Biotechnology & Genetic Engineering Reviews最新文献_第6页

Correlation between pure tone audiometry at all frequencies and distortion product otoacoustic emission of patients with hidden hearing loss. 隐性听力损失患者各频率纯音测听与失真产物耳声发射之间的相关性。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-05-12 DOI: 10.1080/02648725.2023.2209408

Yongqing Ding, Yachao Liu, Dong Li, Ruili Hu, Zedong Tian, Qi Xie

{"title":"Correlation between pure tone audiometry at all frequencies and distortion product otoacoustic emission of patients with hidden hearing loss.","authors":"Yongqing Ding, Yachao Liu, Dong Li, Ruili Hu, Zedong Tian, Qi Xie","doi":"10.1080/02648725.2023.2209408","DOIUrl":"10.1080/02648725.2023.2209408","url":null,"abstract":"To explore the correlation between pure tone audiometry at all frequencies and distortion product otoacoustic emission (DPOAE) of hidden hearing loss (HHL). The workers exposed to noise from a factory in Zhangjiakou (noise exposure group, n = 73) and normal young and middle-aged people recruited by society (control group, n = 77) from August 2021 to April 2022 were study subjects, and all of them underwent audiometry in clinic. Compared with the control group, the noise exposure group had significantly higher threshold by extended high-frequency audiometry at all frequencies and higher signal-to-noise ratio threshold (SNR50) (all P < 0.001), and higher amplitude ratio of SP to AP of the waveform induced by short sound at 96, 90, 80 and 70 dB nHL and lower SNR at 6 kHz and above (all P < 0.05). The pure tone audiometry was correlated with DPOAE test results at the frequencies of 6, 8, 9 and 10 kHz (P < 0.001). The results of speech audiometry in noise were related to the average SNR of DPOAE test at each frequency (P = 0.026,r = -0.265). The ratio of SP to AP in electrocochleogram recorded at the intensity of 96 dB nHL was correlated with the average SNR at 6 kHz and above in DPOAE test (P = 0.018,r = -0.461), and with the average auditory threshold at each frequency in extended high-frequency audiometry (P = 0.032, r = 0.421). DPOAE has certain value in detecting HHL.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"4250-4261"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9446684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Based on P (cv-a) CO₂/C (a-cv) O₂ and its changes are associated with an early reduction in multiple organ failure in patients with septic hyperlactocidemia. 基于 P (cv-a) CO2/C (a-cv) O2，其变化与脓毒症高乳酸血症患者多器官衰竭的早期缓解有关。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-05-25 DOI: 10.1080/02648725.2023.2216541

Dan Lv, Changqing Zhu, Keji Zhang

{"title":"Based on P (cv-a) CO2/C (a-cv) O2 and its changes are associated with an early reduction in multiple organ failure in patients with septic hyperlactocidemia.","authors":"Dan Lv, Changqing Zhu, Keji Zhang","doi":"10.1080/02648725.2023.2216541","DOIUrl":"10.1080/02648725.2023.2216541","url":null,"abstract":" The study aimed to investigate the relationship between the respiratory quotient (RQ), measured by the central venous-arterial carbon dioxide partial pressure difference/arterial-venous oxygenation difference ratio, and the early remission of multi-organ failure (MOF) in sepsis patients with hyperlactatemia. The study observed 49 septic patients with hyperlactatemia in the ICU, obtaining blood samples before and after resuscitation, and dividing the patients into two groups depending on whether the modified Sequential Organ Failure Assessment score improved after 24 hours of treatment. Results showed that lactate clearance was faster and the rate of change in RQ was higher in the improved group than in the unimproved group. Further analysis showed that an RQ ≤0.198 mmHg/mL/L or a change of ≥30.71% in RQ after 24 hours of resuscitation was associated with early improvement in MOF. In conclusion, changes in RQ were associated with early improvement in MOF in septic patients with hyperlactatemia, suggesting that RQ could be used as a potential marker for predicting early remission and guiding clinical interventions.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"4784-4797"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Causal relationships between autoimmune diseases and celiac disease: A Mendelian randomization analysis. 自身免疫性疾病与乳糜泻之间的因果关系：孟德尔随机分析

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-05-23 DOI: 10.1080/02648725.2023.2215039

Ting Li, Yan Feng, Chun Wang, Tian Shi, Xiaoling Huang, Mireayi Abuduhadeer, Adilai Abudurexiti, Mengxia Zhang, Feng Gao

