Trends in Environmental Analytical Chemistry最新文献

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Chromatographic determination of pesticides in soil: Current trends in analysis and sample preparation 土壤中农药的色谱测定:分析和样品制备的最新趋势
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-09-01 DOI: 10.1016/j.teac.2022.e00174
Dina Orazbayeva, Aset Muratuly, Marat Bektassov, Aray Zhakupbekova, Bulat Kenessov
{"title":"Chromatographic determination of pesticides in soil: Current trends in analysis and sample preparation","authors":"Dina Orazbayeva,&nbsp;Aset Muratuly,&nbsp;Marat Bektassov,&nbsp;Aray Zhakupbekova,&nbsp;Bulat Kenessov","doi":"10.1016/j.teac.2022.e00174","DOIUrl":"10.1016/j.teac.2022.e00174","url":null,"abstract":"<div><p>Soil is a primary sink and reservoir for pesticides pollution and one of the priority objects in terms of pesticides safety guidelines. Pesticides’ analysis in soil is a field of research which is in constant development facing numerous challenges such as the increasing amount and variety of analytes and their combinations, as well as the increasing demand for faster, simpler, more accurate and multiresidue analysis. This review provides the summary of studies on pesticides analysis in soil based on chromatography-coupled methods published between 2015 and 2022. We discuss the shift toward faster, greener, and simpler alternatives to conventional techniques, application of sample preparation and detection methods to targeted and untargeted pesticide analysis, as well as the developments in stereoselective determination of chiral pesticides. The sample preparation methods such as solid-phase extraction, dispersive solid-phase extraction, and derived methods, as well as the recent trends and developments in chromatographic separation of pesticides are covered in this review. For sample preparation, the QuEChERS method is replacing other techniques and has proved to be efficient in both screening and accurate quantification in multiresidue analysis. Shift towards minimal sample preparation is supported by a wider application of highly sensitive and selective separation and detection systems such as LC-MS/MS. The features of different methods of sample preparation and detection are discussed with focus on optimal parameters, advantages, and drawbacks. The optimal parameters of sample preparation methods were summarized based on respective publications, which makes the review a useful tool for method development and further investigations.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"35 ","pages":"Article e00174"},"PeriodicalIF":11.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46560904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Molecularly imprinted polymers-based sensors for bisphenol-A: Recent developments and applications in environmental, food and biomedical analysis 基于分子印迹聚合物的双酚a传感器:在环境、食品和生物医学分析中的最新发展和应用
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-09-01 DOI: 10.1016/j.teac.2022.e00167
Eslam M. Hamed , Sam F.Y. Li
{"title":"Molecularly imprinted polymers-based sensors for bisphenol-A: Recent developments and applications in environmental, food and biomedical analysis","authors":"Eslam M. Hamed ,&nbsp;Sam F.Y. Li","doi":"10.1016/j.teac.2022.e00167","DOIUrl":"10.1016/j.teac.2022.e00167","url":null,"abstract":"<div><p><span>Bisphenol A (BPA) is a well-known endocrine-disrupting industrial compound that is found throughout many aspects of our daily life; from the water we drink and the food we eat to the babies’ bottles and children’s plastic toys. Chronic exposure to BPA may result in some severe medical issues which account for the great importance of its monitoring and removal from everyday products. The use of </span>molecularly imprinted polymers (MIPs) for that purpose has acquired a lot of traction in recent decades. MIPs are artificial antibodies with selective recognition cavities for specifically targeted substances. They are created using a variety of synthetic methods and employed in numerous types of sensors to be used in a wide range of applications. In this review, we focus on the different production methods of MIPs and the varied types of electrochemical and optical sensors that employed MIPs to detect and analyze BPA. Finally, the broad variety of applications of MIPs in environmental, foodstuff, and biological samples are thoroughly examined. Future expected trends and prospective developments are also assessed.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"35 ","pages":"Article e00167"},"PeriodicalIF":11.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"55178527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Mass spectrometric analysis for carboxylic acids as viable markers of petroleum hydrocarbon biodegradation 羧酸作为石油烃生物降解标志物的质谱分析
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-09-01 DOI: 10.1016/j.teac.2022.e00172
Kevin Iyere Ehiosun , Régis Grimaud , Ryszard Lobinski
