Weixue Xiong, Xiaolu Sui, Zhaomin Xie, Tianrui Zhuang, Yanzi Zhang, Tingfei Xie, Aisha Zhang, Mahenderan Appukutty, Ran An, Jie Li, Jihong Chen
{"title":"Developmental conditions and adult socioeconomic context jointly shape cognitive aging through brain reserve.","authors":"Weixue Xiong, Xiaolu Sui, Zhaomin Xie, Tianrui Zhuang, Yanzi Zhang, Tingfei Xie, Aisha Zhang, Mahenderan Appukutty, Ran An, Jie Li, Jihong Chen","doi":"10.1080/13607863.2026.2719940","DOIUrl":"https://doi.org/10.1080/13607863.2026.2719940","url":null,"abstract":"<p><strong>Objectives: </strong>Cognitive aging shows substantial inter-individual heterogeneity, which may be shaped by both early-life developmental conditions and adult socioeconomic environments. However, how these life-course factors jointly relate to cognitive aging and the potential neuroanatomical correlates underlying these associations remain unclear.</p><p><strong>Methods: </strong>Using data from 35,105 UK Biobank participants with birth weight information, comprehensive cognitive assessments, and brain MRI, we examined associations between early-life growth and domain-specific cognitive performance in mid- to late adulthood, tested interactions with adult socioeconomic status (SES), and evaluated regional gray matter structures as potential mediators.</p><p><strong>Results: </strong>Low birth weight was associated with poorer performance in reasoning ability, memory, and executive function. Higher adult SES attenuated these associations, particularly for memory and executive functioning. Thalamic gray matter structure showed the strongest associations with cognitive performance and explained 17% to 44% of the association between birth weight and cognitive performance independent of adult SES.</p><p><strong>Conclusions: </strong>These findings suggest that higher adult socioeconomic resources may attenuate, but not fully offset, the adverse associations of early-life disadvantage, highlighting the importance of considering both early developmental conditions and adult social environments in understanding inequalities in cognitive aging.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-14"},"PeriodicalIF":2.9,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The variables influencing the quality of life of older adults with severe dementia in long-term care facilities.","authors":"Suet-Lai Leung, Timothy Chi-Yui Kwok","doi":"10.1080/13607863.2026.2712571","DOIUrl":"10.1080/13607863.2026.2712571","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine the clinical factors affecting the quality of life (QoL) of older adults with severe dementia in long-term care facilities.</p><p><strong>Methods: </strong>This was a cross-sectional study. Eligible participants were aged ≥ 65 years and at a severe stage of dementia. The dependent variable (QoL) was assessed using the Chinese version of the Quality of Life in Late-Stage Dementia Scale (QUALID-C). The independent variables included demographic data, behavioural symptoms, depression, cognitive function, self-care function, physical activity level and activity involvement.</p><p><strong>Results: </strong>A total of 81 participants (female= 70, mean age = 89.41 ± 6.68) were recruited. Behavioural problems and non-sedentary time were significantly associated with overall QoL in the multiple regression model (adjusted R<sup>2</sup>= 0.346, <i>p</i> = 0.001). Pain level, behavioural problems, non-sedentary time, involvement in daily activities, and length of stay were significantly associated with the discomfort QoL subscale in multiple regression (adjusted R<sup>2</sup>= 0.362, <i>p</i> = 0.000). For the comfort scale, behavioural problems were the only significant variable in the multiple regression model (adjusted R<sup>2</sup>= 0.256, <i>p</i> = 0.008).</p><p><strong>Conclusion: </strong>The results suggest that addressing behavioural problems and increasing non-sedentary time may enhance the overall QoL and alleviate discomfort in individuals with severe dementia in residential units.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-11"},"PeriodicalIF":2.9,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacob A Walker, Eleanor E Friedman, Jesus J Estrada, Samantha A Devlin, Jessica Schmitt, Annie Cwik, Mary Clare Masters, Shellie Williams, Moira C McNulty