{"title":"Causal relationships between autoimmune diseases and celiac disease: A Mendelian randomization analysis.","authors":"Ting Li, Yan Feng, Chun Wang, Tian Shi, Xiaoling Huang, Mireayi Abuduhadeer, Adilai Abudurexiti, Mengxia Zhang, Feng Gao","doi":"10.1080/02648725.2023.2215039","DOIUrl":"10.1080/02648725.2023.2215039","url":null,"abstract":"The aim of this study was to investigate the causal relationship between autoimmune disorders and celiac disease (CeD) through Mendelian randomization (MR). Single nucleotide polymorphisms (SNPs) significantly associated with 13 autoimmune diseases were extracted from the summary statistics of European genome-wide association studies (GWAS), and their effects were examined by Inverse variance-weighted (IVW) in a large European GWAS on CeD. Finally, reverse MR was performed to investigate the causal effects of CeD on autoimmune traits. Following the application of Bonferroni correction for multiple testing, genetically determined seven autoimmune diseases are causally associated with CeD: Crohn's disease (CD) (OR [95%CI] = 1.156 [1.106 ± 1.208], P = 1.27E-10), primary biliary cholangitis (PBC) (1.229 [1.143 ± 1.321], P = 2.53E-08), primary sclerosing cholangitis (PSC) (1.688 [1.466 ± 1.944], P = 3.56E-13), rheumatoid arthritis (RA) (1.231 [1.154 ± 1.313], P = 2.74E-10), systemic lupus erythematosus (SLE) (1.127 [1.081 ± 1.176], P = 2.59E-08), type 1 diabetes (T1D) (1.41 [1.238 ± 1.606], P = 2.24E-07), and asthma (1.414 [1.137 ± 1.758], P = 1.86E-03). The IVW analysis indicated that CeD increased the risk for seven diseases: CD (1.078 [1.044 ± 1.113], P = 3.71E-06), Graves' disease (GD) (1.251 [1.127 ± 1.387], P = 2.34E-05), PSC (1.304 [1.227 ± 1.386], P = 8.56E-18), psoriasis (PsO) (1.12 [1.062 ± 1.182], P = 3.38E-05), SLE (1.301[1.22 ± 1.388], P = 1.25E-15), T1D (1.3[1.228 ± 1.376], P = 1.57E-19), and asthma (1.045 [1.024 ± 1.067], P = 1.82E-05). The sensitivity analyses deemed the results reliable without pleiotropy. There are positive genetic correlations between various autoimmune diseases and CeD, and the latter also affects the predisposition to multiple autoimmune disorders in the European population.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"4611-4626"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9507574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of CECT, CEMRI, and contrast-enhanced ultrasonography in the evaluation of renal cystic lesions: a systematic review and meta-analysis of retrospective studies. CECT、CEMRI 和对比增强超声造影在肾囊肿病变评估中的应用：回顾性研究的系统回顾和荟萃分析。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-05-27 DOI: 10.1080/02648725.2023.2215640

Peipei Feng, Libo Yu, Peng Liang

引用次数: 0

LincRNA PRNCR1 activates the Wnt/β-catenin pathway to drive the deterioration of hepatocellular carcinoma via regulating miR-411-3p/ZEB1 axis. LincRNA PRNCR1通过调控miR-411-3p/ZEB1轴激活Wnt/β-catenin通路，驱动肝细胞癌恶化。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-05-27 DOI: 10.1080/02648725.2023.2216966

Pingsheng Zhou, Yang Liu, Guangzhen Wu, Kai Lu, Teng Zhao, Lixue Yang

{"title":"LincRNA PRNCR1 activates the Wnt/β-catenin pathway to drive the deterioration of hepatocellular carcinoma via regulating miR-411-3p/ZEB1 axis.","authors":"Pingsheng Zhou, Yang Liu, Guangzhen Wu, Kai Lu, Teng Zhao, Lixue Yang","doi":"10.1080/02648725.2023.2216966","DOIUrl":"10.1080/02648725.2023.2216966","url":null,"abstract":"Hepatocellular carcinoma (HCC) is an intractable malignant disease with high incidence rate annually. LincRNA PRNCR1 has been confirmed as a tumor supporter, while its functions in HCC remain unclear. This study aims to explore the mechanism of LincRNA PRNCR1 in hepatocellular carcinoma. The qRT-PCR was applied to the quantification of non-coding RNAs. Cell counting Kit-8 (CCK-8), Transwell assay and flow cytometry assay were applied to reflect the change in the phenotype of HCC cells. Moreover, the databases including Targetscan and Starbase and dual-luciferase reporter assay were applied to investigate the interaction of the genes. The western blot was applied to detect the abundance of proteins and the activity of the related pathways. Elevated LincRNA PRNCR1 was dramatically upregulated in HCC pathological samples and cell lines. MiR-411-3p served as a target of LincRNA PRNCR1, and decreased miR-411-3p was found in the clinical samples and cell lines. LincRNA PRNCR1 downregulation could induce the expression of miR-411-3p, and LincRNA PRNCR1 silence could impede the malignant behaviors via increasing the abundance of miR-411-3p. Zinc finger E-box binding homeobox 1 (ZEB1) was confirmed as a target of miR-411-3p, which remarkably upregulated in HCC cells, and ZEB1 upregulation could significantly rescue the effect of miR-411-3p on malignant behaviors of HCC cells. Moreover, LincRNA PRNCR1 was confirmed to involve the Wnt/β-catenin pathway via regulating miR-411-3p/ZEB1 axis. This study suggested that LincRNA PRNCR1 could drive the malignant progression of HCC via regulating miR-411-3p/ZEB1 axis.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"4809-4824"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9528064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progress in clinical characteristics of high myopia with primary open-angle glaucoma. 高度近视合并原发性开角型青光眼的临床特征研究进展。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-05-27 DOI: 10.1080/02648725.2023.2218765