{"title":"Mass spectrometric analysis for carboxylic acids as viable markers of petroleum hydrocarbon biodegradation","authors":"Kevin Iyere Ehiosun ,&nbsp;Régis Grimaud ,&nbsp;Ryszard Lobinski","doi":"10.1016/j.teac.2022.e00172","DOIUrl":"10.1016/j.teac.2022.e00172","url":null,"abstract":"<div><p>The characterization of metabolites, which are considered markers of bacterial degradation of hydrocarbons, is gaining in importance. Over the years, carboxylic acids have served as useful indicators of aerobic and anaerobic hydrocarbon biodegradation. This interest has been accompanied by the extensive and robust development of analytical methods for monitoring, untargeted identification, and specific and sensitive determination of carboxylic acids in complex matrices. This review discusses critically the state-of-the-art of mass spectrometry as a reliable analytical technique to identify and quantify carboxylic acid metabolites. Attention is paid to sample pre-treatment, selective group pre-concentration, and gas and liquid chromatography preceding mass spectrometry to alleviate matrix effects and ionization discrimination. Recent specific applications of mass spectrometry in monitoring carboxylic acids for assessing hydrocarbon biodegradation are reviewed. Presently, no single technique is sufficient for holistic profiling of carboxylic acids. The direct characterization of carboxylic acids by mass spectrometry is the ultimate goal but despite recent significant developments, challenges persist.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"35 ","pages":"Article e00172"},"PeriodicalIF":11.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45217871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Quaternary ammonium pesticides: A review of chromatography and non-chromatography methods for determination of pesticide residues in water samples 季铵农药:水样中农药残留量色谱法和非色谱法的综述
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-09-01 DOI: 10.1016/j.teac.2022.e00171
Ismael dos S. Belmonte, Tânia M. Pizzolato, Mariana R. Gama
{"title":"Quaternary ammonium pesticides: A review of chromatography and non-chromatography methods for determination of pesticide residues in water samples","authors":"Ismael dos S. Belmonte,&nbsp;Tânia M. Pizzolato,&nbsp;Mariana R. Gama","doi":"10.1016/j.teac.2022.e00171","DOIUrl":"10.1016/j.teac.2022.e00171","url":null,"abstract":"<div><p><span>The monitoring of pesticide residues in water sources is essential because of their increased worldwide demand in agriculture and their subsequent detection in waters. Pesticide residues in water matrices are traditionally determined by multiresidue methodologies based on chromatography coupled to mass spectrometry. However, for quaternary ammonium pesticide residues, as highly polar compounds, the chromatographic approach frequently fails, requiring modifications in the separation method, or even an alternative technique for analyte quantification. Therefore, to solve this analytical limitation for these residues, several authors proposed unusual methodologies, such as those based on spectroscopic or electroanalytical approaches. This review intends to offer an overview of the analysis of quaternary ammonium pesticide residues in different water sources, focusing on advances in sample preparation before chromatographic separations and alternative analytical techniques, such as spectroscopy and </span>electroanalytical methods.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"35 ","pages":"Article e00171"},"PeriodicalIF":11.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49194082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Use of pollution indices and ecological risk in the assessment of contamination from chemical elements in soils and sediments – Practical aspects 污染指数和生态风险在土壤和沉积物中化学元素污染评价中的应用。实用方面
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-09-01 DOI: 10.1016/j.teac.2022.e00169
Sergio L.C. Ferreira , Jucelino B. da Silva Junior , Ivanice Ferreira dos Santos , Olivia M.C. de Oliveira , Victor Cerda , Antonio F.S. Queiroz
{"title":"Use of pollution indices and ecological risk in the assessment of contamination from chemical elements in soils and sediments – Practical aspects","authors":"Sergio L.C. Ferreira ,&nbsp;Jucelino B. da Silva Junior ,&nbsp;Ivanice Ferreira dos Santos ,&nbsp;Olivia M.C. de Oliveira ,&nbsp;Victor Cerda ,&nbsp;Antonio F.S. Queiroz","doi":"10.1016/j.teac.2022.e00169","DOIUrl":"10.1016/j.teac.2022.e00169","url":null,"abstract":"<div><p>This paper presents a discussion involving practical aspects of applying contamination indices and ecological risk factors derived from chemical elements in the environmental assessment of soils and sediments. The single and integrated indices: Geoaccumulation index (<em>I</em><sub><em>geo</em></sub>), Enrichment factor (EF), Contamination factor (CF), Pollution Index (PI), Ecological risk factor (<em>E</em><sub>i</sub><sub><em>r</em></sub>), Pollution Load Index (PLI), Degree of contamination (C<sub>deg)</sub>, Modified Contamination Factor (<em>m</em>C<sub>deg</sub>), and potential ecological risk index (PERI) were discussed, and some applications were presented didactically. The analytical care needed to obtain reliable indices with the studied ecosystem is also evidenced. In addition, the advantages and limitations of the use of these indices are presented.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"35 ","pages":"Article e00169"},"PeriodicalIF":11.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46301953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Smart sensors in environmental/water quality monitoring using IoT and cloud services 使用物联网和云服务进行环境/水质监测的智能传感器
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-09-01 DOI: 10.1016/j.teac.2022.e00173
Víctor Garrido-Momparler , Miguel Peris
