Aging & Mental Health最新文献_第10页

Climate change anxiety and sleep problems in the older adults. 老年人的气候变化焦虑和睡眠问题。

IF 2.8 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-01-17 DOI: 10.1080/13607863.2025.2452937

Havva Gezgin Yazıcı, Çiğdem Ökten, Latife Utaş Akhan

{"title":"Climate change anxiety and sleep problems in the older adults.","authors":"Havva Gezgin Yazıcı, Çiğdem Ökten, Latife Utaş Akhan","doi":"10.1080/13607863.2025.2452937","DOIUrl":"10.1080/13607863.2025.2452937","url":null,"abstract":"Objectives: Climate change has an impact on the prevalence of insufficient sleep and sleep disorders. This study aimed to examine climate change anxiety and sleep problems in older adults individuals.Method: This descriptive and cross-sectional study was carried out with 664 participants between July 9 and September 10, 2024. A Personal Information Form, the Climate Change Anxiety Scale, and the Insomnia Severity Index were used for data collection. In the data analysis, independent samples t-test and one-way analysis of variance were used to compare demographic variables with the climate change anxiety scale and insomnia severity index.Results: The mean age of the participants was 71.49 ± 6.21 years and more than half of the participants were female (54.4%). The mean score of the participants on the Climate Change Anxiety Scale was 1.68 ± 0.80 and their mean score on the Insomnia Severity Index was 12.56 ± 6.91. There was a positive correlation between the Climate Change Anxiety Scale and the Insomnia Severity Index (r = 0.26, p = 0.00). The insomnia variable explained 7% of the change in the Climate Change Anxiety score (R2 = 0.07, p = 0.00).Conclusion: Older adults experience anxiety and sleep problems regarding climate change and sleep problems in older adults increase as climate change anxiety increases.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1456-1460"},"PeriodicalIF":2.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preventable adverse events and related outcomes among people with dementia in hospital settings: scoping review. 住院痴呆患者的可预防不良事件和相关结局：范围回顾

IF 2.8 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-04-06 DOI: 10.1080/13607863.2025.2484355

Lucía Catalán, Déborah Oliveira

{"title":"Preventable adverse events and related outcomes among people with dementia in hospital settings: scoping review.","authors":"Lucía Catalán, Déborah Oliveira","doi":"10.1080/13607863.2025.2484355","DOIUrl":"10.1080/13607863.2025.2484355","url":null,"abstract":"Objectives: To explore the hospital-related adverse events endured by people with dementia and assess their association with negative outcomes related to hospital care.Method: A scoping review was undertaken in October 2023. Primary studies published in peer-reviewed journals in English, Spanish, or Portuguese were included. The databases PubMed, Web of Science, CINAHL, and Scopus were searched.Results: Of the 1976 retrieved studies, 16 were included. Adverse events were more frequent among people with dementia compared to people without dementia. In studies with non-surgical and surgical patients, the most frequently reported were falls, delirium, and infections, while in studies exclusively conducted with surgical patients, these were postoperative delirium, infections, and other complications. The link between adverse events and negative outcomes was explored in only three studies and indicated that those who experienced adverse events had longer hospital stays, higher risk of mortality, and higher readmission rates within 90 days.Conclusion: Although we were unable to establish a direct link between adverse events and hospital outcomes due to the exploratory nature of this review, the findings suggest that mitigating such events could help improve outcomes among hospitalized people with dementia. Hospital safety measures appear to be insufficient to protect this group.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1414-1425"},"PeriodicalIF":2.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding domains of awareness in Alzheimer's disease: a longitudinal study. 了解阿尔茨海默病的意识领域：一项纵向研究。

IF 2.8 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-04-06 DOI: 10.1080/13607863.2025.2486430

Isabel Barbeito Lacerda, Maria Alice Tourinho Baptista, Marcela Moreira Lima Nogueira, Tatiana Belfort, Felipe de Oliveira Silva, Marcia Cristina Nascimento Dourado

