Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie最新文献

{"title":"Advancing oral immunology for improving oral health.","authors":"James Deschner, Agnes Schröder, Manuel Weber, Kerstin Galler, Peter Proff, Christian Kirschneck, Aline Bozec, Jonathan Jantsch","doi":"10.1007/s00056-023-00473-3","DOIUrl":"10.1007/s00056-023-00473-3","url":null,"abstract":"<p><p>Although substantial progress has been made in dentistry in terms of diagnosis and therapy, current treatment methods in periodontology, orthodontics, endodontics, and oral and maxillofacial surgery, nevertheless, suffer from numerous limitations, some of which are associated with a dramatic reduction in the quality of life. Many general mechanisms of inflammation and immunity also apply to the oral cavity and oral diseases. Nonetheless, there are special features here that are attributable, on the one hand, to developmental biology and, on the other hand, to the specific anatomical situation, which is characterized by a close spatial relationship of soft and hard tissues, exposure to oral microbiota, and to a rapid changing external environment. Currently, a comprehensive and overarching understanding is lacking about how the immune system functions in oral tissues (oral immunology) and how oral immune responses contribute to oral health and disease. Since advances in translational immunology have created a game-changing shift in therapy in rheumatology, allergic diseases, inflammatory bowel disease, and oncology in recent years, it is reasonable to assume that a better understanding of oral immunology might lead to practice-changing diagnostic procedures and therapies in dentistry and thereby also profoundly improve oral health in general.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"33-37"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11747000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9982988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can surgically assisted rapid palatal expansion (SARPE) be recommended over orthodontic rapid palatal expansion (ORPE) for girls above the age of 14? : A cone-beam CT study on midpalatal suture maturation.","authors":"Dries Govaerts, Oliver Da Costa, Melisa Garip, François Combes, Reinhilde Jacobs, Constantinus Politis","doi":"10.1007/s00056-023-00487-x","DOIUrl":"10.1007/s00056-023-00487-x","url":null,"abstract":"<p><strong>Background: </strong>For patients with a maxillary transversal deficiency (MTD), various treatment options are available, partly based on the practitioner's experience. This study aimed to determine a cut-off age for decision making between surgically assisted rapid palatal expansion (SARPE) over orthodontic rapid palatal expansion (ORPE) based on skeletal maturation in a female population.</p><p><strong>Methods: </strong>A total of 100 cone beam computed tomography (CBCT) images of young females were analyzed on maturation of the pterygomaxillary (PMS), zygomaticomaxillary (ZMS), transpalatal (TPS), and midpalatal (MPS) sutures. Based on the maturation of these four junctions, four independent observers had to determine whether they would prefer ORPE or SARPE to widen the maxilla.</p><p><strong>Results: </strong>For the PMS, the results show a closure of 83-100% from 13 to 17 years. As for the TPS, a closure of 78-85% was observed from 15 years of age. For the 15- to 17-year-old females, a closed ZMS was present in 32-47%. Regarding MPS, closed sutures presented in 61% (stages D and E) of the 15-year-old females. The cut-off age at which SARPE was recommended was 15.1 years for the orthodontist observers and 14.8 years for the maxillofacial surgeon observers.</p><p><strong>Conclusions: </strong>Significant maturation of MPS was reached at the age of 15 in a female population. The PMS, TPS, MPS, and ZMS closed sequentially. A comprehensive diagnostic approach is necessary for choosing the appropriate treatment. When in doubt, age could assist decision making in a female population, with a cut-off age of 15 years in favor of SARPE based on this study.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"38-48"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11746970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9758384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitteilungen der DGKFO.","authors":"","doi":"10.1007/s00056-024-00572-9","DOIUrl":"10.1007/s00056-024-00572-9","url":null,"abstract":"","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"58-66"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupressure versus NSAID for relief of orthodontic pain : A randomized controlled clinical trial.","authors":"Moataz Elshehaby, Marwa Ali Tawfik, Mona A Montasser","doi":"10.1007/s00056-023-00476-0","DOIUrl":"10.1007/s00056-023-00476-0","url":null,"abstract":"<p><strong>Aim: </strong>To compare ibuprofen and acupressure for pain relief after insertion of elastomeric orthodontic separators.</p><p><strong>Materials and methods: </strong>A randomized control clinical trial was conducted in an orthodontic clinic. A total of 75 orthodontic patients aged 12-16 years participating in the study were randomly allocated to receive either 400 mg of oral ibuprofen, applying acupressure therapy, or no pain-relief approach. Pain scores were recorded on visual analog scales (10 cm) over a week at different times (4, 10, 18, 24 h, and 1 week). The margin of equivalence was defined as 10 mm.