Science Progress最新文献

{"title":"Development and external validation of Global Leadership Initiative on Malnutrition-dictated nomograms predicting long-term mortality in hospitalized patients with cirrhosis.","authors":"Qing Liu, Yumei He, Fang Yang, Gaoyue Guo, Wanting Yang, Liping Wu, Chao Sun","doi":"10.1177/00368504251320157","DOIUrl":"10.1177/00368504251320157","url":null,"abstract":"<p><strong>Objectives: </strong>Global Leadership Initiative on Malnutrition (GLIM) criteria have gradually accounted for the mainstay evaluating nutritional status. We sought to establish GLIM-dictated nomograms with other prognostic factors influencing long-term mortality and externally validate their predictive performance in decompensated cirrhosis.</p><p><strong>Methods: </strong>The derivation cohort comprised 301 patients presenting with cirrhosis-associated acute insults, while the validation cohort encompassed 101 subjects from another tertiary hospital. Two nomograms were constructed to predict the 1-year all-cause mortality by integrating the GLIM criteria. The study population was stratified into low-, moderate- and high-risk mortality groups according to aforesaid proposed models.</p><p><strong>Results: </strong>Adjusting Child-Turcotte-Pugh classification (Nomo#1) or Model for End-stage Liver Disease-Sodium score (Nomo#2) separately, the GLIM criteria were independently associated with 1-year mortality in the multivariate Cox regression analysis (Nomo#1 hazard ratio (HR) = 3.139, <i>p</i> < 0.001; Nomo#2 HR = 3.456, <i>p</i> < 0.001). The C-index and time AUC for Nomo#1 and Nomo#2 performed significantly better than those of the GLIM criteria or conventional scoring systems alone. The survival rate of the low-risk group was significantly higher than those of the moderate- or high-risk groups (Nomo#1: 95% <i>vs</i> 65.8% <i>vs</i> 33.3%, <i>p</i> < 0.001; Nomo#2: 94.3% <i>vs</i> 64.5% <i>vs</i> 25%, <i>p</i> < 0.001). Furthermore, our proposed models exhibited moderate prediction accuracy and may identify malnourished patients with poor survival conditions in the external validation cohort.</p><p><strong>Conclusion: </strong>GLIM criteria-defined malnutrition negatively impacted long-term mortality in the context of decompensated cirrhosis. Our established nomograms may predict survival status with sufficient discriminatory ability, alongside good consistency and clinical benefits, supporting their effectiveness in daily practice.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251320157"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837080/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk assessment of existing buildings in tunnel construction based on an improved cumulative prospect theory method.","authors":"Lixin Chang, Norhaiza Nordin, Xinhua Gu, Ye Zhao","doi":"10.1177/00368504251320350","DOIUrl":"10.1177/00368504251320350","url":null,"abstract":"<p><p>As urbanization in China continues to rise, an increasing number of cities are constructing subway tunnels. However, due to the complexity and ambiguity of subway tunnel construction, there is a lack of precise methods to assess the impact of these constructions on surrounding buildings. Consequently, this study analyzes and summarizes past experiences and proposes the IVTSFS-CPT-EDAS model based on the CPT-EDAS evaluation method. This model establishes a risk assessment approach specifically for the impact of subway tunnel construction on existing buildings. The model's process was validated through a real-world case study, including a sensitivity analysis to verify its effectiveness and feasibility. The findings of this study indicate: (1) The IVTSFS-CPT-EDAS model can more comprehensively and delicately replicate the actual decision-making environment, enhancing the accuracy of the model. (2) The analysis of expert evaluations indicates that improper material and equipment configuration, inadequate excavation pressure control, and non-compliance of the stratum solubility coefficient with requirements are the primary risk factors affecting the building. (3) The advantages of the proposed model over other approaches and the accuracy enhancement of the assessment results due to the improvements in the evaluation method were demonstrated through sensitivity analysis and comparative evaluation. This research is expected to provide valuable insights for the scientific management of the impacts of subway tunnel construction on nearby structures.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251320350"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study on the molecular mechanism of cardiac protection of procarboxylpeptidase in MIRI rats based on the NLRP3 signaling pathway.","authors":"Luxiao He, Youfa Qin, Qiuping Lu, Ye Luo","doi":"10.1177/00368504251322085","DOIUrl":"10.1177/00368504251322085","url":null,"abstract":"<p><p>ObjectiveTo investigate the way in which prolylcarboxypeptidase (PRCP) protects against myocardial ischemia-reperfusion injury (MIRI) and the mechanisms that underlie it.MethodA surgical ligation of the coronary artery was adopted to establish a myocardial ischemia-reperfusion model in male SD rats. Thirty-six rats were randomly divided into six groups: Normal group, Sham group, MIRI model group, empty vector (MIRI + EZ.null) group, PRCP overexpression (MIRI + PRCP) group, and nicorandil (MIRI + Nic) group, with 6 rats in each group. The rats received an injection of PRCP's adeno-associated virus 9 (AAV9) through the tail vein 3 weeks prior to the modeling.ResultsCompared with the Normal and Sham groups, the expression levels of NOD-like receptor thermal protein domain-associated protein 3 (NLRP3), Caspase-1, IL-18, IL-1β, and GSDMD in the MIRI group and MIRI + EZ-null group were significantly increased (<i>P</i> < 0.05). Myocardial apoptosis index, myocardial infarction size, ejection fraction, and short axis shortening rate were significantly increased (<i>P</i> < 0.05). At the same time, PRCP and nicorandil therapy could reverse the damage effect caused by MIRI (<i>P</i> < 0.05).ConclusionPRCP can lessen MIRI and protect cardiac function in rats by inhibiting NLRP3/Capase-1/IL-18/IL-1β signaling pathway-mediated cell pyroptosis.