Archiv Fur Tierzucht-Archives of Animal Breeding最新文献

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Antibiotic resistance and biofilm formation in Staphylococcus aureus isolated from dairy cows at the stage of subclinical mastitis in northern Kazakhstan. 哈萨克斯坦北部奶牛亚临床乳腺炎阶段分离金黄色葡萄球菌的抗生素耐药性和生物膜形成
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2022-01-01 DOI: 10.5194/aab-65-439-2022
Raushan Rychshanova, Anara Mendybayeva, Bartosz Miciński, Nurlan Mamiyev, Pavel Shevchenko, Zhanaidar Bermukhametov, Bartosz Orzechowski, Jan Miciński
{"title":"Antibiotic resistance and biofilm formation in <i>Staphylococcus aureus</i> isolated from dairy cows at the stage of subclinical mastitis in northern Kazakhstan.","authors":"Raushan Rychshanova,&nbsp;Anara Mendybayeva,&nbsp;Bartosz Miciński,&nbsp;Nurlan Mamiyev,&nbsp;Pavel Shevchenko,&nbsp;Zhanaidar Bermukhametov,&nbsp;Bartosz Orzechowski,&nbsp;Jan Miciński","doi":"10.5194/aab-65-439-2022","DOIUrl":"https://doi.org/10.5194/aab-65-439-2022","url":null,"abstract":"<p><p><i>Staphylococcus aureus</i> is an important causative agent of subclinical bovine mastitis worldwide. The aim of this research was to study the ability of <i>S. aureus</i> to form biofilms. Additionally, we examined the genes involved in cell resistance and sensitivity to antibiotics. Samples were collected from December 2020 to May 2021 from Simmental and black-and-white cows. The study was carried out on a total number of 643 cows, of which 278 (23 %) were in the subclinical mastitis stage. Finally, 64 <i>S. aureus</i> isolates were isolated and identified. The highest level of phenotypic resistance was observed to antibiotics of the tetracycline (tetracycline - 48.4 %, doxycycline - 32.8 %) and <math><mi>β</mi></math> -lactam (ampicillin - 45.3 %, penicillin - 45.3 %) groups. The genes encoding antibiotic resistance were characterized with the polymerase chain reaction method: <i>blaZ</i> in 30 isolates, <i>mecA</i> in 1 isolate, <i>ermC</i> in 15 isolates, <i>aph</i> (3) in 2 isolates, <i>tetK</i> in 19 isolates, <i>tetM</i> in 9 isolates. The tested <i>S. aureus</i> isolates had the ability to form biofilms in 76.6 % ( <math><mrow><mn>49</mn> <mo>/</mo> <mn>64</mn></mrow> </math> ) of cases. Of these, 69.4 % were resistant to at least one antibiotic. The obtained results have shown that <i>S. aureus</i>, identified in cows with subclinical mastitis, was resistant mainly to tetracycline and <math><mi>β</mi></math> -lactam antibiotics. In addition, <i>S. aureus</i> isolates expressed resistance genes to the above drugs and had the ability to form biofilm. This study will help to identify the extent of antibiotic resistance and monitor <i>S. aureus</i> contamination of raw milk.</p>","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"65 4","pages":"439-448"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901520/pdf/aab-65-439.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9252378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Screening of three-way crossbred combination and genetic effect analysis of the SNP in the CLPG gene in meat sheep. 肉羊CLPG基因三交组合筛选及SNP遗传效应分析。
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2022-01-01 DOI: 10.5194/aab-65-417-2022
Jian Tao Wang, Guo Sen Wang, Yuan Fang Gong, Xian Qiao, Xiang Li, Gui Zhu Wang, Ying Zhen Zheng, Jian Guo Lv, Xiang Long Li, Zheng Zhu Liu
{"title":"Screening of three-way crossbred combination and genetic effect analysis of the SNP in the <i>CLPG</i> gene in meat sheep.","authors":"Jian Tao Wang,&nbsp;Guo Sen Wang,&nbsp;Yuan Fang Gong,&nbsp;Xian Qiao,&nbsp;Xiang Li,&nbsp;Gui Zhu Wang,&nbsp;Ying Zhen Zheng,&nbsp;Jian Guo Lv,&nbsp;Xiang Long Li,&nbsp;Zheng Zhu Liu","doi":"10.5194/aab-65-417-2022","DOIUrl":"https://doi.org/10.5194/aab-65-417-2022","url":null,"abstract":"&lt;p&gt;&lt;p&gt;In order to promote the rapid development of the meat sheep industry, a three-way crossbred combination experiment was carried out with Australian White, Dorper, and Charollais sheep as terminal male parents and the elite F1 hybrids of