European Journal of Vascular and Endovascular Surgery最新文献

{"title":"There Is No Light Without Shadow.","authors":"Raphaël Coscas, Jos C van den Berg","doi":"10.1016/j.ejvs.2025.03.036","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.03.036","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic Occlusion and Mesenteric Ischaemia: Radial Access at Hand.","authors":"Henrique Andrade Almeida, Carlos Veterano","doi":"10.1016/j.ejvs.2025.03.027","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.03.027","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Management of Tumours Invading the Inferior Vena Cava: A Delphi Consensus Document.","authors":"Peter Balaz, Adam Whitley, Ivika Heinola, Mauro Gargiulo, Pirkka Vikatmaa","doi":"10.1016/j.ejvs.2025.03.034","DOIUrl":"https://doi.org/10.1016/j.ejvs.2025.03.034","url":null,"abstract":"<p><strong>Objective: </strong>There is a lack of information and consistency in the treatment of retroperitoneal malignancy involving the inferior vena cava (IVC). The aim of this study was to establish an expert consensus on the surgical management of tumours involving the IVC.</p><p><strong>Methods: </strong>Fourteen experts participated in this three round Delphi project. The survey was conducted from 1 January 2023 to 15 December 2023. Consensus was defined as 70% agreement with a Cronbach's α of 0.05.</p><p><strong>Results: </strong>All experts completed the first round, and the response rates in the second and third rounds were 92% and 86%, respectively. Consensus was reached on several key points. Abdominal computed tomography (CT) was identified as the gold standard imaging method for assessing tumours invading the IVC. CT guided core needle biopsy was preferred for tissue sampling. Experts agreed that the suprarenal IVC should be reconstructed, whereas a chronically occluded IVC with intact collateral circulation should not. Thrombectomy was indicated for malignant thrombi not involving the vessel wall; otherwise, IVC resection was recommended. A ringed ePTFE (expanded polytetrafluoroethylene) prosthesis was the preferred graft material for interposition. Use of an IVC filter to prevent tumour embolisation and the creation of an arteriovenous fistula after IVC resection were not recommended. Post-operative thrombosis prevention should include therapeutic heparinisation and a mechanical compression device, and routine post-operative CT angiography was recommended.</p><p><strong>Conclusion: </strong>Based on scarce data from the literature and experience of international experts, this document will help clinicians in the decision making process when planning the treatment of retroperitoneal tumours involving the IVC.</p>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":" ","pages":""},"PeriodicalIF":5.7,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editor's Choice – Outcomes of Endovascular Repair Confined to the Ascending Thoracic Aorta: A Systematic Review and Meta-Analysis","authors":"Jasper F. de Kort ,&nbsp;Tim J. Mandigers ,&nbsp;Daniele Bissacco ,&nbsp;Maurizio Domanin ,&nbsp;Gabriele Piffaretti ,&nbsp;Christopher P. Twine ,&nbsp;Anders Wanhainen ,&nbsp;Joost A. van Herwaarden ,&nbsp;Santi Trimarchi ,&nbsp;Carlo de Vincentiis","doi":"10.1016/j.ejvs.2024.10.049","DOIUrl":"10.1016/j.ejvs.2024.10.049","url":null,"abstract":"<div><h3>Objective</h3><div>High risk, inoperable patients with ascending aortic disease are increasingly managed with thoracic endovascular aortic repair (TEVAR). The aim of this study was to assess the available literature on TEVAR confined to the ascending aorta (a-TEVAR), describing study and patient characteristics, procedural and stent graft details, and outcomes.