Biofuels Bioproducts & Biorefining-Biofpr最新文献

{"title":"Sustainable levulinic acid production from inulin via hydrothermal conversion","authors":"Gwi-Taek Jeong","doi":"10.1002/bbb.70182","DOIUrl":"https://doi.org/10.1002/bbb.70182","url":null,"abstract":"<p>This study investigates the hydrothermal conversion of inulin using potassium pyrosulfate to levulinic acid (LA). The Box–Behnken design approach was applied to optimize the conversion parameters and analyze the interactions influencing LA yield. Optimal LA yield was obtained at mid-range temperatures in combination with medium to high catalyst concentrations and reaction times. An LA yield of 35.69% was obtained under optimal conditions of 15.3% biomass loading, 1.2 M potassium pyrosulfate at 170 °C for 60 min. Concurrently, formic acid was obtained at a yield of 15.7%, whereas the formations of 5-hydroxymethylfurfural and fructose remained negligible, each yielding below 2%. These results indicate that when used as a feedstock with potassium pyrosulfate, inulin has considerable potential for the sustainable synthesis of high-value platform chemicals.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 5","pages":"2068-2081"},"PeriodicalIF":3.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bbb.70182","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148878376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary insights into zeolite modifications for the conversion of dihydroxyacetone to esters","authors":"Natalia Sobuś,&nbsp;Michał Kiwak,&nbsp;Grzegorz Rotko,&nbsp;Magdalena Król","doi":"10.1002/bbb.70190","DOIUrl":"https://doi.org/10.1002/bbb.70190","url":null,"abstract":"<p>The research investigates the catalytic conversion of dihydroxyacetone (DHA) in alcohol (methanol and ethanol) to obtain organic acid esters. The catalytic materials in this process are modified FAU-type zeolite. The structure was modified using an aqueous NaOH solution and vanadium and molybdenum were incorporated. The catalysts have been characterized in terms of chemical composition, structure acidity, and textural properties. The catalytic tests indicate that the most selective material is the parent material – the hydrogen form of zeolite, which produces methyl lactate with 98.7% selectivity (97.0% yield) during the conversion of DHA in methanol. Ethyl acetate with 94.7% selectivity (89.8% yield) is produced using the vanadium form of zeolite during the conversion of DHA in ethanol.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 5","pages":"2141-2154"},"PeriodicalIF":3.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148878502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical approaches of CO2 conversion into value-added products like methanol and ethanol","authors":"Rima Das","doi":"10.1002/bbb.70181","DOIUrl":"https://doi.org/10.1002/bbb.70181","url":null,"abstract":"<p>The biochemical conversion of gaseous components to produce chemical products is considered a promising alternative when compared to existing techniques. Value-added products such as methanol and ethanol are building block of many chemicals and they are used in the chemical industry as an alternative fuel source, antifreeze, and as precursors of many other compounds. The conversion of the greenhouse gas carbon dioxide (CO₂) into value-added fuels (methanol and ethanol) via biochemical approaches needs to receive more attention in C1 chemistry, as the higher alcoholic products are recognized as fuel additives, reaction solvents, and intermediates. However, this approach is very challenging due to the functional inertness of CO₂. This review summarizes and analyses the recent advances in biocatalytic CO₂ conversion to methanol and ethanol that promise to outperform conventional techniques such as electrochemical or photo-assisted methods. This review gives an overview of the potential sources of CO₂ and its utilization, followed by the current status of methanol and ethanol production and its use. Next, the review focuses on several aspects of the biochemical process that direct conversion of CO₂ to methanol/ethanol enjoys over existing methods. Bacteria-based conversion, especially methanotrophic, acetogenic, and cyanobacteria-based processes, are discussed at length. Algae and enzymes also play an important role in the biochemical conversion of CO₂. Biomass from renewable sources is a promising intermediate product for CO₂ conversion and research efforts are needed to scale up these processes to industrial levels and integrate them into existing infrastructure for large-scale biochemical CO₂ utilization to value-added products.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 5","pages":"1991-2008"},"PeriodicalIF":3.