Journal of Biomechanical Engineering-Transactions of the Asme最新文献

Influence of Left Subclavian Artery Stent Graft Geometry on Blood Hemodynamics in Thoracic Endovascular Aortic Repair.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-17 DOI: 10.1115/1.4067448

Song Xue, Tiandong Lu, Wenqing Hu, Zeyang Xia, Jun Zhang, Xinwu Lu, Jing Xiong

{"title":"Influence of Left Subclavian Artery Stent Graft Geometry on Blood Hemodynamics in Thoracic Endovascular Aortic Repair.","authors":"Song Xue, Tiandong Lu, Wenqing Hu, Zeyang Xia, Jun Zhang, Xinwu Lu, Jing Xiong","doi":"10.1115/1.4067448","DOIUrl":"https://doi.org/10.1115/1.4067448","url":null,"abstract":"Objective: To analyze the hemodynamic changes in different configurations of left subclavian artery (LSA) stent grafts after LSA endovascular reconstruction in thoracic endovascular aortic repair (TEVAR).Methods: For numerical simulation, one 3D thoracic aortic geometry model with an LSA stent graft retrograde curved orientation was reconstructed from post-TEVAR computed tomography angiography images, and four potential LSA graft configurations were modified and reconstructed: three straight (0, 2 and 10 mm aortic extension) and one anterograde configuration. The blood perfusion of the LSA, flow field, hemodynamic wall parameters and vortex evolution process visualized by the Liutex method were analyzed.Results: The average flow in the retrograde configuration decreased by 11.2% compared to that in the basic configuration. When the LSA stent graft extends in the aortic lumen, Flow separation is observed, and vortex structures begin to form at the proximal inferior arterial geometry and the wall of the extension in late systole. A greater extension length and inflow angle upstream resulted in a greater OSI and RRT on the nearby wall of the posterior flow field of the extension.Conclusions: Shorter intra-aortic extension length and smaller LSA stent graft inflow angle may be recommended in TEVAR, considering LSA perfusion and thrombosis risk.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-15"},"PeriodicalIF":1.7,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the influence of morphological features on the vulnerability of lipid-Rich plaques during stenting.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-12 DOI: 10.1115/1.4067398

Jose Colmenarez, Pengfei Dong, Juhwan Lee, David Wilson, Linxia Gu

{"title":"Evaluating the influence of morphological features on the vulnerability of lipid-Rich plaques during stenting.","authors":"Jose Colmenarez, Pengfei Dong, Juhwan Lee, David Wilson, Linxia Gu","doi":"10.1115/1.4067398","DOIUrl":"https://doi.org/10.1115/1.4067398","url":null,"abstract":"Lipid-rich atheromas are linked to plaque rupture in stented atherosclerotic arteries. While fibrous cap thickness is acknowledged as a critical indicator of vulnerability, it is likely that other morphological features also exert influence. However, detailed quantifications of their contributions and intertwined effects in stenting are lacking. Therefore, our goal is to assess the impact of plaque characteristics on the fibrous cap stress and elucidate their underlying mechanisms. We analyzed the stent deployment over a 3D patient-specific coronary artery reconstructed from intravascular optical coherence tomography (IVOCT) through finite element methods. Additionally, we performed sensitivity analysis on 78,000 distinct plaque geometries of two-dimensional arteries for verification. Results from the 3D patient-specific model indicate strong correlations between maximum fibrous cap stress and lipid arc (r=0.769), area stenosis (r=0.550), and lumen curvature (r=0.642). Plaques with lipid arcs > 60°, area stenosis > 75%, and lumen curvatures > 5 mm-1 are at increased rupture risk. While we observed a rise in stress with lipid core thickness, it was less representative than other features. Fibrous cap thickness showed a poor correlation, with the sensitivity analysis revealing its significance only when high stretches are induced by other features, likely due to its J-shaped stress-stretch response. Contrary to physiological pressure, the stent expansion generates unique vulnerable features as the stent load-transferring characteristics modify the plaque?s response. This study is expected to prompt further clinical investigations of other morphological features for predicting plaque rupture in stenting.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-37"},"PeriodicalIF":1.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous-Context, User-Independent, Real-Time Intent Recognition for Powered Lower-Limb Prostheses.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-12 DOI: 10.1115/1.4067401

