Journal of Stomatology Oral and Maxillofacial Surgery最新文献

{"title":"Evaluation of the influencing factors on facial development for mouth breathing children: Insights from 3D scanning technology","authors":"Bo Cheng ,&nbsp;Amin S. Mohamed ,&nbsp;Hongfei Li ,&nbsp;Yutong Li ,&nbsp;Jiawen Liu ,&nbsp;Lifeng Liu ,&nbsp;Rui Zou ,&nbsp;Fei Wang","doi":"10.1016/j.jormas.2025.102384","DOIUrl":"10.1016/j.jormas.2025.102384","url":null,"abstract":"<div><h3>Introduction</h3><div>Mouth breathing is considered a predisposing factor for sleep breathing disorders which may affect facial morphology, this study investigated the effect of age, gender, and breathing pattern on children's facial morphological development.</div></div><div><h3>Material and methods</h3><div><span>3dMD system (3dMD Inc., Atlanta, GA, USA) was utilized to acquire 3D images of the face. A total of 195 children aged 7–12 years were divided into 12 groups by age (7–8 years group, 9–10 years group,11–12 years group,), gender, and breathing pattern (mouth breathing MB, nasal breathing NB). A total of nineteen linear, angle, and ratio measurements were performed. Independent </span><em>t</em>-tests, Mann-Whitney <em>U</em><span> tests, One-way ANOVA tests and Kruskal-Wallis test were used to compare between the groups. Linear regression was used to test the relationship between age, gender, breathing patterns and facial development.</span></div></div><div><h3>Results</h3><div>In males, facial convexity angle (FCA) was significantly greater in the MB group than in the NB group in the 11–12 years age group (MB:17.82 ± 5.86, NB:13.24 ± 3.95, <em>P</em> = 0.023). In females, mandibular width increased with age only in the NB group (<em>P</em> &lt; 0.01); in the 9–10 years group, FCA was greater in the MB group than in the NB group (MB:19.03 ± 5.99, NB:14.3 ± 4.59, <em>P</em> = 0.036). In the 11–12 year old group, the mandibular width was significantly smaller in the MB group (MB:111.11 ± 6.34, NB:117.07 ± 8.53, <em>P</em> = 0.026) than in the NB group. Age (<em>P</em> &lt; 0.01) and gender (<em>P</em> &lt; 0.01) were correlated with mandibular width. Additionally, age (<em>P</em> &lt; 0.01), gender (<em>P</em> &lt; 0.01) and respiratory mode (<em>P</em> &lt; 0.05) were correlated with lower lip height.</div></div><div><h3>Discussion</h3><div>The upper mid-part development of the face increased with age, and MB showed a more convex profile in males and a narrower mandible in females. The lower third of the facial development was correlated with age, gender, and breathing pattern. Furthermore, mouth breathing was correlated with limitation of mandibular development and increased lower lip height.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102384"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anterior disc displacement without reduction: What happens after TMJ skeletal anchorage surgery? A retrospective cohort study","authors":"Linjian Huang ,&nbsp;Miaoran Li ,&nbsp;Xin Xu ,&nbsp;Zhijian Xie","doi":"10.1016/j.jormas.2025.102418","DOIUrl":"10.1016/j.jormas.2025.102418","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate surgery-related changes in condylar height, disc length, disc displacement, and tissue thickness of the temporomandibular joint<span> (TMJ) after skeletal anchorage surgery to obtain a better understanding of surgical outcomes and to provide useful information for treatment protocols.</span></div></div><div><h3>Methods</h3><div><span>This retrospective cohort study included 172 joints in 86 patients with unilateral anterior disc displacement without reduction (AddwoR), which were divided into an untreated group and an operation group. All patients had 2 magnetic resonance imaging records for measurement at the initial visit and follow-up visit respectively. The </span><em>t</em>-test was used to assess intra- and inter-group differences.</div></div><div><h3>Results</h3><div>In the untreated group, the changes in condylar height, disc length, and disc displacement on the AddwoR side were -0.98 mm, -0.11 mm and 0.74 mm, respectively. In the operation group, the changes in the condylar height, disc length, disc displacement and tissue thickness on the AddwoR side after anchorage surgery were 0.84 mm, 0.21 mm, -6.63 mm and -0.87 mm, respectively. A statistically significant difference was observed between the two groups.