions. Results show that the proposed controller significantly improves the efficiency percentage of the DC-DC converter relative to the neuro-fuzzy controller alone by at least 15%. Also, the integral square error index indicates the proposed method has small tracking errors either for the setpoint tracking or disturbance rejection.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504241288790"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy and time efficiency of an automated commercial audiometer in the evaluation of hearing in quiet and noisy environments.","authors":"Ying Yi, Xian-Ren Wang, Qin Xiong, Guan-Xia Xiong","doi":"10.1177/00368504251324348","DOIUrl":"10.1177/00368504251324348","url":null,"abstract":"<p><strong>Introduction: </strong>In this study, we sought to validate the effectiveness of an automated audiometry system in quiet (AA) and noisy environments (AA-N) by comparing the air pure-tone thresholds obtained by AA to those obtained by traditional manual audiometry (MA).</p><p><strong>Methods: </strong>In this cross-sectional study, 150 participants with or without hearing loss were tested (age: 11-84 years; female: 57.3%). Air conduction thresholds were assessed by MA, AA, and AA-N in a quiet or noisy sound booth.</p><p><strong>Results: </strong>In participants without hearing loss, 94.5% and 96% of the threshold comparisons differed between MA versus AA and AA versus AA-N within 10 dB HL or less. In participants with hearing loss, there was no statistically significant difference between the three testing conditions at any frequency (<i>p</i> > 0.05). The hearing threshold difference in the poor hearing ear in participants with a bilateral difference ≥40 dB HL was -15 and +15 dB HL; however, this difference was not statistically significant when excluding participants with tinnitus.</p><p><strong>Conclusions: </strong>Automatic audiometry can accurately estimate hearing thresholds and screen for hearing loss even in noisy environments. Nevertheless, the algorithm must be corrected when patients experience tinnitus.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251324348"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Middle meningeal artery embolization for recurrent subdural hematoma in an extra-intracranial anastomosis patient on anticoagulant medication: A case report.","authors":"Franziska A Schmidt, Christian F Freyschlag, Astrid E Grams, Claudius Thomé","doi":"10.1177/00368504241271730","DOIUrl":"10.1177/00368504241271730","url":null,"abstract":"<p><p>Symptomatic chronic subdural hematoma (cSDH) is amongst the most frequent neurological diseases with an upward trend due to an aging society and development in the field of anticoagulation therapies. Lately, subgaleal drainages and middle meningeal artery (MMA) embolization have been introduced to the standard armamentarium as treatment options for cSDH patients. Vascular anomalies, such as internal carotid artery (ICA) occlusion with spontaneous extra-intracranial anastomoses, usually lead to forfeiting embolization treatment from patients. This report presents a case of a 67-year-old male with a repeated recurrence of cSDH in conjunction with a history of middle cerebral artery territory stroke and consecutive platelet inhibition therapy. The patient was initially treated with a burr hole plus subgaleal and subdural drainage upon revision surgery. Due to repeated recurrence, MMA embolization was considered, even though an extra-intracranial anastomosis was present on angiography. The patient was deemed to be fully recovered three months after intervention and no further intervention was needed. We can conclude that MMA embolization is a feasible option also in patients with recurrent cSDH after territorial infarction secondary to ICA occlusion with present extra-intracranial anastomoses.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504241271730"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748381/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}