Biopreservation and Biobanking最新文献

{"title":"International Regulatory Harmonization: One World for Human Health.","authors":"Annette Schmid, Marianna Bledsoe","doi":"10.1089/bio.2025.0102","DOIUrl":"https://doi.org/10.1089/bio.2025.0102","url":null,"abstract":"","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Update on the Qualification in Biorepository Science Program at 5 Years.","authors":"Brent Schacter, Daniel Simeon-Dubach","doi":"10.1089/bio.2025.0100","DOIUrl":"https://doi.org/10.1089/bio.2025.0100","url":null,"abstract":"","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ISO/GxP Industrial Facilities with In-House Biobanks to Pursue Accreditation for ISO 20387.","authors":"Daniel Simeon-Dubach, Lotte Marie Glueck, Paul Singh Kalra, Souad Benaouag, Sam Ansari","doi":"10.1089/bio.2024.0149","DOIUrl":"https://doi.org/10.1089/bio.2024.0149","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> The International Organization for Standardization (ISO) standard 20387:2018 outlines general requirements for biobanks to ensure competence, impartiality, and uniform operation. Reasons for seeking ISO 20387 accreditation are improved compliance, international recognition, and increased credibility of a biobank. <b><i>Methods:</i></b> The Philip Morris International (PMI) BioBank is an in-house biobank of an ISO/GxP-driven, for-profit organization. A cross-functional team analyzed ISO 20387 requirements and assessed them against the existing quality management system (QMS) to identify gaps and develop a remediation plan. This allowed the development of an implementation plan with clear timelines. An audit room was reserved for the auditor and PMI BioBank representatives for the two-day audit. In the second room, a group of internal experts were available to answer the auditor's questions, prepare solutions, and bring them to the audit room. <b><i>Results:</i></b> The gap analysis did not reveal any relevant deficits, given that the PMI BioBank follows the corporate QMS mainly based on ISO 17025. However, numerous checklist items require more specific adjustments to the existing QMS. Therefore, a corrective and preventive action (CAPA) was opened to demonstrate that gaps were identified and brought under control during the audit process. Four key areas required documentation employee competencies, complaint management, conduction of risk analysis, and impartiality maintenance. The audit lasted two days. One minor deviation was addressed with a detailed explanation of the process and was accepted by the auditor. <b><i>Conclusions:</i></b> Being part of an ISO/GxP-driven organization allowed the PMI BioBank to go through the ISO 20387 accreditation process rapidly. However, there was a noteworthy need for financial and manpower resources. Still, the benefits of demonstrating highly standardized processes are impactful as they enhance compliance and gain internal and external recognition, credibility, and reputation of an organization.</p>","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Letter:</i> Bridging the Gap: Established Biobanks as Catalysts for Emerging Initiatives.","authors":"Kashif Asghar, Asim Farooq, Linda Hannigan, Fatima M Kafood, Irfan Ahmed","doi":"10.1089/bio.2025.0060","DOIUrl":"https://doi.org/10.1089/bio.2025.0060","url":null,"abstract":"","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do Linalool-Loaded Solid Lipid Nanoparticles Improve the Quality of Naval Medical Research Institute Mouse Sperm During Freezing/Thawing and Handling Processes?","authors":"Zahra Asadi, Faranak Aghaz, Zohreh Rahimi, Elham Arkan, Asad Vaisi-Raygani","doi":"10.1089/bio.2024.0156","DOIUrl":"https://doi.org/10.1089/bio.2024.0156","url":null,"abstract":"<p><p><b><i>Introduction:</i></b> Handling, freezing, and thawing of sperm causes oxidative stress, compromising sperm quality. Nanotechnology offers platforms for the smart delivery of antioxidants during these processes. <b><i>Objectives:</i></b> A solid lipid nanoparticle (SLN) was used to deliver linalool, as an antioxidant supplementation to Naval Medical Research Institute mouse sperm during handling, freezing, and thawing. <b><i>Methods:</i></b> Linalool-loaded solid lipid nanoparticle (L-SLN) was made using the self-assembly method. After the assessment of physicochemical properties, the impact of L-SLN (10, 20, 30, and 50 µg/mL) on sperm motility, viability, sperm DNA fragmentation (SDF), nitric oxide (NO) production, and the activity of superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT), was investigated after its addition to the handling, freezing, and thawing media. <b><i>Results:</i></b> L-SLN