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148878513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Agro and forest wastes valorization: the challenges toward sustainability in biofuels production","authors":"Cintia G. Fit,&nbsp;María C. Area,&nbsp;Nicolás M. Clauser","doi":"10.1002/bbb.70185","DOIUrl":"https://doi.org/10.1002/bbb.70185","url":null,"abstract":"<p>Lignocellulosic biomass is the most abundant biobased raw material worldwide. This category involves agricultural residues, forestry waste, and municipal solid waste. The estimated annual availability of lignocellulosic biomass is between 181 500 and 200 000 million metric tons. From the total, 3.8–4.0% comes from dedicated forest, agricultural, and grass sources, while 2.5–2.6% corresponds to agricultural waste. The availability of this biomass makes biofuels production attractive, representing a promising alternative. Conversion technologies, including thermochemical and biochemical, have demonstrated promising results for biofuels, such as bioethanol, sustainable aviation fuel (SAF), renewable diesel (RD), renewable natural gas (RNG), and hydrogen (H₂). Conversion yields can reach 330 L of bioethanol, up to 250 L of RD, up to 150 kg of SAF and up to 130 kg of H₂ per dry metric ton of biomass, as well as approximately 60% of RNG for each ton of biogas. The projected annual growth rates for biofuels range from 4 to 6% for bioethanol, SAF, and RD and up to 30% for RNG, and are expected to increase exponentially for H₂. Industrial-scale implementation faces several challenges, including seasonal variability, biomass fractionation, and transportation, which in some cases account for up to 50% of the costs. Conversion, fractionation, and enzymes account for approximately 25–30% of operating costs. Current production costs for bioethanol, SAF, and RD range from $0.52 to $0.57 L⁻¹, and can decrease with integration strategies such as byproduct valorization. For hydrogen, it is expected to have a value of $2 kg⁻¹ of H₂ by 2026. Additionally, strategies such as CO₂ capture in biofuel production and the addition of high-value products led to significantly promising results, achieving a notable decrease in environmental impacts. Finally, challenges related to social acceptance and policy support are critical for the long-term success of alternative biofuels.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 5","pages":"2009-2034"},"PeriodicalIF":3.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148878493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Techno-economic evaluation of palm stearin biodiesel production using a continuous deglycerolization reactor","authors":"Kittiphoom Suppalakpanya,&nbsp;Suwattana Nikhom,&nbsp;Nares Chimres,&nbsp;Ruamporn Nikhom","doi":"10.1002/bbb.70176","DOIUrl":"https://doi.org/10.1002/bbb.70176","url":null,"abstract":"<p>The growing reliance on edible oils for biodiesel production raises concerns regarding feedstock availability and cost volatility. Palm stearin (PS), a by-product of palm oil fractionation with reduced demand in food applications, offers an attractive alternative feedstock for biodiesel production. In this study, biodiesel was produced from PS using a continuous deglycerolization reactor (CDR), which removes glycerol during transesterification. The optimal process condition was a methanol–oil molar ratio of 5:1, a potassium methoxide (KOCH₃) catalyst loading of 1.2 wt%, a mixing speed of 250 rpm and a glycerol removal rate of 0.25 L h⁻¹. Under these conditions, the CDR produced high-quality biodiesel with an ester content of 97.23 wt% and a yield of 98 wt%. An economic assessment indicated a positive net present value, an internal rate of return above 8% per year, and a payback period of 1.12 years. Sensitivity analysis showed that economic performance is influenced by production cost and biodiesel selling price, with a break-even selling price of US$0.99 L⁻¹. The combination of reduced methanol consumption and the use of lower-cost PS support the economic viability of the proposed process.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 4","pages":"1963-1974"},"PeriodicalIF":3.8,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative field-scale assessment of TLUD and Kon-Tiki biochar systems: agronomic performance and net CO2e-based techno-economics","authors":"Juan F. Saldarriaga,&nbsp;Thomas Käslin,&nbsp;Enara Fernández,&nbsp;Maider Amutio,&nbsp;Gartzen López,&nbsp;Laura Santamaria,&nbsp;Nausika Querejeta,&nbsp;Julián E. López","doi":"10.1002/bbb.70155","DOIUrl":"https://doi.org/10.1002/bbb.70155","url":null,"abstract":"<p>Post-harvest agricultural residues in Latin America are commonly underutilized, leading to greenhouse gas emissions and lost opportunities for bio-based value creation. This study tests the hypothesis that decentralized, farmer-scale pyrolysis technologies can deliver comparable agronomic benefits while exhibiting distinct techno-economic and climate performance under field conditions. Two biochar production technologies, top-lit up-draft (TLUD) and Kon-Tiki kilns were evaluated using corn cob residues as soil-amending bioproducts at a 1%(w/w) application rate. Both biochars were non-phytotoxic, exhibiting radish germination rates above 90% and no inhibition of radicle elongation. The TLUD biochar developed 21% higher microporosity than Kon-Tiki, indicating enhanced surface functionality for soil–plant interactions. Field application significantly