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Archives of Disease in Childhood-Education and Practice Edition最新文献

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Fifteen-minute consultation: Maintenance and reliever therapy for the management of asthma in children and young people. 15分钟咨询：儿童和青少年哮喘管理的维持和缓解治疗。
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-09-18 DOI: 10.1136/archdischild-2024-327734
Angela Tang, Sebastian Jason Gray, Gary Connett, Katharine Pike
{"title":"Fifteen-minute consultation: Maintenance and reliever therapy for the management of asthma in children and young people.","authors":"Angela Tang, Sebastian Jason Gray, Gary Connett, Katharine Pike","doi":"10.1136/archdischild-2024-327734","DOIUrl":"10.1136/archdischild-2024-327734","url":null,"abstract":"<p><p>Asthma is the most common chronic disease of childhood. Acute asthma attacks are a frequent reason for emergency presentation in children and young people (CYP), and fatal asthma attacks can occur even in those thought to have mild disease. Asthma treatment in the UK has until recently relied heavily on a strategy of regular 'maintenance' inhaled corticosteroid (ICS) and separate 'reliever' inhalers containing short-acting beta-agonist (SABA) taken as needed to relieve symptoms (most commonly relievers contain salbutamol). This strategy is vulnerable to poor adherence to maintenance treatment and over-reliance on SABA inhalers, both of which increase airway inflammation and the risk of asthma attack. An alternative strategy using a single fixed-dose inhaler combining ICS with a fast-onset long-acting beta 2-agonist (eg, formoterol) as either anti-inflammatory reliever (AIR) or as maintenance and reliever therapy (MART) is gaining support. In randomised controlled studies as well as pragmatic real-world studies in people with mild to moderate asthma, AIR and MART have been shown to be as effective as standard fixed ICS with as-required SABA and better than SABA-only treatment. Additionally, the Symbicort Turbohaler, th most-studied of the devices licensed for MART/AIR currently, is an inhaled powder device which does not require a spacer and is potentially more environmentally friendly compared with pressurised metered-dose inhaler and metered-dose inhaler devices while being equally effective. Our article aims to review some of the evidence base for AIR/MART in CYP, while giving practical guidance on how to incorporate them into paediatric asthma management.</p>","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":"198-203"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skeletal abnormalities and a low alkaline phosphatase. 骨骼异常，碱性磷酸酶过低。
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-09-18 DOI: 10.1136/archdischild-2024-328144
Catriona Maeve McKay, Noina Abid, Mairead McGinn, Stephanie Whittaker-Axon
{"title":"Skeletal abnormalities and a low alkaline phosphatase.","authors":"Catriona Maeve McKay, Noina Abid, Mairead McGinn, Stephanie Whittaker-Axon","doi":"10.1136/archdischild-2024-328144","DOIUrl":"10.1136/archdischild-2024-328144","url":null,"abstract":"","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":"221-222"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Basic principles of parenteral nutrition for paediatrics and term neonates. 儿科和足月新生儿肠外营养的基本原则。
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-09-18 DOI: 10.1136/archdischild-2024-327715
Emma Wilkinson, Holly Cunningham, Catriona McDonald, Rohini Gite
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引用次数: 0
Fifteen-minute consultation: Talking to children and young people about air pollution. 15分钟咨询：与儿童和青少年讨论空气污染问题。
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-09-18 DOI: 10.1136/archdischild-2024-328307
Harry Apperley, Mark Hayden, Chinthika Piyasena
{"title":"Fifteen-minute consultation: Talking to children and young people about air pollution.","authors":"Harry Apperley, Mark Hayden, Chinthika Piyasena","doi":"10.1136/archdischild-2024-328307","DOIUrl":"10.1136/archdischild-2024-328307","url":null,"abstract":"<p><p>Globally, air pollution is the greatest environmental threat to public health. As well as exacerbating climate change, which continues to degrade population health and economic activity, air pollution has direct health effects that disproportionately impact the most disadvantaged. Air pollution widens inequality, with children's respiratory health, development and well-being shouldering a significant burden. Here, we aim not only to highlight the burgeoning issue of air pollution and its far-reaching impacts on child health, but also to empower and equip clinicians, families and children to intervene in tackling air pollution as part of a local and international agenda.</p>","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":"209-213"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epistle. 书信。
