Hno最新文献 - Book学术

[Impact of the coronavirus pandemic on the diagnosis and treatment of head and neck cancer]. [冠状病毒大流行对头颈癌诊断和治疗的影响]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-06 DOI: 10.1007/s00106-024-01520-0

Benjamin Prokein, Michael Dau, Bernhard Frerich

{"title":"[Impact of the coronavirus pandemic on the diagnosis and treatment of head and neck cancer].","authors":"Benjamin Prokein, Michael Dau, Bernhard Frerich","doi":"10.1007/s00106-024-01520-0","DOIUrl":"https://doi.org/10.1007/s00106-024-01520-0","url":null,"abstract":"Background: After the first appearance of COVID-19 cases, the virus spread worldwide within a few months. This led to a decrease in medical consultations. The present study investigates whether this effect had an impact on the diagnosis and treatment of head and neck cancer during the period from 2018 to 2022.Materials and methods: Data from the clinical cancer registration center (KKR) of Mecklenburg-Vorpommern from the 2020-2022 period were compared to those from the two previous years (2018, 2019). Demographic data, case numbers, diagnosis data, International Classification of Diseases (ICD) codes, and TNM classifications were recorded. COVID-19 case numbers were obtained from the Robert Koch Institute (RKI). Data were analyzed using the Mann-Whitney U test and Pearson's correlation.Results: A total of 2332 patient cases could be included in this study. During the lockdown there was neither a significant reduction in tumor diagnoses registered at the KKR nor a correlation between COVID-19 case numbers and tumor diagnoses. Significant differences were found in terms of T category in the year 2022 compared to the pre-COVID years 2018 and 2019. Furthermore, there was a shift in the relative frequencies of some ICD-10 codes.Conclusion: During the COVID-19 pandemic, no significant differences in tumor diagnoses were observed upon comparing the years 2018 to 2022. Contrary to the expectation of a decrease in case numbers during the pandemic due to the lockdown with an increase in tumor stages, a reduction of the T category could be found in 2022, and a shift in the relative frequencies of some ICD-10 codes in the pandemic period was observed.","PeriodicalId":55052,"journal":{"name":"Hno","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Unmet medical needs in otorhinolaryngology]. [耳鼻喉科未满足的医疗需求]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-06 DOI: 10.1007/s00106-024-01529-5

Helmut Schaaf, Georg Kastellis, Gerhard Hesse

{"title":"[Unmet medical needs in otorhinolaryngology].","authors":"Helmut Schaaf, Georg Kastellis, Gerhard Hesse","doi":"10.1007/s00106-024-01529-5","DOIUrl":"https://doi.org/10.1007/s00106-024-01529-5","url":null,"abstract":"Unfulfilled medical wishes and the resulting disappointments often have infrastructural causes and are the result of inadequate services or limited available resources in a medical practice. As annoying as these might be, they can hardly be influenced by the individual therapeutic competence of the ENT physician. The situation is different in the case of unfulfilled medical wishes of patients who cannot be adequately helped for a variety of reasons, whether because of the severity of their illness or because of the particular, predominantly psychosomatic constellations. This can lead to disappointment and unfulfilled expectations on both sides. This article focuses on diseases for which there are no clear organic findings and therefore no clear treatment options, such as surgery or medication, or in which the organic findings are tangible but do not sufficiently explain the underlying condition. In such cases, the treatment measures initiated are not sufficient and do not satisfy the patient. The patient feels misunderstood, which puts additional strain on the relationship between physician and patient. A basic psychosomatic understanding of underlying and subjectively dominant organic complaints-by physicians and patients-is helpful here. In this way, the symptom can also be understood and recognized as a possible expression of psychogenic distress in order to pave way to the necessary initiation of causal therapy. The article is intended to reflect on this and make suggestions for dealing with the topic, using the example of tinnitus suffering in particular.","PeriodicalId":55052,"journal":{"name":"Hno","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Systemic therapy for head and neck cancer-highlights of the 2024 ASCO Annual Meeting]. [头颈癌的系统治疗--2024 年 ASCO 年会亮点]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-05 DOI: 10.1007/s00106-024-01523-x