</p><p><strong>Results: </strong>For all timepoints, the control group recorded the highest pain. For the ibuprofen and acupressure group, after 4 h, 18 h, and 1 week, no significant difference was noted. However, after 10 h, no significant difference in pain between the control and acupressure groups was noted and the ibuprofen group showed significantly lower pain. In the acupressure group, the highest pain was noted at 10 h. After this timepoint, pain progressively decreased with time and the lowest pain was noted after 1 week. In the control and ibuprofen groups, the highest pain was after 4 h, and then progressively decreased with time and the lowest pain was noted after 1 week.</p><p><strong>Conclusions: </strong>There was no significant difference in pain perception between participants using ibuprofen or acupressure and both groups recorded significantly lower pain than the control group at most of the observed timepoints. Results support the analgesic effect of the acupressure approach.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"24-32"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9739214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel concept for posterior crossbite correction : Preliminary results.","authors":"Dirk Wiechmann","doi":"10.1007/s00056-023-00468-0","DOIUrl":"10.1007/s00056-023-00468-0","url":null,"abstract":"<p><strong>Purpose: </strong>The efficiency of dentoalveolar compensation involving both jaws for posterior crossbite correction using computer-aided design/computer-aided manufacturing (CAD/CAM) expansion and compression archwires was evaluated. Treatment outcome was tested against the null hypothesis that the transverse correction achieved would be significantly smaller than planned.</p><p><strong>Methods: </strong>This retrospective study included 64 patients (mean age 23.5 years, median 17.0, minimum/maximum: 9.0/63.0, standard deviation 13.7) with uni- or bilateral posterior crossbite. In all consecutively debonded patients, expansion and/or compression archwires were used for dentoalveolar correction involving both jaws. Plaster casts prior to (T1) and following treatment (T2) with completely customized lingual appliances (CCLA) were compared with the treatment plan represented by an individual target set-up. The statistical analysis was carried out using the Schuirmann TOST (two one-sided t‑tests) equivalence test on the basis of a one-sample t‑test with α = 0.025 to one side. The non-inferiority margin was set at δ = 0.5 mm.</p><p><strong>Results: </strong>All posterior crossbites could be corrected by dentoalveolar compensation involving both jaws. The mean total correction achieved was 6.9 mm (mean maxillary expansion: 4.3 mm/mean mandibular compression: 2.6 mm) with a maximum of 12.8 mm. The transverse corrections achieved in both arches at T2 were equivalent to the planned corrections in the set-up (p < 0.001).</p><p><strong>Conclusion: </strong>The results of this study indicate that CAD/CAM expansion and compression archwires can be an efficient tool to achieve the desired correction in patients with a posterior crossbite even in more severe cases.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"1-10"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9466836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is wear time of Hawley retainers measured with microsensors related to mandibular arch stability?","authors":"Ezgi Atik, Tulin Taner, Muge Aksu","doi":"10.1007/s00056-023-00495-x","DOIUrl":"10.1007/s00056-023-00495-x","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to show a possible correlation between the mean wear time of Hawley retainers and long-term mandibular arch stability as assessed via wear time analysis with microsensors.</p><p><strong>Methods: </strong>This longitudinal retrospective study comprised 47 subjects (mean age 16.30 ± 1.06 years) having been treated with a nonextraction protocol and presenting moderate crowding at pretreatment. For retention, all patients were instructed to use a mandibular Hawley retainer for 12 months, and wear time was documented every 3 months during a posttreatment period of 6 months using TheraMon software. These individuals were divided into two groups. Those who adhered to a wear time equal to or more than 12 h/day (group 1A; N = 17) and those who complied for less than 12 h/day (group 2A; N = 30) were compared with respect to changes of the mandibular arch during the first 6 months of retention. Furthermore, a subgroup of 28 patients who completed a 12-month follow-up period were again divided into two groups: the individuals in group 1B (N = 12) adhered to a wear time equal to or more than 8 h/day, while those in group 2B (N = 16) complied for less than 8 h/day. Little's Irregularity Index, intercanine and intermolar widths, arch length, overjet, and overbite were measured on mandibular models taken at pretreatment (T0) and posttreatment (T1), as well as 6 months (T2) and 12 months (T3) after debonding. Pearson correlation test, independent samples t‑test, and Mann-Whitney U test were used for statistical evaluation.