was successfully created with a size of 262 ± 9.5 and a zeta potential of -28.5 ± 7.12, with an extended-release over time. During handling and freezing, supplementing corresponding media with L-SLN resulted in increased sperm motility and viability, specifically at 30 µg/mL. The percentage of SDF also decreased in post-thawed sperm at 30 µg/mL. L-SLN also led to elevated post-thawed NO production at 20 µg/mL, as well as increased SOD activity at 20 and 30 µg/mL. It also enhanced CAT and GPx activity at 30 and 10 µg/mL respectively. In handling media, L-SLN at 10 µg/mL could enhance NO production, CAT, and SOD activity, and at 20 µg/mL also boosted NO production and GPx activity. Generally, there was no significant improvement in sperm parameters with the mutual concentration of L-SLN for thawing media. <b><i>Conclusions:</i></b> Treating sperm extender media with 20 and 30 µg/mL of L-SLN and handling media with 10 and 30 µg/mL of L-SLN could improve sperm parameters following these interventions. L-SLN is a new antioxidant for sperm handling and freezing media, which may be applicable in human reproductive efforts.</p>","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Key Recommendations in Promoting Biobanking and Precision Medicine-Dissemination Strategies of the BRoTHER-Biobank Network.","authors":"Lina Winter, Deborah Seidler, Monika Snítilá, Marie Karlíková, Ondrej Topolčan, Ralph Burkhardt, Tanja Niedermair, Christoph Brochhausen","doi":"10.1089/bio.2025.0028","DOIUrl":"https://doi.org/10.1089/bio.2025.0028","url":null,"abstract":"<p><p>Biobanking is essential for advancing precision medicine. However, challenges persist in raising public awareness and addressing data protection concerns. This brief report outlines dissemination strategies by the Central Biobank Regensburg (Zentrale Biobank Regensburg-ZBR) and the BRoTHER (Biobank Research on Telemedical Approaches for Human Biobanks in a European Region) network to engage relevant target groups. In this context, five key recommendations are derived: (1) tailoring communication to audience needs, (2) using diverse outreach methods, (3) enhancing digital presence, (4) fostering cross-border collaboration, and (5) securing dedicated funding. These strategies aim to promote the social and scientific benefits of biobanking while ensuring its sustainability.</p>","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biobanking after Radical Prostatectomy: Comparison of Slice and Punch Protocols.","authors":"Anders Blilie, Guro F Giskeødegård, Åsmund Nybøen, Sebastian Krossa, Elise Midtbust, Einar Gudlaugsson, Ole Gunnar Aasprong, Haakon Skogseth, Jostein Halgunset, Emiel A M Janssen, May-Britt Tessem, Kristin Austlid Taskén","doi":"10.1089/bio.2024.0175","DOIUrl":"https://doi.org/10.1089/bio.2024.0175","url":null,"abstract":"<p><p><b><i>Background:</i></b> Biobanking of prostate cancer tissue is crucial for advancing biomarker-guided precision medicine. However, there is no standardized optimal protocol for biobanking prostatectomy specimens. This study aims to compare the representativeness and sustainability of two biobanking protocols-\"Punch\" and \"Slice\"-currently used in Norway. <b><i>Methods:</i></b> Fresh frozen tissue from 40 radical prostatectomy specimens was biobanked using both the Punch and Slice protocols. Following macroscopic evaluation, a 2 mm thick transverse slice of the prostate (Slice protocol) was collected and stored in an ultra-freezer for future drill biopsy subsampling, guided by histopathological assessment of adjacent formalin-fixed, paraffin-embedded tissue sections. After the slice was collected, five cylindrical tissue samples were punched from the cut surfaces (Punch protocol). Statistical analyses were conducted to compare the sampling precision and time consumption of both protocols. <b><i>Results:</i></b> Cancerous tissue was successfully sampled in 87.5% of cases using the Punch protocol and 75% of cases using the Slice protocol. Both methods yielded comparable results in terms of the number of cancerous cores and the ability to sample tissue representing the highest Gleason grade. The mean biobanking time of tissue slices was 4.9 minutes compared to 15.1 minutes for the ready-to-use tissue punches. Both methods have previously been shown to provide high-quality RNA extracts. <b><i>Conclusion:</i></b> Both biobanking protocols are effective for sampling prostate cancer tissue, with no significant difference in precision or quality. The choice between protocols should consider factors such as resource availability, tissue quantity, and specific research needs. The Punch protocol is less resource-intensive overall, while the Slice protocol collects vastly more tissue, has a shorter period of ischemia, and provides detailed mapping of biobanked components, allowing for further subsampling at multiple time points.