Markus Blaurock, Cornelia Brunner, Chia-Jung Busch

{"title":"[Systemic therapy for head and neck cancer-highlights of the 2024 ASCO Annual Meeting].","authors":"Markus Blaurock, Cornelia Brunner, Chia-Jung Busch","doi":"10.1007/s00106-024-01523-x","DOIUrl":"https://doi.org/10.1007/s00106-024-01523-x","url":null,"abstract":"Background: Systemic therapy of head and neck squamous cell carcinoma (HNSCC), in contrast to local therapy, is a very general term for the use of drugs that affect the entire organism. Immunotherapy is a subtype of systemic therapy, although the boundaries are hard to define, since the immune system is likely to play an essential role in all treatments. This article focuses on systemic therapy.Materials and methods: All abstracts and presentations on systemic therapy of HNSCC from the American Society of Clinical Oncology (ASCO) 2024 annual congress were assessed for relevance. The main contributions were reviewed and summarized.Results: For the first time, a randomized trial demonstrated a survival advantage for systemic therapy in patients with a poor performance status over best supportive care (BSC). Clinical studies using antibody-drug conjugates (ADCs) show a promising response. In addition, the neoadjuvant approach was resumed through various study approaches.Conclusion: Even in patients with a reduced general condition, systemic therapy can lead to a substantial improvement in overall survival. The systemic therapy approach remains exciting for HNSCC, with new substances and areas of application not only in the palliative situation.","PeriodicalId":55052,"journal":{"name":"Hno","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Chronic crusting of the ear canal with hearing loss]. [耳道慢性结痂伴听力损失]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-04 DOI: 10.1007/s00106-024-01517-9

Achim M Franzen, Annekatrin Coordes

引用次数: 0

[Improved radiological imaging of congenital aural atresia using flat-panel volume CT. German version]. [利用平板容积 CT 改进先天性耳道闭锁的放射成像。德文版]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-01 Epub Date: 2024-09-16 DOI: 10.1007/s00106-024-01511-1

Franz-Tassilo Müller-Graff, Jan von Düring, Johannes Voelker, Fadi Al-Tinawi, Rudolf Hagen, Tilmann Neun, Stephan Hackenberg, Kristen Rak

{"title":"[Improved radiological imaging of congenital aural atresia using flat-panel volume CT. German version].","authors":"Franz-Tassilo Müller-Graff, Jan von Düring, Johannes Voelker, Fadi Al-Tinawi, Rudolf Hagen, Tilmann Neun, Stephan Hackenberg, Kristen Rak","doi":"10.1007/s00106-024-01511-1","DOIUrl":"10.1007/s00106-024-01511-1","url":null,"abstract":"Background: Precise preoperative radiological evaluation of aural atresia is of utmost importance for surgical planning. Until now, multislice computed tomography (MSCT) has been used but it cannot adequately visualize small structures such as the stapes. Flat-panel volume CT (fpVCT) with its secondary reconstructions (fpVCTSECO) offers a high-resolution visualization of the middle ear. New otosurgical planning software also enables detailed 3D reconstruction of the middle ear anatomy.Aim of the work: Evaluation of the use of fpVCTSECO in combination with an otosurgical planning software for a more accurate diagnosis and treatment of congenital aural atresia.Material and methods: Seven patients with congenital aural atresia underwent preoperative MSCT (600 µm slice thickness) and corresponding fpVCT (466 µm slice thickness). In addition, fpVCTSECO (99 µm slice thickness) were reconstructed. The Jahrsdoerfer and Siegert grading scores were determined and their applicability in the abovementioned imaging modalities was evaluated. In addition, the malleus incus complex was analyzed in 3D rendering.Results: Imaging with fpVCTSECO enabled reliable visualization of the abnormalities, in particular the ossicular chain. A significant difference in the Siegert grading score was found. In addition, the malleus-incus complex could be visualized better in 3D.Discussion: The introduction of new imaging techniques and surgical planning techniques into the diagnostic concept of aural atresia facilitates the identification of malformed anatomy and enables systematic analysis. This combination can also help to more accurately classify the pathology and thus increase the safety and success of the surgical procedure.","PeriodicalId":55052,"journal":{"name":"Hno","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11499392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pediatric otorhinolaryngology]. [小儿耳鼻喉科]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-01 Epub Date: 2024-10-23 DOI: 10.1007/s00106-024-01513-z

Stephan Hackenberg

引用次数: 0

[Management of pediatric vascular malformations]. [小儿血管畸形的管理]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-01 Epub Date: 2024-04-02 DOI: 10.1007/s00106-024-01447-6

Veronika Vielsmeier

引用次数: 0

[Particulars of sinogenic orbital complications in children]. [儿童窦源性眼眶并发症的细节]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-01 Epub Date: 2024-02-13 DOI: 10.1007/s00106-024-01421-2