</div></div><div><h3>Data sources</h3><div>This was a systematic review and meta-analysis. MEDLINE, Web of Science, and Scopus were systematically searched for eligible studies reporting on outcomes after a-TEVAR (PROSPERO ID: CRD42023440826). Eligible studies reported outcomes after a-TEVAR without adjunctive supra-aortic vessel treatment.</div></div><div><h3>Review Methods</h3><div>The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was followed. The ROBINS-I and Joanna Briggs Institute Critical Appraisal Checklist were used as quality assessment tools. A Grading of Recommendations Assessment, Development, and Evaluation (GRADE) evidence certainty analysis was performed for the main outcomes. The main outcome was death. A proportional meta-analysis was performed with a mean and 95% confidence interval (CI) for the main outcomes. All articles were included up to 1 January 2024.</div></div><div><h3>Results</h3><div>Ninety four studies were included (19 cohort studies, 75 case reports or series), reporting on 259 patients (57.8% male). The mean age was 69.1 (95% CI 65.0 – 73.1) years and mean follow up 19.6 (95% CI 14.5 – 24.6) months. The most common comorbidity was prior cardiac or thoracic surgery (<em>n</em> = 191). The most frequent indications for a-TEVAR (52.1% urgent a-TEVAR) were type A aortic dissection (43.6%) and pseudoaneurysm (38.6%). The most commonly deployed stent grafts were Gore (44.5%), Cook (23.5%), and Medtronic (17.0%). The in hospital mortality rate was 7.3% (95% CI 4.7 – 11.2%), 30 day mortality rate 7.7% (95% CI 5.1 – 11.6%), and overall mortality rate 17.0% (95% CI 12.9 – 22.0%) during follow up. GRADE showed very low evidence certainty for all outcomes. Eighty eight complications were reported and there was a re-operation rate of 13.1% (95% CI 9.5 – 17.8%). In hospital and 30 day mortality rates for type A dissection were 12.4% (95% CI 7.5 – 19.7%) (<em>n</em> = 14) and 13.3% (95% CI 8.2 – 20.8%) (<em>n</em> = 15), respectively, and for pseudoaneurysm 4.0% (95% CI 1.6 – 9.8%) (<em>n</em> = 4) and 4.0% (95% CI 1.6 – 9.8) (<em>n</em> = 4), respectively.</div></div><div><h3>Conclusion</h3><div>Despite heterogeneous literature and very low GRADE evidence certainty, a-TEVAR seems technically feasible in high risk patients. In addition, there is need for a consensus on when and how to use a-TEVAR and a need for a specific endograft for use in the ascending aorta.</div></div>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":"69 4","pages":"Pages 531-544"},"PeriodicalIF":5.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standards for Abdominal Aortic Aneurysm Repair Quality Improvement Registries: A Delphi Consensus Report From VASCUNET and the International Consortium of Vascular Registries","authors":"Matthew Joe Grima ,&nbsp;Stefano Ancetti ,&nbsp;Arun D. Pherwani ,&nbsp;Frederico B. Gonçalves ,&nbsp;Jacob Budtz-Lilly ,&nbsp;Christian-Alexander Behrendt ,&nbsp;Salvatore T. Scali ,&nbsp;Adam W. Beck ,&nbsp;Kevin Mani","doi":"10.1016/j.ejvs.2024.12.002","DOIUrl":"10.1016/j.ejvs.2024.12.002","url":null,"abstract":"<div><h3>Objective</h3><div>Outcome registries in vascular surgery are used increasingly to drive quality improvement by vascular societies. The VASCUNET collaboration, within the European Society for Vascular Surgery (ESVS), and the International Consortium of Vascular Registries (ICVR) developed a set of variables for quality improvement registries on abdominal aortic aneurysm (AAA) repair as a registry standard.</div></div><div><h3>Methods</h3><div>Representatives from international vascular registries within VASCUNET, ICVR, and other nations with established registries were invited to provide the variables. The final variables were developed through a two stage modified Delphi process. Variables from the established registries with at least 60% consensus among all the registries were included for round 1. A five point Likert scale (strongly disagree to fully agree) was used. If the limit of consensual agreement was not reached in round 1, the variable was discussed again in round 2. For round 2, an array question method (yes, no to unsure) was used. Agreement of at least 70% resulted in the variable being included in the final dataset.