improved soil properties relative to the control, increasing pH by 1.9 units, electrical conductivity by 1.8-fold, organic matter by 1.3-fold, and cation exchange capacity by 1.6-fold. These changes resulted in higher plant nutrient uptake, with foliar potassium and phosphorus concentrations increasing by 1.3- and 1.7-fold, respectively. The TLUD-derived biochar consistently outperformed Kon-Tiki in nutrient delivery, consistent with its higher surface area and fixed-carbon content. Integrating agronomic outcomes with net CO₂e-based techno-economic performance reveals trade-offs between biochar quality, nutrient delivery, capital requirements, and climate benefits that cannot be inferred from laboratory-scale experiments. Techno-economic analysis showed that both technologies generate positive net CO₂e benefits <i>in situ</i>, with TLUD requiring lower initial investment (&gt;900€ less than Kon-Tiki), while both systems converge in profitability after the first production cycle. These findings demonstrate that integrated field-scale assessment is essential to identify decentralized biochar systems that are agronomically effective, economically viable, and climate relevant.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 4","pages":"1762-1780"},"PeriodicalIF":3.8,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bbb.70155","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of pretreatment on VFA production from tofu and tempeh wastewater through anaerobic digestion batch","authors":"Lydia Mawar Ningsih,&nbsp;Mohammad J. Taherzadeh,&nbsp;Steven Wainaina,&nbsp;Hynek Roubík","doi":"10.1002/bbb.70163","DOIUrl":"https://doi.org/10.1002/bbb.70163","url":null,"abstract":"<p>Tofu and tempeh, derived from soybeans, are widely consumed for their nutritional value and high protein content. However, the production of these foods generates nutrient-rich wastewater that poses environmental challenges while offering opportunities for valorization. This study investigates the production of volatile fatty acids (VFAs) and acetic acid from tofu and tempeh wastewater <i>via</i> batch anaerobic digestion, utilizing various pretreatment methods. The pretreatments included adjustment of the pH to 6 and inoculum treatments with and without heat shock under mesophilic and thermophilic conditions. Results demonstrated that the highest average total VFA concentrations of 10.08 and 9.79 g L⁻¹ were achieved for tempeh at T3 (tempeh wastewater + pH 6 + thermophilic + heat shock) and tofu wastewater at TF3 (tofu wastewater + pH 6 + thermophilic + heat shock), respectively. The highest acetic acid concentrations were observed under mesophilic conditions, reaching 77.32% for tempeh wastewater at T7 (tempeh wastewater + unadjusted pH + mesophilic + heat shock) and 92.40% for tofu wastewater at TF10 (tempeh wastewater + pH 6 + mesophilic + non-heat shock). Notably, increased VFA production was associated with reduced cumulative methane yields, such as 3.65 mL g⁻¹ volatle solid (VS) for tempeh at T3 and 25.23 mL g⁻¹-VS for tofu wastewater at TF3. These findings indicate the effectiveness of the pretreatment strategies in enhancing VFA and acetic acid production, suggesting significant potential for industrial applications. Further research is recommended to optimize production processes and explore the broader utilization of VFAs and acetic acid in the bioeconomy, promoting sustainability.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 4","pages":"1743-1761"},"PeriodicalIF":3.8,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bbb.70163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chlorella vulgaris biorefineries: sustainable biofuels and high-value carbon capture","authors":"Sandyelle Ferreira Alcântara Araújo,&nbsp;Antonio Átila Menezes Ferreira,&nbsp;Lucia Andrea Sindeaux de Oliveira,&nbsp;Dayana Nascimento Dari,&nbsp;Devany Quintela Soares,&nbsp;Eliana Elisa Francelino Mavie,&nbsp;Francisco Leonardo Alves de Moraes Sousa,&nbsp;Jessica Lopes da Silva,&nbsp;João Vitor Gomes de Araújo Silva,&nbsp;Thiago Queiroz da Silva,&nbsp;Ana Karine Portela Vasconcelos,&nbsp;Kelma Maria dos Santos Pires Cavalcante,&nbsp;John Hebert da Silva Felix,&nbsp;José Cleiton Sousa dos Santos","doi":"10.1002/bbb.70135","DOIUrl":"https://doi.org/10.1002/bbb.70135","url":null,"abstract":"<p>Global reliance on fossil fuels has created urgent economic and environmental challenges, yet large-scale use of algal biomass remains limited by production costs. Industrial scaling is constrained by inefficient harvesting and the technical challenges of processing recalcitrant cell walls. This review proposes that <i>Chlorella vulgaris</i>-based biorefineries can become economically viable through integrated multiproduct valorization aligned with circular economy principles. A synthesis of literature, patents, and techno-economic studies – supported by bibliometric analyses of the Web of Science and WIPO PATENTSCOPE – highlights multidisciplinary trends spanning biology, engineering, and market dynamics. Academic research primarily focuses on biofuels, whereas patent