{"title":"The HIV dementia Champion Program: using implementation science to adapt and embed dementia training within an HIV context.","authors":"Jacob A Walker, Eleanor E Friedman, Jesus J Estrada, Samantha A Devlin, Jessica Schmitt, Annie Cwik, Mary Clare Masters, Shellie Williams, Moira C McNulty","doi":"10.1080/13607863.2026.2717574","DOIUrl":"10.1080/13607863.2026.2717574","url":null,"abstract":"<p><strong>Background: </strong>Older adults with HIV (OAWH) face elevated dementia risk, yet dementia remains under-addressed in HIV care. Given the multidisciplinary nature of HIV clinics, there is unique opportunity to expand dementia care capacity by training HIV clinic staff.</p><p><strong>Methods: </strong>In this feasibility study we adapted Scotland's National Dementia Champions Programme for use in HIV clinics, creating the 'HIV Dementia Champion Program.' Implementation strategies focused on stakeholder engagement, local relevance, and sustainability. A community advisory board of OAWH guided program development. Training involved ten sessions with local dementia experts. Educational outcomes and implementation outcomes were measured <i>via</i> surveys. Assessments of program sustainability and cost were also conducted.</p><p><strong>Results: </strong>Four trainees completed the program. Educational performance was high at baseline with minimal change following training. Implementation outcomes indicated high acceptability, appropriateness, and feasibility. Sustainability scores were favorable, noting funding challenges. Community advisory board feedback was positive and highlighted interest in cognitive health.</p><p><strong>Conclusions: </strong>The HIV Dementia Champion Program is a feasible intervention for expanding dementia care capacity. Educational outcomes were modest but the program enhanced resource awareness and trainee confidence. This initiative demonstrates the potential of adapting geriatric training models to meet the needs of OAWH.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-9"},"PeriodicalIF":2.9,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond disruptive behaviors and caregiving burden: the role of family dynamics in potentially harmful behaviors by dementia informal caregivers.","authors":"Sheung-Tak Cheng, Linda C W Lam","doi":"10.1080/13607863.2026.2691371","DOIUrl":"https://doi.org/10.1080/13607863.2026.2691371","url":null,"abstract":"<p><strong>Objectives: </strong>Invoking the perspective that unpleasant behaviors can be transmitted within a family through social learning, emotional mimicry, and emotional displacement, the primary study objective is to examine whether negative family exchanges induce potentially harmful behaviors (PHB) by caregivers. The secondary objective is to clarify the causal relationship between burden and (care-recipient) challenging behaviors on the one hand, and PHB on the other, in light of the lack of longitudinal evidence.</p><p><strong>Methods: </strong>99 Alzheimer family caregivers participated in a 6-month 2-wave longitudinal survey. Ten items tapping psychological and physical domains were used to assess PHB. The quality of exchanges with each familial network member was measured using the social convoy questionnaire.</p><p><strong>Results: </strong>Controlling for baseline PHB in multiple regression, BPSD did not predict PHB at follow-up, but burden did. However, the effect of burden was reduced to nonsignificance after including family exchange variables. In the final model, only negative family exchanges significantly predicted PHB (<i>f</i><sup>2</sup> = 0.05), and this effect was not mediated by burden.</p><p><strong>Conclusion: </strong>Negative family exchanges contribute to caregivers' PHB over and above burden, underscoring the need to address the broader family dynamics in which caregiving is embedded in dementia care.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aimee Spector, H F Frederick Chan, Paige Williams, Konstadina Griva, Roopal Desai
{"title":"Cognition in menopause and the workplace: a call for global action.","authors":"Aimee Spector, H F Frederick Chan, Paige Williams, Konstadina Griva, Roopal Desai","doi":"10.1080/13607863.2026.2715762","DOIUrl":"https://doi.org/10.1080/13607863.2026.2715762","url":null,"abstract":"","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-6"},"PeriodicalIF":2.9,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148766196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The combined associations of physical activity and body mass index on the prevalence of functional difficulties among 29,343 individuals living with subjective cognitive decline: a cross-sectional study.","authors":"David Abernethy, Jason Bennie, Toby Pavey","doi":"10.1080/13607863.2026.2714184","DOIUrl":"10.1080/13607863.2026.2714184","url":null,"abstract":"<p><strong>Background: </strong>Functional difficulties associated with subjective cognitive decline (SCD) represent a public health concern. While physical activity (PA) and body mass index (BMI) are associated with cognitive health, their combined association with functional difficulties is unclear. This study examined the combined associations of PA and BMI on the prevalence of functional difficulties in a nationally representative sample of U.S. adults living with SCD.