Gold Bulletin最新文献_第3页

Synergic effect of paclitaxel and cisplatin associated with gold nanoparticles on HeLa cervical cells 紫杉醇和顺铂联合金纳米颗粒对HeLa宫颈细胞的协同作用

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-01-22 DOI: 10.1007/s13404-021-00305-5

Maria Laura Rodrigues Uggioni, Paulo Emilio Feuser, Jonathann Corrêa Possato, Maria Eduarda de Melo, Ellen De Pieri, Rodrigo Cercena, Alexandre Gonçalves Dal Bó, Maria Inês da Rosa, Ricardo Andrez Machado-de-Ávila

{"title":"Synergic effect of paclitaxel and cisplatin associated with gold nanoparticles on HeLa cervical cells","authors":"Maria Laura Rodrigues Uggioni, Paulo Emilio Feuser, Jonathann Corrêa Possato, Maria Eduarda de Melo, Ellen De Pieri, Rodrigo Cercena, Alexandre Gonçalves Dal Bó, Maria Inês da Rosa, Ricardo Andrez Machado-de-Ávila","doi":"10.1007/s13404-021-00305-5","DOIUrl":"10.1007/s13404-021-00305-5","url":null,"abstract":"<div><h2>Abstract </h2><div><p>The combination of two or more chemotherapy drugs and nanotechnology has emerged as an effective strategy in the fight against cancer. Paclitaxel (PTX) and cisplatin show improved cytotoxic effects on being used together in the chemotherapy of various cancer types, than when used individually. However, these chemotherapy drugs have been shown to have numerous toxic effects in cancer patients. Therefore, the aim of this study was to evaluate the cytotoxicity of PTX and cisplatin associated with gold nanoparticles (AuNps) on HeLa cells containing multiple copies of human papillomavirus 18. AuNps were successfully synthesized with a mean size of 20 to 61 nm, polydispersity index ≥ 0.3, and negative surface charge. Together, PTX and cisplatin associated with AuNps showed a higher cytotoxic effect on HeLa cells than free drugs. The combination of PTX and cisplatin with AuNps potentiated their cytotoxic effects, inducing synergism between the treatments, resulting in HeLa cell death by apoptosis.</p><h3>Graphical abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div></div>","PeriodicalId":55086,"journal":{"name":"Gold Bulletin","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4858264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Organo-gold(III) complexes via mechanochemistry in a ball mill 有机金(III)配合物在球磨机中的机械化学反应

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-01-21 DOI: 10.1007/s13404-021-00302-8

Chao Hu

引用次数: 0

Effect of plasmonic coupling in different assembly of gold nanorods studied by FDTD 用时域有限差分法研究了不同金纳米棒组装过程中等离子体耦合的影响

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-01-16 DOI: 10.1007/s13404-022-00307-x

Aditya K. Sahu, Satyabrata Raj

{"title":"Effect of plasmonic coupling in different assembly of gold nanorods studied by FDTD","authors":"Aditya K. Sahu, Satyabrata Raj","doi":"10.1007/s13404-022-00307-x","DOIUrl":"10.1007/s13404-022-00307-x","url":null,"abstract":"<div><p>The influence of the orientation of gold nanorods in different assemblies has been investigated using the finite difference time domain (FDTD) simulation method. To understand the relative orientation, we vary the size and angle in dimer geometries. Significant effects of plasmon coupling emerged in longitudinal resonances having end-to-end configurations of gold nanorods. The effect of orientational plasmon coupling in dimers gives rise to both bonding and anti-bonding plasmon modes. Effects of various geometries like primary monomer, dimer, trimer, and tetramer structures have been explored and compared with their higher nanorod ensembles. The asymmetric spectral response in a 4 × 4 gold nanorods array indicates a Fano-like resonance. The variation of gap distance in ordered arrays allowed modulation of the Fano resonance mode. The plasmon modes’ resonance wavelength and field enhancement have been tuned by varying the gap distance, angular orientation, size irregularity between the nanorods, and nanorod numbers in an array. The integrated nanostructures studied here are not only significant for fundamental research but also applications in plasmon-based devices.</p></div>","PeriodicalId":55086,"journal":{"name":"Gold Bulletin","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2022-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4648966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The potential of marine-based gold nanomaterials in cancer therapy: a mini-review 海洋基金纳米材料在癌症治疗中的潜力:综述

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-01-14 DOI: 10.1007/s13404-021-00304-6

Neda Baghban, Arezoo Khoradmehr, Iraj Nabipour, Amin Tamadon, Mujib Ullah

{"title":"The potential of marine-based gold nanomaterials in cancer therapy: a mini-review","authors":"Neda Baghban, Arezoo Khoradmehr, Iraj Nabipour, Amin Tamadon, Mujib Ullah","doi":"10.1007/s13404-021-00304-6","DOIUrl":"10.1007/s13404-021-00304-6","url":null,"abstract":"<div><p>Cancer is still one of the most common causes of death today despite advances in its detection and treatment. The present article reviews the application of marine-based gold nanoparticles in the diagnosis and treatment of cancer. The main data were collected from original research articles on the application of different marine-based gold nanoparticles in detecting and imaging cancer cells as well as in drug delivery systems and treatment of cancer. The results show the excellent anticancer potential of both gold nanoparticles and natural marine products. The most studied marine-based gold nanomaterial was chitosan-based ones, in which the role of chitosan is a stabilizer not an anticancer agent. Despite the excellent anticancer potential of different marine natural products, limited studies have been conducted using gold nanoparticles in their composition in cancer therapy. Moreover, most of these studies are related to their application as a drug delivery system not an anticancer drug. Although there are serious challenges in the application of nanoparticles in medicine, marine-based gold nanomaterials may promise an interesting novel strategy in the oncology field.</p></div>","PeriodicalId":55086,"journal":{"name":"Gold Bulletin","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2022-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4573836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Fibers covered with 3D interconnected network of Au nanostructures and their application in SERS detection 三维互连金纳米结构覆盖的纤维及其在SERS检测中的应用

