Maxence Aubertin, Paolo Perini, Salomé Kuntz, Nabil Chakfe, Anne Lejay
{"title":"Omniflow II Biosynthetic Graft for Infra-inguinal Arterial Reconstruction in Infected Fields: A Systematic Review.","authors":"Maxence Aubertin, Paolo Perini, Salomé Kuntz, Nabil Chakfe, Anne Lejay","doi":"10.1016/j.ejvs.2025.05.040","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.040","url":null,"abstract":"<p><strong>Objective: </strong>This review aimed to evaluate the use of Omniflow II biosynthetic grafts for infra-inguinal vascular reconstruction in infected fields.</p><p><strong>Data sources: </strong>A systematic literature search (Pubmed, Embase, Cochrane Library) following PRISMA guidelines was performed (Prospero registration number CRD420251000785).</p><p><strong>Review methods: </strong>All English full text studies from 1989 - 2024 reporting on infra-inguinal vascular reconstruction using an Omniflow II in an infected field were included. Cases series and cohorts with fewer than five patients were excluded from the pooled analysis. The primary outcome was freedom from re-infection at one year and three years. Secondary outcomes were 30 day all cause mortality, survival, primary and secondary patency, freedom from amputation, and aneurysmal degeneration. Statistical analysis was conducted using Prometa 3.0 and OpenMeta software. Evidence certainty for key outcomes was assessed using GRADE.</p><p><strong>Results: </strong>Six studies (116 patients) were included in the quantitative synthesis. Overall risk of bias was low in four studies and high in two studies. Freedom from re-infection was 90% (95% confidence interval [CI] 82 - 95%) at one year and 76% (95% CI 47 - 92%) at three years. All cause 30 day mortality was 4% (95% CI 0 - 10%). Survival was 93% (95% CI 86 - 97%) at one year and 87% (95% CI 73 - 95%) at three years. Primary patency was 76% (95% CI 66 - 83%) at one year and 68% (95% CI 56 - 77%) at three years. Secondary patency was 83% (95% CI 74 - 89%) at one year and 77% (95% CI 65 - 86%) at three years. Freedom from amputation was 89% (95% CI 82 - 94%) at one year and 88% (95% CI 77 - 94%) at three years. No aneurysmal degeneration was reported. GRADE certainty was low or very low for all outcomes.</p><p><strong>Conclusion: </strong>The Omniflow II graft offers an off the shelf solution for infra-inguinal reconstructions in infected fields when there is no option for autologous vein. Larger prospective cohorts are needed to further validate its effectiveness.</p>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin Qu, Zhaoxiang Zeng, Weixue Huo, Mengwei He, Xianhao Bao, Ye Lu, Wen Tian, Rui Feng
{"title":"Global Burden of Lower Extremity Peripheral Arterial Disease Associated with High Fasting Plasma Glucose: An Analysis of the Global Burden of Disease study 2021.","authors":"Jin Qu, Zhaoxiang Zeng, Weixue Huo, Mengwei He, Xianhao Bao, Ye Lu, Wen Tian, Rui Feng","doi":"10.1016/j.ejvs.2025.05.043","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.043","url":null,"abstract":"<p><strong>Objective: </strong>High fasting plasma glucose (HFPG) is a significant risk factor for lower extremity peripheral arterial disease (PAD). No studies have investigated the detailed global burden of lower extremity PAD associated with HFPG. It is important to evaluate the current epidemiology and changing trends of HFPG related lower extremity PAD.</p><p><strong>Methods: </strong>This study extracted two main indicators from the Global Burden of Disease database, including deaths and disability adjusted life years (DALYs) of lower extremity PAD associated with HFPG from 1990 to 2021. Subanalyses of geographical distribution, sex, age, and sociodemographic index (SDI) were performed, and estimated annual percentage changes were calculated to provide detailed insights into the disease burden.</p><p><strong>Results: </strong>In 2021, there were 25 640 deaths and 562 161 DALYs from lower extremity PAD associated with HFPG worldwide. The global age standardised rates (ASRs) per 100 000 population of deaths and DALYs were 0.32 and 6.73, respectively. The rates of both deaths and DALYs increased with advancing age, peaking in the 95+ years age group, with rates of 31.509 and 292.935 per 100 000, respectively. The rates of deaths and DALYs were, respectively, 0.335 and 7.165 for males and 0.315 and 7.082 for females in 2021. From 1990 to 2021, the ASRs of deaths and DALYs associated with HFPG continued to increase, surpassing those associated with smoking, high body mass index, high systolic blood pressure, and kidney dysfunction.</p><p><strong>Conclusion: </strong>Lower extremity PAD associated with HFPG remains a significant public health concern, with an uneven geographical distribution. The disease burden is higher in high SDI countries and among elderly individuals. Additionally, greater attention should be directed towards females and developing countries, as the burden of PAD associated with HFPG is gradually increasing in these groups and countries.