</p><p><strong>Methods: </strong>BRFSS data from 2011, 2015, 2017, and 2019 were pooled. Cross-sectional associations between independent and combined PA and BMI levels were estimated using Poisson log-linear regression and reported by Adjusted Prevalence Ratios (APRs).Results Data from 29,343 adults (≥18 years) were included. Compared to the reference group (Highly Active, Normal Weight), individuals with lower PA and increased BMI were more likely to report functional difficulties; APRs ranged from 1.10, 95% CI: 1.10-1.11 (Nonactive, Normal Weight) to 1.19, 95% CI: 1.18-1.19 (Nonactive, Obesity). Meeting PA guidelines reduced the prevalence of functional difficulties across all BMI categories, though benefits were smaller among individuals with obesity.</p><p><strong>Conclusion: </strong>Low PA and higher BMI were associated with greater prevalence of SCD functional difficulties. Guideline-level PA may reduce difficulties among BMI groups, but to a lesser extent among individuals living with obesity, supporting tailored PA strategies.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-13"},"PeriodicalIF":2.9,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan Ramphul, Yixiao Chen, Yanchen Liu, Jooyeon Lee, Carina Katigbak, Aanand D Naik, Jeffrey Kaye, Zachary Beattie
{"title":"Geospatial analysis of neighborhood characteristics and psychosocial outcomes among older adults: a cross-sectional community cohort study.","authors":"Ryan Ramphul, Yixiao Chen, Yanchen Liu, Jooyeon Lee, Carina Katigbak, Aanand D Naik, Jeffrey Kaye, Zachary Beattie","doi":"10.1080/13607863.2026.2714186","DOIUrl":"10.1080/13607863.2026.2714186","url":null,"abstract":"<p><strong>Objective: </strong>To assess whether neighborhood poverty, income, crime, and walkability are associated with psychosocial outcomes in older adults.</p><p><strong>Methods: </strong>We analyzed 198 of 301 participants from the Collaborative Aging Research Using Technology study in Oregon and Washington. Geocoded addresses were linked to census block-group and ½-mile buffer indicators. Single-exposure regression models, adjusted for age, gender, education, and neighborhood healthcare infrastructure, examined loneliness (UCLA Loneliness Scale), weekly lonely mood, anxiety (GAD-7), depressive symptoms (Geriatric Depression Scale), and weekly blue mood.</p><p><strong>Results: </strong>Lower median household income was associated with greater loneliness (p=.023). Higher crime risk was associated with increased weekly loneliness (p=.001), anxiety (OR=1.007; 95% CI: 1.001-1.013), and blue mood (p=.002). Greater walkability was also linked to blue mood (p=.035). No associations emerged for depressive symptoms. Indicators overlapped substantially (walkability-crime ρ≈0.78).</p><p><strong>Conclusions: </strong>Lower income was linked to chronic loneliness, while higher crime was consistently associated with weekly lonely mood, anxiety, and blue mood, suggesting safety-related exposures may be particularly salient for momentary emotional states. The absence of associations with depressive symptoms suggests trait-level depression may be less responsive to proximate environmental conditions than state-sensitive mood. These findings support community-level interventions targeting neighborhood safety among older adults aging in place.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-10"},"PeriodicalIF":2.9,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Financial strain and loneliness among older adults: the moderating role of neighborhood cohesion.","authors":"Lei Chai, Jong Hyun Jung","doi":"10.1080/13607863.2026.2715765","DOIUrl":"10.1080/13607863.2026.2715765","url":null,"abstract":"<p><strong>Objectives: </strong>This study examines the association between financial strain and loneliness among adults aged 66 years and older. Guided by stress-buffering and gender socialization perspectives, it also assesses whether neighborhood cohesion moderates this association and whether this moderation varies by gender.</p><p><strong>Methods: </strong>Using two waves of the United Kingdom Household Longitudinal Study that include measures of loneliness and neighborhood cohesion (<i>n</i> = 3,467 individuals; 6,934 person-wave observations), fixed-effects regression models examined whether within-individual changes in financial strain were associated with changes in loneliness over time. Interaction terms assessed moderation by neighborhood cohesion and whether this moderation varied by gender.