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-09-18 DOI: 10.1136/archdischild-2025-329617
Neelam Gupta
{"title":"Epistle.","authors":"Neelam Gupta","doi":"10.1136/archdischild-2025-329617","DOIUrl":"10.1136/archdischild-2025-329617","url":null,"abstract":"","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":"197"},"PeriodicalIF":0.9,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145066583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to interpret syphilis testing. 如何解读梅毒检测。
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-09-17 DOI: 10.1136/archdischild-2025-329055
Faisal Ali, Sabrina Ye, Kevin Meesters
{"title":"How to interpret syphilis testing.","authors":"Faisal Ali, Sabrina Ye, Kevin Meesters","doi":"10.1136/archdischild-2025-329055","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329055","url":null,"abstract":"<p><p>Rates of syphilis, including congenital syphilis, have been rising worldwide. Syphilis is particularly difficult to diagnose given its non-specific symptoms and the inability to culture <i>Treponema pallidum</i> on regular media. Therefore, various diagnostic methods and complementary testing algorithms have been devised with the aim of accurately diagnosing syphilis. These diagnostic methods include direct detection techniques, useful in diagnosing early primary syphilis before seroconversion, and serological testing divided into treponemal (TT) and non-treponemal (NTT) tests. TTs detect <i>Treponema pallidum</i>-specific antibodies but cannot differentiate active from past infections, while NTT titres correlate with disease activity. In neonates being evaluated for congenital syphilis, maternal antibody transfer complicates this interpretation, necessitating careful correlation with clinical findings and maternal history. We explore these aforementioned tests with cases highlighting how they can be used and interpreted in different clinical scenarios.</p>","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is radiomics? 什么是放射组学？
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-09-09 DOI: 10.1136/archdischild-2024-328347
Timothy Mulvany, Daniel Griffiths-King, Katherine Crombie, Jan Novak, John R Apps
{"title":"What is radiomics?","authors":"Timothy Mulvany, Daniel Griffiths-King, Katherine Crombie, Jan Novak, John R Apps","doi":"10.1136/archdischild-2024-328347","DOIUrl":"https://doi.org/10.1136/archdischild-2024-328347","url":null,"abstract":"","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
If it is not a bruise, what else could it be? 如果不是淤青，还会是什么呢？
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-08-31 DOI: 10.1136/archdischild-2025-329012
Sunanda Bhatia, Nkiru Asiegbunam
{"title":"If it is not a bruise, what else could it be?","authors":"Sunanda Bhatia, Nkiru Asiegbunam","doi":"10.1136/archdischild-2025-329012","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329012","url":null,"abstract":"","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Jaundice in newborn babies under 28 days: NICE guideline 2023 (CG98). 28天以下新生儿黄疸：NICE指南2023 （CG98）。
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-08-31 DOI: 10.1136/archdischild-2025-329317
Jasmine Innerarity, Mailis Michaud Maturana, Joanna Mena, Kamla Pillay, Eva Loucaides, Katie Mckinnon
{"title":"Jaundice in newborn babies under 28 days: NICE guideline 2023 (CG98).","authors":"Jasmine Innerarity, Mailis Michaud Maturana, Joanna Mena, Kamla Pillay, Eva Loucaides, Katie Mckinnon","doi":"10.1136/archdischild-2025-329317","DOIUrl":"https://doi.org/10.1136/archdischild-2025-329317","url":null,"abstract":"","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2025-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What is spatial transcriptomics? 什么是空间转录组学？
IF 0.9 4区 医学
Archives of Disease in Childhood-Education and Practice Edition Pub Date : 2025-08-27 DOI: 10.1136/archdischild-2025-328924
Anne van Kuijk
{"title":"What is spatial transcriptomics?","authors":"Anne van Kuijk","doi":"10.1136/archdischild-2025-328924","DOIUrl":"https://doi.org/10.1136/archdischild-2025-328924","url":null,"abstract":"","PeriodicalId":55471,"journal":{"name":"Archives of Disease in Childhood-Education and Practice Edition","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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