Krishan Bhakta, Jairo Maldonado-Contreras, Jonathan Camargo, Sixu Zhou, William Compton, Kinsey Herrin, Aaron Young

{"title":"Continuous-Context, User-Independent, Real-Time Intent Recognition for Powered Lower-Limb Prostheses.","authors":"Krishan Bhakta, Jairo Maldonado-Contreras, Jonathan Camargo, Sixu Zhou, William Compton, Kinsey Herrin, Aaron Young","doi":"10.1115/1.4067401","DOIUrl":"https://doi.org/10.1115/1.4067401","url":null,"abstract":"Community ambulation is essential for maintaining a healthy lifestyle, but it poses significant challenges for individuals with limb loss due to complex task demands. In wearable robotics, particularly powered prostheses, there is a critical need to accurately estimate environmental context, such as walking speed and slope, to offer intuitive and seamless assistance during varied ambulation tasks. We developed a user-independent and multi-context, intent recognition system that was deployed in real-time on an open-source knee and ankle powered prosthesis (OSL). We recruited 11 individuals with transfemoral amputation, with 7 participants used for real-time validation. Our findings revealed two main conclusions: 1) the user-independent (IND) performance across speed and slope was not statistically different from user-dependent (DEP) models in real-time, and did not degrade compared to its offline counterparts, 2) IND walking speed estimates showed ~0.09 m/s mean absolute error (MAE) and slope estimates showed ~0.95° MAE across multi-context scenarios. Additionally, we provide an open-source dataset to facilitate further research in accurately estimating speed and slope using an IND approach in real-world walking tasks on a powered prosthesis.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-36"},"PeriodicalIF":1.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does annulus fibrosus lamellar adhesion testing require preconditioning?

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-12 DOI: 10.1115/1.4067399

Sabrina I Sinopoli, Mitchel Whittal, K Josh Briar, Diane E Gregory

{"title":"Does annulus fibrosus lamellar adhesion testing require preconditioning?","authors":"Sabrina I Sinopoli, Mitchel Whittal, K Josh Briar, Diane E Gregory","doi":"10.1115/1.4067399","DOIUrl":"https://doi.org/10.1115/1.4067399","url":null,"abstract":"The interlamellar matrix (ILM), located between the annular layers of the intervertebral disc, is an adhesive component which acts to resist delamination. Investigating the mechanical properties of the ILM can provide us with valuable information regarding risk of disc injury; however given its viscoelastic nature, it may be necessary to conduct preconditioning on tissue samples before measuring these ILM properties. Therefore, the aim of this study was to optimize mechanical testing protocols of the ILM by examining the effect of preconditioning on stiffness and strength of this adhesive matrix. Eighty-eight annular samples were dissected from twenty-two porcine cervical discs and randomized into one of four testing conditions consisting of 10 cycles of 15% strain followed by a 180° adhesive peel test. The four testing groups employed a different strain rate for the 10 cycles of preconditioning: 0.01 mm/s (n=23); 0.1 mm/s (n=26); 1 mm/s (n=23); no preconditioning employed (n=16). Samples preconditioned at 0.01 mm/s were significantly less stiff than those that had not received preconditioning (p=0.014). No other results were found to be statistically significant. Given the lack of differences observed in this study, preconditioning is likely not necessary prior to conducting a 180° peel test. However, if preconditioning is employed, the findings from this study suggest avoiding preconditioning conducted at very slow rates (i.e. 0.01 mm/s) as the long testing time may negatively affect the tissue.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-11"},"PeriodicalIF":1.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparing patellofemoral kinematics assessed with a novel Muscle Actuator System and an Oxford Rig using non-cadaveric knees.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-12 DOI: 10.1115/1.4067400