{"title":"Understanding domains of awareness in Alzheimer's disease: a longitudinal study.","authors":"Isabel Barbeito Lacerda, Maria Alice Tourinho Baptista, Marcela Moreira Lima Nogueira, Tatiana Belfort, Felipe de Oliveira Silva, Marcia Cristina Nascimento Dourado","doi":"10.1080/13607863.2025.2486430","DOIUrl":"10.1080/13607863.2025.2486430","url":null,"abstract":"Objectives: Awareness refers to the ability to recognize deficits associated with disease progression. This study aimed to investigate the pattern of impairment of domains of awareness over three-time points and examine the relationship between domains and clinical aspects of Alzheimer's Disease (AD).Method: We selected 158 people with mild-to-moderate AD and their caregivers. After 24 months, forty-one completed the evaluation. We examined five domains of awareness using the Assessment Scale of Psychological Impact of the Diagnosis of Dementia (ASPIDD): cognitive functioning and health condition, functional activity impairments, emotional state, social functioning and relationships, and disease itself.Results: We conducted a post-hoc analysis to understand impairment patterns across domains. Between moments 1 and 3, most domains showed significant impairments over time, except the ASPIDD emotional state, which remained stable. Principal Component Analysis indicated that ASPIDD emotional state and ASPIDD social functioning are similar; both were related to neuropsychiatric symptoms and caregiver burden during moments 1 and 2. Cognitive and functional factors impacted all domains during moment 3.Conclusion: The pattern of impairment in the domains of awareness is not a linear process since some domains did not decline over time. Each domain was influenced by different clinical aspects related to the disease.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1387-1397"},"PeriodicalIF":2.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reciprocal relationship between sense of control and social support: a random-intercept cross-lagged panel model. 控制感与社会支持的相互关系：一个随机截距交叉滞后面板模型。

IF 2.8 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-03-31 DOI: 10.1080/13607863.2025.2484354

Eunbea Kim, Gina Lee, Jeong Eun Lee, Peter Martin

{"title":"Reciprocal relationship between sense of control and social support: a random-intercept cross-lagged panel model.","authors":"Eunbea Kim, Gina Lee, Jeong Eun Lee, Peter Martin","doi":"10.1080/13607863.2025.2484354","DOIUrl":"10.1080/13607863.2025.2484354","url":null,"abstract":"Objectives: Although prior research has indicated the relationship between sense of control and social support in the context of older adults' well-being, little attention has been given to examining the inter-relationship between them longitudinally. Shedding light on the relationship between sense of control and social support, this study aimed to examine the reciprocal relationship between them, considering the two dimensions of sense of control (mastery/constraints) and the distinctive effects of different sources of social support (family/friends support). We also explored the gender differences in the associations.Method: This study included 9540 individuals 50 and older from the Health and Retirement study (HRS; 2006/2008, 2010/2012, 2014/2016, and 2018/2020). To observe intra-individual changes in the relationship between sense of control and social support over time, we used a random-intercept cross-lagged panel model with the four waves. We also conducted multi-group analyses to examine the moderating effect of gender on the associations.Results: We found that sense of control and social support were concurrently related. Although not consistent across waves, mastery and constraints predicted friends support among women.Conclusion: This study suggests that sense of control may emerge as significant for women's perceived social support from friends, while it may not hold the same importance for men.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1525-1534"},"PeriodicalIF":2.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12213213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Older adults' views and experiences of accessing secondary care mental health services in the community: a metasynthesis of qualitative literature. 老年人在社区获得二级保健精神卫生服务的观点和经验：定性文献的综合。

IF 2.4 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-04-21 DOI: 10.1080/13607863.2025.2489727

