The potential of marine-based gold nanomaterials in cancer therapy: a mini-review

IF 2.2 4区工程技术 Q2 Chemistry

Gold Bulletin Pub Date : 2022-01-14 DOI:10.1007/s13404-021-00304-6

Neda Baghban, Arezoo Khoradmehr, Iraj Nabipour, Amin Tamadon, Mujib Ullah

{"title":"The potential of marine-based gold nanomaterials in cancer therapy: a mini-review","authors":"Neda Baghban, Arezoo Khoradmehr, Iraj Nabipour, Amin Tamadon, Mujib Ullah","doi":"10.1007/s13404-021-00304-6","DOIUrl":null,"url":null,"abstract":"<div><p>Cancer is still one of the most common causes of death today despite advances in its detection and treatment. The present article reviews the application of marine-based gold nanoparticles in the diagnosis and treatment of cancer. The main data were collected from original research articles on the application of different marine-based gold nanoparticles in detecting and imaging cancer cells as well as in drug delivery systems and treatment of cancer. The results show the excellent anticancer potential of both gold nanoparticles and natural marine products. The most studied marine-based gold nanomaterial was chitosan-based ones, in which the role of chitosan is a stabilizer not an anticancer agent. Despite the excellent anticancer potential of different marine natural products, limited studies have been conducted using gold nanoparticles in their composition in cancer therapy. Moreover, most of these studies are related to their application as a drug delivery system not an anticancer drug. Although there are serious challenges in the application of nanoparticles in medicine, marine-based gold nanomaterials may promise an interesting novel strategy in the oncology field.</p></div>","PeriodicalId":55086,"journal":{"name":"Gold Bulletin","volume":"55 1","pages":"53 - 63"},"PeriodicalIF":2.2000,"publicationDate":"2022-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gold Bulletin","FirstCategoryId":"5","ListUrlMain":"https://link.springer.com/article/10.1007/s13404-021-00304-6","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Chemistry","Score":null,"Total":0}

引用次数: 4

Abstract

Cancer is still one of the most common causes of death today despite advances in its detection and treatment. The present article reviews the application of marine-based gold nanoparticles in the diagnosis and treatment of cancer. The main data were collected from original research articles on the application of different marine-based gold nanoparticles in detecting and imaging cancer cells as well as in drug delivery systems and treatment of cancer. The results show the excellent anticancer potential of both gold nanoparticles and natural marine products. The most studied marine-based gold nanomaterial was chitosan-based ones, in which the role of chitosan is a stabilizer not an anticancer agent. Despite the excellent anticancer potential of different marine natural products, limited studies have been conducted using gold nanoparticles in their composition in cancer therapy. Moreover, most of these studies are related to their application as a drug delivery system not an anticancer drug. Although there are serious challenges in the application of nanoparticles in medicine, marine-based gold nanomaterials may promise an interesting novel strategy in the oncology field.

查看原文本刊更多论文

海洋基金纳米材料在癌症治疗中的潜力:综述

尽管癌症的检测和治疗取得了进步，但它仍然是当今最常见的死亡原因之一。本文综述了海洋金纳米颗粒在癌症诊断和治疗中的应用。主要数据收集自不同海洋基金纳米颗粒在检测和成像癌细胞、药物输送系统和癌症治疗中的应用的原始研究文章。结果表明，金纳米颗粒和天然海产品均具有良好的抗癌潜力。研究最多的海洋金纳米材料是壳聚糖基纳米材料，其中壳聚糖的作用是稳定剂而不是抗癌剂。尽管不同的海洋天然产品具有优异的抗癌潜力，但在其组成中使用金纳米颗粒进行癌症治疗的研究有限。此外，这些研究大多与它们作为药物传递系统的应用有关，而不是抗癌药物。虽然纳米颗粒在医学上的应用面临着严峻的挑战，但海洋基金纳米材料可能在肿瘤领域提供一种有趣的新策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Gold Bulletin 工程技术-材料科学：综合

CiteScore

3.30

自引率

4.50%

发文量

审稿时长

3 months

期刊介绍： Gold Bulletin is the premier international peer reviewed journal on the latest science, technology and applications of gold. It includes papers on the latest research advances, state-of-the-art reviews, conference reports, book reviews and highlights of patents and scientific literature. Gold Bulletin does not publish manuscripts covering the snthesis of Gold nanoparticles in the presence of plant extracts or other nature-derived extracts. Gold Bulletin has been published over 40 years as a multidisciplinary journal read by chemists, physicists, engineers, metallurgists, materials scientists, biotechnologists, surface scientists, and nanotechnologists amongst others, both within industry and academia. Gold Bulletin is published in Association with the World Gold Council.