Connie Y Chang, Joon-Yong Jung, Lia A Moulopoulos, Markus Wennmann
{"title":"The Global Reading Room: Imaging in Monoclonal Gammopathy of Undetermined Significance.","authors":"Connie Y Chang, Joon-Yong Jung, Lia A Moulopoulos, Markus Wennmann","doi":"10.2214/AJR.24.31464","DOIUrl":"10.2214/AJR.24.31464","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2431464"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141077287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment: Breast Cryoablation-A Promising Technology to Nonsurgically Treat Small Low-Risk Breast Cancer.","authors":"Eren D Yeh","doi":"10.2214/AJR.24.31346","DOIUrl":"10.2214/AJR.24.31346","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2431346"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Dustin Pooler, John W Garrett, Matthew H Lee, Benjamin E Rush, Adam J Kuchnia, Ronald M Summers, Perry J Pickhardt
{"title":"CT-Based Body Composition Measures and Systemic Disease: A Population-Level Analysis Using Artificial Intelligence Tools in Over 100,000 Patients.","authors":"B Dustin Pooler, John W Garrett, Matthew H Lee, Benjamin E Rush, Adam J Kuchnia, Ronald M Summers, Perry J Pickhardt","doi":"10.2214/AJR.24.32216","DOIUrl":"10.2214/AJR.24.32216","url":null,"abstract":"<p><p><b>BACKGROUND.</b> CT-based abdominal body composition measures have shown associations with important health outcomes. Advances in artificial intelligence (AI) now allow deployment of tools that measure body composition in large patient populations. <b>OBJECTIVE.</b> The purpose of this study was to assess associations of age, sex, and common systemic diseases with CT-based body composition measurements derived using a panel of fully automated AI tools in a population-level adult patient sample. <b>METHODS.</b> This retrospective study included 140,606 adult patients (67,613 men and 72,993 women; mean age, 53.1 ± 17.6 [SD] years) who underwent abdominal CT at a single academic institution between January 1, 2000, and February 28, 2021. CT examinations were not restricted on the basis of patient setting, clinical indication, or IV contrast media use. Thirteen fully automated AI body composition tools quantifying liver, spleen, and kidney volume and attenuation; vertebral trabecular attenuation; skeletal muscle area and attenuation; and abdominal fat area and attenuation were applied to each patient's first available abdominal CT examination. EHR review was performed to identify common systemic diseases, including cancer, cardiovascular disease (CVD), diabetes mellitus (DM), and cirrhosis, on the basis of relevant ICD-10 codes; 64,789 patients (46.1%) had at least one systemic disease diagnosed. Multiple linear regression models were performed for the 118,141 patients (84.0%) with no systemic disease or a single systemic disease, to assess age, sex, and the presence of systemic disease as predictors of body composition measures; effect sizes were characterized using the unstandardized regression coefficient <i>B</i>. <b>RESULTS.</b> Multiple linear regression models using age, sex, and systemic disease as predictors were overall significant for all 13 body composition measures (all <i>p</i> < .001) with variable goodness of fit (<i>R</i><sup>2</sup> = 0.03-0.43 across models). In the models, age was predictive of all 13 body composition measures; sex, 12 measures; cancer, nine measures; CVD, 11 measures; DM, 13 measures; and cirrhosis, 12 measures (all <i>p</i> < .05). <b>CONCLUSION.</b> Age, sex, and the presence of common systemic diseases were predictors of AI-derived CT-based body composition measures. <b>CLINICAL IMPACT.</b> An understanding of the identified associations with common systemic diseases will be critical for establishing normative reference ranges as CT-based AI body composition tools are developed for clinical use.</p>","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2432216"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mihan Lee, Pamela I Causa Andrieu, Stephanie Nougaret, Luca Russo, Sara Moufarrij, Jennifer J Mueller, Nadeem R Abu-Rustum, Christine O Menias, Yulia Lakhman
{"title":"Role of MRI in Assessing the Feasibility of Fertility-Sparing Treatments for Early-Stage Endometrial and Cervical Cancers.","authors":"Mihan Lee, Pamela I Causa Andrieu, Stephanie Nougaret, Luca Russo, Sara Moufarrij, Jennifer J Mueller, Nadeem R Abu-Rustum, Christine O Menias, Yulia Lakhman","doi":"10.2214/AJR.24.32157","DOIUrl":"10.2214/AJR.24.32157","url":null,"abstract":"<p><p>Fertility-sparing treatment (FST) has become a key aspect of managing gynecologic cancers in reproductive-age patients who wish to preserve fertility. Several leading clinical societies, including the European Society of Gynecological Oncology, the European Society for Radiotherapy and Oncology, the European Society of Pathology, and the European Society of Human Reproduction and Embryology, have published evidence-based guidelines on fertility-sparing strategies and post-treatment surveillance of patients with early-stage gynecologic cancers, in particular endometrial and cervical cancers. These guidelines highlight MRI as essential to initial patient selection and follow-up. Properly tailored pelvic MRI protocols and clear MRI reports are key to performing accurate staging, assessing eligibility, and confirming the initial and ongoing feasibility of FST. Accordingly, radiologists, particularly those specializing in gynecologic imaging, play a critical role in the multidisciplinary approach to FST. They should be well-versed in FST eligibility criteria and key MRI findings before and after FST, ensuring these details are comprehensively communicated in structured MRI reports.</p>","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2432157"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment: What Matters Most for Cystic Renal Masses?","authors":"Christian B van der Pol","doi":"10.2214/AJR.24.32619","DOIUrl":"10.2214/AJR.24.32619","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2432619"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to \"No Boundaries: Ethical and Practical Challenges of Implementing Artificial Intelligence in Radiology in Diverse Health Systems\".","authors":"Syed M A Bukhari, Sirui Jiang, Amit Gupta","doi":"10.2214/AJR.24.32529","DOIUrl":"10.2214/AJR.24.32529","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2432529"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment: Using Artificial Intelligence to Improve the Accuracy and Efficiency of Interpreting Thousands of Images in a CT Study.","authors":"James S Jelinek","doi":"10.2214/AJR.25.32665","DOIUrl":"10.2214/AJR.25.32665","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2532665"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment: Toward Meaningful Clinical Use of CT-Based Body Composition Metrics.","authors":"Jan Vosshenrich","doi":"10.2214/AJR.25.32664","DOIUrl":"10.2214/AJR.25.32664","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2532664"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Comment: Ensuring Patient-Centered Care With Screening Contrast-Enhanced Mammography-A Call to Action.","authors":"Vilert A Loving","doi":"10.2214/AJR.25.32684","DOIUrl":"10.2214/AJR.25.32684","url":null,"abstract":"","PeriodicalId":55529,"journal":{"name":"American Journal of Roentgenology","volume":" ","pages":"e2532684"},"PeriodicalIF":4.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}