</div></div><div><h3>Conclusions</h3><div>The present study suggests that the condylar height and disc length of AddwoR without treatment tended to decrease with time. Additionally, TMJ skeletal anchorage surgery effectively reversed the decreases in condylar height and disc length. However, the findings suggest that TMJ anchorage surgery results in a decrease in tissue thickness. Preoperative tissue quality should be considered when planning surgical interventions to minimize the risk of tissue thinning.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102418"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between maxillofacial morphology and biomechanical environment in the TMJ during central clenching: A measurement and finite element analysis","authors":"Annan Li ,&nbsp;Bingmei Shao ,&nbsp;Zhan Liu","doi":"10.1016/j.jormas.2025.102420","DOIUrl":"10.1016/j.jormas.2025.102420","url":null,"abstract":"<div><h3>Background</h3><div>The relationship between maxillofacial morphology and temporomandibular disorders (TMD) is unclear. The stress distribution in temporomandibular joints (TMJs) was a key feature in understanding the pathogenesis of TMD.</div></div><div><h3>Methods</h3><div>Twenty-three subjects were scanned using MRI and CT in this study. The parameters of the subjects were measured. Finite element (FE) analyses were also conducted to evaluate the stress distribution in the TMJs. Paired correlations were then performed between the cephalometric parameters and FE results for the TMJs.</div></div><div><h3>Results</h3><div><span>The results showed the anterior cranial base and posterior </span>face<span> height tended to increase alongside a clockwise rotated mandible. A larger posterior ramal height and mandibular length, and clockwise rotated mandible with a forward position were favorable for maintaining the disc in an optimal position.</span></div></div><div><h3>Conclusions</h3><div>The morphology parameters are statistically related to the stress distributions in the TMJs. Even small changes in maxillofacial morphology could result in abnormal stress distributions in TMJs, potentially leading to TMD.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102420"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of osseous changes using radiomorphometric indices and fractal dimension in patients with systemic lupus erythematosus","authors":"Sevcihan Günen Yılmaz ,&nbsp;Ayşe Taş ,&nbsp;Seval Bayrak ,&nbsp;Selmi Yardimci ,&nbsp;Ali Rasat","doi":"10.1016/j.jormas.2025.102440","DOIUrl":"10.1016/j.jormas.2025.102440","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aims to evaluate the radiomorphometric indices and fractal dimension (FD) analysis on the digital panoramic radiography<span> (DPR) of patients with Systemic Lupus Erythematosus.</span></div></div><div><h3>Materials and methods</h3><div>This cross-sectional retrospective study included a total of 64 individuals. The panoramic mandibular index - inferior and panoramic mandibular index - superior (PMI-i, PMI-s), gonial index (GI), mandibular cortical index (MCI), and fractal dimension (FD) analysis values for all patients were computed on digital panoramic radiographs (DPRs). The statistical analysis of the entire dataset was conducted using SPSS version 22.</div></div><div><h3>Results</h3><div>The age and gender distributions in the Systemic Lupus Erythematosus group were comparable to those in the control group (<em>p</em> &gt; 0.05). The two groups did not exhibit statistically significant differences regarding PMI-i, PMI-s, GI, MCI, and FD analysis.</div></div><div><h3>Conclusion</h3><div>Our analysis revealed no significant differences in mandibular cortical and trabecular bone structure between healthy individuals and patients with Systemic Lupus Erythematosus. Given the absence of other studies on this topic, our findings necessitate further validation through the examination of clinical indicators.