Yao Lu, Zhi Ji, Jun Jia, Rui Shi, Ying Liu, Qiong Shu, Fulin Lu, Teng Ge, Yuan He

引用次数: 0

Regulation of TREM2 on BV2 inflammation through PI3K/AKT/mTOR pathway. 通过 PI3K/AKT/mTOR 通路调节 TREM2 对 BV2 炎症的影响。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-04-26 DOI: 10.1080/02648725.2023.2204719

Li Li, Qingyou Chen, Yinghui Qin, Guangna Yu, Tingting Qi, Hesong Sui, Xin Qi, Lijuan Huang

{"title":"Regulation of TREM2 on BV2 inflammation through PI3K/AKT/mTOR pathway.","authors":"Li Li, Qingyou Chen, Yinghui Qin, Guangna Yu, Tingting Qi, Hesong Sui, Xin Qi, Lijuan Huang","doi":"10.1080/02648725.2023.2204719","DOIUrl":"10.1080/02648725.2023.2204719","url":null,"abstract":"This work sought to determine how lipopolysaccharide (LPS)-induced pro-inflammatory factor production in BV2 microglia was influenced by myeloid cell 2 (TREM2) expressions. LPS (0.1, 1, and 10 µg/mL) induced inflammation in BV2 cells, MTT and QPCR were used to detect the occurrence of inflammation; TREM2 activation and inhibition vectors were used to activate and inhibit TREM2; Cell Proliferation was detected using CCK-8 and cell cloning experiments. LY294002 was used to inhibit the activity of PI3K/AKT signal pathway; Western blot and ELISA were used to detect cell polarization and signal pathway changes. CCK-8 and cell clone experiments found that the activation of TERM2 can promote the proliferation of BV2 cells; and the activation of TERM2 can promote the expression of IL6, IL1β, TNFα and the expression of M2 cell phenotype molecules Arg-1 and CD206. The effect of adding LY294002 signaling pathway by TERM2 activation was inhibited, indicating that TERM2 can affect the occurrence of inflammation by regulating the activity of PI3K/AKT signaling pathway. Finally, Western blotting and ELISA showed that activation of TERM2 can promote the expression of Arg-1 and CD206 in BV2 cells, and promote the transformation of BV2 cells to M2 polarization. TERM2 can affect the inflammatory response in microglia through the PI3K/AKT signaling pathway, suggesting that TERM2 may be a target for the treatment of inflammatory response in glial cells. This study provides a treatment plan for alleviating the impact of inflammation on central nervous system.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"4040-4061"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9375248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a rapid detection method for enrofloxacin in food. 开发食品中恩诺沙星的快速检测方法。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-04-21 DOI: 10.1080/02648725.2023.2204701

Ning Lu, Meichao Bu, Chao Zhang, Qianni Gao, Xiaolu Wang, Xiaohui Zhou, Dejie Ding, Huimin Zhang

