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AlphaFillはAlphaFoldモデルにリガンドやコファクターを補完する AlphaFill为AlphaFold模型补充配体和因子
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-07-25 DOI: 10.4052/tigg.2316.6j
N. Manabe
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引用次数: 0
ヒトノイラミニダーゼ1と関連する疾患 与人类神经氨酸酶1相关的疾病
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-07-25 DOI: 10.4052/tigg.2210.1j
Jun Tsukimoto, Kohji Itoh
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引用次数: 0
Site-specific Analysis of N-glycans of Receptor Tyrosine Kinases 受体酪氨酸激酶n -聚糖的位点特异性分析
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-07-25 DOI: 10.4052/tigg.2212.1e
Motoko Takahashi, N. Fujitani, Y. Uehara, Y. Hasegawa
{"title":"Site-specific Analysis of N-glycans of Receptor Tyrosine Kinases","authors":"Motoko Takahashi, N. Fujitani, Y. Uehara, Y. Hasegawa","doi":"10.4052/tigg.2212.1e","DOIUrl":"https://doi.org/10.4052/tigg.2212.1e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43830130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Neuraminidase 1 and Related Diseases 人类神经氨酸酶1及其相关疾病
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-07-25 DOI: 10.4052/tigg.2210.1e
Jun Tsukimoto, K. Itoh
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引用次数: 0
AlphaFill: Docking Ligands and Cofactors into AlphaFold Models AlphaFill:对接配体和辅因子到AlphaFold模型
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-07-25 DOI: 10.4052/tigg.2316.6e
N. Manabe
{"title":"AlphaFill: Docking Ligands and Cofactors into AlphaFold Models","authors":"N. Manabe","doi":"10.4052/tigg.2316.6e","DOIUrl":"https://doi.org/10.4052/tigg.2316.6e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47626561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a Synthetic Strategy for Gangliosides Using the Unique Chemical Structure of Sialic Acid 利用唾液酸独特的化学结构开发神经节苷合成策略
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-05-25 DOI: 10.4052/tigg.2312.2j
Hide-Nori Tanaka
{"title":"Development of a Synthetic Strategy for Gangliosides Using the Unique Chemical Structure of Sialic Acid","authors":"Hide-Nori Tanaka","doi":"10.4052/tigg.2312.2j","DOIUrl":"https://doi.org/10.4052/tigg.2312.2j","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42249781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design, Synthesis, and Characterization of Stapled Oligosaccharides 钉接寡糖的设计、合成和表征
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-05-25 DOI: 10.4052/tigg.2311.6e
Shinnosuke Wakamori
{"title":"Design, Synthesis, and Characterization of Stapled Oligosaccharides","authors":"Shinnosuke Wakamori","doi":"10.4052/tigg.2311.6e","DOIUrl":"https://doi.org/10.4052/tigg.2311.6e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46095120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Target-Specific <i>O</i>-linked <i>N</i>-acetylglucosamine Modification with a Dual-Specificity Aptamer Reveals Functions of <i>O</i>-GlcNAcylation in <i>β</i>-catenin 靶向特异性&lt;i&gt; o&gt;/i&gt;-连接&lt;i&gt;N&lt;/i&gt;-乙酰氨基修饰双特异性适配体揭示&lt;i&gt;O&lt;/i&gt;- glcn酰化在&lt;i&gt;β&lt;/i&gt;-catenin中的作用
4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-05-25 DOI: 10.4052/tigg.2309.6e
Haruki Odaka
{"title":"Target-Specific &lt;i&gt;O&lt;/i&gt;-linked &lt;i&gt;N&lt;/i&gt;-acetylglucosamine Modification with a Dual-Specificity Aptamer Reveals Functions of &lt;i&gt;O&lt;/i&gt;-GlcNAcylation in &lt;i&gt;β&lt;/i&gt;-catenin","authors":"Haruki Odaka","doi":"10.4052/tigg.2309.6e","DOIUrl":"https://doi.org/10.4052/tigg.2309.6e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134996417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular Aspects of Cancer-associated Glycans in Gliomas 胶质瘤中癌症相关聚糖的分子研究
4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-05-25 DOI: 10.4052/tigg.2306.2j
Yuki Ohkawa
{"title":"Molecular Aspects of Cancer-associated Glycans in Gliomas","authors":"Yuki Ohkawa","doi":"10.4052/tigg.2306.2j","DOIUrl":"https://doi.org/10.4052/tigg.2306.2j","url":null,"abstract":"哺乳類細胞は多種多様な糖鎖を発現しており、その発現パターンは糖転移酵素やその基質、糖分解酵素などによって厳密に制御されている。しかし、病変部においてはしばしば、糖鎖発現制御機構に異常が生じ、正常ではみられない糖鎖が発現する。特にがんにおいては、それら糖鎖の異所的な発現が同定され、その幾つかはバイオマーカーとして利用される一方で、治療標的として研究されている。本稿では著者とその研究グループがこれまでに明らかにしてきたガングリオシドGD3およびヘパラン硫酸グリコサミノグリカンの、グリオーマにおける悪性形質増強に寄与する分子機能を紹介する。","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134996418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glycoengineering for the Production of Lysosomal Enzymes 生产溶酶体酶的糖工程
IF 0.3 4区 生物学
Trends in Glycoscience and Glycotechnology Pub Date : 2023-05-25 DOI: 10.4052/tigg.2204.1e
Yu-He Tang, Ganglong Yang, Morihisa Fujita
{"title":"Glycoengineering for the Production of Lysosomal Enzymes","authors":"Yu-He Tang, Ganglong Yang, Morihisa Fujita","doi":"10.4052/tigg.2204.1e","DOIUrl":"https://doi.org/10.4052/tigg.2204.1e","url":null,"abstract":"","PeriodicalId":55609,"journal":{"name":"Trends in Glycoscience and Glycotechnology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47530956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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