Alexandre Galley, Samira Vakili, Ilya Borukhov, Brent Lanting, Stephen J Piazza, Ryan Willing

{"title":"Comparing patellofemoral kinematics assessed with a novel Muscle Actuator System and an Oxford Rig using non-cadaveric knees.","authors":"Alexandre Galley, Samira Vakili, Ilya Borukhov, Brent Lanting, Stephen J Piazza, Ryan Willing","doi":"10.1115/1.4067400","DOIUrl":"https://doi.org/10.1115/1.4067400","url":null,"abstract":"Total knee replacement (TKR) failure, low patient satisfaction and high revision surgery rates may stem from insufficient pre-clinical testing. Conventional joint motion simulators for pre-clinical testing of TKR implants manipulate a knee joint in force, displacement, or simulated muscle control. However, a rig capable of using all three control modes has yet to be described in literature. This study aimed to validate a novel platform, the muscle actuator system (MAS), that can generate gravity-dependent, quadriceps-controlled squatting motions representative of an Oxford rig knee simulator and is mounted onto a force/displacement-control-capable joint motion simulator. Synthetic knee joint phantoms were created that comprised revision TKR implants and key extensor and flexor mechanism analogues, but no ligaments. The combined system implemented a constant force vector acting from simulated hip-to-ankle coordinates, effectively replicating gravity as observed in an Oxford rig. Quadriceps forces and patellofemoral joint kinematics were measured to assess the performance of the MAS and these tests showed high levels of repeatability and reproducibility. Forces and kinematics measured at a nominal patellar tendon length, and with patella alta and baja, were compared against those measured under the same conditions using a conventional Oxford rig, the Pennsylvania State Knee Simulator (PSKS). There was disagreement in absolute kinematics and muscle forces, but similar trends resulting from changing prosthesis design or patellar tendon length.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-31"},"PeriodicalIF":1.7,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simulation Study of the Upper-limb Isometric Wrench Feasible Set with Glenohumeral Joint Constraints.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-05 DOI: 10.1115/1.4067329

Nasser Rezzoug, Antun Skuric, Vincent Padois, David Daney

{"title":"Simulation Study of the Upper-limb Isometric Wrench Feasible Set with Glenohumeral Joint Constraints.","authors":"Nasser Rezzoug, Antun Skuric, Vincent Padois, David Daney","doi":"10.1115/1.4067329","DOIUrl":"https://doi.org/10.1115/1.4067329","url":null,"abstract":"The aim of this work is to improve musculoskeletal-based models of the upper-limb Wrench Feasible Set i.e. the set of achievable maximal wrenches at the hand for applications in collaborative robotics and computer aided ergonomics. In particular, a recent method performing wrench capacity evaluation called the Iterative Convex Hull Method is upgraded in order to integrate non dislocation and compression limitation constraints at the glenohumeral joint not taken into account in the available models. Their effects on the amplitude of the force capacities at the hand, glenohumeral joint reaction forces and upper-limb muscles coordination in comparison to the original iterative convex hull method are investigated in silico. The results highlight the glenohumeral potential dislocation for the majority of elements of the wrench feasible set with the original Iterative Convex Hull method and the fact that the modifications satisfy correctly stability constraints at the glenohumeral joint. Also, the induced muscles coordination pattern favors the action of stabilizing muscles, in particular the rotator-cuff muscles, and lowers that of known potential destabilizing ones according to the literature.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-32"},"PeriodicalIF":1.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Influence of Occupant Characteristics, Seat Positioning, and Pre-Crash Maneuvers on Front Passenger Safety Performance.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-05 DOI: 10.1115/1.4067331

