American Journal of Forensic Medicine and Pathology最新文献_第2页

Metastatic Cardiac Tumor Mimicking Coronary Artery Aneurysm on Postmortem Computed Tomography. 在死后计算机断层扫描上模拟冠状动脉瘤的转移性心脏肿瘤。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-10 DOI: 10.1097/PAF.0000000000001038

Norihiro Shinkawa, Rina Yamada, Minako Azuma, Ninako Shinkawa, Nobuhiro Yukawa

引用次数: 0

Postmortem Computed Tomography Features of Necrotizing Epiglottis. 坏死性会厌的死后计算机断层扫描特征。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-04 DOI: 10.1097/PAF.0000000000001031

Vinod Khanijow, Kate O'Connor, Rexson Tse, Sinead McCarthy

引用次数: 0

Is Obesity a Factor in Lethal Opioid Toxicity? 肥胖是致死性阿片类药物毒性的一个因素吗？

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-04 DOI: 10.1097/PAF.0000000000001029

Jeremy W S Hunter, Corinna Van Den Heuvel, Lilli Stephenson, Ian F Musgrave, Roger W Byard

{"title":"Is Obesity a Factor in Lethal Opioid Toxicity?","authors":"Jeremy W S Hunter, Corinna Van Den Heuvel, Lilli Stephenson, Ian F Musgrave, Roger W Byard","doi":"10.1097/PAF.0000000000001029","DOIUrl":"https://doi.org/10.1097/PAF.0000000000001029","url":null,"abstract":"Abstract: Both obesity and opioid abuse are increasing in numbers globally. As these entities may be associated with significant respiratory compromise, it was hypothesized that synergism may occur and that as a result of this obese individuals may be more sensitive to the effects of opiates, that is, that deaths may occur at lower blood levels. To investigate this possibility, case files at Forensic Science SA, Adelaide Australia, were reviewed for all cases that occurred between 2000 and 2019 where deaths had been attributed to heroin or morphine toxicity. There were 259 cases (66 females, 193 males; age range: 18-91; average: 41.5). The average body mass index (BMI) was 26.8 (females, 26.1; males, 27.0). The total number of obese (BMI ≥ 30 < 40) decedents was 50, and the total number of morbidly obese (BMI ≥ 40) decedents was 17. No significant association was found in the obese or morbidly obese between BMI and postmortem drug levels of <0.01, ≥0.1 < 0.3, ≥0.3, <0.4, or ≥0.4 mg/L (P = 0.30, Fisher exact test). The lack of association between fatal postmortem opiate levels and BMI suggests that the negative respiratory effects of opioids and a high BMI may in some way be compensated for by as yet unidentified metabolic/pharmacokinetic factors in obesity.","PeriodicalId":55535,"journal":{"name":"American Journal of Forensic Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The National Association of Medical Examiners Eckert Memorial Award. 全国法医协会埃克特纪念奖。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2025-01-22 DOI: 10.1097/PAF.0000000000001001

引用次数: 0

Sudden Death Due to Necrotizing Fasciitis After Routine Cervical Radiofrequency Ablation Treatment. 常规宫颈射频消融治疗后因坏死性筋膜炎猝死。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-07-18 DOI: 10.1097/PAF.0000000000000976

Ravi Trivedi, Joyce L deJong, Patrick A Hansma

引用次数: 0

Suicide by Ethyl Methacrylate Ingestion. 摄入甲基丙烯酸乙酯自杀。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-08-02 DOI: 10.1097/PAF.0000000000000979

