Felix Kunz, Angelika Stellzig-Eisenhauer, Lisa Marie Widmaier, Florian Zeman, Julian Boldt
{"title":"Assessment of the quality of different commercial providers using artificial intelligence for automated cephalometric analysis compared to human orthodontic experts.","authors":"Felix Kunz, Angelika Stellzig-Eisenhauer, Lisa Marie Widmaier, Florian Zeman, Julian Boldt","doi":"10.1007/s00056-023-00491-1","DOIUrl":"10.1007/s00056-023-00491-1","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this investigation was to evaluate the accuracy of various skeletal and dental cephalometric parameters as produced by different commercial providers that make use of artificial intelligence (AI)-assisted automated cephalometric analysis and to compare their quality to a gold standard established by orthodontic experts.</p><p><strong>Methods: </strong>Twelve experienced orthodontic examiners pinpointed 15 radiographic landmarks on a total of 50 cephalometric X‑rays. The landmarks were used to generate 9 parameters for orthodontic treatment planning. The \"humans' gold standard\" was defined by calculating the median value of all 12 human assessments for each parameter, which in turn served as reference values for comparisons with results given by four different commercial providers of automated cephalometric analyses (DentaliQ.ortho [CellmatiQ GmbH, Hamburg, Germany], WebCeph [AssembleCircle Corp, Seongnam-si, Korea], AudaxCeph [Audax d.o.o., Ljubljana, Slovenia], CephX [Orca Dental AI, Herzliya, Israel]). Repeated measures analysis of variances (ANOVAs) were calculated and Bland-Altman plots were generated for comparisons.</p><p><strong>Results: </strong>The results of the repeated measures ANOVAs indicated significant differences between the commercial providers' predictions and the humans' gold standard for all nine investigated parameters. However, the pairwise comparisons also demonstrate that there were major differences among the four commercial providers. While there were no significant mean differences between the values of DentaliQ.ortho and the humans' gold standard, the predictions of AudaxCeph showed significant deviations in seven out of nine parameters. Also, the Bland-Altman plots demonstrate that a reduced precision of AI predictions must be expected especially for values attributed to the inclination of the incisors.</p><p><strong>Conclusion: </strong>Fully automated cephalometric analyses are promising in terms of timesaving and avoidance of individual human errors. At present, however, they should only be used under supervision of experienced clinicians.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"145-160"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10112741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharina Flanze, Sandra Riemekasten, Christian Hirsch, Till Koehne
{"title":"Perception of facial and dental asymmetries and their impact on oral health-related quality of life in children and adolescents.","authors":"Katharina Flanze, Sandra Riemekasten, Christian Hirsch, Till Koehne","doi":"10.1007/s00056-023-00490-2","DOIUrl":"10.1007/s00056-023-00490-2","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the perception of facial and dental asymmetries in children and adolescents and how these asymmetries affect their psychosocial and emotional well-being.</p><p><strong>Methods: </strong>The study included 66 children and adolescents (7-15 years) with a deviation between the maxillary and mandibular dental midlines of > 0.5 mm. The soft tissues of the face were scanned using stereophotogrammetry. Psychosocial and emotional impairments were assessed using the German version of the Child Perceptions Questionnaire (CPQ-G8-10 and 11-14).</p><p><strong>Results: </strong>The mean midline deviation of the study group was 2.3 mm with no significant gender differences. Girls perceived facial asymmetry significantly more often than boys (p < 0.01). However, stereophotogrammetry showed no significant differences in facial morphology between subjects who perceived their face as asymmetrical and those who perceived it as symmetrical. Interestingly, we observed a significant correlation between the deviation of the dental midline and the lateral displacement of gonion (p < 0.05) and cheilion (p < 0.01). Psychosocial and emotional impairment was significantly higher in girls than in boys (p < 0.05). However, there was no significant correlation with the measured facial asymmetries. In contrast, the CPQ subscale score was 2.68 points higher in individuals with a dental midline shift ≥ 3 mm (p < 0.01), independent of age and gender.</p><p><strong>Conclusion: </strong>Although girls perceived facial asymmetries more strongly than boys do, this perception could not be objectified by extraoral measurements. A midline shift of 3 mm or more had a negative impact on the oral health-related quality of life of affected children and adolescents.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"137-144"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10113706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mitteilungen der DGKFO.","authors":"Sema Safi","doi":"10.1007/s00056-025-00586-x","DOIUrl":"https://doi.org/10.1007/s00056-025-00586-x","url":null,"abstract":"","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":"86 3","pages":"194-195"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Lips, Erika Calvano Küchler, Isabela Ribeiro Madalena, Patricia Nivoloni Tannure, Leonardo Santos Antunes, Livia Azeredo Alves Antunes, Marcelo Castro Costa, Peter Proff, Christian Kirschneck, Flares Baratto-Filho