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102440"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral ridge augmentation using autogenous-xenogenic or allogenic-xenogenic graft mix with a cross-linked collagen membrane: a randomized pilot clinical trial","authors":"Celine El Rassi,&nbsp;Carole Chakar,&nbsp;Gabriel Menassa,&nbsp;Adam Saleh,&nbsp;Rawad Samarani","doi":"10.1016/j.jormas.2025.102442","DOIUrl":"10.1016/j.jormas.2025.102442","url":null,"abstract":"<div><div><span>The aim of the present trial is to compare in a horizontal guided bone regeneration clinical model, the allogenic-xenogenic combination to the autogenous-xenogenic combination. Edentulous ridges with less than 5 mm width were treated with guided bone regeneration using a </span>glutaraldehyde<span> cross-linked collagen membrane. Two graft combinations were used: autogenous-xenogenic (control group) or allogenic-xenogenic (test group). Ridge width measurements were recorded clinically and radiographically at 1, 3 and 5 mm from the ridge crest. Probe penetration was also recorded, and soft tissue healing was assessed during the follow-up visits. Core biopsies were retrieved for histological analysis. Four patients were recruited and randomly allocated to treatment groups with 12 sites of implant placement. 6 months after GBR surgery, all patients presented enough bone for implant placement. No difference was found between the groups in terms of clinical ridge width gain at the three levels of measurement. The mean percentage of graft resorption was 39.30 % and 29.31 % for control and test groups respectively, with no significant difference. In addition, no differences were found for probe penetration between the groups and no soft tissue complications occurred during follow-ups. Trends towards significance were evident for outcomes measurements. The protocol of this study should serve as a foundation for a larger-scale study with an improved population size.</span></div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102442"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic search and assessment of quality indicators in dental implantology","authors":"L. Verstraete ,&nbsp;T-M. Croonenborghs ,&nbsp;P-J. Verhelst ,&nbsp;E. Coeckelberghs ,&nbsp;K. Vanhaecht ,&nbsp;C. Politis ,&nbsp;J. Meeus","doi":"10.1016/j.jormas.2025.102494","DOIUrl":"10.1016/j.jormas.2025.102494","url":null,"abstract":"<div><div>Measuring quality in healthcare is essential to improve the best practices and optimizing the use of resources. Despite some Quality of Care (QoC) initiatives in other medical specialties, little is known about this topic in Dental Implantology (DI). The aim of this study was to identify and evaluate quality indicators (QIs) by performing an importance-performance analysis (IPA) for DI. Identification of QIs was done based on a systematic search. Importance was assessed by experts through an online survey and performance was evaluated with a monocenter, retrospective study. Finally, importance-perfomance plots were constructed to identify quality improvement targets with cut-offs for level of importance (&gt;75 %) and performance (&gt;80 %). A total of 12 QIs were selected varying between structure, process and outcome variables. 5 indicators met the cut-off levels indicating high levels of importance as well as performance. However, there is still a need for further research to validate these possible indicators and to evaluate their final effect on the QoC.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102494"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144621260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic evaluation of nasopalatine canal and its relationship with infraorbital foramen and foramen palatinum majus","authors":"Kübra Cam (Research Assistant) ,&nbsp;Tuna Sumer (Assistant) ,&nbsp;A. Zeynep Zengin (Professor)","doi":"10.1016/j.jormas.2025.102492","DOIUrl":"10.1016/j.jormas.2025.102492","url":null,"abstract":"<div><h3>Aim</h3><div>The aim of this study is to compare the morphological and dimensional characteristics of the nasopalatine canal (NPC) with those of the infraorbital foramen (IOF) and foramen palatinum majus (FPM) using cone beam computed tomography (CBCT).</div></div><div><h3>Material and Methods</h3><div><span>In CBCT images, the morphological characteristics and dimensional measurements of the three </span>anatomical structures (NPC, bilateral IOF, and FPM) were retrospectively analyzed. In the axial section, the widest diameter of the NPC was measured and categorized based on imaging; normal NPC: (≤6 mm), enlarged NPC (&gt;6 mm and ≤10 mm) and pathology-suspected group, (&gt;10 mm), radiographically suggestive of nasopalatine canal cysts (NPCC). This grouping was purely based on imaging findings and does not equate to a confirmed diagnosis of NPCC, as no histopathological verification was performed.