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251322085"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hybrid dual-area power grid frequency fluctuation effective control utilizing a maiden combination of MOA-based 1 + PIID and PD^μF^λ controllers.","authors":"Kareem M AboRas, Ahmed Ma Sedik, Muhammad R Hammad","doi":"10.1177/00368504251330521","DOIUrl":"10.1177/00368504251330521","url":null,"abstract":"<p><p>Current power networks face considerable issues due to a continuous decrease in inertia and increased sensitivity to load/generation fluctuations. The main cause of these problems is the enhanced penetration capabilities of renewable energy sources. An unbalanced load with high power output greatly affects the frequency behavior of electrical grids. Several load-frequency control mechanisms are commonly employed to tackle these problems. Accordingly, the purpose of this work is to present a novel optimal load frequency control methodology for dual-area-linked power systems that contain a variety of conventional (i.e. thermal generator) and renewable (i.e. solar photovoltaic plant) power sources. A revolutionary hybrid regulator, the one plus proportional integral double-integral derivative with a proportional fractional derivative with fractional filter (1 + PIID-PD^μF^λ), has been designed. Its goal is to lessen frequency drifts brought on by any known load disturbance. The optimal gains of the 1 + PIID-PD^μF^λ controller are finely adjusted using the mother optimization algorithm, an up-to-date population-based metaheuristic optimization technique that simulates the procedure of birthing and growth. The mother optimization algorithm has demonstrated its superior performance compared to other brand-new optimization methods, including tuna swarm optimization and sea horse optimization. The effectiveness of the proposed mother optimization algorithm-based 1 + PIID-PD^μF^λ regulator is assessed by comparing its performance with other cascaded regulators in existing literature, such as TIDF-PID^μD, FOPI-PIDA, and PID-TID, which stand for tilt integral derivative with filter-proportional integral derivative fractional derivative with filter, proportional integral-proportional integral derivative acceleration, and proportional integral derivative-tilted integral derivative, respectively. Various scenarios involving fluctuations in load (step, multi-step, and random), solar radiation changes, and system parameter modifications are used to demonstrate the controller's effectiveness in handling disturbances. The simulation results, presented using MATLAB/SIMULINK, show that the proposed controller outperforms other existing controllers in terms of its dynamic response to system disturbances, namely it achieved a substantial reduction in frequency overshoot (94.66%, 48.49%, 68.75%), undershoot (94.66%, 26.75%, 67.25%), and settling time (78.57%, 90.81%, 75.0%) as measured by the frequency deviation in Area 1, respectively. Similar improvements were observed in frequency deviation in Area 2 and deviation in power exchange between system areas.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251330521"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"miRNA profile in pancreatic neuroendocrine tumors: Preliminary results.","authors":"Oana A Ciobanu, Vlad Herlea, Elena Milanesi, Maria Dobre, Simona Fica","doi":"10.1177/00368504251326864","DOIUrl":"10.1177/00368504251326864","url":null,"abstract":"<p><strong>Objective: </strong>Our understanding of the pathophysiology of pancreatic neuroendocrine tumors (PanNETs) remains incomplete, largely due to their historically underestimated incidence and the perception of these tumors as rare and slow-growing cancers. Additionally, conventional reliance on histological examination alone is gradually being supplemented by the exploration and introduction of molecular biomarkers, such as microRNAs (miRNAs). As miRNAs modulate the expression of multiple genes and pathways involved in the tumorigenesis of PanNETs, these biomarkers hold considerable promise for diagnosis and prognosis applications. In this study, we aimed to identify miRNAs as tissue markers associated with the diagnosis of PanNETs.</p><p><strong>Methods: </strong>We conducted a case-control study including: 7 PanNETs and 19 nontumoral pancreatic tissues obtained from Romanian patients. The samples underwent miRNA profiling via quantitative RT-PCR to assess the expression of 84 miRNAs. Our results were compared with those obtained by reanalyzing a public dataset. Furthermore, we structured our miRNA expression data according to their targeted mRNAs and their roles in signaling pathways.