{"title":"Non-syndromic supernumerary teeth and association with a self-reported family history of cancer.","authors":"Andrea Lips, Erika Calvano Küchler, Isabela Ribeiro Madalena, Patricia Nivoloni Tannure, Leonardo Santos Antunes, Livia Azeredo Alves Antunes, Marcelo Castro Costa, Peter Proff, Christian Kirschneck, Flares Baratto-Filho","doi":"10.1007/s00056-023-00504-z","DOIUrl":"10.1007/s00056-023-00504-z","url":null,"abstract":"<p><strong>Background: </strong>Supernumerary teeth are an alteration of dental developmental and result in the formation of teeth above the usual number. Epidemiologic studies suggested that patients with dentofacial anomalies and their family members may present an increased risk of developing cancer, including female breast cancer and gynecologic cancers. These observations indicate that genetic alterations that result in dental anomalies may be related to cancer development. Thus, the aim of the present study was to evaluate the association between supernumerary teeth and a family history of female breast cancer and gynecologic cancers.</p><p><strong>Methods: </strong>The diagnosis of supernumerary teeth was based on clinical and radiographic examinations. For data collection, a questionnaire asking for information regarding ethnicity, age, gender, and self-reported family history of cancer up to the second generation was used. Statistical analysis was performed using the Χ<sup>2</sup> test and Fisher's exact test with an established α of 5%.</p><p><strong>Results: </strong>A total of 344 patients were included; 47 of them had one or more non-syndromic supernumerary teeth (not associated with any syndrome or cleft lip and palate) and 297 were control patients. Age, ethnicity, and gender distribution were not statistically different between the group with supernumerary teeth and the control group (p > 0.05). The supernumerary teeth were most commonly observed in the incisors area. Breast cancer (n = 17) was the most commonly self-reported type of cancer, followed by uterine cervical (n = 10), endometrial (n = 2), and ovarian (n = 1) cancers. Endometrial cancer was significantly associated with the diagnosis of supernumerary teeth (p = 0.017).</p><p><strong>Conclusion: </strong>This study suggests that patients with supernumerary teeth possess a higher risk of having family members with endometrial cancer.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"131-136"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138489127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Babak Sayahpour, Diana Lau, Sara Eslami, Sarah Buehling, Stefan Kopp, Abdolreza Jamilian, Sachin Chhatwani
{"title":"Posttreatment stability following therapy using passive self-ligating brackets: extraction vs. nonextraction.","authors":"Babak Sayahpour, Diana Lau, Sara Eslami, Sarah Buehling, Stefan Kopp, Abdolreza Jamilian, Sachin Chhatwani","doi":"10.1007/s00056-023-00501-2","DOIUrl":"10.1007/s00056-023-00501-2","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effects of lower premolar extraction on posttreatment stability one year following fixed orthodontic treatment with passive self-ligating brackets (Damon system, Ormco, Orange, CA, USA).</p><p><strong>Methods: </strong>All patients were treated with fixed orthodontic appliances using passive self-ligating brackets (Damon). For retention, removable Hawley retainers were used. Two groups of patients were included in the study. Each group consisted of 23 patients: group Ex consisted of 10 male and 13 female patients (13.4 ± 1.6 years old) with extraction of lower first premolars and group NonEx consisted of 11 male and 12 female patients (13.4 ± 3.9 years old) without dental extractions. The patients' dental models and photographs were assessed at T0 (pretreatment), T1 (the end of active orthodontic treatment: 3.3 ± 1.0 years in the Ex and 2.3 ± 0.8 years in the NonEx group) and at T2 (1 year posttreatment). All lower casts were scanned and the following dental parameters were recorded and compared between the two groups: intercanine width (ICW), anterior arch width (AAW), intermolar width (IMW), Little's irregularity index (LII) and gingival recessions.</p><p><strong>Results: </strong>An increase in ICW (group Ex: 1.20 ± 2.51 mm and group NonEx: 0.84 ± 1.48 mm) by the end of active treatment (T1; P < 0.05), as well as a relapse regarding the ICW (group Ex: -0.1 ± 0.47 mm and group NonEx: -67% ± 0.38 mm) one year post-treatment (T2) were recorded in the samples. Relapse in the non-extraction group was statistically and clinically significant, whereas ICW values remained relatively stable in the extraction group during the posttreatment period (T1-T2). The irregularity index decreased during treatment (group Ex: -8.79 ± 6.36 mm and group NonEx: -5.24 ± 2.99 mm) and relapsed in both groups (group Ex: 0.57 ± 90 mm and group NonEx: 0.27 ± 0.53). The rate of relapse in LII was correlated to the relapse rate of ICW. A reduction of IMW was recorded in the Ex group (-1.89 ± 1.82 mm) during active treatment (P < 0.05), which remained stable 1 year posttreatment. AAW increased in both groups (group Ex: 2.77 ± 1.77 mm and group NonEx: 1.77 ± 2.04 mm) throughout active treatment and remained stable at T2.</p><p><strong>Conclusion: </strong>Intergroup comparison revealed that ICW remained stable 1 year posttreatment in the Ex group, whereas high relapse of ICW was recorded in the NonEx group. Furthermore, risk of a relapse of LII appears to be higher in cases with a relapse of the ICW.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"1-9"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41241006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kathrin Duske, Billan Turan, Cornelia Prinz, Jan Hendrik Lenz, Franka Stahl, Mareike Warkentin