Akshay Dahiya, Costin Untaroiu

{"title":"The Influence of Occupant Characteristics, Seat Positioning, and Pre-Crash Maneuvers on Front Passenger Safety Performance.","authors":"Akshay Dahiya, Costin Untaroiu","doi":"10.1115/1.4067331","DOIUrl":"https://doi.org/10.1115/1.4067331","url":null,"abstract":"Crash avoidance vehicle maneuvers are known to influence occupant posture and kinematics which consequently may influence injury risks in the event of a crash. In this work, a generic buck vehicle finite element (FE) model was developed which included the vehicle interior and the front passenger airbag (PAB). Seat position and occupant characteristics including anthropometry, sex, and age were varied in a design of experiments. Two pre-crash maneuvers representing 1) a generic 1g braking and 2) turning-and-braking scenarios were simulated. Rigid-body human models with active joints (GHBMCsi-pre models) obtained by morphing a 50th male model to selected anthropometries were used in pre-crash simulations. The kinematics data of belted GHBMCsi-pre models at the end of the pre-crash phase were transferred using a developed switch algorithm to the corresponding morphed GHBMC occupant simplified (OS) models to predict occupant injury risks. During both pre-crash maneuvers, the occupant's head and thorax moved forward towards the dashboard. Therefore, the head and thorax contacted the PAB earlier, leading to lower head accelerations when the pre-crash phase was considered. Overall, it was concluded that pre-crash braking decreased the severity of injury sustained by the passenger. Seat track position and seat recline angle showed the highest influence on the head injury criteria (HIC). The brain injury criteria (BrIC), and neck injury criteria (Nij) were most sensitive to pre-crash maneuver type, seat recline angle, and occupant size.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-29"},"PeriodicalIF":1.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational analysis of flow and transport suggests reduced oxygen levels within intracranial aneurysms, especially in individuals with sickle-cell disease.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-05 DOI: 10.1115/1.4067323

Marisa Bazzi, Hadi Wiputra, David Wood, Victor H Barocas

{"title":"Computational analysis of flow and transport suggests reduced oxygen levels within intracranial aneurysms, especially in individuals with sickle-cell disease.","authors":"Marisa Bazzi, Hadi Wiputra, David Wood, Victor H Barocas","doi":"10.1115/1.4067323","DOIUrl":"https://doi.org/10.1115/1.4067323","url":null,"abstract":"Sickle cell disease (SCD) is a genetic condition characterized by an abundance of sickle hemoglobin in red blood cells. SCD patients are more prone to intracranial aneurysms (ICA) compared to the general population, with distinctive features such as multiple intracranial aneurysms: 66% of SCD patients with ICAs have multiples ICAs, compared to 20% in non-sickle patients. The exact mechanism behind these associations is not fully understood, but there is a hypothesized link between hypoxia and impaired synthesis of extracellular matrix, which may weaken the vessel walls, favoring aneurysm formation and rupture. SCD patients experience reduced blood oxygen levels, potentially exacerbating hypoxia in ICAs, and potentially contributing to aneurysm development and early onset in these patients. In this work, we performed a series of computational studies (Fluent) using idealized geometries to investigate the key differences in the oxygen transport and blood flow dynamics inside an aneurysm formation for sickle and non-sickle cases. We found that using SCD parameters resulted in a 14% to 68% reduction in blood flow and a 37% to 70% reduction in oxygen availability within the aneurysm, depending on the vessel curvature and the aneurysm throat diameter, due to factors including oxygen-dependent viscosity and alteration in the oxygen transport. The results indicate that depending on geometry and flow characteristics, some degree of hypoxia maybe present in aneurysm bulb and would be more severe in SCD patients. This study hopes to bring into attention the potential presence of hypoxic environment in the aneurysm bulb.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-26"},"PeriodicalIF":1.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of internal disc strain under dynamic loading via high-frequency ultrasound.