</p>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intra-operative Retrograde Type A Dissection During Fenestrated Endovascular Aortic Repair.","authors":"Lutong Yan, Zhihui Dong","doi":"10.1016/j.ejvs.2025.05.041","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.041","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Burn It To The Ground.","authors":"Chrysanthi P Papageorgopoulou, Stavros K Kakkos","doi":"10.1016/j.ejvs.2025.05.039","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.039","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Lessons from the Tragedy of War Advance Civilian Vascular Surgery.","authors":"Carl Magnus Wahlgren, Pirkka Vikatmaa","doi":"10.1016/j.ejvs.2025.05.037","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.037","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seeking Clarity in the Muddy Waters of Vasculo-Behçet Management.","authors":"Rahul Agarwal, Prem C Gupta","doi":"10.1016/j.ejvs.2025.05.017","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.017","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Prognosis in Chronic Limb Threatening after Revascularisation Versus Non-revascularisation Treatment: Analysis of Japanese Regional Insurance Claims.","authors":"Tsunehiro Shintani, Eiji Nakatani, Hideaki Kaneda, Philip Hawke, Hideaki Obara, Takeshi Usui","doi":"10.1016/j.ejvs.2025.05.036","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.036","url":null,"abstract":"<p><strong>Objective: </strong>While the prevailing practice for treating chronic limb threatening ischaemia (CLTI) is revascularisation, we have a limited understanding of disease progression in patients with CLTI who do not undergo this intervention. This study compared the prognosis of CLTI patients with tissue loss who underwent revascularisation with the prognosis of those who were managed with non-revascularisation treatment, investigating the efficacy of revascularisation in improving the outcome of CLTI patients.</p><p><strong>Methods: </strong>Utilising the Shizuoka Kokuho Database, a regionally representative longitudinal cohort in Japan, this retrospective analysis examined CLTI patients with tissue loss (ulcer and gangrene), between April 2012 and September 2020, identifying two distinct cohorts: those receiving non-revascularisation treatment and those undergoing revascularisation. The primary endpoint was amputation free survival, evaluated in both cohorts after applying post-propensity score matching.</p><p><strong>Results: </strong>Of the 3 160 CLTI patients with tissue loss, 559 received non-revascularisation treatment, and 589 underwent revascularisation. The non-revascularisation treatment predominantly involved prostaglandin E1 injections (99.1%). After one to one propensity score matching, the revascularisation cohort (372 patients) exhibited a markedly enhanced amputation free survival rate compared with their non-revascularisation counterparts (amputation free survival rate at one year: 58.0% vs. 45.7%, p = .014). Subgroup analyses underscored the greater efficacy of revascularisation across multiple categories, including male (hazard ratio [HR] 0.59, 95% confidence interval (CI) 0.47 - 0.75), diabetes mellitus (HR 0.67, 95% CI 0.50 - 0.89), and patients with severe wounds (HR 0.76, 95% CI 0.61 - 0.93). However, the analysis did not find differences between the revascularisation and non-revascularisation treatment groups among female patients (HR 1.06, 95% CI 0.78 - 1.45) and patients with non-severe wounds (HR 0.87, 95% CI 0.58 - 1.30).</p><p><strong>Conclusion: </strong>This regional Japanese cohort study reveals a potential enhancement in the amputation free survival rate post-revascularisation for CLTI patients with tissue loss compared with non-revascularisation treatment, except in female patients and patients with non-severe wounds. Additional studies are needed to further elucidate these results.</p>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myeonghyeon Ko, Chanjoong Choi, Ahram Han, Sanghyun Ahn, Kyung-HwaKim, Hwan Jun Jae, Eun Bong Lee, Seung-Kee Min
