{"title":"Laterality Errors and Risk Reduction Across the Entire Care Pathway at an Ambulatory Day Surgery, 2013-2023.","authors":"Stewart Lake, Carina Mathiasen, Jon Clarke","doi":"10.1111/ceo.14562","DOIUrl":"https://doi.org/10.1111/ceo.14562","url":null,"abstract":"","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric Rozitis, Constantinos Petsoglou, Rajnesh Devasahayam, Scott Hau, Javier Lacorzana
{"title":"Typical Manifestations of the Different Corneal Deposits by In Vivo Confocal Microscopy (IVCM): A Review.","authors":"Eric Rozitis, Constantinos Petsoglou, Rajnesh Devasahayam, Scott Hau, Javier Lacorzana","doi":"10.1111/ceo.14552","DOIUrl":"https://doi.org/10.1111/ceo.14552","url":null,"abstract":"<p><p>In vivo confocal microscopy (IVCM) is a highly useful tool in ophthalmology for investigating a wide range of corneal pathologies. It provides high resolution images with minimal light scattering and is particularly useful in determining the nature of various corneal deposits. Deposits may arise within any layer of the cornea and may occur due to various reasons such as infections (e.g., crystalline deposits), metabolic bodily processes, systemic diseases, pharmacological agents and toxins. Deposits may as a general rule, be linear versus non-linear in shape or hyperreflective or hyporeflective in nature. Non-linear deposits can further be subdivided into granular, round, amorphous, or whorl-like patterns of deposits. This article will attempt to not only summarise all of the currently recognised corneal deposits but also utilise the morphology of the varying types of corneal deposits as seen in IVCM and categorise them within a table.</p>","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144163936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimising the Evaluation of Optic Neuritis YouTube Videos: A Call for Multimedia-Specific Tools and Audience-Oriented Approaches-Response.","authors":"Bedia Kesimal, Sıdıka Gerçeker Demircan, Sücattin İlker Kocamış","doi":"10.1111/ceo.14555","DOIUrl":"https://doi.org/10.1111/ceo.14555","url":null,"abstract":"","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kimberly Spooner, Geoffrey Broadhead, Samantha Fraser-Bell, Thomas Hong, James G Wong, Andrew A Chang
{"title":"Real-World 10-Year Outcomes of Anti-VEGF Therapy for Neovascular Age-Related Macular Degeneration: A Meta-Analysis.","authors":"Kimberly Spooner, Geoffrey Broadhead, Samantha Fraser-Bell, Thomas Hong, James G Wong, Andrew A Chang","doi":"10.1111/ceo.14559","DOIUrl":"https://doi.org/10.1111/ceo.14559","url":null,"abstract":"<p><strong>Background: </strong>This study examines the long-term effectiveness of anti-VEGF therapy in managing neovascular age-related macular degeneration (nAMD). Despite the well-established short-term improvements of anti-VEGF therapy, there is limited data on its continued efficacy over extended periods. This meta-analysis synthesises real-world data to evaluate anti-VEGF therapy's long-term outcomes systematically.</p><p><strong>Methods: </strong>We conducted a comprehensive literature review across PubMed, EMBASE and Cochrane databases, focusing on studies that reported outcomes of anti-VEGF treatment for nAMD over a decade. The analysis included pooling baseline patient characteristics, study designs, sample sizes and changes in visual acuity (VA) over 10 years.</p><p><strong>Results: </strong>Our search produced 12 observational studies encompassing 7509 eyes, with 1274 completing 10-years of follow-up. The most substantial improvement in VA was observed in the first year following the initiation of anti-VEGF therapy. On average, there was a decline of 8.11 letters in VA after 10 years from baseline (95% CI -10.83 to -5.39, p < 0.01). In some cases, VA reverted to baseline levels after 10 years; in others, it declined significantly below baseline. Meta-regression showed that mean VA change was greater in those with a lower baseline VA and those treated with a higher number of injections over 10-years(p < 0.01).</p><p><strong>Conclusion: </strong>Our findings suggest that the mean visual acuity of eyes treated for nAMD deteriorates progressively over the long-term from two years after starting treatment. Regular injections appear crucial for preserving maximum vision. While our analysis did not identify an increased incidence of serious ocular adverse events, the long-term impact of anti-VEGF therapy on geographic atrophy remains unclear and warrants further investigation.</p>","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jascha A Wendelstein, Arianna Grendele, Achim Langenbucher, Alice Galzignato, Catarina Praefke Coutinho, Seth Pantanelli, Kamran M Riaz, Giacomo Savini