{"title":"Smart sensors in environmental/water quality monitoring using IoT and cloud services","authors":"Víctor Garrido-Momparler ,&nbsp;Miguel Peris","doi":"10.1016/j.teac.2022.e00173","DOIUrl":"10.1016/j.teac.2022.e00173","url":null,"abstract":"<div><p>The growing social awareness and consequent concern for the environment has driven environmental analytical chemistry to a position of great prominence. In recent times, this position has translated into taking advantage of the great benefits provided by cloud computing and the Internet of Things (IoT), which are especially appropriate when devices such as chemical sensors are used. The use of such sensors is very common when in situ monitoring of environmental parameters is performed, but until recently, it was limited to the deployment of a small number of sensors. Currently, this approach has given way to genuine smart sensing systems (for instance, fully consolidated wireless sensor networks) that are able to provide a substantial amount of information. This type of sensor (the so-called smart sensor) is fundamentally characterized by (a) low consumption, versatility, and autonomy, (b) ease of integration with cloud solutions, (c) durability and reliability of IoT platforms and sensors, and (d) easy installation and deployment of sensor nodes. For all these reasons, and given the increasing importance and use of this type of device, a revision of the recent literature relating the development of smart sensors with environmental issues has been conducted, with major contributions being discussed, most notably those addressing the continuous in-line monitoring of water quality.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"35 ","pages":"Article e00173"},"PeriodicalIF":11.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44545615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Microplastics and associated emerging contaminants in the environment: Analysis, sorption mechanisms and effects of co-exposure 微塑料和环境中相关的新出现的污染物:分析,吸附机制和共同暴露的影响
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-09-01 DOI: 10.1016/j.teac.2022.e00170
Julia Martín, Juan Luis Santos, Irene Aparicio, Esteban Alonso
{"title":"Microplastics and associated emerging contaminants in the environment: Analysis, sorption mechanisms and effects of co-exposure","authors":"Julia Martín,&nbsp;Juan Luis Santos,&nbsp;Irene Aparicio,&nbsp;Esteban Alonso","doi":"10.1016/j.teac.2022.e00170","DOIUrl":"10.1016/j.teac.2022.e00170","url":null,"abstract":"<div><p>Microplastics (MPs) and other emerging pollutants exist together in the environment and their co-exposure represents a source of increasing concern as MPs have been reported to act as carriers of pollutants due to their high sorption capacity. The ingestion of contaminated MPs by organisms can enhance the desorption of pollutants, increasing their bioavailability and toxicity. This review examines the role of MPs as vectors of environmental emerging contaminants. First, the main tools used to identify and characterise MPs and the analytical methods used for the determination of associated emerging contaminants are discussed. Insightful explanations of the sorption interaction between several groups of emerging pollutants and MPs are provided. MP type (polarity, crystallinity, size) and aging process together with the environmental conditions and pollutant properties (hydrophobicity and dissociated forms) are key factors influencing the sorption process. The literature review showed that polyethylene and polystyrene were the most commonly studied polymers. Antibiotics, perfluoroalkyl compounds and triclosan showed high sorption capacities onto MPs. Finally, the effect of co-exposure to MPs-emerging pollutants and bioaccumulation in aquatic and terrestrial organisms is discussed. The combined exposure may impact the toxic effects in different ways, through synergistic or antagonic interactions. Examples of different scenarios are provided, but in general the research conducted on terrestrial systems is scarce. The results revealed a lack of standardization in laboratory studies and in the testing conditions that reflect actual environmental exposure.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"35 ","pages":"Article e00170"},"PeriodicalIF":11.2,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214158822000174/pdfft?md5=348483ba52c9b872e771dd658d4cc7c7&pid=1-s2.0-S2214158822000174-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45628308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Artificial intelligence-based microfluidic platforms for the sensitive detection of environmental pollutants: Recent advances and prospects 基于人工智能的环境污染物敏感检测微流控平台:最新进展与展望
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-06-01 DOI: 10.1016/j.teac.2022.e00160
Niki Pouyanfar , Samaneh Zare Harofte , Maha Soltani , Saeed Siavashy , Elham Asadian , Fatemeh Ghorbani-Bidkorbeh , Rüstem Keçili , Chaudhery Mustansar Hussain