</div></div><div><h3>Results</h3><div>A total of 88 of 371 variables extracted from all AAA registries were circulated in the modified Delphi process as they reached the 60% consensus threshold. The questionnaire was circulated to 55 participants (round 1: 49; 89%; round 2: 43; 78%). After two rounds, 70 variables were recommended on consensual agreement. These variables comprised demographics (<em>n</em> = 4), pre-operative information (<em>n</em> = 28), intra-operative variables (<em>n</em> = 18), post-operative variables (<em>n</em> = 5), and follow up (<em>n</em> = 13).</div></div><div><h3>Conclusion</h3><div>Based on this modified Delphi process, an international panel of vascular surgeons representing quality improvement registries recommended 70 core variables as standard in AAA repair registries. The inclusion of a core set of variables in AAA vascular registries may help to further harmonise observational research and quality of AAA repair among global healthcare systems.</div></div>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":"69 4","pages":"Pages 516-521"},"PeriodicalIF":5.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Sac Thrombus Good or Bad for Complex Endovascular Aneurysm Repair?","authors":"Harm P. Ebben ,&nbsp;Christos D. Karkos","doi":"10.1016/j.ejvs.2025.01.036","DOIUrl":"10.1016/j.ejvs.2025.01.036","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":"69 4","pages":"Page 576"},"PeriodicalIF":5.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age effect in asymptomatic carotid stenosis in the CREST and ACT 1 stenting vs endarterectomy trials","authors":"Jenifer H. Voeks PhD ,&nbsp;Bret Hanlon PhD ,&nbsp;Thomas G. Brott MD ,&nbsp;Jon S. Matsumura MD ,&nbsp;Ken Rosenfield MD ,&nbsp;Gary S. Roubin MD, PhD ,&nbsp;George Howard DrPH ,&nbsp;CREST and ACT 1 Investigators","doi":"10.1016/j.ejvs.2025.02.052","DOIUrl":"10.1016/j.ejvs.2025.02.052","url":null,"abstract":"","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":"69 4","pages":"Pages e261-e262"},"PeriodicalIF":5.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Aortic Thrombus on Outcomes Following Repair of Juxtarenal Aneurysms Using Physician Modified Endografts","authors":"Chase Nelson ,&nbsp;Gerald Anderson ,&nbsp;Allison Larimore ,&nbsp;Kirsten D. Dansey ,&nbsp;Benjamin W. Starnes ,&nbsp;Sara L. Zettervall","doi":"10.1016/j.ejvs.2024.10.035","DOIUrl":"10.1016/j.ejvs.2024.10.035","url":null,"abstract":"<div><h3>Objective</h3><div>Studies have suggested that aortic thrombus may be associated with adverse outcomes following endovascular repair of aortic aneurysms, while other reports have suggested higher rates of sac regression and a reduced risk of endoleak. However, the effect of thrombus burden on outcomes following physician modified endografts (PMEGs) remains unknown. This study aimed to assess the volume and morphology of thrombus burden and the effect on outcomes following PMEG for juxtarenal abdominal aortic aneurysm.</div></div><div><h3>Methods</h3><div>This was a retrospective cohort study of patients who underwent PMEG from 2009 to 2021 in a single centre, investigational device exemption trial. Thrombus burden was measured as a percentage of luminal volume using pre-operative computed tomography scans from the lowest renal artery to the level of the aortic bifurcation using centreline reconstruction software. Morphology was documented by the presence of finger like projections. Univariable and multivariable analyses evaluated the impact on peri-operative and long term outcomes.