Samuel P Prahlow, Taylor Wilson, Amy C Gruszecki

{"title":"Suicide by Ethyl Methacrylate Ingestion.","authors":"Samuel P Prahlow, Taylor Wilson, Amy C Gruszecki","doi":"10.1097/PAF.0000000000000979","DOIUrl":"10.1097/PAF.0000000000000979","url":null,"abstract":"Abstract: This case report characterizes a unique way in which suicide was accomplished through ingestion of chemicals typically used to create acrylic fingernails that resulted in death. Ethyl methacrylate and acrylic powder are commonly combined to form acrylic nails in nail salons. The process of applying acrylic nails utilizes each substance by mixing both before it typically solidifies within seconds of combining the two compounds. Ingestion of these compounds has not been previously described within the medical literature. The decedent was a nail technician at a local salon. He was found unresponsive in his yard which led to a 911 call. At the scene, a mostly empty 16-oz bottle of ethyl methacrylate, a chemical used at the salon where he worked, was found. At autopsy, the decedent's body had a strong chemical odor consistent with odors present at nail salons. Significant gastrointestinal tract damage was seen including discoloration within the esophagus, and the stomach contained a molded, hardened nail compound. The cause of death was ruled as complications of nail acrylic powder and liquid ethyl methacrylate ingestion. This case shows the unusual findings seen at autopsy from a decedent who committed suicide by ingestion of ethyl methacrylate with acrylic powder.","PeriodicalId":55535,"journal":{"name":"American Journal of Forensic Medicine and Pathology","volume":" ","pages":"82-86"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caseous Calcification of the Mitral Annulus: Calcified Toothpaste of the Heart. 二尖瓣环钙化：心脏钙化牙膏。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-07-18 DOI: 10.1097/PAF.0000000000000971

Kyla M Jorgenson, Phillip D McMullen, Bruce I Goldman, Marisa Jacob-Leonce

{"title":"Caseous Calcification of the Mitral Annulus: Calcified Toothpaste of the Heart.","authors":"Kyla M Jorgenson, Phillip D McMullen, Bruce I Goldman, Marisa Jacob-Leonce","doi":"10.1097/PAF.0000000000000971","DOIUrl":"10.1097/PAF.0000000000000971","url":null,"abstract":"Abstract: Caseous calcification of the mitral annulus (CCMA) is a rare variant of mitral annular calcification (MAC) usually described as an antemortem finding. We report a case of sudden cardiac arrest in a 39-year-old male with end-stage renal disease undergoing hemodialysis with a history of Fabry disease by kidney biopsy. Autopsy revealed significant circumferential annular calcification in both mitral and aortic valves with a caseous gross appearance. Histologically, these areas consisted of amorphous basophilic material accompanied by a surrounding granulomatous-appearing infiltrate. Von Kossa staining on non-decalcified tissue revealed strong positive staining, confirming CCMA diagnosis. While identifiable, the atrioventricular node was displaced and distorted by caseous deposits. Toluidine blue staining of myocardium showed osmophilic accumulations, and electron microscopy (EM) showed myeloid/zebra bodies, consistent with Fabry disease. We posit that Fabry disease leads to end-stage kidney disease, altering calcium phosphate metabolism, a proposed mechanism for CCMA. This case highlights the multifactorial nature of sudden cardiac death in decedents with various structural cardiac changes and potential renal-disease-induced electrolyte imbalances. We aim to bring awareness to this rare entity, its potential role in a sudden cardiac death, and to highlight the need to use non-decalcified tissue when staining for calcium to establish the diagnosis.","PeriodicalId":55535,"journal":{"name":"American Journal of Forensic Medicine and Pathology","volume":" ","pages":"59-63"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11801426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141635961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiorgan Crystal Deposition in Acute Ethylene Glycol Toxicity. 急性乙二醇中毒中的多器官晶体沉积。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-10-14 DOI: 10.1097/PAF.0000000000000991

Matthew Uy, Kimberley Molina

引用次数: 0

Suicide by an Electric Power Drill and Spade Drill Bit: An Unusual Mechanism of Death. 使用电钻和铲形钻头自杀：一种不寻常的死亡机制。

IF 1 4区医学

American Journal of Forensic Medicine and Pathology Pub Date : 2025-03-01 Epub Date: 2024-07-16 DOI: 10.1097/PAF.0000000000000970

Trevor Watkins, Nathan Milne, Beng Beng Ong

引用次数: 0

The Mechanism of Death in Electrocution: A Historical Review of the Literature. 电刑的死亡机制：文献历史回顾。