Australian White  &lt;math&gt;&lt;mo&gt;×&lt;/mo&gt;&lt;/math&gt;  Small-tailed Han (Han), Dorper  &lt;math&gt;&lt;mo&gt;×&lt;/mo&gt;&lt;/math&gt;  Han, and Charollais  &lt;math&gt;&lt;mo&gt;×&lt;/mo&gt;&lt;/math&gt;  Han as female parents, which was based on the screening of a two-way crossbred combination in meat sheep. The growth performance of six groups of three-way crossbred combinations and Han lambs was measured and analyzed, and the effect of a polymorphism in the &lt;i&gt;CLPG&lt;/i&gt; gene on the growth performance of three-way crossbred lambs was also studied. The results showed that under the same rearing conditions, weight at 3 and 6 months of age and average daily gain from birth to 3 months and from 3 to 6 months of age were all the largest for Australian  &lt;math&gt;&lt;mo&gt;×&lt;/mo&gt;&lt;/math&gt;  (Charollais  &lt;math&gt;&lt;mo&gt;×&lt;/mo&gt;&lt;/math&gt;  Han) crossbred lambs. They were significantly or extremely significant different from the other three-way crossbred combinations and Han lambs ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mi&gt;&lt;&lt;/mi&gt; &lt;mn&gt;0.05&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; , &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mi&gt;&lt;&lt;/mi&gt; &lt;mn&gt;0.01&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ). The body height, body length, chest girth, and cannon bone circumference at 3 months of age and body length, chest girth, and cannon bone circumference at 6 months of age were also the largest for Australian  &lt;math&gt;&lt;mo&gt;×&lt;/mo&gt;&lt;/math&gt;  (Charollais  &lt;math&gt;&lt;mo&gt;×&lt;/mo&gt;&lt;/math&gt;  Han) crossbred lambs. Among them, body length, chest girth, and cannon bone circumference at 3 months of age were significantly different from the other three-way crossbred combinations and Han lambs ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mi&gt;&lt;&lt;/mi&gt; &lt;mn&gt;0.05&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), and body length, chest girth, and cannon bone circumference at 6 months of age were significantly or extremely significant different from the other three-way crossbred combinations and Han lambs ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mi&gt;&lt;&lt;/mi&gt; &lt;mn&gt;0.05&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; , &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mi&gt;&lt;&lt;/mi&gt; &lt;mn&gt;0.01&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ). The potential genetic effects of the &lt;i&gt;CLPG&lt;/i&gt; gene on the growth performance indicators of three-way crossbred lambs showed that a mutation site ( &lt;math&gt;&lt;mi&gt;g&lt;/mi&gt;&lt;/math&gt; .232 &lt;math&gt;&lt;mi&gt;C&lt;/mi&gt;&lt;/math&gt;   &lt;math&gt;&lt;mi&gt;&gt;&lt;/mi&gt;&lt;/math&gt;   &lt;math&gt;&lt;mi&gt;T&lt;/mi&gt;&lt;/math&gt; ) of this gene had two genotypes: &lt;i&gt;CC&lt;/i&gt; and &lt;i&gt;CT&lt;/i&gt;. Among them, the data of body weights and body sizes from &lt;i&gt;CT&lt;/i&gt; genotype individuals at birth, 3 months old, and 6 months old were significantly higher than those of &lt;i&gt;CC&lt;/i&gt; genotype individuals, and some indicators showed significant or extremely significant differences ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mi&gt;&lt;&lt;/mi&gt; &lt;mn&gt;0.05&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; , &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mi&gt;&lt;&lt;/mi&gt; &lt;mn&gt;0.01&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), suggesting that higher growth performance was observed in individuals with &lt;math&gt;&lt;mi&gt;T&lt;/mi&gt;&lt;/math&gt; alleles. To sum up, the cros","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"65 4","pages":"417-426"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9252377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic variation in the ovine KAP22-1 gene and its effect on wool traits in Egyptian sheep. 埃及羊KAP22-1基因的遗传变异及其对羊毛性状的影响。
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2022-01-01 DOI: 10.5194/aab-65-293-2022