</div></div><div><h3>Results</h3><div>Volumetric and morphological measures of thrombus burden were assessed in 142 patients; 40.1% of the cohort were classified as having a high thrombus burden (≥ 50% luminal volume) on volumetric assessment and 22.5% had finger like projections on morphological assessment. Type II endoleak was more frequently observed in those with low thrombus burden (60.0% <em>vs.</em> 33.3%; <em>p</em> = .008) and persisted after multivariable analysis (odds ratio 2.5, 95% confidence interval 1.1 – 5.8), but there were no other statistically significant differences in peri-operative adverse events or late outcomes, including sac behaviour, freedom from re-intervention, and overall survival when stratifying thrombus burden by quantitative or qualitative measures. There were no observed differences in operative or anatomical characteristics, including landing zone characteristics and rates of inferior mesenteric artery patency.</div></div><div><h3>Conclusion</h3><div>While thrombus burden and morphology were not associated with adverse peri-operative events or survival, low thrombus burden was associated with an increase in type II endoleak. These findings suggest that thrombus burden should not deter treatment for patients requiring PMEG.</div></div>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":"69 4","pages":"Pages 568-575"},"PeriodicalIF":5.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review and Meta-analysis of Outcomes of the Advanta V12 or iCAST Bridging Stent Graft Used for Fenestrated and Branched Endovascular Aortic Repair","authors":"Petroula Nana ,&nbsp;Konstantinos Dakis ,&nbsp;Alexandros Brodis ,&nbsp;José I. Torrealba ,&nbsp;Giuseppe Panuccio ,&nbsp;Konstantinos Spanos ,&nbsp;Tilo Kölbel","doi":"10.1016/j.ejvs.2025.01.004","DOIUrl":"10.1016/j.ejvs.2025.01.004","url":null,"abstract":"<div><h3>Objective</h3><div>Half of re-interventions after fenestrated and branched endovascular aortic repair (FB-EVAR) are target vessel related. Regarding bridging stent choice, existing data are controversial. This meta-analysis aimed to evaluate the performance of Advanta V12/iCAST as the bridging stent in FB-EVAR.</div></div><div><h3>Data Sources</h3><div>The English medical literature was searched through MEDLINE, Embase (via Ovid), and Cochrane databases (end date 15 April 2024).</div></div><div><h3>Review Methods</h3><div>The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines and PICO (Patient, Intervention, Comparison, Outcome) model were followed. A predefined protocol was registered to PROSPERO (CRD42024556603). Randomised controlled trials and observational studies (2010 – 2024) reporting on Advanta V12/iCAST related target vessel outcomes were eligible. Risk of bias was assessed using ROBINS-I, and evidence quality was assessed via Grading of Recommendations Assessment, Development and Evaluations (GRADE). Primary outcomes were freedom from instability, stenosis and or occlusion, types Ic and IIIc endoleak, and re-intervention of target vessels bridged with the Advanta V12/iCAST. Prevalence and regression meta-analysis were performed.</div></div><div><h3>Results</h3><div>From 1 439 articles, ten retrospective studies (7 525 target vessels; 3 890 target vessels bridged with Advanta V12/iCAST) were included. According to ROBINS-I, no study was of high quality. Mean follow up was 24.3 (95% confidence interval [CI] 23.9 – 24.7) months. Freedom from instability, stenosis and or occlusion, and types Ic and IIIc endoleak were 94% (95% CI 91 – 96%; <em>p</em> &lt; .010; <em>I</em>² = 91%; GRADE certainty, very low), 97% (95% CI 96 – 98%; <em>p</em> =  .070, <em>I</em>² = 44%; GRADE certainty, low), and 97% (95% CI 94 – 98%; <em>p</em> &lt; .010; <em>I</em>² = 81%; GRADE certainty, very low), respectively. Freedom from target vessel re-intervention was 95% (95% CI 92 – 97%; <em>p</em> &lt; .010; <em>I</em>² = 85%; GRADE certainty, very low). Four studies provided extractable data on Advanta V12/iCAST in fenestrations and four in branches. No difference was detected in freedom from instability (<em>p</em> = .47), stenosis and or occlusion (<em>p</em> = .36), and types Ic and IIIc endoleak (<em>p</em> = .90). Freedom from re-intervention was 93% (95% CI 87 – 96%; <em>p</em> &lt; .010; <em>I</em>² = 90%) in fenestrations and 95% (95% CI 91 – 97%; <em>p</em> = .060, <em>I</em>² = 64%) in branches.