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-05 DOI: 10.1115/1.4067330

Elnaz Ghajar-Rahimi, Diya D Sakhrani, Radhika Kulkarni, Shiyin Lim, Blythe B Dumerer, Annie Labine, Michael E Abbott, Grace O'Connell, Craig Goergen

{"title":"Quantification of internal disc strain under dynamic loading via high-frequency ultrasound.","authors":"Elnaz Ghajar-Rahimi, Diya D Sakhrani, Radhika Kulkarni, Shiyin Lim, Blythe B Dumerer, Annie Labine, Michael E Abbott, Grace O'Connell, Craig Goergen","doi":"10.1115/1.4067330","DOIUrl":"https://doi.org/10.1115/1.4067330","url":null,"abstract":"Measurement of internal intervertebral disc strain is paramount for understanding the underlying mechanisms of injury and validating computational models. Although advancements in noninvasive imaging and image processing have made it possible to quantify strain, they often rely on visual markers that alter tissue mechanics and are limited to static testing that is not reflective of physiologic loading conditions. The purpose of this study was to integrate high-frequency ultrasound and texture correlation to quantify disc strain during dynamic loading. We acquired ultrasound images of the posterior side of bovine discs in the8 transverse plane throughout 0-0.5mm of assigned axial compression at 0.3-0.5Hz. Internal Green-Lagrangian strains were quantified across time using direct deformation estimation, a texture correlation method. Median principal strain at maximal compression 0.038 ± 0.011 for E1 and -0.042 ± 0.012 for E2. Strain distributions were heterogeneous through the discs, with higher strains noted near the disc endplates. This methodological report shows that high-frequency ultrasound can be a valuable tool for quantification of disc strain under dynamic loading conditions. Further work will be needed to determine if diseased or damaged discs reveal similar strain patterns, opening the possibility of clinical use in patients with disc disease.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

We Will, We Will Shock You: Adaptive Versus Conventional Functional Electrical Stimulation in Individuals Post-Stroke. 我们会，我们会让你震惊：中风后患者的自适应功能性电刺激与传统功能性电刺激。

IF 1.7 4区医学

Journal of Biomechanical Engineering-Transactions of the Asme Pub Date : 2024-12-01 DOI: 10.1115/1.4066419

Margo C Donlin, Jill S Higginson

{"title":"We Will, We Will Shock You: Adaptive Versus Conventional Functional Electrical Stimulation in Individuals Post-Stroke.","authors":"Margo C Donlin, Jill S Higginson","doi":"10.1115/1.4066419","DOIUrl":"10.1115/1.4066419","url":null,"abstract":"Functional electrical stimulation (FES) is often used in poststroke gait rehabilitation to address decreased walking speed, foot drop, and decreased forward propulsion. However, not all individuals experience clinically meaningful improvements in gait function with stimulation. Previous research has developed adaptive functional electrical stimulation (AFES) systems that adjust stimulation timing and amplitude at every stride to deliver optimal stimulation. The purpose of this work was to determine the effects of a novel AFES system on functional gait outcomes and compare them to the effects of the existing FES system. Twenty-four individuals with chronic poststroke hemiparesis completed 64-min walking trials on an adaptive and fixed-speed treadmill with no stimulation, stimulation from the existing FES system, and stimulation from the AFES system. There was no significant effect of stimulation condition on walking speed, peak dorsiflexion angle, or peak propulsive force. Walking speed was significantly faster and peak propulsive force was significantly larger on the adaptive treadmill (ATM) than the fixed-speed treadmill (both p < 0.0001). Dorsiflexor stimulation timing was similar between stimulation conditions, but plantarflexor stimulation timing was significantly improved with the AFES system compared to the FES system (p = 0.0059). Variability between and within subjects was substantial, and some subjects experienced clinically meaningful improvements in walking speed, peak dorsiflexion angle, and peak propulsive force. However, not all subjects experienced benefits, suggesting that further research to characterize which subjects exhibit the best instantaneous response to FES is needed to optimize poststroke gait rehabilitation using FES.","PeriodicalId":54871,"journal":{"name":"Journal of Biomechanical Engineering-Transactions of the Asme","volume":" ","pages":""},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11500808/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0