</div></div><div><h3>Results</h3><div>70 patients were included in the normal NPC group, 70 patients in the enlarged NPC group, and 20 patients in the pathology-suspected NPC group. No statistically significant relationship was found between age, sex, and dentition status across the normal, enlarged, and pathology-suspected groups. The vertical diameter of the IOF was significantly higher in the enlarged and pathology-suspected groups. For the FPM, although an increasing tendency was observed bilaterally, statistically significant increases in A-P and M-L diameters were found only on the right side. (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>The results indicated that NPC enlargement is associated with increased dimensions of the IOF and FPM. Based on these findings, it can be suggested that individuals with a wider NPC, especially when accompanied by enlarged IOF and FPM, may have a higher radiographic risk profile for NPCC development.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102492"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"War as a teacher: Experiences of facial reconstruction with anterolateral thigh flap during the Ukrainian war","authors":"Bekir Osmanov ,&nbsp;Meslmäki Karri ,&nbsp;Tetiana Pavlychuk ,&nbsp;Tommy Wilkman ,&nbsp;Yurii Chepurnyi ,&nbsp;Johanna Snäll ,&nbsp;Andrii Kopchak","doi":"10.1016/j.jormas.2025.102407","DOIUrl":"10.1016/j.jormas.2025.102407","url":null,"abstract":"<div><h3>Background</h3><div><span>The Ukrainian conflict has led to a surge in combat-related facial injuries, characterized by complex soft tissue and bone defects<span> requiring microvascular reconstruction approaches. This study evaluates the efficacy of the </span></span>anterolateral thigh flap (ALTF) in addressing these challenges.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted on 21 patients with warrelated extensive facial bone<span> and soft tissue defects<span> treated at the Head and Neck Surgery Center, Kyiv Regional Hospital, between October 2022 and November 2023. Reconstruction primarily utilized ALTF, with supplementary osseous transplants or endoprostheses where indicated. Variables assessed included ALTF survival rate, complications, distinctive features, overall outcomes. The follow-up period was up to 26 months postoperatively.</span></span></div></div><div><h3>Results</h3><div><span><span>A full-thickness ALTF (skin, fat, fascia) with a median area of 40 cm² (IQR 36–60 cm²) was applied. In most cases (52.3 %), only one vessel perforator was identified. Isolated mucosal defects were observed in 19.0 % of patients, cutaneous defects in 33.3 %, and combined cutaneous and mucosal defects in 47.7 %. All surgeries were performed on a delayed basis, with a median interval of 157 days (IQR 107–132) between injury and reconstruction. The ALTF achieved a 90.5 % success rate, with two flaps failing intraoperatively and replaced by radial forearm </span>free flap<span> (RFFF). Donor site morbidity was minimal. Recipient site complications included postoperative hematoma and </span></span>wound dehiscence (4 cases each). Preoperative infection was common (47.7 %) but had limited impact on ALTF outcomes.</div></div><div><h3>Conclusion</h3><div>The ALTF demonstrates high versatility and reliability in reconstructing combat-related facial injuries, offering substantial tissue volume with minimal donor-site morbidity. It provides robust soft tissue coverage, creating favorable conditions for the restoration of underlying bone structures. Despite the high infection rates in military patients, the anatomical variability of the ALTF, and intraoperative challenges such as recipient vessel issues and defect configurations, the ALTF remains a preferred option for complex facial reconstructions in war trauma scenarios.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102407"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sclerosing odontogenic carcinoma: A systematic review of published case reports","authors":"Rezhat Abbas ,&nbsp;Nazifa Javaid","doi":"10.1016/j.jormas.2025.102438","DOIUrl":"10.1016/j.jormas.2025.102438","url":null,"abstract":"<div><h3>Background</h3><div>Sclerosing odontogenic carcinoma is a rare and locally invasive malignant tumor of odontogenic origin. Due to its low incidence, the literature is limited to isolated case reports, making comprehensive understanding of its clinicopathologic features and management strategies challenging.