Ahmed M Sallam, Aymen A Gad-Allah, Essam M Albetar
{"title":"Genetic variation in the ovine <i>KAP22-1</i> gene and its effect on wool traits in Egyptian sheep.","authors":"Ahmed M Sallam,&nbsp;Aymen A Gad-Allah,&nbsp;Essam M Albetar","doi":"10.5194/aab-65-293-2022","DOIUrl":"https://doi.org/10.5194/aab-65-293-2022","url":null,"abstract":"&lt;p&gt;&lt;p&gt;The objective of this study was to investigate the genetic polymorphisms in the keratin-associated protein (&lt;i&gt;KAP22-1&lt;/i&gt;) gene in Barki ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;n&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;206&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), Rahmani ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;n&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;28&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ) and Ossimi ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;n&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;28&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ) as the three major sheep breeds in Egypt. Subsequently, the detected variants were correlated with important wool traits. The traits included greasy fleece weight (GFW, g), staple length (SL, cm), prickle factor (PF, %), medullated fiber (MF, %), fiber diameter (FD, &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;µ&lt;/mi&gt;&lt;/mrow&gt; &lt;/math&gt; m), crimp percentage (CR, %) and the standard deviation of FD (SD &lt;math&gt;&lt;msub&gt;&lt;mi&gt;&lt;/mi&gt; &lt;mi&gt;fd&lt;/mi&gt;&lt;/msub&gt; &lt;/math&gt; , &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;µ&lt;/mi&gt;&lt;/mrow&gt; &lt;/math&gt; m), as well as the subjectively assessed traits of kemp score (KS), handle grade (HG), greasy color grade (GCG), bulk grade (BG), luster grade (LG) and staple structure (SST). Animals were genotyped by polymerase chain reaction (PCR) - single strand conformation polymorphism (SSCP). Five SSCP banding patterns representing three different nucleotide variants (A, B and C) were detected. DNA sequencing confirmed three single nucleotide polymorphisms (SNPs). Animal age significantly affected GFW ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.007&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), SD &lt;math&gt;&lt;msub&gt;&lt;mi&gt;&lt;/mi&gt; &lt;mi&gt;fd&lt;/mi&gt;&lt;/msub&gt; &lt;/math&gt; ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.006&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), SL ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.002&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), CR ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.006&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), KS ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.001&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), LG ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.006&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ) and SST ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.013&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ). Likewise, the breed had a significant effect on all studied traits except HG and BG, which was not significant. Results showed significant associations between the &lt;i&gt;KAP22-1&lt;/i&gt; variants and CR ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.01&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), SL ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.012&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ), KS ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;&lt;&lt;/mo&gt; &lt;mn&gt;0.001&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ) and GCG ( &lt;math&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.01&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ). Interestingly, animals with BB genotypes tended to produce more wool yield ( &lt;math&gt;&lt;mrow&gt;&lt;mn&gt;1163.63&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;65.91&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt;  g) with high SL ( &lt;math&gt;&lt;mrow&gt;&lt;mn&gt;8.38&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;0.20&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt;  cm), CR ( &lt;math&gt;&lt;mrow&gt;&lt;mn&gt;8.38&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;0.21&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt;  %) and KS ( &lt;math&gt;&lt;mrow&gt;&lt;mn&gt;1.98&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;1.88&lt;/mn&gt;&lt;/mrow&gt; &lt;/math&gt; ). Results of this study strongly recommend the &lt;i&gt;KAP22-1&lt;/i&gt; gene as a candidate gene for wool production traits in Egyptian sheep, with new useful insights into the visually assessed wool traits. The identified genetic markers may be incorporated into bree","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"65 3","pages":"293-300"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9399921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Meta-analysis of association between c.963A>G single-nucleotide polymorphism on BMP15 gene and litter size in goats. 山羊BMP15基因c.963A>G单核苷酸多态性与产仔数相关性的meta分析
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2022-01-01 DOI: 10.5194/aab-65-309-2022
Emel Zergani, Amir Rashidi, Jalal Rostamzadeh, Mohammad Razmkabir, Jens Tetens
{"title":"Meta-analysis of association between c.963A<i>></i>G single-nucleotide polymorphism on <i>BMP15</i> gene and litter size in goats.","authors":"Emel Zergani,&nbsp;Amir Rashidi,&nbsp;Jalal Rostamzadeh,&nbsp;Mohammad Razmkabir,&nbsp;Jens Tetens","doi":"10.5194/aab-65-309-2022","DOIUrl":"https://doi.org/10.5194/aab-65-309-2022","url":null,"abstract":"<p><p>Litter size is an important economic trait in the goat industry. Previous studies on the bone morphogenetic protein 15 (<i>BMP15</i>) gene detected some single-nucleotide polymorphisms (SNPs) such as c.963A <math><mi>></mi></math> G that were associated with an increase in ovulation rate and litter size. The aim of this study was to conduct a meta-analysis on the effect of this polymorphism on litter size. We gathered and pooled data from five eligible published studies. To investigate the effect of c.963A <math><mi>></mi></math> G on litter size, we utilized four different genetic models assuming dominant (<i>GG</i>  <math><mo>+</mo></math>  <i>GA</i> vs. <i>AA</i>), recessive (<i>GG</i> vs. <i>GA</i>  <math><mo>+</mo></math>  <i>AA</i>), additive (<i>GG</i> vs. <i>AA</i>) and co-dominant (<i>GG</i>  <math><mo>+</mo></math>  <i>AA</i> vs. <i>GA</i>) model of inheritance. Data were analyzed under random-effects models based on the <math> <mrow><msup><mi>I</mi> <mn>2</mn></msup> </mrow> </math> value. Furthermore, sensitivity analysis was carried out to validate the stability of results. The results showed that the c.963A <math><mi>></mi></math> G polymorphism is associated with litter size when applying a dominant model (standardized mean difference (SMD) is 0.815, 95 % CI [0.170, 1.461], <math><mi>P</mi></math>  value  <math><mo>=</mo></math>  0.013) and also with an additive model (SMD  <math><mo>=</mo></math>  0.755, 95 % CI [0.111, 1.400], <math><mi>P</mi></math>  value  <math><mo>=</mo></math>  0.022). However, the effect of c.963A <math><mi>></mi></math> G polymorphism was not significant under recessive (SMD  <math><mo>=</mo></math>  0.186, 95 % CI [ <math><mo>-</mo></math> 0.195, 4.259], <math><mi>P</mi></math>  value  <math><mo>=</mo></math>  0.339) and co-dominant (SMD  <math><mo>=</mo></math>   <math><mo>-</mo></math> 0.119, 95 % CI [ <math><mo>-</mo></math> 0.525, 0.288], <math><mi>P</mi></math>  value  <math><mo>=</mo></math>  0.568) models. Sensitivity analysis demonstrated that dropping studies with wide confidence intervals affects overall results under the assumption of an additive model. The meta-analysis results revealed that the <i>AA</i> genotype could be positively connected with litter size in goats.</p>","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"65 3","pages":"309-318"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9901516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9237787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Single-nucleotide polymorphisms in FLT3, NLRP5, and TGIF1 are associated with litter size in Small-tailed Han sheep. FLT3、NLRP5和TGIF1基因的单核苷酸多态性与小尾寒羊的产仔数有关。