</p>","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guideline on Valuation of Research Biospecimen Collections.","authors":"Amanda Rush, Jennifer A Byrne, Peter H Watson","doi":"10.1089/bio.2024.0159","DOIUrl":"https://doi.org/10.1089/bio.2024.0159","url":null,"abstract":"<p><p>Biobanks can consume a lot of financial resources and some biobanks have a poor record of utilization. This suggests the need for better planning by these biobanks around what new biospecimens to collect and store and more deliberate approaches to determine the value of existing biospecimen collections to make operational decisions. Existing biospecimen collections may comprise part of the biobank inventory (where decisions are needed around availability or continued storage) or external collections (where decisions are needed to consider their addition to the inventory). However, there has been limited discussion about how to value these collections. This paper proposes a guideline for the valuation of existing collections based on a two-stage process that involves consideration of features under two broad categories: \"ELSI\" factors and \"Biospecimen and Data\" factors. The first \"initial-valuation\" stage is based on the consideration of five key questions related to each of the main factors and will, in many instances, suffice. This approach can identify salient features of a collection that may have a dominant impact on the value. However, in other instances, a second \"extended-valuation\" stage may be needed to make a more in-depth assessment of the features of a collection. The overall value can then be summarized and/or assigned a score and compared with valuations of comparable collections. The latter might include another collection occupying a similar storage volume within the biobank, a collection from a similar group of donors, or a similar collection stored by another affiliated biobank. In summary, we hope that these guidelines and discussion serve to highlight key factors and an approach to valuing existing collections to improve biobanking efficiency and sustainability.</p>","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usage of the Terms \"Biorepository\" and \"Biobank\": A Process to Achieve a Working Definition Among Global Partners.","authors":"Zoe Steinberg, Judith Giri, Anyela Lozano-Parra, Gustavo Aldopho Gómez, Laura Pezzi, Van-Mai Cao-Lormeau, Md Moyeen Chowdhury, Ibrahim Swaray, Ecaterina Noroc, Elena Romancenco, Inès Vigan-Womas, Ousmane Noël Diallo, Kareen Arias, David Perera, Mong How Ooi, Jajah Fachiroh, Amy Price, Julia Poje, Nikaash Pasnoori, May Chu","doi":"10.1089/bio.2024.0116","DOIUrl":"https://doi.org/10.1089/bio.2024.0116","url":null,"abstract":"","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Ranking Tool for \"Category Killer\" Microbial Biobanks.","authors":"Martin Boutroux, Adriana Chiarelli, Mariana L Ferrari, Olivier Chesneau, Dominique Clermont, Fay Betsou","doi":"10.1089/bio.2024.0027","DOIUrl":"10.1089/bio.2024.0027","url":null,"abstract":"<p><p>Microbial biobanks preserve and provide microbial bioresources for research, training, and quality control purposes. They ensure the conservation of biodiversity, contribute to taxonomical research, and support scientific advancements. Microbial biobanks can cover a wide range of phylogenetic and metabolic diversity (\"category killers\") or focus on specific taxonomic, thematic, or disease areas. The strategic decisions about strain selection for certain applications or for the biobank culling necessitate a method to support prioritization and selection. Here, we propose an unbiased scoring approach based on objective parameters to assess, categorize, and assign priorities among samples in stock in a microbial biobank. We describe the concept of this ranking tool and its application to identify high-priority strains for whole genome sequencing with two main goals: (i) genomic characterization of quality control, reference, and type strains; (ii) genome mining for the discovery of natural products, bioactive and antimicrobial molecules, with focus on human diseases. The general concept of the tool can be useful to any biobank and for any ranking or culling needs.</p>","PeriodicalId":55358,"journal":{"name":"Biopreservation and Biobanking","volume":" ","pages":"127-136"},"PeriodicalIF":1.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}