trends emphasize nutraceutical and cosmetic applications. This divergence reveals opportunities for hybrid cascade-extraction approaches that integrate biotechnology, artificial intelligence-assisted process optimization, and the valorization of residue into biochar. High-value co-products, such as lutein and astaxanthin, support projected profit margins of 40% to 45%, a 3.5- to 4.5-fold increase over biodiesel-only routes, while potentially offsetting up to 4.1 million t CO₂ annually. Future development could include metabolic engineering (e.g., CRISPR/Cas9) to enhance yields, pilot-scale demonstrations in semi-arid regions using brackish water and industrial CO₂ streams, and measures to address regulatory, investor, and certification challenges. Ultimately, <i>C. vulgaris</i>-based biorefineries can foster circular bioeconomies, recover nutrients from waste, and leverage the expanding global market, positioning the species as a versatile and profitable platform for sustainable technological transitions.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 4","pages":"1683-1707"},"PeriodicalIF":3.8,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bbb.70135","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards the development of a biobutanol production process for local fig producers: Nutrient optimization in sequential mesophilic and thermophilic fermentation","authors":"Ebru Özkan,&nbsp;Hidayet Argun","doi":"10.1002/bbb.70177","DOIUrl":"https://doi.org/10.1002/bbb.70177","url":null,"abstract":"<p>This study tests the hypothesis that raw fig waste can be utilized for thermophilic butanol production without pretreatment and that optimizing carbon-to-nitrogen (C/N) and carbon-to-phosphorus (C/P) ratios can enhance fermentation performance. The research is significant for addressing challenges such as food waste valorization, reducing fossil fuel dependency, and contributing to carbon-neutral goals. Economic feasibility is achieved by eliminating costly pretreatment steps and lowering raw material costs. In the mesophilic stage, mixed acidogenic sludge was used for selective butyrate production, followed by butanol synthesis in the thermophilic stage using <i>Thermoanaerobacterium thermosaccharolyticum</i> DSM 571. The effect of external nitrogen and phosphorus supplementation was evaluated using a Box–Wilson experimental design, with C/N (10–400) and C/P (50–2000) ratios as variables. The highest butanol concentration (0.78 g L⁻¹) was obtained at C/N 250 and C/P 950, while the optimum C/N/P ratio was determined as 100/0.4/0.105, increasing butanol production by 30% compared with the control. These findings introduce a new approach in biobutanol production and highlight the industrial potential for integrating agricultural waste into sustainable energy systems.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 4","pages":"1975-1984"},"PeriodicalIF":3.8,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life cycle assessment of biodiesel synthesis from waste cooking oil using bifunctional heterogeneous catalyst","authors":"Frederick Jit Fook Phang,&nbsp;Jocelyn Ling Hui Jong,&nbsp;Michael Toh Yang Wong,&nbsp;Jiuan Jing Chew,&nbsp;Lusi Ernawati,&nbsp;Diah Agustina Puspitasari,&nbsp;Fuping Li,&nbsp;Yen San Chan,&nbsp;Basil T. Wong,&nbsp;Jaka Sunarso","doi":"10.1002/bbb.70165","DOIUrl":"https://doi.org/10.1002/bbb.70165","url":null,"abstract":"<p>The development of renewable energy sources is important in order to achieve the United Nations Sustainable Development Goals (SDGs). Waste cooking oil (WCO) is a promising feedstock for biodiesel production through transesterification. Heterogeneous bifunctional catalysts offer a sustainable alternative to conventional homogeneous bases such as NaOH and KOH. Among them, ferrimagnetic CaO–Fe₃O₄ provides dual acid–base functionality, enabling efficient catalysis with facile magnetic recovery and reuse. This study evaluated the environmental performance of biodiesel synthesis from WCO using homogeneous and heterogeneous catalysts through life cycle assessment (LCA), with biodiesel from virgin cooking oil (VCO) as a benchmark. A cradle-to-gate system boundary was applied, and 10 MJ of biodiesel was defined as the functional unit. Environmental impacts were assessed using midpoint and endpoint indicators. The results showed that electricity consumption was a notable contributor to overall emissions in systems employing heterogeneous catalysts. Sensitivity analysis of the CaO–Fe₃O₄-catalyzed WCO system showed that partial substitution of nonrenewable electricity with 50% renewable electricity reduced climate-change-related emissions by 35%. Overall, the results highlighted the environmental advantages of heterogeneous bifunctional catalysts for WCO biodiesel, particularly when integrated with renewable energy inputs.</p>","PeriodicalId":55380,"journal":{"name":"Biofuels Bioproducts & Biorefining-Biofpr","volume":"20 4","pages":"1882-1894"},"PeriodicalIF":3.8,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bbb.70165","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}