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2021-12-17 eCollection Date: 2021-01-01 DOI: 10.5194/aab-64-475-2021
Si Chen, Lin Tao, Xiaoyun He, Ran Di, Xiangyu Wang, Mingxing Chu
{"title":"Single-nucleotide polymorphisms in <i>FLT3</i>, <i>NLRP5</i>, and <i>TGIF1</i> are associated with litter size in Small-tailed Han sheep.","authors":"Si Chen,&nbsp;Lin Tao,&nbsp;Xiaoyun He,&nbsp;Ran Di,&nbsp;Xiangyu Wang,&nbsp;Mingxing Chu","doi":"10.5194/aab-64-475-2021","DOIUrl":"https://doi.org/10.5194/aab-64-475-2021","url":null,"abstract":"<p><p>Previous studies have indicated that <i>FLT3</i>, <i>NLRP5</i>, and <i>TGIF1</i> play a pivotal role in sheep fecundity. Nevertheless, little is known about the association of the polymorphisms of these genes with litter size (LS). In this study, the selected single-nucleotide polymorphisms (SNPs) were genotyped using a Sequenom MassARRAY® platform, and the distribution of different genotypes of the SNPs in the seven sheep breeds (Small-tailed Han, Hu, Cele Black, Suffolk, Tan, Prairie Tibetan, and Sunite sheep) were analyzed. The reliability of the estimated allele frequency for all seven SNPs was at least 0.9545. Given the association of the <i>TGIF1</i> g.37866222C  <math><mo>></mo></math>  T polymorphism with LS in Small-tailed Han sheep ( <math><mrow><mi>p</mi> <mo><</mo> <mn>0.05</mn></mrow> </math> ), fecundity differences might be caused by the change in amino acid from proline (Pro) to serine (Ser), which has an impact on secondary, tertiary protein structures with concomitant <i>TGIF1</i> functionality changes. The <i>FLT3</i> rs421947730 locus has a great effect on the LS ( <math><mrow><mi>p</mi> <mo><</mo> <mn>0.05</mn></mrow> </math> ), indicating that the locus of <i>FLT3</i> in synergy with <i>KILTG</i> is likely to facilitate ovarian follicle maturation and ovulation. Moreover, <i>NLRP5</i> rs426897754 is associated with the LS of the second and third parities ( <math><mrow><mi>p</mi> <mo><</mo> <mn>0.05</mn></mrow> </math> ). We speculate that a synonymous variant of <i>NLRP5</i> may be involved in folliculogenesis accompanied by BMP15, FSHR, BMPR1B, AMH, and GDF9, resulting in the different fecundity of Small-tailed Han sheep. Our studies provide valuable genetic markers for sheep breeding.</p>","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"64 2","pages":"475-486"},"PeriodicalIF":0.0,"publicationDate":"2021-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8738861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39818634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Steroid hormonal endpoints in goats carrying single or twin fetuses reared in semi-extensive systems. 半放养系统中携带单胎或双胎山羊的类固醇激素终点。
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2021-12-09 eCollection Date: 2021-01-01 DOI: 10.5194/aab-64-467-2021
Luigi Liotta, Arianna Bionda, Deborah La Fauci, Marco Quartuccio, Rosanna Visalli, Esterina Fazio
{"title":"Steroid hormonal endpoints in goats carrying single or twin fetuses reared in semi-extensive systems.","authors":"Luigi Liotta,&nbsp;Arianna Bionda,&nbsp;Deborah La Fauci,&nbsp;Marco Quartuccio,&nbsp;Rosanna Visalli,&nbsp;Esterina Fazio","doi":"10.5194/aab-64-467-2021","DOIUrl":"https://doi.org/10.5194/aab-64-467-2021","url":null,"abstract":"<p><p>The study provides baseline data regarding 17- <math><mi>β</mi></math> -estradiol (E <math><msub><mi></mi> <mn>2</mn></msub> </math> ), progesterone (P <math><msub><mi></mi> <mn>4</mn></msub> </math> ), and cortisol profile of 30 Nicastrese goats during different physiological periods. Animals were evaluated monthly from the pre-mating period (non-pregnant), during pregnancy, and from 30 to 105 d of lactation. The effects of single or twin births and the kid's sex were also considered. Serum E <math><msub><mi></mi> <mn>2</mn></msub> </math> , P <math><msub><mi></mi> <mn>4</mn></msub> </math> , and