{"title":"Development of a rapid detection method for enrofloxacin in food.","authors":"Ning Lu, Meichao Bu, Chao Zhang, Qianni Gao, Xiaolu Wang, Xiaohui Zhou, Dejie Ding, Huimin Zhang","doi":"10.1080/02648725.2023.2204701","DOIUrl":"10.1080/02648725.2023.2204701","url":null,"abstract":"Develop the ic-ELISA rapid detection method of Enrofloxacin (ENR). Corresponding antibodies are obtained by animal immunity to identify their titer and specificity. The optimal coating time was obtained by indirect competition ELISA, and the antigen coating time, suitable coating concentration, primary antibody dilution factor, blocking solution blocking time, primary antibody reaction time and secondary antibody reaction time were optimized, and the specificity and accuracy of the method were evaluated. The ic-ELISA rapid detection method of ENR, IC50 was 9.13 ng/mL, and the linear detection range (IC20-IC80) was 4.16-20.03 ng/mL. The LOD limit is 2.11 ng/mL. The cross-reactivity rate of 9 fluoroquinolones was above 10%, and the average recovery rate was above 80%. The reason why the heterologous coating is more sensitive may be due to the fact that the piperazine group of ofloxacin is one less carbon atom than enrofloxacin, and ofloxacin is connected to the main ring by N and O hybridization, while enrofloxacin is connected to the main ring through a ternary ring, these two reasons may cause the charge density of extracyclic oxygen at the ofloxacin binding site to be higher than that of enrofloxacin, and the binding ability to antibodies is stronger. Therefore, when heterologous coating, the competitive inhibition rate against enrofloxacin is higher and the effect is better. The conclusion obtained through this experiment is that the detection method has strong broad spectrum and good sensitivity, and can quickly detect the total amount of enrofloxacin and its seven common fluoroquinolones in fish and eggs.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"3931-3949"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9385990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and treatment of tuberculosis presenting as uveitis based on stochastic simulation in systems biology. 基于系统生物学随机模拟对表现为葡萄膜炎的结核病进行诊断和治疗。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-04-26 DOI: 10.1080/02648725.2023.2205197

Li Liu, Yue Gou, Ling Chen, Zhaojing Zong

{"title":"Diagnosis and treatment of tuberculosis presenting as uveitis based on stochastic simulation in systems biology.","authors":"Li Liu, Yue Gou, Ling Chen, Zhaojing Zong","doi":"10.1080/02648725.2023.2205197","DOIUrl":"10.1080/02648725.2023.2205197","url":null,"abstract":"Tuberculous uveitis can be a manifestation of extrapulmonary tuberculosis or an allergic reaction to tuberculosis infection. The clinical signs and symptoms of other uveitis causes are generic, making a false diagnosis simple. We present a brief introduction to theoretical modelling and simulation in systems biology and explore the consequences of TB uveitis if left untreated. Patients were admitted to our hospital with recurrent fever. They had a previous definitive diagnosis of binocular uveitis and a positive interferon gamma release assay (IGRA) test result. At the time, there was no antituberculosis medicine available, and immunosuppressive and glucocorticoid therapy did not work. After the admission, their pleural fluid tested positive for Mycobacterium tuberculosis. No other causes to explain the fever were found. A diagnosis of tuberculosis was made, and their body temperature normalized after antituberculosis treatment and closed chest drainage. Vigilance should be exercised to rule out tuberculous uveitis in cases of unexplained uveitis; this calls for IGRA screening, tuberculin skin testing, and cyst imaging. For patients with latent tuberculosis infections, it is recommended to administer antituberculosis treatment, after excluding other possible causes, and to avoid using glucocorticoids in isolation.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"4098-4107"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9375249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role and mechanism of FTO in pulmonary vessels. FTO 在肺血管中的作用和机制。

IF 6.5 3区工程技术

Biotechnology & Genetic Engineering Reviews Pub Date : 2024-12-01 Epub Date: 2023-05-08 DOI: 10.1080/02648725.2023.2209413

Jing Xu, Dong Yin, Wenjing Zhang, Yi Xu

{"title":"The role and mechanism of FTO in pulmonary vessels.","authors":"Jing Xu, Dong Yin, Wenjing Zhang, Yi Xu","doi":"10.1080/02648725.2023.2209413","DOIUrl":"10.1080/02648725.2023.2209413","url":null,"abstract":"Pulmonary vascular remodeling (PVR) is the main factor of pulmonary hypertension (PH). The pathological characteristics of PVR are vascular smooth muscle hyperplasia, hypertrophy, and extensive damage. In vivo experiments, the expression of FTO in PH rat lung tissues of different rat models of hypoxia PH was observed by immunohistochemical method. mRNA microarray analysis was used to analyze the differential expressed genes in rat lung tissues. In vitro experiments, we developed models of overexpression and knockdown of FTO to study the effect of FTO protein expression on cell apoptotic, cell cycle, and the abundance of m6A. The expression of FTO was increased in PH rats. FTO knockdown can inhibit the proliferation of PASMCs, thereby regulating the cell cycle and reducing the expression of Cyclin D1 and the abundance of m6A, while overexpression of FTO leads to increased expression of Cyclin D1 and the abundance of m6A. FTO destroys the stability of Cyclin D1 by regulating the abundance of Cyclin D1 m6A, causing cell cycle arrest and inducing cell proliferation, thus inducing the occurrence and development of PVR in PH.","PeriodicalId":55355,"journal":{"name":"Biotechnology & Genetic Engineering Reviews","volume":" ","pages":"4284-4299"},"PeriodicalIF":6.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9433534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0