Jennifer Matthewson, Elizabeth Tyler, Steven Jones, Lucy Monk, Gillian Haddock

{"title":"Older adults' views and experiences of accessing secondary care mental health services in the community: a metasynthesis of qualitative literature.","authors":"Jennifer Matthewson, Elizabeth Tyler, Steven Jones, Lucy Monk, Gillian Haddock","doi":"10.1080/13607863.2025.2489727","DOIUrl":"10.1080/13607863.2025.2489727","url":null,"abstract":"Objectives: Research has highlighted under-utilisation of mental health services by older adults. This review aims to systematically review existing literature on older adults' experiences of accessing community mental health support from secondary care services. The review aims to develop recommendations to improve the mental health support older adults receive.Method: A comprehensive systematic search was conducted across four databases. Terms relating to older adult experiences and factors impacting access to secondary mental health community services were included. Nineteen eligible papers were identified. Data were thematically synthesised.Results: Four analytical themes and 12 descriptive subthemes were identified. Overarching themes included social influences and service factors which impacted engagement and accessibility, and personal factors. Sub-themes included mental health knowledge and beliefs, the impact of past experiences and social factors including discrimination and support. Help-seeking behaviours were influenced by accessibility of services, service support and clinician factors.Conclusion: Educational initiatives can help to increase mental health knowledge of older adults and their families allowing for improved access to services. Increased training for clinicians can improve referral processes and enable services to adapt to the unique needs of older adults. Studies reviewed were worldwide and reflected a range of views supporting relevance of outcomes globally.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1535-1545"},"PeriodicalIF":2.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

'Dementia has got two faces': grief as an experience of holding on and letting go for people living with primary progressive aphasia and posterior cortical atrophy. “痴呆症有两张面孔”：对于患有原发性进行性失语症和后皮层萎缩的人来说，悲伤是一种坚持和放手的经历。

IF 2.4 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-05-18 DOI: 10.1080/13607863.2025.2502793

Claire Waddington, Henry Clements, Sebastian Crutch, Martina Davis, Jonathan Glenister, Emma Harding, Erin Hope Thompson, Jill Walton, Joshua Stott

{"title":"'Dementia has got two faces': grief as an experience of holding on and letting go for people living with primary progressive aphasia and posterior cortical atrophy.","authors":"Claire Waddington, Henry Clements, Sebastian Crutch, Martina Davis, Jonathan Glenister, Emma Harding, Erin Hope Thompson, Jill Walton, Joshua Stott","doi":"10.1080/13607863.2025.2502793","DOIUrl":"10.1080/13607863.2025.2502793","url":null,"abstract":"Background: research on grief in people with primary progressive aphasia (PPA) and posterior cortical atrophy (PCA), is limited, despite the unique challenges these individuals face due to lack of understanding of their condition, younger age at onset and atypical symptom profile. The current study explores the losses people living with PPA or PCA experience and what helps to navigate these losses.Methods: in-depth semi-structured research conversations were conducted with 14 participants (n = 8 PCA, 6 PPA) to explore experiences of grief and loss related to their dementia. Data was analysed using abductive thematic coding techniques.Results: the impact and navigation of loss is reflected across five interconnecting themes: what I have lost, am losing and will lose, shared and unique sense of loss, balance between what is lost and what remains, changes in relationships and what helps in navigating loss.Conclusions: the dynamic interplay between what participants had lost and what they held on to carries significant implications for the design and delivery of support. These findings will be used alongside existing grief theory and interventional frameworks to develop a psychosocial intervention for people living with dementia.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1426-1438"},"PeriodicalIF":2.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12309460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of body dissatisfaction, lifestyle, and loneliness on emotional eating among older adults in Northeast China. 身体不满、生活方式和孤独感对东北老年人情绪性饮食的影响

IF 2.8 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-03-26 DOI: 10.1080/13607863.2025.2479188