cortisol concentrations were measured using immunoenzymatic assay kits. The highest concentrations of E <math><msub><mi></mi> <mn>2</mn></msub> </math> and P <math><msub><mi></mi> <mn>4</mn></msub> </math> ( <math><mrow><mi>P</mi> <mo><</mo> <mn>0.0001</mn></mrow> </math> ) were found during pregnancy and their lowest values ( <math><mrow><mi>P</mi> <mo><</mo> <mn>0.0001</mn></mrow> </math> ) in the non-pregnant period. E <math><msub><mi></mi> <mn>2</mn></msub> </math> was negatively correlated with P <math><msub><mi></mi> <mn>4</mn></msub> </math> ( <math><mrow><mi>r</mi> <mo>=</mo> <mo>-</mo> <mn>0.41</mn></mrow> </math> ; <math><mrow><mi>P</mi> <mo><</mo> <mn>0.01</mn></mrow> </math> ) during lactation. The mothers with twin kids showed the highest concentration of P <math><msub><mi></mi> <mn>4</mn></msub> </math> ( <math><mrow><mi>P</mi> <mo><</mo> <mn>0.04</mn></mrow> </math> ) at <math><mo>></mo></math>  95-115 d of gestation and the lowest of E <math><msub><mi></mi> <mn>2</mn></msub> </math> ( <math><mrow><mi>P</mi> <mo><</mo> <mn>0.04</mn></mrow> </math> ) at <math><mo>></mo></math>  50-70 d of lactation. Pregnant goats carrying male kid(s) presented the highest E <math><msub><mi></mi> <mn>2</mn></msub> </math> concentrations ( <math><mrow><mi>P</mi> <mo><</mo> <mn>0.02</mn></mrow> </math> ) at <math><mo>></mo></math>  130-150 d of gestation. Different physiological conditions induced a temporal relationship with the endocrine profile in Nicastrese goats. Understanding the effects of single or twin fetuses on the gestation and lactation will also be helpful to improve the managemental approach for the health of mothers and their kids.</p>","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"64 2","pages":"467-474"},"PeriodicalIF":0.0,"publicationDate":"2021-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8672451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39852989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Techniques for the Production of Transgenic Livestock 转基因牲畜生产技术
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2021-12-07 DOI: 10.1201/9781315137483-12
W. Eyestone, A. J. Clark
{"title":"Techniques for the Production of Transgenic Livestock","authors":"W. Eyestone, A. J. Clark","doi":"10.1201/9781315137483-12","DOIUrl":"https://doi.org/10.1201/9781315137483-12","url":null,"abstract":"","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75173921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Introduction: Current Animal Breeding 介绍:当前动物育种
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2021-12-07 DOI: 10.1201/9781315137483-1
C. Smith, A. J. Clark
{"title":"Introduction: Current Animal Breeding","authors":"C. Smith, A. J. Clark","doi":"10.1201/9781315137483-1","DOIUrl":"https://doi.org/10.1201/9781315137483-1","url":null,"abstract":"","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73188047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping Genes Underlying Production Traits in Livestock 家畜生产性状的基因定位
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2021-12-07 DOI: 10.1201/9781315137483-7
M. Georges
{"title":"Mapping Genes Underlying Production Traits in Livestock","authors":"M. Georges","doi":"10.1201/9781315137483-7","DOIUrl":"https://doi.org/10.1201/9781315137483-7","url":null,"abstract":"","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74460514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Modification of Production Traits 生产性状的改良
3区 农林科学
Archiv Fur Tierzucht-Archives of Animal Breeding Pub Date : 2021-12-07 DOI: 10.1201/9781315137483-13
V. Pursel, A. J. Clark
{"title":"Modification of Production Traits","authors":"V. Pursel, A. J. Clark","doi":"10.1201/9781315137483-13","DOIUrl":"https://doi.org/10.1201/9781315137483-13","url":null,"abstract":"","PeriodicalId":55481,"journal":{"name":"Archiv Fur Tierzucht-Archives of Animal Breeding","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76717749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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