</div></div><div><h3>Conclusion</h3><div>The Advanta V12/iCAST bridging stent showed high freedom from target vessel instability, stenosis and or occlusion, and endoleak. Freedom from re-intervention was 95%, being similarly high in fenestrations and branches.</div></div>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":"69 4","pages":"Pages 547-559"},"PeriodicalIF":5.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kidney Function, Kidney Function Decline, and the Risk of Abdominal Aortic Aneurysm: The Stockholm CREAtinine Measurements (SCREAM) Project","authors":"Shigeru Tanaka ,&nbsp;Alessandro Bosi ,&nbsp;Edouard L. Fu ,&nbsp;Kunitoshi Iseki ,&nbsp;Takanari Kitazono ,&nbsp;Rebecka Hultgren ,&nbsp;Anne-Laure Faucon ,&nbsp;Juan-Jesus Carrero","doi":"10.1016/j.ejvs.2024.12.026","DOIUrl":"10.1016/j.ejvs.2024.12.026","url":null,"abstract":"<div><h3>Objective</h3><div>Low estimated glomerular filtration rate (eGFR) increases the risk of arterial diseases, possibly including abdominal aortic aneurysm (AAA). This study explored the relationship between eGFR (2008 CKD-EPI equation), annual eGFR decline, and subsequent risk of developing AAA in a large, community based sample.</div></div><div><h3>Methods</h3><div>This was an observational study using complete healthcare records of Stockholm residents free from AAA who underwent routine creatinine testing during 2011 – 2021. Cox regression, adjusted for age, sex, comorbidities, and ongoing medications, was used to analyse the association between a single point eGFR or the change in eGFR within a year and the rate of both a <em>de novo</em> AAA diagnosis (both intact and ruptured) and fatal AAA (i.e., AAA followed by death within 30 days).</div></div><div><h3>Results</h3><div>The study included 1 586 410 participants (mean age 48 years; 53% female; median eGFR 96 mL/min/1.73 m²). During a median follow up of 7.6 years, 5 313 participants (0.34%) experienced AAA, of which 321 (0.02%) were fatal. In multivariable analyses, compared with eGFR 90 mL/min/1.73 m², the rates of AAA events were higher across lower eGFRs: for eGFR 30 mL/min/1.73 m², the hazard ratio (HR) of AAA was 1.24 (95% confidence interval [CI] 1.09 – 1.40) and of fatal AAA was 2.51 (95% CI 1.67 – 3.75); for eGFR 15 mL/min/1.73 m², the HR of AAA was 1.49 (95% CI 1.19 – 1.86) and of fatal AAA was 3.73 (95% CI 2.04 – 6.81). When analysed separately, the results were similar for intact and ruptured AAA risk. Among the 638 959 participants who had repeated eGFR tests, 3 447 (0.54%) experienced AAA events, of which 217 (0.04%) were fatal. Compared with stable eGFR (change –1 to 1 mL/min/year), the rate of AAA events was 15% higher (HR 1.15, 95% CI 1.05 – 1.26) in participants with an eGFR decline of 1 to 3 mL/min/year and 46% higher (HR 1.46, 95% CI 1.16 – 1.84) in those with an eGFR decline of &gt; 3 mL/min/year.</div></div><div><h3>Conclusion</h3><div>In this observational study, both a single point eGFR and a faster eGFR decline were associated with the risk of experiencing AAA. The incidence of AAA, and particularly fatal AAA, was higher in individuals with greater severity of chronic kidney disease or faster eGFR decline.</div></div>","PeriodicalId":55160,"journal":{"name":"European Journal of Vascular and Endovascular Surgery","volume":"69 4","pages":"Pages 601-608"},"PeriodicalIF":5.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}