Hua Ye, Ying Wang, Shiliang Xu, Jiajin Tu, Ming Hao, Xiaoliang Zhou

{"title":"The effects of body dissatisfaction, lifestyle, and loneliness on emotional eating among older adults in Northeast China.","authors":"Hua Ye, Ying Wang, Shiliang Xu, Jiajin Tu, Ming Hao, Xiaoliang Zhou","doi":"10.1080/13607863.2025.2479188","DOIUrl":"10.1080/13607863.2025.2479188","url":null,"abstract":"Objectives: Emotional eating is a psychological aspect of eating disorders. Recent studies have found that emotional eating is prevalent among older adults. This study aimed to investigate the current situation of emotional eating and explore the factors influencing emotional eating in older adults.Method: 1073 people aged 60 years and older were recruited from a community in Northeast China. Participants completed body measurements, emotional eating scale, sex-adapted silhouettes, Physical Activity Rating Scale, Loneliness Scale, and questionnaires.Results: Women had higher levels of emotional eating, loneliness, and body dissatisfaction thanmen. Multiple linear regression showed that loneliness (β = 0.29, p < 0.01), screen time (β = 0.29, p < 0.01), body dissatisfaction (β = 0.26, p < 0.01), BMI (β = 0.11, p < 0.01), and female sex (β = 0.07, p < 0.01) were risk factors for emotional eating, while physical activity (β = -0.18, p < 0.01) was a protective factor for emotional eating.Conclusion: Older adults with high levels of body dissatisfaction, may have higher levels of loneliness and lower levels of physical activity, are more likely to engage in emotional eating. These findings emphasize the influence of body dissatisfaction, loneliness, and physical activity on emotional eating in older adults in Northeast China.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1515-1524"},"PeriodicalIF":2.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insights from the eyes: a systematic review and meta-analysis of the intersection between eye-tracking and artificial intelligence in dementia. 来自眼睛的洞察：眼动追踪和人工智能在痴呆症中的交叉的系统回顾和荟萃分析。

IF 2.4 3区医学

Aging & Mental Health Pub Date : 2025-08-01 Epub Date: 2025-02-14 DOI: 10.1080/13607863.2025.2464704

Mahdi Norouzi, Rahele Kafieh, Paul Chazot, Daniel T Smith, Zahra Amini

{"title":"Insights from the eyes: a systematic review and meta-analysis of the intersection between eye-tracking and artificial intelligence in dementia.","authors":"Mahdi Norouzi, Rahele Kafieh, Paul Chazot, Daniel T Smith, Zahra Amini","doi":"10.1080/13607863.2025.2464704","DOIUrl":"10.1080/13607863.2025.2464704","url":null,"abstract":"Objectives: Dementia can change oculomotor behavior, which is detectable through eye-tracking. This study aims to systematically review and conduct a meta-analysis of current literature on the intersection between eye-tracking and artificial intelligence (AI) in detecting dementia.Method: PubMed, Embase, Scopus, Web of Science, Cochrane, and IEEE databases were searched up to July 2023. All types of studies that utilized eye-tracking and AI to detect dementia and reported the performance metrics, were included. Data on the dementia type, performance, artificial intelligence, and eye-tracking paradigms were extracted. The registered protocol is available online on PROSPERO (ID: CRD42023451996).Results: Nine studies were finally included with a sample size ranging from 57 to 583 participants. Alzheimer's disease (AD) was the most common dementia type. Six studies used a machine learning model while three used a deep learning model. Meta-analysis revealed the accuracy, sensitivity, and specificity of using eye-tracking and artificial intelligence in detecting dementia, 88% [95% CI (83%-92%)], 85% [95% CI (75%-93%)], and 86% [95% CI (79%-93%)], respectively.Conclusion: Eye-tracking coupled with AI revealed promising results in terms of dementia detection. Further studies must incorporate larger sample sizes, standardized guidelines, and include other dementia types.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1367-1375"},"PeriodicalIF":2.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Masculinity and memory loss: a qualitative study of the social stigma of dementia among Nigerian men. 男子气概和记忆丧失：尼日利亚男子痴呆症的社会耻辱的定性研究。