</p><p><strong>Results: </strong>Financial strain was associated with increased loneliness over time, whereas higher neighborhood cohesion was associated with lower loneliness. Neighborhood cohesion attenuated the adverse association between financial strain and loneliness. Gender-stratified analyses showed that this buffering effect was statistically significant among women but not among men; however, the three-way interaction among financial strain, neighborhood cohesion, and gender was not statistically significant.</p><p><strong>Discussion: </strong>The findings highlight the need for community-based initiatives that foster neighborhood cohesion and for targeted financial support programs to reduce financial strain and its psychological consequences among older adults.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-11"},"PeriodicalIF":2.9,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Depressive and anxiety symptoms among community-dwelling older adults with diverse self-perceptions of aging: a network analysis perspective.","authors":"Guiying Yao, Yueyue Wang, Yanyan Luo, Junjun Sun, Xianghan Kong, Liyan Wang","doi":"10.1080/13607863.2026.2715085","DOIUrl":"https://doi.org/10.1080/13607863.2026.2715085","url":null,"abstract":"<p><strong>Objectives: </strong>This study explored the network structure of depressive and anxiety symptoms among community-dwelling older adults, compared networks between those with more negative or positive self-perceptions of aging (SPA), and examined direct associations between SPA and depressive-anxiety.</p><p><strong>Methods: </strong>A sample of 1,019 older adults from Xinxiang, China, was stratified by the Brief Aging Perceptions Questionnaire into more positive or negative group. Depression and anxiety symptoms were assessed via the PHQ-9 and GAD-7. Network centrality was measured using expected influence and bridge expected influence.</p><p><strong>Results: </strong>In the more negative SPA network, \"fatigue\", \"uncontrollable worry\", and \"feeling of worthlessness\" showed the highest expected influence. In the more positive SPA network, central symptoms were \"depressed or sad mood\", \"uncontrollable worry\", and \"worry too much\". Flow network analysis identified strong positive correlations between SPA and symptoms including \"afraid something will happen\", \"thoughts of death\", and \"feeling of worthlessness\".</p><p><strong>Conclusion: </strong>This was the first study to compare depression-anxiety networks across older adults with more positive versus negative SPA and investigate their associations. Targeting central symptoms may effectively alleviate depression and anxiety. Moreover, intervening on symptoms strongly linked to SPA may offer a novel route for improving SPA.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-11"},"PeriodicalIF":2.9,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claire S Wininger, Judy J Thomas, Megan W Wolk, Jennifer F Beatty-Wright, Patrick L Hill
{"title":"Personality, emotion regulation, and age-based discrimination: implications for wellbeing in older adulthood.","authors":"Claire S Wininger, Judy J Thomas, Megan W Wolk, Jennifer F Beatty-Wright, Patrick L Hill","doi":"10.1080/13607863.2026.2712570","DOIUrl":"https://doi.org/10.1080/13607863.2026.2712570","url":null,"abstract":"<p><strong>Methods: </strong>We sought to examine whether the negative associations between the two facets of ageism (internalized ageism and ageist discrimination) and psychological wellbeing are moderated by individual differences in personality, emotion regulation strategy use, and difficulties with strategy use in two cross-sectional studies.</p><p><strong>Results: </strong>Findings suggested that age-based discrimination and internalized ageism are associated with lower wellbeing. Extraversion, neuroticism, response modulation strategies, and difficulties with emotion regulation did not moderate ageism-wellbeing associations. However, use of engaged and disengaged cognitive change strategies did moderate the association between environmental mastery and internalized ageism, such that the effect of internalized ageism on environmental mastery was lessened.</p><p><strong>Conclusion: </strong>These findings are discussed with respect to the potential for applicable and implementable interventions for older adults.</p>","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-14"},"PeriodicalIF":2.9,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}