</div></div><div><h3>Objective</h3><div>This systematic review aims to synthesize the existing case reports on SOC to elucidate its clinical, radiographic, histopathological, and immunohistochemical characteristics, and to provide insights into current diagnostic and therapeutic approaches.</div></div><div><h3>Methods</h3><div>A comprehensive literature search was conducted across three major databases: PubMed, Scopus, and Embase. A total of 95 records were initially identified (PubMed: n = 36; Scopus: n = 30; Embase: n = 29). After screening and eligibility assessment, 16 studies meeting inclusion criteria were selected for final analysis.</div></div><div><h3>Results</h3><div><span><span>SOC predominantly involved the mandible<span>. The most commonly reported symptom was swelling, either painless or painful. Radiographically, lesions often appeared as ill-defined or poorly marginated radiolucencies, reflecting their infiltrative nature. Frequent cortical bone involvement included thinning, resorption, and perforation. Histopathologically, SOC was characterized by cords, nests, and strands of bland epithelial cells in a densely sclerotic </span></span>stroma. Immunohistochemically, tumors showed strong expression of high molecular weight </span>cytokeratins<span><span><span> (CK5/6, CK19, p63, AE1/AE3). The primary treatment modality was wide local excision with clear margins, commonly involving segmental </span>mandibulectomy or </span>maxillectomy based on tumor extent.</span></div></div><div><h3>Conclusion</h3><div>SOC is an exceptionally rare odontogenic malignancy with consistent clinical and pathological features across reported cases. Its locally aggressive nature underscores the importance of early diagnosis and wide surgical excision. This review consolidates existing case data to enhance understanding and aid clinicians in recognizing and managing this challenging neoplasm.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102438"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral and maxillofacial manifestations of Pycnodysostosis: a summary of clinical, radiological and cephalometric diagnostic criteria. A systematic review","authors":"M. Bovis ,&nbsp;A. Brotons ,&nbsp;D. Antunes ,&nbsp;T. Colard ,&nbsp;C. Philip-Alliez ,&nbsp;J. Ferri","doi":"10.1016/j.jormas.2025.102430","DOIUrl":"10.1016/j.jormas.2025.102430","url":null,"abstract":"<div><div><span><span><span><span>Pycnodysostosis (PYCD) is a rare osteosclerotic disorder with distinct craniofacial features. Diagnosis remains challenging due to overlap with other </span>skeletal dysplasias. The aim of this </span>systematic review was to identify clinical, radiological, and </span>cephalometric<span><span> maxillofacial features in PYCD and to evaluate their diagnostic relevance. Following PRISMA and AMSTAR guidelines, a search was conducted in Pubmed, Web of Science and Cochrane Library databases. Studies were included if they reported characteristics of the cranial vault, face, or oral cavity<span><span>. Of the 345 publications identified, 46 studies comprising a total of 69 patients were included. The cohort consisted of 58 % female and 42 % male patients, with a mean age of 20 years and a consanguinity<span> rate of 38 %. Key diagnostic features included frontal bossing (92 %), unclosed </span></span>cranial sutures<span><span> (97 %), sclerotic ossification (90 %), midfacial hypoplasia<span> (100 %), exorbitis (83 %), maxillary sinus<span><span> hypoplasia (97 %), micrognathia (92 %), severely obtuse gonial angle (100 %), narrow and grooved </span>palate (100–73 %) and severe </span></span></span>dental crowding (91 %). The </span></span></span>cephalometric analysis<span>, available for 17 patients, revealed maxillary and mandibular retrognathia (</span></span></span><em>p</em> = 9.17e-06 and 7.646e-05), with no predominance skeletal class, facial hyperdivergence (<em>p</em> = 0.047), and cranial base morphology contributing to these dysmorphies (<em>p</em> = 9,31e-04).</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102430"},"PeriodicalIF":2.0,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}