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-01-04 DOI: 10.1007/s13404-021-00303-7

Cuiping Wang, Huan Zhang, Chunrong Wang

引用次数: 1

Gold carbene complexes and beyond: new avenues in gold(I)-carbon coordination chemistry 金碳配合物及其以外:金(I)-碳配位化学的新途径

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2022-01-03 DOI: 10.1007/s13404-021-00298-1

Florian F. Mulks

引用次数: 1

Size-dependent optical and electrochemical properties of gold nanoparticles to L-cysteine 金纳米颗粒对l -半胱氨酸的光学和电化学性质的尺寸依赖性

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-04-28 DOI: 10.1007/s13404-021-00296-3

Pengfei Cao, Nan Wang, Duo Chen, Shengjun Sun, Houyi Ma, Meng Lin

{"title":"Size-dependent optical and electrochemical properties of gold nanoparticles to L-cysteine","authors":"Pengfei Cao, Nan Wang, Duo Chen, Shengjun Sun, Houyi Ma, Meng Lin","doi":"10.1007/s13404-021-00296-3","DOIUrl":"10.1007/s13404-021-00296-3","url":null,"abstract":"<div><p>A series of gold nanoparticles were synthesized by stepwise growth method under the condition of citrate as a reducing agent and stabilizer. The optical properties with the maximum absorption wavelength (λ<sub>max</sub>) and electrochemical properties of the oxidation potential (E<sub><i>p</i></sub>) dependence on the particle size were analyzed. The method of calculating the particle size from the UV-visible spectrum and the electrochemical oxidation peak was deduced, following the theoretical prediction trend and consistent with previous observations. Furthermore, we investigated the application performance based on the electrochemical catalytic activity and the aggregation of the spherical gold nanoparticles using L-cysteine as a target. The results indicated that the optical and electrochemical properties of the gold nanoparticles to L-cysteine were closely related to the particle size of gold nanoparticles. With the increased size of the nanoparticles, the full width at half maximum in the UV-visible absorption spectrum increased and the electrochemical oxidation potential was positively shifted.</p></div>","PeriodicalId":55086,"journal":{"name":"Gold Bulletin","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2021-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13404-021-00296-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5066949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Gold nanorods crosslinking PNIPAM hydrogels via dynamic Au-thiolate interaction with stretchable, adhesive, self-healing, and photothermal properties 金纳米棒通过动态金硫酸酯相互作用交联PNIPAM水凝胶，具有可拉伸、粘接、自愈和光热性能

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2021-01-22 DOI: 10.1007/s13404-021-00293-6

Shijun Lin, Sirui Jiang, Yuchen Zhang, Zhengwei Dai, Yu Dai, Fan Xia, Xiaojin Zhang

{"title":"Gold nanorods crosslinking PNIPAM hydrogels via dynamic Au-thiolate interaction with stretchable, adhesive, self-healing, and photothermal properties","authors":"Shijun Lin, Sirui Jiang, Yuchen Zhang, Zhengwei Dai, Yu Dai, Fan Xia, Xiaojin Zhang","doi":"10.1007/s13404-021-00293-6","DOIUrl":"https://doi.org/10.1007/s13404-021-00293-6","url":null,"abstract":"<p>Gold nanorod (AuNR) nanocomposite hydrogels have attracted increasing attention due to the photothermal effect of AuNRs. However, a facile strategy that avoids multi-step surface modification for synthesis of AuNR crosslinkers is still a critical challenge. Here, AuNRs crosslinking PNIPAM hydrogels were prepared by polymerization of NIPAM with <i>N</i>,<i>N</i>′-bis(acryloyl)cystamine (BACA)-modified AuNRs as crosslinkers. BACA contains a disulfide bond in the structure. Dynamic and reversible Au-thiolate bonding was formed by directly mixing AuNRs and BACA to facilely prepare AuNR crosslinkers before hydrogel formation. The addition of AuNRs gives hydrogels their photothermal effect and remarkable mechanical behaviors. Hydrogels could repeatedly adhere to the surface of pigskin, metal, plastic, and glass with a relatively stable adhesion. The damaged hydrogels heal within 2?min with near-infrared (NIR) laser (808?nm, 300?mW?cm<sup>?2</sup>) irradiation. This work provides a line of thinking for improvement of PNIPAM hydrogels, making them promising for further applications in biomedicine.</p>","PeriodicalId":55086,"journal":{"name":"Gold Bulletin","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13404-021-00293-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4858086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

A causal study on gold, SENSEX, and gold exchange traded funds 黄金、SENSEX和黄金交易所交易基金的因果关系研究

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2020-05-16 DOI: 10.1007/s13404-020-00280-3

Rajit Verma, Dinky Dhiman

引用次数: 2

Agglomerates of Au-Pt bimetallic nanoparticles: synthesis and antibacterial activity 金铂双金属纳米颗粒团聚体的合成及其抗菌活性

IF 2.2 4区工程技术

Gold Bulletin Pub Date : 2020-05-08 DOI: 10.1007/s13404-020-00277-y

R. Britto Hurtado, M. Cortez-Valadez, N. S. Flores-Lopez, M. Flores-Acosta

引用次数: 8