{"title":"Artificial intelligence-based microfluidic platforms for the sensitive detection of environmental pollutants: Recent advances and prospects","authors":"Niki Pouyanfar ,&nbsp;Samaneh Zare Harofte ,&nbsp;Maha Soltani ,&nbsp;Saeed Siavashy ,&nbsp;Elham Asadian ,&nbsp;Fatemeh Ghorbani-Bidkorbeh ,&nbsp;Rüstem Keçili ,&nbsp;Chaudhery Mustansar Hussain","doi":"10.1016/j.teac.2022.e00160","DOIUrl":"10.1016/j.teac.2022.e00160","url":null,"abstract":"<div><p>Environmental pollution and its drastic effects on human and animal health have urged governments to implement strict policies to minimize damage. The first step in applying such policies is to find reliable methods to detect pollution in various media, including water, food, soil, and air. In this regard, various approaches such as spectrophotometric, chromatographic, and electrochemical techniques have been proposed. To overcome the limitations associated with conventional analytical methods, microfluidic devices have emerged as sensitive technologies capable of generating high content information during the past few years. The passage of contaminant samples through the microfluidic channels provides essential details about the whole environment after detection by the detector. In the meantime, artificial intelligence is an ideal means to identify, classify, characterize, and even predict the data obtained from microfluidic systems. The development of microfluidic devices with integrated machine learning and artificial intelligence is promising for the development of next-generation monitoring systems. Combination of the two systems ensures time efficient setups with easy operation. This review article is dedicated to the recent developments in microfluidic chips coupled with artificial intelligence technology for the evolution of more convenient pollution monitoring systems.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"34 ","pages":"Article e00160"},"PeriodicalIF":11.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41833113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Recent advancement on chromo-fluorogenic sensing of aluminum(III) with Schiff bases 席夫碱对铝(III)的荧光传感研究进展
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-06-01 DOI: 10.1016/j.teac.2022.e00166
Patitapaban Mohanty , Rubi Behura , Vinita Bhardwaj , Pragyan Parimita Dash , Suban K. Sahoo , Bigyan R. Jali
{"title":"Recent advancement on chromo-fluorogenic sensing of aluminum(III) with Schiff bases","authors":"Patitapaban Mohanty ,&nbsp;Rubi Behura ,&nbsp;Vinita Bhardwaj ,&nbsp;Pragyan Parimita Dash ,&nbsp;Suban K. Sahoo ,&nbsp;Bigyan R. Jali","doi":"10.1016/j.teac.2022.e00166","DOIUrl":"10.1016/j.teac.2022.e00166","url":null,"abstract":"<div><p><span>The consumption of non-essential aluminum ion (Al</span><sup>3+</sup>) at higher concentration from biotic and abiotic sources can cause serious adverse effects to the human body. Therefore, there is bourgeoning need of developing facile analytical methods for the on-site and real-time monitoring of Al<sup>3+</sup> concentration in various environmental and biological samples. The chromo-fluorogenic based sensors have been widely developed in the recent years to detect and monitor Al<sup>3+</sup><span> ion. Among the various types of developed chemical sensors, the Schiff bases proved to have several advantages due to their facile synthesis with high yield, fascinating coordination behavior and easy structural modification. This review was narrated to compile the Schiff bases introduced recently for the sensing of Al</span><sup>3+</sup> in various environmental and biological samples. The designing of sensor, sensing mechanisms and other analytical novelties of the developed sensors are discussed.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"34 ","pages":"Article e00166"},"PeriodicalIF":11.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42094023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Metabolomics in environmental toxicology: Applications and challenges 代谢组学在环境毒理学中的应用和挑战
IF 11.2 2区 化学
Trends in Environmental Analytical Chemistry Pub Date : 2022-06-01 DOI: 10.1016/j.teac.2022.e00161
Carmen Bedia
{"title":"Metabolomics in environmental toxicology: Applications and challenges","authors":"Carmen Bedia","doi":"10.1016/j.teac.2022.e00161","DOIUrl":"10.1016/j.teac.2022.e00161","url":null,"abstract":"<div><p>Metabolomics is a discipline aiming to characterize the presence of metabolites in biological matrices under specific conditions. In recent years, metabolomics has increasingly been used in environmental research to explore the metabolic changes in humans and organisms under diverse environmental exposures, mainly chemical pollutants. Hence, metabolomics has become a key tool in exposome studies, to explore the biological effects at molecular level exerted by xenobiotics. To understand the biological mechanisms triggered by specific chemical compounds, the combination of metabolomics with information about the presence of xenobiotics in the biological samples (xenometabolome), and other molecular information obtained from omics technologies (e.g. transcriptomics, proteomics) is crucial, both in exposome studies, and adverse outcome pathways (AOPs) development.</p><p>This review aims to describe the main applications of metabolomics in the assessment of biological effects induced by chemical pollutants on ecosystems and human health, both in exposome studies and in laboratory-controlled assays. Different analytical aspects and recent analytical challenges are presented and discussed. Finally, the different opportunities and the current situation of metabolomics as a tool in chemical safety assessment for regulatory applications are reviewed.</p></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"34 ","pages":"Article e00161"},"PeriodicalIF":11.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214158822000083/pdfft?md5=6056691b7cd2897ee56c2766a935d51e&pid=1-s2.0-S2214158822000083-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46878299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
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