</p><p><strong>Results: </strong>Fourteen miRNAs (miR-1, miR-133a-3p, miR-210-3p, miR-7-5p, miR-10a-5p, miR-92b-3p, miR-132-3p, miR-221-3p, miR-29b-3p, miR-107, miR-103a-3p, let-7b-5p, miR-148a-3p, and miR-202-3p) were identified as differentially expressed by comparing PanNETs with pancreatic nontumoral tissues, with six miRNAs (miR-7-5p, miR-92b-3p, miR-29b-3p, miR-107, miR-103a-3p, and miR-148a-3p) also found in the public dataset analyzed. Bioinformatic analysis revealed that the 14 identified miRNAs target 17 genes. Reanalyzing two public gene expression datasets, five of these genes have been found differentially expressed in PanNET compared to controls.</p><p><strong>Conclusions: </strong>Our preliminary results, albeit limited by a small sample size, highlighted a specific miRNA expression pattern able to distinguish tumoral from normal pancreatic tissue. The diagnostic performance of these miRNAs, matching with circulating miRNAs and validated in more homogeneous and large cohorts, could represent a starting point for improving the diagnostic accuracy of PanNETs.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251326864"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe phlebitis and cutaneous necrosis following peripheral administration of high-concentration potassium chloride: A case report and vascular access management implications.","authors":"Fang Li, Ting Wang, Ling Wang, Siyang Zhao, Yuanyuan Zhang, Yuetong Ren, Hui Li, Hong Jiang","doi":"10.1177/00368504251314081","DOIUrl":"10.1177/00368504251314081","url":null,"abstract":"<p><p>Electrolyte imbalance management is crucial in diverse clinical scenarios, with intravenous potassium repletion often required. High-concentration infusions can pose severe complications if extravasation occurs, leading to phlebitis, local tissue damage, or in severe cases, cutaneous necrosis. This risk is elevated in geriatric patients due to factors like reduced tissue elasticity and sensitivity. We report a case of phlebitis and skin necrosis in an elderly woman after peripheral KCl infusion (6% [800 mmol/L]). A woman in her early 70 s presented with obstructive jaundice and critically low potassium levels. A peripheral intravenous administration of 6% KCl was initiated to rectify hypokalemia. Due to superficial venous site selection and the patient's reduced sensitivity, phlebitis developed unnoticed, leading to cutaneous necrosis. Management involved medication discontinuation, cannula removal, application of a magnesium sulfate dressing, limb elevation, and a hydrogel dressing. Despite initial necrosis, wound debridement, ongoing dressings, and moderate hand exercises led to a complete wound resolution. This case underscores the importance of careful selection and monitoring of infusion sites during administration of irritant solutions like concentrated KCl, particularly in geriatric patients. Patient-specific factors, pharmacological implications, and the necessity for adequate vascular assessment are emphasized. Further, the case highlights the necessity for prompt and multifaceted management strategies to handle complications, including patient and caregiver education, careful wound management, and proactive nursing care. The event underscores the need for established protocols regarding the administration of high-risk drugs to prevent severe sequelae.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251314081"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11752399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sinonasal extramedullary plasmacytoma: A case report and review of the literature.","authors":"Desderius Chussi, Kenneth Mlay, Ezekiel G Karuga, Elifaraja Naman, Philbert Mtenga, Peter Shija, Alex Mremi","doi":"10.1177/00368504241312434","DOIUrl":"10.1177/00368504241312434","url":null,"abstract":"<p><p>Primary solitary extramedullary plasmacytoma is a malignant neoplasm characterized by the monoclonal proliferation of plasma cells outside the bone marrow. The tumor rarely occurs in the sinonasal tract, accounting for about 4% of all non-epithelial sinonasal tumors. Herein, the authors describe a rare case of sinonasal extramedullary plasmacytoma in a 33-year-old man who presented with a 3-month history of progressively increasing nasal mass, causing obstruction. A CT scan showed a soft tissue mass measuring 5*8*3 cm in the right and left nasal cavities, obstructing the nasal airway. The mass extended to the right maxillary sinus. Histopathology and immunohistochemical tests confirmed it to be plasmacytoma. Lymphomas with prominent plasmacytic differentiation and multiple myeloma workups were negative. The patient initially refused treatment. After counseling, the patient consented to undergo surgery and later radiotherapy treatment. At one-year follow-up, the patient is disease-free with no signs of recurrence. Plasmacytomas are either medullary or extramedullary neoplasms. The latter are extremely rare tumors, more commonly presenting in the submucosal tissue of the upper respiratory tract. A mass or swelling causing nasal or pharyngeal symptoms is by far the most common presentation of this entity in the head and neck region. Because these lesions are radiosensitive, radiotherapy is a recommended treatment approach. Further studies are needed to better understand the prognosis and effective treatment regimens.