</p><p><strong>Results: </strong>From T1 to T2, group 1A and group 2A showed a significant relapse in intermolar width with a difference in the median value of 0.38 mm (p = 0.019). At the complete 12-month follow-up, the increase in Little's irregularity score was significantly greater in group 2B (2.54 ± 1.29 mm) than in group 1B (1.32 ± 1.03 mm; p = 0.012). The established wear time measurements showed significant negative correlations with the Little's irregularity score and overjet changes between T1 and T3 (p < 0.05).</p><p><strong>Conclusions: </strong>The results emphasized that the use of a retainer should not fall below a level of at least 8 h/day.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":"49-57"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41179386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early effects of α7nAChR regulation on maxillary expansion in mice : A study on osteogenesis and inflammatory factors.","authors":"Huiqi Pang, Luhua Ding, Xiaoxia Che","doi":"10.1007/s00056-024-00565-8","DOIUrl":"https://doi.org/10.1007/s00056-024-00565-8","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to investigate early effects of regulating alpha‑7 nicotinic acetylcholine receptor (α7nAChR) agonists and antagonists on maxillary expansion in mice.</p><p><strong>Methods: </strong>We allocated 36 six-week-old male C57BL/6J mice into three group: 1) expansion alone, 2) expansion plus the α7nAChR-specific agonist 3‑(2,4-dimethoxybenzylidene)-anabaseine dihydrochloride (GTS-21), and 3) expansion plus alpha-bungarotoxin (α-BTX), a competitive antagonist of α7nAChR. The groups were daily injected with saline, GTS-21 (4 mg/kg/day) or α‑BTX (1 mg/kg/day), respectively, from days 0-7. In addition, a mouse model of maxillary expansion was established. Masson's trichrome staining was used to observe morphological changes and immunohistochemistry was performed to analyze α7nAChR, interleukin (IL)-1β, IL‑6, tumor necrosis factor (TNF)-α, runt-related transcription factor 2 (RUNX2), and osteocalcin (OCN) expression in the midpalatal suture. Microcomputed tomography was used to measure midpalatal suture and palatal basal bone widths. We assessed the normal distribution of our data using the Kolmogorov-Smirnoff test and evaluated the homogeneity of variance by Levene's test, followed by a two-way ANOVA and Bonferroni tests at a significance level of P < 0.05.</p><p><strong>Results: </strong>In the GTS-21+expansion group, osteogenesis was more active in the middle palatine suture. New bone was calcified and deposited in the suture and we observed decreased IL-1β, IL‑6, and TNF‑α expression (P < 0.05). In the α‑BTX+expansion group, we observed increased proinflammatory cytokine and decreased RUNX2 and OCN expression and increased midpalatal suture and palatal basal bone widths (P < 0.05).</p><p><strong>Conclusion: </strong>Using α7nAChR agonists and antagonists to regulate the cholinergic anti-inflammatory pathway, the secretion of inflammatory factors and osteoblast markers during maxillary expansion were altered, indicating the potential for clinical modulation of maxillary palatal suture expansion.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-dependent effects of Delaire facemask therapy for class III malocclusion : Impact on maxillary sutures and palatal morphology.","authors":"Gero Stefan Michael Kinzinger, Jan Hourfar, Joana Nanina Sommer, Jörg Alexander Lisson","doi":"10.1007/s00056-024-00564-9","DOIUrl":"https://doi.org/10.1007/s00056-024-00564-9","url":null,"abstract":"<p><strong>Background and aim: </strong>Treatment effects of a combined rapid maxillary expansion (RME) and Delaire facemask (DFM) therapy have so far only been scientifically investigated through cephalometric analyses. The combination of cephalometric, dental cast and cone-beam computed tomography (CBCT) scan analysis was not yet used for investigating morphologic changes of the tooth-bearing palate. The aim of the present study was to determine whether patient age at treatment begin has an influence upon palatal length changes after RME/DFM therapy, and to what extent transverse palatal sutures contribute to these.</p><p><strong>Patients and methods: </strong>In n = 6 patients (min 10.5 years, max 14.7 years) from a total group of n = 40, CBCT datasets showing all palatal sutures were visually assessed, and palatal morphology was compared with a dental cast analysis. In addition, lateral cephalograms and dental casts of n = 40 patients were divided into two groups (PG1: < 12 years, n = 20; PG2: ≥ 12 years, n = 20), and an analysis was performed to investigate changes in the tooth-bearing palate after RME/DFM treatment.</p><p><strong>Results: </strong>The CBCT analysis showed that the median and transverse palatine sutures were always open. On the contrary, the pterygopalatomaxillary sutures were partially open only in the youngest patients. The transverse palatal suture showed age-dependent morphologic changes in the transverse and sagittal planes. The changes of the palatal width and length show clear differences between the two younger and the four older patients in the corresponding dental cast analysis. The cephalometric analysis showed that a significant improvement of the sagittal jaw relation due to ventral displacement of the maxilla during treatment occurred only in younger patients (< 12 years) despite similar initial findings in both patient groups. The dental cast analysis also revealed that changes are age-dependent: In PG1, the width increases posteriorly more than anteriorly; in PG2, this is reversed. The length increases are always significant in both patient groups, whereby the anterior, posterior, and total amounts are greater in PG1 than in PG2. In relative terms, the increases in both groups are greater posteriorly than anteriorly. There is a significant difference between the groups posteriorly and overall.