IF 2.4 3区医学

Aging & Mental Health Pub Date : 2025-07-31 DOI: 10.1080/13607863.2025.2541184

Sunkanmi Folorunsho, Beulah Suleman, Darlingtina Esiaka, Tejideen Olayinka, Victor Ajayi

{"title":"Masculinity and memory loss: a qualitative study of the social stigma of dementia among Nigerian men.","authors":"Sunkanmi Folorunsho, Beulah Suleman, Darlingtina Esiaka, Tejideen Olayinka, Victor Ajayi","doi":"10.1080/13607863.2025.2541184","DOIUrl":"https://doi.org/10.1080/13607863.2025.2541184","url":null,"abstract":"Objectives: Research on dementia in Nigeria has largely overlooked how gender norms shape older men's experiences. This study explored how cultural expectations of masculinity, emphasizing strength, independence, and authority, influence stigma, identity, and help-seeking among older Nigerian men with dementia.Method: A qualitative study was conducted using in-depth, semi-structured interviews with 19 men aged 60 and above receiving care for dementia related symptoms at two outpatient clinics in Ilorin, Kwara State. Data were analyzed thematically using grounded theory techniques.Results: Three themes emerged: Masculinity under threat, Stigma, silence, and social withdrawal, and Negotiating help seeking in a gendered context. Memory loss was perceived not only as cognitive decline but also as a threat to men's roles as household heads and decision makers. Participants described feelings of emasculation when reliant on others. Stigma led to concealment of symptoms and delayed help-seeking, with frequent reliance on spiritual remedies. Formal care was often pursued under family pressure, though some men reframed seeking care as fulfilling masculine duties.Conclusion: Findings show that masculinity shapes dementia experiences in Nigeria, influencing stigma, identity, and access to care. Gender-sensitive, culturally grounded interventions are needed to promote earlier diagnosis and support.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-10"},"PeriodicalIF":2.4,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144755203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insomnia, major depressive disorders, and risk for Alzheimer's disease and related dementias. 失眠，重度抑郁症，阿尔茨海默病和相关痴呆的风险。

IF 2.4 3区医学

Aging & Mental Health Pub Date : 2025-07-29 DOI: 10.1080/13607863.2025.2533495

SangNam Ahn, Joanne Salas, Jinmyoung Cho, Jeffrey F Scherrer

{"title":"Insomnia, major depressive disorders, and risk for Alzheimer's disease and related dementias.","authors":"SangNam Ahn, Joanne Salas, Jinmyoung Cho, Jeffrey F Scherrer","doi":"10.1080/13607863.2025.2533495","DOIUrl":"https://doi.org/10.1080/13607863.2025.2533495","url":null,"abstract":"Objectives: Insomnia and major depressive disorder (MDD) independently contribute to Alzheimer's disease and related dementias (ADRD). This study examined their combined associations with ADRD risk to inform targeted prevention and intervention strategies.Method: This retrospective cohort study used TriNetX electronic health records included dementia-free patients aged ≥50 years (n = 1,868,790; 2011-2023). Cox proportional hazards models, with entropy balancing adjustment, estimated hazard ratios (HRs) for ADRD risk overall and by race.Results: The cohort was 58% aged 50-64, 59% female, and 82% White. At baseline, 1.1% had both insomnia and MDD, 3.8% had insomnia only, 4.8% had MDD only, and 90.4% neither. ADRD incidence was 2.3% (28.8 per 10,000 person-years). Adjusted HRs showed a 91% higher risk for both conditions (HR = 1.91; 95% CI: 1.51-2.42), 11% for insomnia alone, and 70% for MDD alone. Race did not significantly modify these associations.Conclusion: Co-occurring insomnia and MDD markedly increase ADRD risk, with MDD as the primary contributor. Addressing sleep disturbances and depression may help lower dementia risk vulnerable populations.","PeriodicalId":55546,"journal":{"name":"Aging & Mental Health","volume":" ","pages":"1-10"},"PeriodicalIF":2.4,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0