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504241312434"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11736759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remarkable results of energy consumption and CO₂ emissions for gasoline and electric powered vehicle.","authors":"Tugba Tetik, Yasin Karagoz","doi":"10.1177/00368504241305897","DOIUrl":"https://doi.org/10.1177/00368504241305897","url":null,"abstract":"<p><p>Increasing concerns about climate change and efforts on reducing reliance on fossil fuels have led to research on electric vehicles for sustainable solutions to increasing energy demands. This study comprehensively analyzes the impact of power plant emissions on the adoption of electric vehicles in relation to air pollution. The main pollutants emitted by power plants and the potential change in emissions with the deployment of electric vehicles are assessed. Energy consumption of the vehicles was calculated. A gasoline-powered and an electric vehicle are modelled in MATLAB Simulink software. The theoretical model results of the main pollutants are compared with the power plant emissions to analyze the effect on major pollutants. This investigation aims to identify the potential CO₂ emission and power requirement by transitioning to electric vehicles. Results show that energy consumption and CO₂ emissions can be 111% and 82% higher than GPVs depending on the electricity generation technologies.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504241305897"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11705307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation study between magnetic resonance imaging-quantitated cardiac iron deposition and left ventricular function in patients with β-thalassemia major in China.","authors":"Shuai Peng, Fengming Xu, Guangxin Yang, Yanyan Zhang, Qin Tang, Rongrong Liu, Peng Peng","doi":"10.1177/00368504251318196","DOIUrl":"10.1177/00368504251318196","url":null,"abstract":"<p><strong>Objective: </strong>To explore the correlation between cardiac iron deposition and left ventricular function indicators, such as left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction, and to evaluate the accuracy of predicting patients with cardiac iron deposition by using left ventricular ejection fraction as an index.</p><p><strong>Methods: </strong>This quantitative cross-sectional study involved one hundred and fifty transfusion-dependent patients with β-thalassemia major who were evaluated by magnetic resonance imaging to obtain <i>T</i>₂* values, left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction. The relationship between cardiac <i>R</i>₂* values and left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction was analyzed.</p><p><strong>Results: </strong>Out of the 150 patients, cardiac iron overload was not observed for 92 patients, 42 patients exhibited mild to moderate cardiac iron overload, and 16 patients were severe cardiac iron overloaded. A linear correlation was not observed between the cardiac <i>R</i>₂* values and left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction (<i>P</i> > 0.05). For the left ventricular ejection fraction index, the sensibility, specificity, positive predictive value, negative predictive value, and the agreement rate were 83.3%, 63.2%, 8.6%, 98.9%, and 64.0%, respectively; also, the area under the receiver operating characteristic curve was 0.348.</p><p><strong>Conclusions: </strong>A linear correlation was not observed between cardiac <i>R</i>₂* values and left ventricular end-diastolic volume index, left ventricular end-systolic volume index, and left ventricular ejection fraction in patients with β-thalassemia major. Therefore, using left ventricular ejection fraction as an indirect index to predict cardiac iron deposition may be not reliable in clinical practice.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251318196"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative technique with enriched movement directions to plan the trajectory for an autonomous Mobile robot.","authors":"Souhail Dhouib","doi":"10.1177/00368504251321714","DOIUrl":"10.1177/00368504251321714","url":null,"abstract":"<p><p>This paper presents a deep analysis of a novel method entitled Dhouib-Matrix-SPP-24 (DM-SPP-24) and its application to rapidly generate the shortest trajectory for an autonomous mobile robot. For this problem, the environment is represented by a grid map where several obstacles are exposed with static positions and the main objective is to plan the shortest trajectory for an autonomous mobile robot from the current to the target positions with obstacles free-collisions. This study introduces an in-depth exploration of the twenty-four movement directions of the DM-SPP-24 method, an application on six grid maps and a comparison to several recent metaheuristics taken from the literature (such as the Improved Ant Colony Algorithm, the enhanced Ant Colony Optimization with Gaussian Sampling, the Particle Swarm Optimization, the Genetic Algorithm and other methods). Indeed, a new method namely DM-SPP-24 is introduced and this study notes an improvement in the quality and the rapidity of the generated solution by DM-SPP-24 versus the solution produced by the recent published metaheuristics in the literature. This work serves as a valuable resource for robotics and path planning viewing that it introduces a very fast and accurate method (DM-SPP-24) to plan the trajectory of an autonomous mobile robot.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 1","pages":"368504251321714"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}