{"title":"Long Term Outcomes of Open or Endovascular Treatment for Arterial Manifestations in Behçet Disease.","authors":"Myeonghyeon Ko, Chanjoong Choi, Ahram Han, Sanghyun Ahn, Kyung-HwaKim, Hwan Jun Jae, Eun Bong Lee, Seung-Kee Min","doi":"10.1016/j.ejvs.2025.05.035","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.035","url":null,"abstract":"<p><strong>Objective: </strong>Behçet disease (BD) is a rare multisystemic disorder with occasional involvement of large vessels. While many patients with BD are managed medically, arterial manifestations often necessitate surgical or endovascular intervention. This study aims to analyse invasively treated arterial involvement in BD and identify risk factors for recurrent re-interventions.</p><p><strong>Methods: </strong>A retrospective review from January 1990 to December 2020 included 30 patients who underwent 54 surgeries for arterial BD. Initial operations were categorised as open or endovascular. Demographic data, arterial lesions, causes of operations, pre-operative medications, re-operation rates, and death were assessed. Re-operations were classified by surgery type and lesion site. Analytical methods encompassed comparisons of graft materials, laboratory findings, and the International Criteria for BD (ICBD).</p><p><strong>Results: </strong>Index procedures involved 21 open surgeries and nine endovascular interventions. Median age was 39 years, and 77% were male. Mainly involved arteries were the abdominal aorta (ten cases), peripheral arteries (14 cases), and visceral artery (one case). Arterial manifestations included intact aneurysms (20 cases), ruptured aneurysms (six cases), and thrombotic occlusions or stenosis (four cases). Abdominal aortic diseases were treated mainly by endovascular interventions; otherwise, open and endovascular groups showed similar demographics. Re-operations were performed in 40% of cases, demonstrating a significant association with ICBD score (p = .004). An ICBD score of ≥ 6 points showed 4.8 times higher risk of re-intervention.</p><p><strong>Conclusion: </strong>Arterial manifestations in BD often mandate surgical intervention, with a notable proportion requiring multiple re-operations. No discernible differences were found between open and endovascular approaches, but a higher ICBD score emerged as a risk factor for re-operation.</p>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victor Bilman, Abebe Tiruneh, Daniel Silverberg, Ruth Skvortsov, Eldad Katorza, Moshe Halak
{"title":"Preliminary Assessment of Contemporary Wartime Vascular Injuries.","authors":"Victor Bilman, Abebe Tiruneh, Daniel Silverberg, Ruth Skvortsov, Eldad Katorza, Moshe Halak","doi":"10.1016/j.ejvs.2025.05.031","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.05.031","url":null,"abstract":"<p><strong>Objective: </strong>Vascular trauma during military conflicts, often from blasts and high velocity gunshots, is a major challenge in vascular surgery. Advances in vascular surgery have improved wartime injury management. This study evaluated vascular injury patterns and key risk factors for death and amputation in a recent conflict.</p><p><strong>Methods: </strong>This retrospective study analysed vascular injuries in hospitalised soldiers from a recent conflict using National Trauma Registry data. Primary outcomes were major amputation and death. Descriptive statistics and logistic regression were used for data analysis, following the STrengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement.</p><p><strong>Results: </strong>From 7 October 2023 to 31 May 2024, a total of 2 040 Israeli soldiers (1 990 male, 97.5%; mean age 25 ± 6.9 years, median age [interquartile range, IQR] 23 [20, 28] years) were treated for injuries sustained in a recent military conflict. Among them, 179 cases (9.0%; 176 male, 98.3%; mean age 25 ± 7.19 years) were identified as vascular casualties. A total of 218 vascular injuries (in these 179 patients) were reported, with lower extremities being the most affected region (112 of 218 vessels, 51.4%). The median time from injury to trauma centre arrival was 66 minutes and from the emergency department to surgery was 76 minutes (IQR 37, 330 minutes). In 136 patients, 161 vascular procedures were performed, mainly primary repair ± patch angioplasty (31.7%) and bypass (26.7%). Secondary amputation occurred in 10 of 179 (5.6%) cases, with an overall mortality rate of 8.9% (n = 16 of 179). Multivariate analysis found high Injury Severity Scores (odds ratio [OR] 1.08; 95% confidence interval [CI] 1.02 - 1.17; p = .016), systolic blood pressure < 90 mmHg at admission (OR 24.39; 95% CI 3.38 - 254.49; p =.003), and thoracic vessel injury (OR 15.23; 95% CI 1.68 - 177.04; p = .017) as risk factors for death. Lower extremity fractures (OR 6.51; 95% CI 1.35 - 49.01; p = .032) predicted lower extremity secondary amputation.</p><p><strong>Conclusion: </strong>This study highlights the characteristics of vascular injuries in modern warfare, identifying higher mortality rates with thoracic vessel injuries, shock at admission, and high Injury Severity Scores, while secondary amputation correlates with lower extremity fractures.</p>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144120385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}