{"title":"Functionality testing of an innovative biomechanically optimized and surface-modified orthodontic mini-screw-a comparative study.","authors":"Kathrin Duske, Billan Turan, Cornelia Prinz, Jan Hendrik Lenz, Franka Stahl, Mareike Warkentin","doi":"10.1007/s00056-023-00508-9","DOIUrl":"10.1007/s00056-023-00508-9","url":null,"abstract":"<p><strong>Purpose: </strong>The failure rate of orthodontic mini-screws depends strongly on primary stability and, thus, on insertion torque. Further improvement regarding the failure rate might be achieved by modifying the surface coating. Therefore, the aim of the study was to investigate the stability of a newly designed and surface-modified orthodontic mini-screw in beagle dogs.</p><p><strong>Methods: </strong>Newly designed mini-screws coated either with DOTIZE® or DOTIZE®-copper (DOT GmbH, Rostock, Germany; each: n = 24) were inserted in the mandibles of eight beagle dogs for a duration of 8 months. Insertion and removal torque were measured. These data were compared to values generated by using the artificial bone material Sawbones® (Sawbones Europe AB, Malmö, Sweden). Experiments with and without torque limitation (each: n = 5) were run. The bone-to-implant contact rate and the amount of bone between the threads were examined. Statistical significance was set at P < 0.05.</p><p><strong>Results: </strong>The success rates of the in vivo study reached high levels with 95.3% for the DOTIZE-coated and 90.5% for the DOTIZE-copper-coated screws, whereas the insertion and removal torque did not differ between the coatings. During insertion, a torque limitation of 20 Ncm was necessary to ensure that the recommended limit was not exceeded. The insertion in Sawbones without torque limitation revealed a significantly higher torque compared to torque-limited insertion (18.2 ± 1.3 Ncm, 23.6 ± 1.3 Ncm). Bending occurred (n = 5) in the thread-free part of the mini-screw.</p><p><strong>Conclusions: </strong>Surface coating might be able to improve the performance of orthodontic mini-screws. The study showed high success rates and stable mini-screws until the end of observation. Further investigations are necessary.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"170-181"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Polylactic acid 3D printing settings and precision in dentistry.","authors":"Amnuay Kleebayoon, Viroj Wiwanitkit","doi":"10.1007/s00056-025-00581-2","DOIUrl":"https://doi.org/10.1007/s00056-025-00581-2","url":null,"abstract":"","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coefficient of efficiency and effectiveness of functional appliances in class II malocclusion treatment : A systematic review.","authors":"Keerthi Venkatesan, Vignesh Kailasam, Sridevi Padmanabhan, Nikhillesh Vaiid","doi":"10.1007/s00056-025-00585-y","DOIUrl":"https://doi.org/10.1007/s00056-025-00585-y","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the coefficient of efficiency and effectiveness of removable and fixed functional appliances in class II malocclusion treatment.</p><p><strong>Data sources: </strong>Search of studies in five databases (Medline via PubMed, Cochrane library, LILACS, SCOPUS, and SciELO) that measured mandibular skeletal changes following functional therapy was conducted until 15 April 2024.</p><p><strong>Study selection: </strong>All study designs including randomized and controlled clinical trials (RCT), prospective and retrospective studies were included. Data were extracted independently by two authors from studies that fulfilled the inclusion criteria. Mandibular length changes of class II patients treated with functional appliances were collated for each retrieved study.</p><p><strong>Results: </strong>From 6796 potentially eligible studies, 90 were considered for this systematic review. Four were RCTs which were graded with the Cochrane risk of bias tool. Three were assessed as having low and one as having moderate risk of bias. The other 86 studies were graded with the modified Downs and Black tool which revealed that 47 showed low, 38 low/moderate, and 1 a moderate risk of bias. The most commonly assessed appliances were the Twin Block which was used on 783 patients, the Frankel appliance on 573, the Herbst appliance on 530, the Activator on 449, the Forsus appliance on 394, the MARA appliance on 202, and the Bionator on 133, for a total of 3064 treated patients.</p><p><strong>Conclusion: </strong>This systematic review provides conclusive evidence that the Twin Block appliance demonstrated the highest coefficient of efficiency among all the evaluated appliances (0.46 mm/month), while the Forsus fatigue resistant device (FFRD) had the highest coefficient of efficiency among the fixed functional appliances (0.41 mm/month).</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Kunz, N F Nordblom, B Goetz, L Fenger, A Stellzig-Eisenhauer