Anja Pähler Vor der Holte, Oliver Bertram, Hans-Jürgen Welkoborsky

{"title":"[Particulars of sinogenic orbital complications in children].","authors":"Anja Pähler Vor der Holte, Oliver Bertram, Hans-Jürgen Welkoborsky","doi":"10.1007/s00106-024-01421-2","DOIUrl":"10.1007/s00106-024-01421-2","url":null,"abstract":"Background: Sinogenic orbital complications in children are relatively rare but critical conditions that require accurate diagnosis and timely appropriate treatment to prevent severe sequelae.Objective: This article concentrates on clinical, diagnostic, and therapeutic specifics of sinogenic orbital complications in children.Materials and methods: The work is based on a literature review (PubMed, Google Scholar) and own experience as well as data from the authors' own pediatric population.Results: In children, sinogenic orbital complications are usually secondary due to acute bacterial sinusitis. Correct distinction between pre- and postseptal cellulitis is of utmost importance for correct diagnostic and therapeutic management in order to prevent long-term sequelae. Preseptal cellulitis can be treated conservatively. If there are signs of postseptal involvement, prompt cross sectional imaging will be required. Depending on the severity of the postseptal involvement, surgical treatment may be necessary.Conclusion: Recent literature debates three main issues: 1) developing models for different combinations of symptoms that reliably distinguish between pre- and postseptal cellulitis; 2) selection of appropriate cross-sectional imaging (MRI vs. CT); and 3) indications for surgery. All three issues will be discussed in detail in this article.","PeriodicalId":55052,"journal":{"name":"Hno","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Rehabilitation with cochlear implants in children with malformations of the inner ear]. [内耳畸形儿童的人工耳蜗康复]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-01 Epub Date: 2024-08-28 DOI: 10.1007/s00106-024-01507-x

Katrin Radeloff, Pascale Sandmann, Claudia Klüner, Andreas Radeloff

引用次数: 0

[Chronic rhinosinusitis in people with cystic fibrosis-an up-to-date review from the perspective of otorhinolaryngology]. [囊性纤维化患者的慢性鼻炎--从耳鼻喉科角度的最新回顾]。

IF 0.8 4区医学

Hno Pub Date : 2024-11-01 Epub Date: 2024-02-16 DOI: 10.1007/s00106-024-01428-9

M Yılmaz Topçuoğlu, O Sommerburg, M O Wielpütz, L Wucherpfennig, S Hackenberg, J G Mainz, I Baumann

{"title":"[Chronic rhinosinusitis in people with cystic fibrosis-an up-to-date review from the perspective of otorhinolaryngology].","authors":"M Yılmaz Topçuoğlu, O Sommerburg, M O Wielpütz, L Wucherpfennig, S Hackenberg, J G Mainz, I Baumann","doi":"10.1007/s00106-024-01428-9","DOIUrl":"10.1007/s00106-024-01428-9","url":null,"abstract":"Background: Cystic fibrosis (CF) is a complex systemic disease involving numerous organ systems. With improved treatment options and increasing life expectancy of persons with CF (PwCF), extrapulmonary manifestations are coming increasingly into the focus. From birth, almost all PwCF have radiologically detectable pathologies in the upper airways attributable to CF-associated chronic rhinosinusitis (CF-CRS).Objective: The aim of this work is to provide an up-to-date overview of CF-CRS from the otorhinolaryngology perspective and to provide the reader with background knowledge and current developments.Pathophysiology: The cystic fibrosis transmembrane conductance regulator (CFTR) gene defect leads to increased viscosity of sinonasal secretions and reduced mucociliary clearance, causing chronic infection and inflammation in the upper airway segment and, consequently, to CF-CRS.Clinical picture and diagnostics: The clinical picture of CF-CRS comprises a wide spectrum from asymptomatic to symptomatic courses. CF-CRS is diagnosed clinically and radiologically.Therapy: Sinonasal saline irrigation is recommended as a conservative treatment measure. Topical corticosteroids are also commonly used. Surgical therapy is reserved for highly symptomatic treatment-refractory patients without a sufficient response to conservative treatment including CFTR modulator (CFTRm) therapies. Depending on the CFTR mutation, CFTRm therapies are the treatment of choice. They not only improve the pulmonary and gastrointestinal manifestations in PwCF, but also have positive effects on CF-CRS.Conclusion: The ENT specialist is part of the interdisciplinary team caring for PwCF. Depending on symptom burden and treatment responsiveness, CF-CRS should be treated conservatively and/or surgically. Modern CFTRm have a positive effect on the clinical course of CF-CRS.","PeriodicalId":55052,"journal":{"name":"Hno","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139742722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0