{"title":"Normative Values on Stromal Curvature, Power and Corneal-Stromal Curvature Ratios From a Hybrid AS-OCT.","authors":"Jascha A Wendelstein, Arianna Grendele, Achim Langenbucher, Alice Galzignato, Catarina Praefke Coutinho, Seth Pantanelli, Kamran M Riaz, Giacomo Savini","doi":"10.1111/ceo.14556","DOIUrl":"https://doi.org/10.1111/ceo.14556","url":null,"abstract":"<p><strong>Background: </strong>To establish normative values for stromal curvature and its relationships to anterior and posterior curvature.</p><p><strong>Methods: </strong>Retrospective observational study. Data were obtained from 75 eyes of cataract surgery patients using a high-resolution anterior segment optical coherence tomograph (AS-OCT; MS-39, CSO). Data analysis included anterior, stromal, and posterior curvature across multiple zones (1.0-5.0 mm), and derived curvature ratios.</p><p><strong>Results: </strong>The anterior-to-stromal curvature ratio (ASR) remained stable (1.016-1.007), while the stromal-to-posterior (SPR) and anterior-to-posterior (APR) ratios exhibited trends of slight change (SPR: 1.149-1.167; APR: 1.167-1.175). The refractive power analysis revealed incremental effects across one, two, and three refractive surface models, emphasising the importance of integrating posterior and stromal curvature data into optical assessments.</p><p><strong>Conclusion: </strong>This study provides the first normative values for stromal curvature and its ratios with anterior and posterior curvature. These findings may have implications for corneal- and lens-based surgeries and diagnostics.</p>","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Continuing Professional Development","authors":"","doi":"10.1111/ceo.14541","DOIUrl":"10.1111/ceo.14541","url":null,"abstract":"","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":"53 4","pages":"446-448"},"PeriodicalIF":4.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachael C. Heath Jeffery, Ian L. McAllister, Fred K. Chen
{"title":"Real World Data to Improve Outcomes in Retinal Vein Occlusion","authors":"Rachael C. Heath Jeffery, Ian L. McAllister, Fred K. Chen","doi":"10.1111/ceo.14547","DOIUrl":"10.1111/ceo.14547","url":null,"abstract":"","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":"53 4","pages":"342-343"},"PeriodicalIF":4.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytomegalovirus Anterior Uveitis and Endotheliitis: Searching for the Therapeutic Holy Grail","authors":"Luke K. Chehade, Ming Lee Lin","doi":"10.1111/ceo.14546","DOIUrl":"10.1111/ceo.14546","url":null,"abstract":"","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":"53 4","pages":"339-341"},"PeriodicalIF":4.9,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ngozi C. Chidi-Egboka, Leo Fan, Maria Qureshi, Chameen Samarawickrama, Fiona Stapleton, Tanya Trinh, Maria Markoulli, Elsie Chan, Jern Yee Chen, Jason Holland, Stephanie L. Watson
{"title":"Evidence on the Use of Topical Ciclosporin for Ocular Surface Disease: A Systematic Review and Meta-Analysis—Response","authors":"Ngozi C. Chidi-Egboka, Leo Fan, Maria Qureshi, Chameen Samarawickrama, Fiona Stapleton, Tanya Trinh, Maria Markoulli, Elsie Chan, Jern Yee Chen, Jason Holland, Stephanie L. Watson","doi":"10.1111/ceo.14558","DOIUrl":"10.1111/ceo.14558","url":null,"abstract":"","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":"53 6","pages":"730-731"},"PeriodicalIF":5.6,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144113114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zixin Hong, Maryza Graham, Andrew J Daley, Robyn Troutbeck
{"title":"Microbiology and Management of Neonatal Conjunctivitis Presenting to an Urban Australian Paediatric Hospital: An Eight-Year Retrospective Review.","authors":"Zixin Hong, Maryza Graham, Andrew J Daley, Robyn Troutbeck","doi":"10.1111/ceo.14557","DOIUrl":"https://doi.org/10.1111/ceo.14557","url":null,"abstract":"","PeriodicalId":55253,"journal":{"name":"Clinical and Experimental Ophthalmology","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}