</p><p><strong>Conclusions: </strong>Morphological changes of the sutures appear to have a decisive influence on the success of RME/DFM therapy. The age-dependent reactions of pterygopalatomaxillary and transverse palatine sutures represent a further main therapeutic effect of DFM treatment in addition to those described by Delaire and explain the different changes in palate length before and after the age of 12. If the maximum effect of RME/DFM treatment is desired, it should be started before the age of 12. Treatment success is age-dependent.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Possible link between the preferential unilateral chewing side and eruptive guidance of the maxillary canine germ : Cross-sectional study on panoramic radiographs.","authors":"Jesús Miguel Ticona-Flores, Guillermo Reichard-Monefeldt, Montserrat Diéguez-Pérez","doi":"10.1007/s00056-024-00566-7","DOIUrl":"https://doi.org/10.1007/s00056-024-00566-7","url":null,"abstract":"<p><strong>Aim: </strong>To determine whether unilateral preferent chewing (UPC) affects the position and angulation of the permanent maxillary canine germ on the preferred side.</p><p><strong>Materials and methods: </strong>In a retrospective cross-sectional study, medical records from children 7.91(± 0.8) years old with unilateral preferred chewing side and unilateral posterior crossbite were selected. The position of the maxillary canines was analysed by measuring the following angles and distances: the angles formed between the canine axis and the midline (PS; potential impact range > 15°), and that between the canine axis and the bicondylar line (W; potential impact range < 75°). In addition, the canine's position with respect to the lateral incisor (EK; potential impact range > II) and the distance between the canine cusp and the occlusal plane (CCOP potential impact range > 10 mm) were measured.</p><p><strong>Results: </strong>The final sample consisted of 106 radiographs; thus, a total of 212 maxillary canines were analysed. Tooth angulation on the preferred chewing side was higher for the angle PS with an average angle of 13.88° (± 7.56) and its position was more frequently found in sector II (49.1%), according to the EK analysis, compared to its contralateral that had an average of 11.75° (± 10.13) for the PS angle and a frequency of 67% in the sector I (p < 0.05 in both analyses). The data obtained for the angle W resulted in an average of 76.12° (± 9.09), while on the contralateral side it was 77.16° (± 12.56; p = 0.012). Lastly, according to the CCOP analysis, the preferred chewing side measured on average 15.3 mm (± 2.4), while on the nonpreferred side it was 15.19 mm (± 2.43; p = 0.143).</p><p><strong>Conclusions: </strong>Based on this research, UPC seems to have a certain unfavourable influence on canine position and angulation. Thus, this is another factor to consider in decision-making regarding early treatment of this development disorder.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of skeletal class III malocclusion with the Alt-RAMEC protocol and intermaxillary elastics : A retrospective cohort study.","authors":"Arife Nihan Kaya, Sema Yüksel","doi":"10.1007/s00056-024-00562-x","DOIUrl":"https://doi.org/10.1007/s00056-024-00562-x","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effects of the use of class III elastics with fixed appliances and the Alt-RAMEC procedure on dentofacial structures in patients diagnosed with skeletal class III malocclusion.</p><p><strong>Methods: </strong>The retrospective cohort study was performed on lateral cephalometric radiographs of 20 individuals (7 girls, 13 boys; mean chronological age 12.41 years) with skeletal class III malocclusion because of maxillary deficiency or maxillary deficiency and mandibular excess which were treated by using the Alt-RAMEC protocol and class III elastics. The patients were chosen from the archive of Gazi University Faculty of Dentistry, Department of Orthodontics. In order to distinguish between growth-related changes and the effects of treatment, results were compared with a control group consisting of 20 individuals (8 girls, 12 boys; mean chronological age 12 years) with similar skeletal characteristics.</p><p><strong>Results: </strong>In the treatment group, there were significant increases of 2.2°, 4.2° and 1° in the SNA, ANB and SN/GoGN angles, respectively, in contrast to the control group (p < 0.001). There was also a significant decrease of 1.9° in the SNB angle within the treatment group in contrast to the control group (p < 0.001). While the U1/SN angle increased by 1.4° in the treatment group, the L1-NB distance decreased by 0.7 mm (p < 0.01).</p><p><strong>Conclusions: </strong>The results of this study showed that application of the Alt-RAMEC protocol and class III elastics with fixed appliances showed successful results in the management of skeletal class III malocclusions, while avoiding undesirable dental effects, such as excessive lingual tipping of the lower incisors.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142815058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}