{"title":"Which of the nine facial profiles according to AM Schwarz is the most (un)attractive?","authors":"F Kunz, N F Nordblom, B Goetz, L Fenger, A Stellzig-Eisenhauer","doi":"10.1007/s00056-025-00584-z","DOIUrl":"https://doi.org/10.1007/s00056-025-00584-z","url":null,"abstract":"<p><strong>Objective: </strong>The human profile has always been fascinating to artists, scientists, and physicians. In the mid 20th century, AM Schwarz created a profile analysis for orthodontics, which categorizes both the sagittal position of the midface as well as the position of the chin, and is still widely used today. In combination, this analysis leads to nine different profile types, which are assumed to differ in terms of their attractiveness. Since there has been hardly any scientific research in this area so far, the aim of this study was to quantify the attractiveness of the nine profile types according to AM Schwarz.</p><p><strong>Methods: </strong>The \"Basel face model\" is a three-dimensional (3D) facial dataset that was created artificially by morphing a total of 100 female and 100 male 3D face scans. For the present study, this face model was modified to ideally represent all nine profile types according to AM Schwarz. The representation of those nine facial models depicted in a standardized lateral perspective were assessed in terms of attractiveness by 1261 volunteers of different ages and educational level. The ratings were statistically analyzed using repeated measures analysis of variance (ANOVA) and pairwise comparisons.</p><p><strong>Results: </strong>The results revealed significant differences in attractiveness regarding the nine profile types. Average faces were perceived significantly more attractive than antefaces and these in turn were perceived more attractive than retrofaces. Furthermore, straight and backward-slanting profiles were rated significantly more attractive than forward-slanting profiles. There were no clinically relevant differences between the assessments of males and females or between raters of different educational levels.</p><p><strong>Conclusion: </strong>The perceived attractiveness of the nine profile types according to AM Schwarz differed significantly. This perception did not seem to be affected by gender or the level of education.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143812924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Serafin, B Baldini, O Rossi, G Perrotti, A Caprioglio
{"title":"Novel approach to three-dimensional intermaxillary skeletal assessment : Correlation between the ANB angle and the bisector Wits appraisal.","authors":"M Serafin, B Baldini, O Rossi, G Perrotti, A Caprioglio","doi":"10.1007/s00056-025-00583-0","DOIUrl":"https://doi.org/10.1007/s00056-025-00583-0","url":null,"abstract":"<p><strong>Purpose: </strong>The present study aimed to compare and correlate the ANB angle with the bisector Wits appraisal for a three-dimensional (3D) assessment of the maxillomandibular sagittal relationship using a cone beam computed tomography (CBCT) dataset.</p><p><strong>Methods: </strong>After outlier removal, 351 CBCT scans were chosen based on inclusion criteria (high quality, full-cranium field of view [FOV], slice thickness 150-300 μm) and analyzed using 3DSlicer software (Brigham and Women's Hospital, Boston, MA, USA, version 5.2.2). Eight anatomical landmarks were manually annotated, identified on axial views, and confirmed on the rendered volume image. The coordinates of each landmark were exported and the ANB (°) and bisector-Wits (mm) measurements were constructed. Dahlberg's D tested the intraobserver reliability and two-sample Kolmogorov-Smirnov test was executed to assess normality and to select the subsequent tests. Spearman's rank correlation coefficient (ρ) was utilized to correlate the angular (ANB) and linear (bisector-Wits) measurements, whereas the Siegel estimator for nonparametric linear regression was employed to establish norm values by the correlation equation. Significance was set at p < 0.05 with correlation coefficients exceeding ρ > 0.70 deemed clinically relevant.</p><p><strong>Results: </strong>High (ρ = 0.773) and statistically significant (p < 0.001) correlations between the ANB and bisector-Wits measurements were found. The obtained equation was the following: bisector-Wits = 1.06 × ANB - 6.32. Therefore, the obtained rounded norm range for bisector-Wits for skeletal class I sagittal relationship was determined to be from -6.3 to -2.1 mm (-4.2 ± 2.1 mm). Values less than -6.3 mm correspond to a class III, whereas greater than -2.1 mm correspond to a class II skeletal relationship.</p><p><strong>Conclusion: </strong>The study revealed a statistically significant correlation between the ANB and bisector-Wits. From a 3D perspective, the bisector-Wits represents a reliable parameter to assess maxilla-mandibular skeletal discrepancies instead of the ANB angle, also adhering to radioprotection principles by limiting the FOV to the maxillary complex only and potentially reducing the radiation exposure in CBCT-based cephalometry.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}